scholarly article | Q13442814 |
review article | Q7318358 |
P356 | DOI | 10.1002/JCB.23089 |
P8608 | Fatcat ID | release_txdnsszahrfjbc22n6bw7a3q2y |
P698 | PubMed publication ID | 21360575 |
P5875 | ResearchGate publication ID | 50229536 |
P2093 | author name string | Fu-Sheng Chou | |
James C Mulloy | |||
P2860 | cites work | Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin | Q24316187 |
Molecular cloning and characterization of MPL, the human homolog of the v-mpl oncogene: identification of a member of the hematopoietic growth factor receptor superfamily | Q24564819 | ||
c-mpl mutations are the cause of congenital amegakaryocytic thrombocytopenia | Q28141146 | ||
A putative truncated cytokine receptor gene transduced by the myeloproliferative leukemia virus immortalizes hematopoietic progenitors | Q28243227 | ||
Mpl receptor defect leads to earlier appearance of hematopoietic cells/hematopoietic stem cells in the Aorta-Gonad-Mesonephros region, with increased apoptosis | Q28504451 | ||
Circulating thrombopoietin as an in vivo growth factor for blast cells in acute myeloid leukemia | Q33369381 | ||
Posttransplant thrombopoiesis predicts survival in patients undergoing autologous hematopoietic progenitor cell transplantation | Q33375947 | ||
Congenital amegakaryocytic thrombocytopenia-3 novel c-MPL mutations and their phenotypic correlations | Q33377857 | ||
Thrombocytopenia in c-mpl-deficient mice | Q33491977 | ||
Distinct regions of c-Mpl cytoplasmic domain are coupled to the JAK-STAT signal transduction pathway and Shc phosphorylation | Q34207417 | ||
AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis | Q34299077 | ||
MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia | Q34770384 | ||
Thrombopoietin induces HOXA9 nuclear transport in immature hematopoietic cells: potential mechanism by which the hormone favorably affects hematopoietic stem cells | Q35663894 | ||
Hematopoietic stem cell deficiencies in mice lacking c-Mpl, the receptor for thrombopoietin. | Q35800066 | ||
Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype. | Q35847967 | ||
The role of apoptosis in the regulation of hematopoietic stem cells: Overexpression of Bcl-2 increases both their number and repopulation potential | Q36375771 | ||
Sustained ex vivo expansion of hematopoietic stem cells mediated by thrombopoietin | Q36417126 | ||
AML1/RUNX1 works as a negative regulator of c-Mpl in hematopoietic stem cells | Q37142554 | ||
Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter | Q37347018 | ||
Combined administration of recombinant human megakaryocyte growth and development factor and granulocyte colony-stimulating factor enhances multilineage hematopoietic reconstitution in nonhuman primates after radiation-induced marrow aplasia | Q37354699 | ||
Balancing dormant and self-renewing hematopoietic stem cells | Q37610592 | ||
Thrombopoietin expands hematopoietic stem cells after transplantation | Q39738286 | ||
Thrombopoietin/MPL signaling regulates hematopoietic stem cell quiescence and interaction with the osteoblastic niche. | Q39997716 | ||
Continuous expression of Bcl-xL protein during megakaryopoiesis is post-translationally regulated by thrombopoietin-mediated Akt activation, which prevents the cleavage of Bcl-xL. | Q40153818 | ||
Antiapoptotic protein Bcl-x(L) is up-regulated during megakaryocytic differentiation of CD34(+) progenitors but is absent from senescent megakaryocytes. | Q40802790 | ||
cMpl ligand is a humoral regulator of megakaryocytopoiesis | Q41460906 | ||
Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo | Q41460916 | ||
The human stem cell hierarchy is defined by a functional dependence on Mcl-1 for self-renewal capacity | Q43043792 | ||
MPL515 mutations in myeloproliferative and other myeloid disorders: a study of 1182 patients | Q44008600 | ||
Thrombopoietin stimulates Hoxb4 expression: an explanation for the favorable effects of TPO on hematopoietic stem cells. | Q46003161 | ||
The role of apoptosis in the development of AGM hematopoietic stem cells revealed by Bcl-2 overexpression. | Q47205774 | ||
Dual role of Mpl receptor during the establishment of definitive hematopoiesis. | Q50894334 | ||
MPLW515L mutation in acute megakaryoblastic leukaemia. | Q53313140 | ||
A prototype nonpeptidyl, hydrazone class, thrombopoietin receptor agonist, SB-559457, is toxic to primary human myeloid leukemia cells. | Q53362508 | ||
Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells. | Q54679983 | ||
Critical Role of Thrombopoietin in Maintaining Adult Quiescent Hematopoietic Stem Cells | Q57362319 | ||
P433 | issue | 6 | |
P921 | main subject | hemopoiesis | Q919283 |
P304 | page(s) | 1491-1498 | |
P577 | publication date | 2011-06-01 | |
P1433 | published in | Journal of Cellular Biochemistry | Q6294917 |
P1476 | title | The thrombopoietin/MPL pathway in hematopoiesis and leukemogenesis | |
P478 | volume | 112 |
Q35952453 | Blockade of Thrombopoietin Reduces Organ Damage in Experimental Endotoxemia and Polymicrobial Sepsis |
Q44026903 | CD34 Antigen and the MPL Receptor Expression Defines a Novel Class of Human Cord Blood-Derived Primitive Hematopoietic Stem Cells |
Q37599843 | DNMT3A Arg882 mutation drives chronic myelomonocytic leukemia through disturbing gene expression/DNA methylation in hematopoietic cells |
Q33414087 | Eltrombopag can overcome the anti-megakaryopoietic effects of lenalidomide without increasing proliferation of the malignant myelodysplastic syndrome/acute myelogenous leukemia clone |
Q33401421 | Eltrombopag inhibits the proliferation of leukemia cells via reduction of intracellular iron and induction of differentiation |
Q24626423 | Exome sequencing identifies MPL as a causative gene in familial aplastic anemia |
Q21296679 | Hematopoietic stem cell development, niches, and signaling pathways |
Q39016705 | Identification of a new Mpl-interacting protein, Atp5d |
Q26779936 | Inflammation as a Driver of Clonal Evolution in Myeloproliferative Neoplasm |
Q36413813 | Inhibition of poly(ADP-ribose) polymerase 1 protects against acute myeloid leukemia by suppressing the myeloproliferative leukemia virus oncogene |
Q42244901 | Interleukin-2-regulatory T cell axis critically regulates maintenance of hematopoietic stem cells. |
Q42315227 | Kras is Required for Adult Hematopoiesis |
Q38266904 | Signal, transduction, and the hematopoietic stem cell |
Q36356216 | TWIST-1 promotes cell growth, drug resistance and progenitor clonogenic capacities in myeloid leukemia and is a novel poor prognostic factor in acute myeloid leukemia |
Q34737531 | The thrombopoietin receptor, MPL, is critical for development of a JAK2V617F-induced myeloproliferative neoplasm |
Q21296645 | Thrombopoietin as biomarker and mediator of cardiovascular damage in critical diseases |
Q41090525 | Transcriptome Analysis of Minimal Residual Disease in Subtypes of Pediatric B Cell Acute Lymphoblastic Leukemia |
Q37194990 | VEGF controls lung Th2 inflammation via the miR-1-Mpl (myeloproliferative leukemia virus oncogene)-P-selectin axis. |
Q41672333 | Whole genome gene expression changes and hematological effects of rikkunshito in patients with advanced non-small cell lung cancer receiving first line chemotherapy. |
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