Acute baclofen diminishes resting baseline blood flow to limbic structures: a perfusion fMRI study

scientific article published on 17 April 2012

Acute baclofen diminishes resting baseline blood flow to limbic structures: a perfusion fMRI study is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.DRUGALCDEP.2012.03.016
P932PMC publication ID3770303
P698PubMed publication ID22513380

P2093author name stringCharles P O'Brien
John A Detre
Anna Rose Childress
Kanchana Jagannathan
Jesse J Suh
Teresa R Franklin
Joshua Shin
P2860cites workBaclofen suppression of cocaine self-administration: demonstration using a discrete trials procedureQ48748425
The motivation to use drugs: a psychobiological analysis of urgesQ51216475
Effects of baclofen on maintenance and reinstatement of intravenous cocaine self-administration in ratsQ51459505
Baclofen as a cocaine anti-craving medication: a preliminary clinical studyQ51526312
Baclofen attenuates the reinforcing effects of cocaine in ratsQ51561412
The GABAB receptor agonist baclofen prevents heroin-induced reinstatement of heroin-seeking behavior in ratsQ51988203
Baclofen suppresses alcohol intake and craving for alcohol in a schizophrenic alcohol-dependent patient: a case reportQ52291155
Ability of baclofen in reducing alcohol craving and intake: II--Preliminary clinical evidenceQ52893441
Ability of baclofen in reducing alcohol intake and withdrawal severity: I--Preclinical evidenceQ52893445
Randomized Comparative Trial of Nicotine Polacrilex, a Transdermal Patch, Nasal Spray, and an InhalerQ56453429
Dose-Response Effect of Baclofen in Reducing Daily Alcohol Intake in Alcohol Dependence: Secondary Analysis of a Randomized, Double-Blind, Placebo-Controlled TrialQ63464422
Targeted naltrexone treatment of early problem drinkersQ73415475
Effect of an electronic nicotine delivery device (e-Cigarette) on smoking reduction and cessation: a prospective 6-month pilot studyQ21257294
Damage to the insula disrupts addiction to cigarette smokingQ24605252
Baclofen for maintenance treatment of opioid dependence: a randomized double-blind placebo-controlled clinical trial [ISRCTN32121581]Q24799720
Novel therapeutic strategies for alcohol and drug addiction: focus on GABA, ion channels and transcranial magnetic stimulationQ26853630
Baclofen antagonizes nicotine-, cocaine-, and morphine-induced dopamine release in the nucleus accumbens of ratQ28583983
Dissociable Functions in the Medial and Lateral Orbitofrontal Cortex: Evidence from Human Neuroimaging StudiesQ29036760
How do you feel--now? The anterior insula and human awarenessQ29547250
The neural basis of drug craving: an incentive-sensitization theory of addictionQ29547475
The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10Q29547745
Pseudocontinuous arterial spin labeling reveals dissociable effects of morphine and alcohol on regional cerebral blood flowQ30474861
Continuous flow-driven inversion for arterial spin labeling using pulsed radio frequency and gradient fieldsQ30485008
Reinstated ethanol-seeking in rats is modulated by environmental context and requires the nucleus accumbens coreQ30495511
Perfusion magnetic resonance imaging with continuous arterial spin labeling: methods and clinical applications in the central nervous system.Q30579187
Empirical optimization of ASL data analysis using an ASL data processing toolbox: ASLtbxQ31126691
Perfusion fMRI for functional neuroimagingQ33230609
The GABA B agonist baclofen reduces cigarette consumption in a preliminary double-blind placebo-controlled smoking reduction study.Q33757216
Functional heterogeneity in cingulate cortex: the anterior executive and posterior evaluative regionsQ33975597
Efficacy of varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs placebo or sustained-release bupropion for smoking cessation: a randomized controlled trialQ33997418
GABA systems, benzodiazepines, and substance dependenceQ34186581
Brain reactivity to smoking cues prior to smoking cessation predicts ability to maintain tobacco abstinence.Q34197010
Reversible inactivation of the basolateral amygdala, but not the dorsolateral caudate putamen, attenuates consolidation of cocaine‐cue associative learning in a reinstatement model of drug‐seekingQ34401301
Cue dependency of nicotine self-administration and smoking.Q34498025
Self-injection of barbiturates, benzodiazepines and other sedative-anxiolytics in baboonsQ34533236
Effects of abstinence from tobacco: valid symptoms and time courseQ34577868
Multi-center trial of baclofen for abstinence initiation in severe cocaine-dependent individualsQ34607261
Emotion and motivation: the role of the amygdala, ventral striatum, and prefrontal cortexQ34659349
A potential role for GABA(B) agonists in the treatment of psychostimulant addictionQ34826755
A meta-analysis of the efficacy of over-the-counter nicotine replacementQ35075620
Targeted naltrexone for problem drinkersQ35253698
Effect of bupropion treatment on brain activation induced by cigarette-related cues in smokers.Q35545542
Effects of baclofen and mirtazapine on a laboratory model of marijuana withdrawal and relapseQ35881015
Modulation of resting brain cerebral blood flow by the GABA B agonist, baclofen: A longitudinal perfusion fMRI studyQ35947830
Dopamine transporter genotype modulation of neural responses to smoking cues: confirmation in a new cohortQ35947866
DAT genotype modulates brain and behavioral responses elicited by cigarette cues.Q35947872
Neural substrates of abstinence-induced cigarette cravings in chronic smokersQ36298171
Narp regulates long-term aversive effects of morphine withdrawalQ36925277
Effects of Varenicline on Smoking Cue–Triggered Neural and Craving ResponsesQ37094785
A VBM study demonstrating ‘apparent’ effects of a single dose of medication on T1-weighted MRIsQ37094789
Low prefrontal perfusion linked to depression symptoms in methadone-maintained opiate-dependent patientsQ37171134
Measuring nicotine dependence: a review of the Fagerstrom Tolerance QuestionnaireQ38674138
Clinical and pharmacokinetic aspects of high dose oral baclofen therapyQ39499286
Baclofen (Lioresal) intoxication report of 4 cases and review of the literatureQ40274462
Randomized, placebo-controlled trial of baclofen and gabapentin for the treatment of methamphetamine dependenceQ40320100
Cardiovascular toxicity of nicotine: implications for nicotine replacement therapyQ41495133
Baclofen antagonizes intravenous self-administration of nicotine in mice and ratsQ44129395
Brain metabolic changes during cigarette cravingQ44241351
Response of nicotine self-administration in the rat to manipulations of mu-opioid and gamma-aminobutyric acid receptors in the ventral tegmental areaQ44331544
The GABA B receptor agonists baclofen and CGP44532 decreased nicotine self-administration in the ratQ44650861
Randomized placebo-controlled trial of baclofen for cocaine dependence: preliminary effects for individuals with chronic patterns of cocaine use.Q44731806
Safety and efficacy of GABAergic medications for treating alcoholismQ44908433
Role of gamma-aminobutyric acid (GABA) and metabotropic glutamate receptors in nicotine reinforcement: potential pharmacotherapies for smoking cessationQ45150048
Baclofen prevents drug-induced reinstatement of extinguished nicotine-seeking behaviour and nicotine place preference in rodentsQ46105225
Craving is associated with smoking relapse: Findings from three prospective studiesQ46480360
Baclofen attenuates cue-induced reinstatement of alcohol-seeking behavior in Sardinian alcohol-preferring (sP) ratsQ46675644
Reproducibility of continuous arterial spin labeling perfusion MRI after 7 weeksQ48206222
Limbic activation to cigarette smoking cues independent of nicotine withdrawal: a perfusion fMRI studyQ48233950
The GABAB agonist baclofen modifies cocaine self-administration in rats.Q48340029
Hedonic and informational functions of the human orbitofrontal cortexQ48619010
P433issue1-2
P921main subjectfunctional magnetic resonance imagingQ903809
P304page(s)60-66
P577publication date2012-04-17
P1433published inDrug and Alcohol DependenceQ5308875
P1476titleAcute baclofen diminishes resting baseline blood flow to limbic structures: a perfusion fMRI study
P478volume125

Reverse relations

cites work (P2860)
Q30278728Advanced neuroimaging applied to veterans and service personnel with traumatic brain injury: state of the art and potential benefits
Q36718979Baclofen for the Treatment of Alcohol Dependence and Possible Role of Comorbid Anxiety
Q56232885Brain Functional Magnetic Resonance Imaging Cue-reactivity Can Predict Baclofen Response in Alcohol Use Disorders
Q47381358Brain substrates of early (4h) cigarette abstinence: Identification of treatment targets.
Q48352347Gamma-Hydroxybutyrate Increases Resting-State Limbic Perfusion and Body and Emotion Awareness in Humans
Q101403162Metabolite activity in the anterior cingulate cortex during a painful stimulus using functional MRS
Q30655273Neural bases of pharmacological treatment of nicotine dependence - insights from functional brain imaging: a systematic review
Q47834562Neural responses to subliminally presented cannabis and other emotionally evocative cues in cannabis-dependent individuals.
Q31031649Neuroimaging markers of glutamatergic and GABAergic systems in drug addiction: Relationships to resting-state functional connectivity
Q37679328Nipping cue reactivity in the bud: baclofen prevents limbic activation elicited by subliminal drug cues
Q38246629Targeting GABAB receptors for anti-abuse drug discovery
Q91938462The Insula: A Brain Stimulation Target for the Treatment of Addiction
Q31055323The effect of alcohol consumption on the adolescent brain: A systematic review of MRI and fMRI studies of alcohol-using youth
Q36944597The role of piriform associative connections in odor categorization.

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