VEGF controls lung Th2 inflammation via the miR-1-Mpl (myeloproliferative leukemia virus oncogene)-P-selectin axis.

scientific article published on 16 September 2013

VEGF controls lung Th2 inflammation via the miR-1-Mpl (myeloproliferative leukemia virus oncogene)-P-selectin axis. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1084/JEM.20121200
P932PMC publication ID3782056
P698PubMed publication ID24043765
P5875ResearchGate publication ID256666579

P50authorChun Geun LeeQ56810022
P2093author name stringQing Liu
Jack A Elias
Farida Ahangari
Seyedtaghi Takyar
Lauren Cohn
Naiqian Niu
Hema Vasavada
Jian-ge Zhang
P2860cites workGene expression of vascular endothelial growth factor and its receptors and angiogenesis in bronchial asthmaQ73993463
Thrombopoietin and its receptor, c-mpl, are constitutively expressed by mouse liver endothelial cells: evidence of thrombopoietin as a growth factor for liver endothelial cellsQ74106161
Eosinophils promote allergic disease of the lung by regulating CD4(+) Th2 lymphocyte functionQ74481539
A dual function anti-leukemic agent with anti-thrombotic activityQ74540310
P-selectin mediates IL-13-induced eosinophil transmigration but not eotaxin generation in vivo: a comparative study with IL-4-elicited responsesQ78785468
A novel pathway that regulates inflammatory disease in the respiratory tractQ79880540
Endothelial STAT3 is essential for the protective effects of HO-1 in oxidant-induced lung injuryQ95814567
Systematic identification of mRNAs recruited to argonaute 2 by specific microRNAs and corresponding changes in transcript abundanceQ21090092
Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylationQ24310618
miR-126 regulates angiogenic signaling and vascular integrityQ24569770
Experimental strategies for microRNA target identificationQ24603494
Proinflammatory role for let-7 microRNAS in experimental asthmaQ24604272
MicroRNAs: target recognition and regulatory functionsQ24609584
Antagonism of microRNA-126 suppresses the effector function of TH2 cells and the development of allergic airways diseaseQ24644352
An integrated approach for experimental target identification of hypoxia-induced miR-210Q24646947
Drosophila let-7 microRNA is required for remodeling of the neuromusculature during metamorphosisQ24655091
The endothelial-specific microRNA miR-126 governs vascular integrity and angiogenesisQ24656947
MicroRNA expression profiling of single whole embryonic stem cellsQ25256860
Argonaute2 is the catalytic engine of mammalian RNAiQ27860545
The biology of VEGF and its receptorsQ27860704
Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAsQ27861053
MicroRNA-92a controls angiogenesis and functional recovery of ischemic tissues in miceQ28115423
Let-7 microRNA-mediated regulation of IL-13 and allergic airway inflammationQ28238669
Pigment epithelium-derived factor (PEDF) is an endogenous antiinflammatory factorQ28567494
Getting to the site of inflammation: the leukocyte adhesion cascade updatedQ29547271
Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveysQ29615415
MicroRNAs regulate brain morphogenesis in zebrafishQ29617530
MicroRNA-mediated integration of haemodynamics and Vegf signalling during angiogenesisQ30495845
Natural selection on human microRNA binding sites inferred from SNP dataQ31071445
Cytokine-mediated deployment of SDF-1 induces revascularization through recruitment of CXCR4+ hemangiocytesQ33371036
MicroRNA-21 is up-regulated in allergic airway inflammation and regulates IL-12p35 expressionQ33426268
Angioplasticity in asthmaQ33668427
Angiopoietin-1 and vascular endothelial growth factor regulation of leukocyte adhesion to endothelial cells: role of nuclear receptor-77Q34280003
Making or breaking the heart: from lineage determination to morphogenesisQ34567781
How do microRNAs regulate gene expression?Q34573729
Identification of miRNA targets with stable isotope labeling by amino acids in cell culture.Q35130372
Triple selectin knockout (ELP-/-) mice fail to develop OVA-induced acute asthma phenotypeQ35206029
Activation of beta1 integrins on blood eosinophils by P-selectinQ35528037
Quantitative functions of Argonaute proteins in mammalian development.Q35882150
EBV and human microRNAs co-target oncogenic and apoptotic viral and human genes during latencyQ35932258
Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung.Q36209876
A biochemical approach to identifying microRNA targetsQ36288545
Eosinophil adhesion to nasal polyp endothelium is P-selectin-dependentQ36363415
Vascular endothelial growth factor in the lungQ36364992
Intrinsic defect in T cell production of interleukin (IL)-13 in the absence of both IL-5 and eotaxin precludes the development of eosinophilia and airways hyperreactivity in experimental asthmaQ36369722
Allergic pulmonary inflammation in mice is dependent on eosinophil-induced recruitment of effector T cellsQ36509887
Strain-specific requirement for eosinophils in the recruitment of T cells to the lung during the development of allergic asthmaQ36699742
Role of thrombopoietin in mast cell differentiationQ36806176
Eosinophil trafficking in allergy and asthma.Q36811728
Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesisQ36893701
Treatment strategies for allergy and asthmaQ37084502
Vascular endothelial growth factor of the lung: friend or foeQ37158665
Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13-induced tissue responses and apoptosisQ37273123
New therapies for asthma: is there any progress?Q37765700
The many paths to asthma: phenotype shaped by innate and adaptive immunityQ37766451
The thrombopoietin/MPL pathway in hematopoiesis and leukemogenesisQ37848274
Therapies for allergic inflammation: refining strategies to induce toleranceQ38007833
Tandem array-based expression screens identify host mRNA targets of virus-encoded microRNAsQ38357974
Endothelial cells are central orchestrators of cytokine amplification during influenza virus infectionQ38525056
Ribosomal protein L11 recruits miR-24/miRISC to repress c-Myc expression in response to ribosomal stressQ38630478
AU-rich-element-mediated upregulation of translation by FXR1 and Argonaute 2.Q40154871
Small interfering RNA targeting heme oxygenase-1 enhances ischemia-reperfusion-induced lung apoptosis.Q40541858
Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin productionQ40849898
Basic fibroblast growth factor in asthma: measurement in bronchoalveolar lavage fluid basally and following allergen challengeQ42499243
Proangiogenic activity in bronchoalveolar lavage fluid from patients with asthmaQ42511846
E- and P-selectins are essential for the development of cockroach allergen-induced airway responsesQ44092320
IgE cross-linking or lipopolysaccharide treatment induces recruitment of Th2 cells to the lung in the absence of specific antigenQ44209282
Associations of vascular endothelial growth factor (VEGF) with adhesion and inflammation molecules in a healthy populationQ44809955
Inhibition of pulmonary eosinophilia in P-selectin- and ICAM-1-deficient mice.Q45932018
Inhibition of eosinophil rolling and recruitment in P-selectin- and intracellular adhesion molecule-1-deficient mice.Q46233274
Lesion-targeted thrombopoietin potentiates vasculogenesis by enhancing motility and enlivenment of transplanted endothelial progenitor cells via activation of Akt/mTOR/p70S6kinase signaling pathwayQ46387376
IL-13 receptor alpha2 selectively inhibits IL-13-induced responses in the murine lungQ50232098
Megakaryocytes constitute a functional component of a plasma cell niche in the bone marrow.Q50550577
Thrombopoietin gene transfer-mediated enhancement of angiogenic responses to acute ischemiaQ64378483
Platelets promote eosinophil adhesion of patients with asthma to endothelium under flow conditionsQ73167341
Expression of vascular endothelial growth factor, basic fibroblast growth factor, and angiogenin immunoreactivity in asthmatic airways and its relationship to angiogenesisQ73431447
P4510describes a project that usesImageJQ1659584
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectleukemiaQ29496
inflammationQ101991
P304page(s)1993-2010
P577publication date2013-09-16
P1433published inJournal of Experimental MedicineQ3186912
P1476titleVEGF controls lung Th2 inflammation via the miR-1-Mpl (myeloproliferative leukemia virus oncogene)-P-selectin axis
P478volume210

Reverse relations

cites work (P2860)
Q37555805A plasma microRNA signature as a biomarker for acquired aplastic anemia
Q52936785Aryl hydrocarbon receptor agonists upregulate VEGF secretion from bronchial epithelial cells.
Q39614255Blockade of β-catenin signaling attenuates toluene diisocyanate-induced experimental asthma
Q26766294Challenges and Current Efforts in the Development of Biomarkers for Chronic Inflammatory and Remodeling Conditions of the Lungs
Q42334374Circulating microRNAs: promising biomarkers in aplastic anemia
Q28067306Delivery of RNAi Therapeutics to the Airways-From Bench to Bedside
Q36614187Endothelial inflammatory transcriptional responses to an altered plasma exposome following inhalation of diesel emissions
Q28083520Epigenome-modifying tools in asthma
Q46506454Leukotriene B4 Receptor 2 Is Critical for the Synthesis of Vascular Endothelial Growth Factor in Allergen-Stimulated Mast Cells
Q47691629Lung Endothelial MicroRNA-1 Regulates Tumor Growth and Angiogenesis
Q35866988Luteolin Inhibits Ischemia/Reperfusion-Induced Myocardial Injury in Rats via Downregulation of microRNA-208b-3p
Q64972425MicroRNA expression profile in retina and choroid in oxygen-induced retinopathy model.
Q50091780MicroRNA.
Q38259337MicroRNA: potential biomarkers and therapeutic targets for allergic asthma?
Q38185939MicroRNAs in allergy and asthma
Q38212798MicroRNAs in cervical cancer: evidences for a miRNA profile deregulated by HPV and its impact on radio-resistance.
Q26744763Molecular Background of miRNA Role in Asthma and COPD: An Updated Insight
Q92971410Next Generation Sequencing for Long Non-coding RNAs Profile for CD4+ T Cells in the Mouse Model of Acute Asthma
Q57916044Physiological Role of Vascular Endothelial Growth Factors as Homeostatic Regulators
Q38764534Promoter Assay Using Luciferase Reporter Gene in the A549 Cell Line
Q42358583Redox imaging of inflammation in asthma
Q38928339Role of chitinase 3-like-1 and semaphorin 7a in pulmonary melanoma metastasis
Q39614262The receptor for advanced glycation end products is required for β-catenin stabilization in a chemical-induced asthma model
Q58570764Transcriptomics in lung tissue upon respiratory syncytial virus infection reveals aging as important modulator of immune activation and matrix maintenance
Q33732168Update in asthma 2013
Q33721685Vascular endothelial growth factor signaling in hypoxia and inflammation
Q38932407microRNA and Allergy
Q28082698ncRNA-regulated immune response and its role in inflammatory lung diseases

Search more.