| scholarly article | Q13442814 |
| P50 | author | Kevin Talbot | Q56841861 |
| Greg A Weir | Q57084100 | ||
| Mahito Nakanishi | Q57108666 | ||
| Richard Wade-Martins | Q60537481 | ||
| Ruxandra Dafinca | Q60690511 | ||
| Helen Christian | Q71317863 | ||
| Andrew Douglas | Q82286620 | ||
| Nidaa Ababneh | Q83517341 | ||
| Martin R. Turner | Q39982364 | ||
| Sally A. Cowley | Q48356810 | ||
| P2093 | author name string | Jane Vowles | |
| Alexandra Fletcher-Jones | |||
| Cathy Browne | |||
| Jakub Scaber | |||
| Tatjana Lalic | |||
| P2860 | cites work | RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention | Q24562489 |
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| Large C9orf72 hexanucleotide repeat expansions are seen in multiple neurodegenerative syndromes and are more frequent than expected in the UK population. | Q36666933 | ||
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| Increased expression of p62 in expanded polyglutamine-expressing cells and its association with polyglutamine inclusions. | Q40513609 | ||
| Targeting Bcl-2-IP3 receptor interaction to reverse Bcl-2's inhibition of apoptotic calcium signals | Q40894970 | ||
| The role of calcium-binding proteins in selective motoneuron vulnerability in amyotrophic lateral sclerosis | Q41413618 | ||
| p62 Is a common component of cytoplasmic inclusions in protein aggregation diseases | Q42184099 | ||
| An MND/ALS phenotype associated with C9orf72 repeat expansion: abundant p62-positive, TDP-43-negative inclusions in cerebral cortex, hippocampus and cerebellum but without associated cognitive decline. | Q42499208 | ||
| Endogenous calcium buffering in motoneurones of the nucleus hypoglossus from mouse | Q48423445 | ||
| A C9orf72 promoter repeat expansion in a Flanders-Belgian cohort with disorders of the frontotemporal lobar degeneration-amyotrophic lateral sclerosis spectrum: a gene identification study | Q48791547 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P433 | issue | 8 | |
| P921 | main subject | endoplasmic reticulum | Q79927 |
| patient | Q181600 | ||
| amyotrophic lateral sclerosis | Q206901 | ||
| P304 | page(s) | 2063-2078 | |
| P577 | publication date | 2016-04-20 | |
| P1433 | published in | Stem Cells | Q15724411 |
| P1476 | title | C9orf72 Hexanucleotide Expansions Are Associated with Altered Endoplasmic Reticulum Calcium Homeostasis and Stress Granule Formation in Induced Pluripotent Stem Cell-Derived Neurons from Patients with Amyotrophic Lateral Sclerosis and Frontotemporal | |
| P478 | volume | 34 |
| Q55190076 | 2D versus 3D human induced pluripotent stem cell-derived cultures for neurodegenerative disease modelling. |
| Q48261139 | A Simplified Method for Generating Purkinje Cells from Human-Induced Pluripotent Stem Cells. |
| Q47230701 | A zebrafish model for C9orf72 ALS reveals RNA toxicity as a pathogenic mechanism. |
| Q33845021 | Abnormalities of Mitochondrial Dynamics in Neurodegenerative Diseases |
| Q98463519 | Altered serum protein levels in frontotemporal dementia and amyotrophic lateral sclerosis indicate calcium and immunity dysregulation |
| Q49831939 | Alzheimer's Disease: A Special Collection |
| Q33796347 | Amyotrophic lateral sclerosis patient iPSC-derived astrocytes impair autophagy via non-cell autonomous mechanisms |
| Q64930933 | Astrocytes and Microglia as Potential Contributors to the Pathogenesis of C9orf72 Repeat Expansion-Associated FTLD and ALS. |
| Q33577239 | Bidirectional nucleolar dysfunction in C9orf72 frontotemporal lobar degeneration |
| Q47882860 | C9ORF72 GGGGCC repeat-associated non-AUG translation is upregulated by stress through eIF2α phosphorylation. |
| Q39520699 | C9ORF72 is a GDP/GTP exchange factor for Rab8 and Rab39 and regulates autophagy |
| Q47841147 | C9ORF72 repeat expansion causes vulnerability of motor neurons to Ca2+-permeable AMPA receptor-mediated excitotoxicity |
| Q38288577 | C9orf72 and RAB7L1 regulate vesicle trafficking in amyotrophic lateral sclerosis and frontotemporal dementia |
| Q64948055 | C9orf72-mediated ALS and FTD: multiple pathways to disease. |
| Q90524749 | CRISPR-Cas9 Screens Identify the RNA Helicase DDX3X as a Repressor of C9ORF72 (GGGGCC)n Repeat-Associated Non-AUG Translation |
| Q52430610 | CRISPR-Cas9 screens in human cells and primary neurons identify modifiers of C9ORF72 dipeptide-repeat-protein toxicity. |
| Q47739915 | Calcium dysregulation and Cdk5-ATM pathway involved in a mouse model of fragile X-associated tremor/ataxia syndrome |
| Q64956244 | Cellular α-synuclein pathology is associated with bioenergetic dysfunction in Parkinson's iPSC-derived dopamine neurons. |
| Q47868914 | Current Advances and Limitations in Modeling ALS/FTD in a Dish Using Induced Pluripotent Stem Cells |
| Q38653861 | ER stress and the unfolded protein response in neurodegeneration |
| Q39316849 | Energy Homeostasis and Abnormal RNA Metabolism in Amyotrophic Lateral Sclerosis |
| Q41488989 | Excess α-synuclein compromises phagocytosis in iPSC-derived macrophages |
| Q41458537 | Failure to Deliver and Translate-New Insights into RNA Dysregulation in ALS. |
| Q40127266 | Fine-Tuning ER Stress Signal Transducers to Treat Amyotrophic Lateral Sclerosis |
| Q89863711 | Functional Roles of Long Non-coding RNAs in Motor Neuron Development and Disease |
| Q33559744 | Genetic Correction of SOD1 Mutant iPSCs Reveals ERK and JNK Activated AP1 as a Driver of Neurodegeneration in Amyotrophic Lateral Sclerosis |
| Q88577959 | Insights into C9ORF72-Related ALS/FTD from Drosophila and iPSC Models |
| Q41325226 | MAPT Genetic Variation and Neuronal Maturity Alter Isoform Expression Affecting Axonal Transport in iPSC-Derived Dopamine Neurons. |
| Q91867885 | Metabolic Alteration and Amyotrophic Lateral Sclerosis Outcome: A Systematic Review |
| Q98224396 | Mitochondrial Dysfunction, Neurogenesis, and Epigenetics: Putative Implications for Amyotrophic Lateral Sclerosis Neurodegeneration and Treatment |
| Q55398317 | Modeling Protein Aggregation and the Heat Shock Response in ALS iPSC-Derived Motor Neurons. |
| Q38741408 | Modeling the C9ORF72 repeat expansion mutation using human induced pluripotent stem cells |
| Q61816243 | Molecular Mechanisms of Neurodegeneration Related to Hexanucleotide Repeat Expansion |
| Q91970420 | Motor Neuron Susceptibility in ALS/FTD |
| Q39445097 | Multifunctional molecule ERp57: From cancer to neurodegenerative diseases |
| Q57150956 | Neurodegeneration in SCA14 is associated with increased PKCγ kinase activity, mislocalization and aggregation |
| Q45874124 | Neuroprotective Potential of Cell-Based Therapies in ALS: From Bench to Bedside |
| Q38952327 | Pathogenic determinants and mechanisms of ALS/FTD linked to hexanucleotide repeat expansions in the C9orf72 gene |
| Q98238116 | Pharmacological activation of the circadian component REV-ERB inhibits HIV-1 replication |
| Q41991266 | Proteostasis disturbance in amyotrophic lateral sclerosis |
| Q58700548 | RIPK1 is a critical modulator of both tonic and TLR-responsive inflammatory and cell death pathways in human macrophage differentiation |
| Q47423589 | RNA binding proteins and the pathological cascade in ALS/FTD neurodegeneration |
| Q92597079 | Reduced autophagy upon C9ORF72 loss synergizes with dipeptide repeat protein toxicity in G4C2 repeat expansion disorders |
| Q51731758 | Stem Cell modeling of Mitochondrial Parkinsonism reveals key functions of OPA1. |
| Q92378165 | Studying Human Neurological Disorders Using Induced Pluripotent Stem Cells: From 2D Monolayer to 3D Organoid and Blood Brain Barrier Models |
| Q49905442 | Synaptic dysfunction and altered excitability in C9ORF72 ALS/FTD. |
| Q89741641 | Synaptotagmin 13 is neuroprotective across motor neuron diseases |
| Q39410246 | The Endoplasmic Reticulum Unfolded Protein Response in Neurodegenerative Disorders and Its Potential Therapeutic Significance |
| Q41023936 | The Role of BiP Retrieval by the KDEL Receptor in the Early Secretory Pathway and its Effect on Protein Quality Control and Neurodegeneration |
| Q64069200 | The Role of the Antioxidant Response in Mitochondrial Dysfunction in Degenerative Diseases: Cross-Talk between Antioxidant Defense, Autophagy, and Apoptosis |
| Q88789207 | Translation of dipeptide repeat proteins from the C9ORF72 expanded repeat is associated with cellular stress |
| Q37507550 | Variant U1 snRNAs are implicated in human pluripotent stem cell maintenance and neuromuscular disease. |
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