| scholarly article | Q13442814 |
| P819 | ADS bibcode | 1992PNAS...89.7806G |
| P356 | DOI | 10.1073/PNAS.89.16.7806 |
| P932 | PMC publication ID | 49800 |
| P698 | PubMed publication ID | 1502199 |
| P5875 | ResearchGate publication ID | 21653920 |
| P50 | author | Detlev Ganten | Q113819 |
| Michael Bader | Q37611575 | ||
| P2093 | author name string | Paul M | |
| Wagner J | |||
| Michel JB | |||
| Zeh K | |||
| Ganten U | |||
| Zimmermann F | |||
| Hilgenfeldt U | |||
| Ruf P | |||
| P2860 | cites work | Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: differential expression of tau protein mRNAs in human brain | Q24300015 |
| Purification of mouse immunoglobulin heavy-chain messenger RNAs from total myeloma tumor RNA | Q29547801 | ||
| Structure and expression of the human angiotensinogen gene. Identification of a unique and highly active promoter | Q33254534 | ||
| Expression of the DBA/2J Ren-2 gene in the adrenal gland of transgenic mice. | Q33589619 | ||
| Generation of transgenic mice with elevated blood pressure by introduction of the rat renin and angiotensinogen genes | Q33669930 | ||
| Response of plasma prorenin and active renin to chronic and acute alterations of renin secretion in normal humans. Studies using a direct immunoradiometric assay | Q34567059 | ||
| Structure of the human renin gene | Q36586902 | ||
| Transgenic rats: new animal models in hypertension research. Invited lecture | Q37745698 | ||
| Multiple forms of human renin. Purification and characterization | Q39660604 | ||
| Tissue-specific expression of the human renin gene in transgenic mice | Q44226139 | ||
| Tamm-Horsfall protein-mRNA synthesis is localized to the thick ascending limb of Henle's loop in rat kidney | Q45135282 | ||
| Fulminant hypertension in transgenic rats harbouring the mouse Ren-2 gene | Q59066147 | ||
| Components of the renin-angiotensin system in the cerebrospinal fluid of rats and dogs with special consideration of the origin and the fate of angiotensin II | Q67248656 | ||
| Modulation of mouse renin gene expression by dietary sodium chloride intake in one-gene, two-gene and transgenic animals | Q69563179 | ||
| Direct immunometric assay of active renin in human plasma | Q69855629 | ||
| Measurement and characterization of angiotensin peptides in plasma | Q70055639 | ||
| Role of angiotensinogen in blood pressure homeostasis | Q70310779 | ||
| P433 | issue | 16 | |
| P407 | language of work or name | English | Q1860 |
| P1104 | number of pages | 5 | |
| P304 | page(s) | 7806-7810 | |
| P577 | publication date | 1992-08-01 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Species specificity of renin kinetics in transgenic rats harboring the human renin and angiotensinogen genes | |
| P478 | volume | 89 |
| Q33625889 | A current view of brain renin-angiotensin system: Is the (pro)renin receptor the missing link? |
| Q38333337 | A novel distal enhancer confers chorionic expression on the human renin gene. |
| Q91712173 | Activation of the Human Angiotensin-(1-12)-Chymase Pathway in Rats With Human Angiotensinogen Gene Transcripts |
| Q37058900 | Aliskiren--an orally active renin inhibitor. Review of pharmacology, pharmacodynamics, kinetics, and clinical potential in the treatment of hypertension |
| Q28278108 | Aliskiren--mode of action and preclinical data |
| Q37104856 | Aliskiren-hydrochlorothiazide combination for the treatment of hypertension |
| Q37111865 | Aliskiren: clinical experience and future perspectives of renin inhibition |
| Q28272666 | Aliskiren: the first renin inhibitor for clinical treatment |
| Q35791591 | Angiotensin II induces connective tissue growth factor gene expression via calcineurin-dependent pathways |
| Q24302066 | Angiotensin II-induced sudden arrhythmic death and electrical remodeling |
| Q92336055 | Animal Models of Hypertension: A Scientific Statement From the American Heart Association |
| Q38499967 | Caloric restriction ameliorates angiotensin II-induced mitochondrial remodeling and cardiac hypertrophy |
| Q36902297 | Cardiac angiotensin-(1-12) expression and systemic hypertension in rats expressing the human angiotensinogen gene |
| Q45205031 | Cardiac gene expression profile in rats with terminal heart failure and cachexia |
| Q42746488 | Characterization of a stable, hypertensive rat model suitable for the consecutive evaluation of human renin inhibitors |
| Q37352071 | Chronic hypertension and altered baroreflex responses in transgenic mice containing the human renin and human angiotensinogen genes. |
| Q33393559 | Clinical features of malignant hypertension with thrombotic microangiopathy. |
| Q72118268 | Cortical expression of the human angiotensinogen gene in the kidney of transgenic mice |
| Q27684098 | Discovery of VTP-27999, an Alkyl Amine Renin Inhibitor with Potential for Clinical Utility |
| Q27023126 | Divergent mechanism regulating fluid intake and metabolism by the brain renin-angiotensin system |
| Q28744563 | Effects of aliskiren on stroke in rats expressing human renin and angiotensinogen genes |
| Q46795293 | Exacerbation of acute kidney injury by bone marrow stromal cells from rats with persistent renin-angiotensin system activation. |
| Q35747594 | Expression of renin in large arteries outside the kidney revealed by human renin promoter/LacZ transgenic mouse |
| Q72633869 | Expression of the human renin gene in transgenic mice throughout ontogeny |
| Q56963881 | Expression of the mouse ren-2 gene in the small intestine is regulated by food intake |
| Q33709310 | Genetically modified animals in pharmacological research: future trends |
| Q48159793 | Human angiotensinogen is highly expressed in astrocytes in human cortical grafts |
| Q36443015 | Hypertension, kidney, and transgenics: a fresh perspective |
| Q34022862 | Hypertensive emergencies |
| Q52122720 | In vitro formation of tetraploid rat blastocysts after fusion of two-cell embryos. |
| Q52875203 | Increased expression of (pro)renin receptor does not cause hypertension or cardiac and renal fibrosis in mice. |
| Q38846247 | Intracrine angiotensin II functions originate from noncanonical pathways in the human heart |
| Q39641307 | Intrarenal renin angiotensin system revisited: role of megalin-dependent endocytosis along the proximal nephron |
| Q42919974 | Levosimendan improves cardiac function and survival in rats with angiotensin II-induced hypertensive heart failure |
| Q56985246 | Low-dose renin inhibitor and low-dose AT1-receptor blocker therapy ameliorate target-organ damage in rats harbouring human renin and angiotensinogen genes |
| Q40337770 | Mechanism of cAMP regulation of renin gene transcription by proximal promoter |
| Q43197352 | Metabolomics in angiotensin II-induced cardiac hypertrophy |
| Q40335417 | Molecular mechanism of transcriptional activation of angiotensinogen gene by proximal promoter |
| Q30527781 | Multiphoton imaging of the glomerular permeability of angiotensinogen |
| Q43923220 | New elements in human renin promoter involved in cell-specific expression |
| Q37702782 | New insights into the renoprotective actions of the renin inhibitor aliskiren in experimental renal disease |
| Q37741787 | New pharmacological treatments for improving renal outcomes in diabetes |
| Q37812140 | Pharmacokinetic, pharmacodynamic and clinical evaluation of aliskiren for hypertension treatment |
| Q37175181 | Preeclampsia risk and angiotensinogen polymorphisms M235T and AGT -217 in African American and Caucasian women |
| Q41424196 | Proteolytic processing of human prorenin in renal and non-renal tissues |
| Q34801804 | Renin and cardiovascular disease: Worn-out path, or new direction |
| Q24299673 | Renin increases mesangial cell transforming growth factor-beta1 and matrix proteins through receptor-mediated, angiotensin II-independent mechanisms |
| Q38075571 | Renin inhibition in the treatment of diabetic kidney disease |
| Q46727866 | Renin inhibition with aliskiren |
| Q37145704 | Renin inhibition with aliskiren in hypertension: focus on aliskiren/hydrochlorothiazide combination therapy |
| Q43080314 | Resveratrol induces mitochondrial biogenesis and ameliorates Ang II-induced cardiac remodeling in transgenic rats harboring human renin and angiotensinogen genes |
| Q34940129 | Rodent models of cardiopulmonary disease: their potential applicability in studies of air pollutant susceptibility |
| Q60394885 | Structural basis for the specificity of renin-mediated angiotensinogen cleavage. |
| Q46703443 | The predominant role of brain angiotensinogen and angiotensin in environmentally induced hypertension |
| Q38571062 | The putative (pro)renin receptor blocker HRP fails to prevent (pro)renin signaling |
| Q37019887 | The renin angiotensin system in the development of cardiovascular disease: role of aliskiren in risk reduction |
| Q40952073 | The renin-angiotensin system in transgenic rats |
| Q52264334 | Tissue targeting of angiotensin peptides. |
| Q41133270 | Transactivation of the human renin promoter by the cyclic AMP/protein kinase A pathway is mediated by both cAMP-responsive element binding protein-1 (CREB)-dependent and CREB-independent mechanisms in Calu-6 cells |
| Q41074600 | Transgenesis in rats: technical aspects and models |
| Q33799227 | Transgenic and knockout models in renin-angiotensin system |
| Q33862497 | Transgenic animal models for neuropharmacology |
| Q52981348 | Transgenic animal models for the functional analysis of vasoactive peptides. |
| Q40781025 | Transgenic animals as models for human disease--report of an EC Study Group |
| Q40377650 | Transgenic animals in the study of blood pressure regulation and hypertension. |
| Q36295015 | Transgenic modifications of the rat genome |
| Q37139367 | Update on tissue renin-angiotensin systems |
| Q34590536 | Use of genetically engineered mice in drug discovery and development: wielding Occam's razor to prune the product portfolio |
| Q37642931 | What is the role of renin inhibition in the treatment of diabetic kidney disease? |
| Q82770377 | [Debate concerning the optimal blockage of the renin-angiotensin system] |
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