Acquisition of Functional Antibodies That Block the Binding of Erythrocyte-Binding Antigen 175 and Protection Against Plasmodium falciparum Malaria in Children

scientific article published on July 2015

Acquisition of Functional Antibodies That Block the Binding of Erythrocyte-Binding Antigen 175 and Protection Against Plasmodium falciparum Malaria in Children is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/CID/CIV525
P932PMC publication ID5006303
P698PubMed publication ID26136391
P5875ResearchGate publication ID279729102

P50authorAndrew GuyQ56561942
James BeesonQ56780488
Ivo MuellerQ60043791
Peter M SibaQ89223280
Paul A. RamslandQ38317548
P2093author name stringJack S Richards
Vashti Irani
P2860cites workLocalization of the 175-kilodalton erythrocyte binding antigen in micronemes of Plasmodium falciparum merozoitesQ68097055
Immune effector mechanisms in malariaQ82383609
Acquired immunity to malariaQ24651173
A Plasmodium falciparum antigen that binds to host erythrocytes and merozoitesQ27230065
Structural and Functional Basis for Inhibition of Erythrocyte Invasion by Antibodies that Target Plasmodium falciparum EBA-175Q27678372
Intramembrane proteolysis mediates shedding of a key adhesin during erythrocyte invasion by the malaria parasiteQ30043432
RH5-Basigin interaction plays a major role in the host tropism of Plasmodium falciparum.Q30356310
Opsonic phagocytosis of Plasmodium falciparum merozoites: mechanism in human immunity and a correlate of protection against malariaQ31169310
A family of erythrocyte binding proteins of malaria parasitesQ33198214
Defining childhood severe falciparum malaria for intervention studiesQ33294896
Safety and immunogenicity of a recombinant nonglycosylated erythrocyte binding antigen 175 Region II malaria vaccine in healthy adults living in an area where malaria is not endemicQ34189972
Estimation of recent and long-term malaria transmission in a population by antibody testing to multiple Plasmodium falciparum antigensQ34209043
Critical glycosylated residues in exon three of erythrocyte glycophorin A engage Plasmodium falciparum EBA-175 and define receptor specificity.Q34237880
An expanding ebl family of Plasmodium falciparumQ34264741
Evidence for erythrocyte-binding antigen 175 as a component of a ligand-blocking blood-stage malaria vaccineQ34937705
Vaccination with conserved regions of erythrocyte-binding antigens induces neutralizing antibodies against multiple strains of Plasmodium falciparumQ34988452
Human antibodies fix complement to inhibit Plasmodium falciparum invasion of erythrocytes and are associated with protection against malariaQ35213495
Measurement of antibody levels against region II of the erythrocyte-binding antigen 175 of Plasmodium falciparum in an area of malaria holoendemicity in western KenyaQ35550197
Antibodies to Plasmodium falciparum erythrocyte-binding antigen-175 are associated with protection from clinical malariaQ35569042
Can growth inhibition assays (GIA) predict blood-stage malaria vaccine efficacy?Q36391845
Identification and prioritization of merozoite antigens as targets of protective human immunity to Plasmodium falciparum malaria for vaccine and biomarker developmentQ36984161
The risk of malarial infections and disease in Papua New Guinean children.Q37088901
Immunoglobulin G subclass-specific responses against Plasmodium falciparum merozoite antigens are associated with control of parasitemia and protection from symptomatic illnessQ37099503
Inhibitory humoral responses to the Plasmodium falciparum vaccine candidate EBA-175 are independent of the erythrocyte invasion pathwayQ37124750
Erythrocyte-binding antigens of Plasmodium falciparum are targets of human inhibitory antibodies and function to evade naturally acquired immunityQ37202344
The future for blood-stage vaccines against malariaQ37471465
Erythrocyte and reticulocyte binding-like proteins of Plasmodium falciparumQ37969486
Case definitions of clinical malaria under different transmission conditions in Kilifi District, KenyaQ39130334
Human antibodies to recombinant protein constructs of Plasmodium falciparum Apical Membrane Antigen 1 (AMA1) and their associations with protection from malariaQ39362569
Antibodies against the Plasmodium falciparum receptor binding domain of EBA-175 block invasion pathways that do not involve sialic acidsQ39515040
A recombinant baculovirus-expressed Plasmodium falciparum receptor-binding domain of erythrocyte binding protein EBA-175 biologically mimics native protein.Q39516438
Erythrocyte entry by malarial parasites. A moving junction between erythrocyte and parasiteQ39600996
Receptor and ligand domains for invasion of erythrocytes by Plasmodium falciparum.Q41460430
Mechanisms underlying the monocyte-mediated antibody-dependent killing of Plasmodium falciparum asexual blood stagesQ41835030
Association between naturally acquired antibodies to erythrocyte-binding antigens of Plasmodium falciparum and protection from malaria and high-density parasitemiaQ47954510
Structural basis for the EBA-175 erythrocyte invasion pathway of the malaria parasite Plasmodium falciparumQ48013061
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectmalariaQ12156
antibodyQ79460
Plasmodium falciparumQ311383
Plasmodium falciparum malariaQ18554672
P304page(s)1244-1252
P577publication date2015-07-01
P1433published inClinical Infectious DiseasesQ5133764
P1476titleAcquisition of Functional Antibodies That Block the Binding of Erythrocyte-Binding Antigen 175 and Protection Against Plasmodium falciparum Malaria in Children
P478volume61

Reverse relations

cites work (P2860)
Q40102134Acquisition, maintenance and adaptation of invasion inhibitory antibodies against Plasmodium falciparum invasion ligands involved in immune evasion
Q47347281Assessment of the quality and quantity of naturally induced antibody responses to EBA175RIII–V in Ghanaian children living in two communities with varying malaria transmission patterns
Q47602559Beyond binding: antibody effector functions in infectious diseases.
Q91918114Contribution of Functional Antimalarial Immunity to Measures of Parasite Clearance in Therapeutic Efficacy Studies of Artemisinin Derivatives
Q30386145Different Regions of Plasmodium falciparum Erythrocyte-Binding Antigen 175 Induce Antibody Responses to Infection of Varied Efficacy.
Q44482507Editorial Commentary: Toward a Better Malaria Vaccine: Understanding How Antibodies to Malaria Protect Against Disease
Q38650817Genetic evidence for erythrocyte receptor glycophorin B expression levels defining a dominant Plasmodium falciparum invasion pathway into human erythrocytes
Q45944502Identification of immune signatures predictive of clinical protection from malaria.
Q58752517IgG subclass responses to excreted-secreted antigens of Plasmodium falciparum in a low-transmission malaria area of the Peruvian Amazon
Q26772878Merozoite surface proteins in red blood cell invasion, immunity and vaccines against malaria
Q37647647Naturally Acquired Binding-Inhibitory Antibodies to Plasmodium vivax Duffy Binding Protein in Pregnant Women Are Associated with Higher Birth Weight in a Multicenter Study
Q54257311Proteome-wide mapping of immune features onto Plasmodium protein three-dimensional structures.
Q30248811Recent insights into humoral immunity targeting Plasmodium falciparum and Plasmodium vivax malaria
Q37265801Safety and immunogenicity of EBA-175 RII-NG Malaria vaccine administered intramuscularly in semi-immune adults: A Phase 1, Double-blinded placebo controlled dosage escalation study

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