| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2000PNAS...97.8461G |
| P356 | DOI | 10.1073/PNAS.97.15.8461 |
| P932 | PMC publication ID | 26970 |
| P698 | PubMed publication ID | 10900007 |
| P5875 | ResearchGate publication ID | 12419278 |
| P50 | author | Toshinori Nakayama | Q37834721 |
| Moriya Tsuji | Q37842009 | ||
| Oscar Bruna-Romero | Q40687756 | ||
| Camila Indiani de Oliveira | Q56451373 | ||
| P2093 | author name string | Y Koezuka | |
| M Taniguchi | |||
| S Hong | |||
| A Bendelac | |||
| L Van Kaer | |||
| G Gonzalez-Aseguinolaza | |||
| M Tomaska | |||
| P2860 | cites work | Binding and antigen presentation of ceramide-containing glycolipids by soluble mouse and human CD1d molecules | Q22010665 |
| CD8(+)NKR-P1A (+)T cells preferentially accumulate in human liver | Q28142807 | ||
| CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides | Q28254991 | ||
| CD1 recognition by mouse NK1+ T lymphocytes | Q28591238 | ||
| CD1d1 mutant mice are deficient in natural T cells that promptly produce IL-4 | Q28594577 | ||
| Lipid antigen presentation in the immune system: lessons learned from CD1d knockout mice. | Q33713269 | ||
| IL-12 and NK cells are required for antigen-specific adaptive immunity against malaria initiated by CD8+ T cells in the Plasmodium yoelii model | Q33867200 | ||
| Gamma delta T cells contribute to immunity against the liver stages of malaria in alpha beta T-cell-deficient mice | Q34957552 | ||
| Murine natural killer T(NKT) cells [correction of natural killer cells] contribute to the granulomatous reaction caused by mycobacterial cell walls | Q36338528 | ||
| CD4+ cytolytic T cell clone confers protection against murine malaria | Q36353821 | ||
| An invariant T cell receptor alpha chain is used by a unique subset of major histocompatibility complex class I-specific CD4+ and CD4-8- T cells in mice and humans. | Q36363643 | ||
| A role for CD4+ NK1.1+ T lymphocytes as major histocompatibility complex class II independent helper cells in the generation of CD8+ effector function against intracellular infection | Q36366985 | ||
| alpha/beta-T cell receptor (TCR)+CD4-CD8- (NKT) thymocytes prevent insulin-dependent diabetes mellitus in nonobese diabetic (NOD)/Lt mice by the influence of interleukin (IL)-4 and/or IL-10. | Q36400534 | ||
| Overexpression of natural killer T cells protects Valpha14- Jalpha281 transgenic nonobese diabetic mice against diabetes. | Q36401271 | ||
| CD1d-restricted recognition of synthetic glycolipid antigens by human natural killer T cells | Q36404272 | ||
| Mouse NK1.1+ T cells: a new family of T cells | Q36819827 | ||
| Primaquine resistance in Plasmodium vivax | Q38950998 | ||
| Mouse NK1+ T cells | Q40404876 | ||
| T cell responses to pre-erythrocytic stages of malaria: role in protection and vaccine development against pre-erythrocytic stages | Q40898245 | ||
| Selective ability of mouse CD1 to present glycolipids: alpha-galactosylceramide specifically stimulates V alpha 14+ NK T lymphocytes. | Q41005207 | ||
| Mouse CD1-specific NK1 T cells: development, specificity, and function | Q41464349 | ||
| Drug resistant Plasmodium vivax malaria | Q41927164 | ||
| Sterile protection of monkeys against malaria after administration of interleukin-12. | Q43923494 | ||
| The large difference in infectivity for mice of Plasmodium berghei and Plasmodium yoelii sporozoites cannot be correlated with their ability to enter into hepatocytes | Q44173638 | ||
| Acute rejection of marrow grafts in mice. Dependence on and independence of functional TCR in the rejection process | Q46968133 | ||
| Liver CD4-CD8- NK1.1+ TCR alpha beta intermediate cells increase during experimental malaria infection and are able to exhibit inhibitory activity against the parasite liver stage in vitro. | Q47858000 | ||
| Inhibition of development of exoerythrocytic forms of malaria parasites by gamma-interferon | Q47907672 | ||
| Quantification of antigen specific CD8+ T cells using an ELISPOT assay | Q47999428 | ||
| Impaired NK1+ T cell development and early IL-4 production in CD1-deficient mice. | Q52525223 | ||
| IL-4 secretion by CD4+ NK1+ T cells induces monocyte chemoattractant protein-1 in early listeriosis. | Q52526044 | ||
| Cutting edge: anti-CD1 monoclonal antibody treatment reverses the production patterns of TGF-beta 2 and Th1 cytokines and ameliorates listeriosis in mice. | Q52978784 | ||
| Induction of IFN-gamma-producing CD4+ natural killer T cells by Mycobacterium bovis bacillus Calmette Guérin. | Q52980196 | ||
| Rapid Death and Regeneration of NKT Cells in Anti-CD3ε- or IL-12-Treated Mice | Q59387573 | ||
| Isolation and flow cytometric analysis of the free lymphomyeloid cells present in murine liver | Q68536782 | ||
| Selective reduction of V alpha 14+ NK T cells associated with disease development in autoimmune-prone mice | Q71059498 | ||
| IL-12-deficient mice are defective in IFN gamma production and type 1 cytokine responses | Q71079171 | ||
| KRN7000, a novel immunomodulator, and its antitumor activities | Q71674742 | ||
| Cutting edge: Cross-talk between cells of the innate immune system: NKT cells rapidly activate NK cells | Q73098737 | ||
| Requirement for Valpha14 NKT cells in IL-12-mediated rejection of tumors | Q73889862 | ||
| Treatment of hepatic metastasis of the colon26 adenocarcinoma with an alpha-galactosylceramide, KRN7000 | Q74356047 | ||
| Syntheses of biotinylated alpha-galactosylceramides and their effects on the immune system and CD1 molecules | Q77807457 | ||
| P433 | issue | 15 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | malaria | Q12156 |
| P304 | page(s) | 8461-8466 | |
| P577 | publication date | 2000-07-01 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | alpha -galactosylceramide-activated Valpha 14 natural killer T cells mediate protection against murine malaria | |
| P478 | volume | 97 |
| Q33748552 | A comprehensive ex vivo functional analysis of human NKT cells reveals production of MIP1-α and MIP1-β, a lack of IL-17, and a Th1-bias in males |
| Q37644961 | A double-edged sword: the role of NKT cells in malaria and HIV infection and immunity |
| Q27303293 | A glycolipid adjuvant, 7DW8-5, enhances CD8+ T cell responses induced by an adenovirus-vectored malaria vaccine in non-human primates |
| Q33570532 | A multifactorial mechanism in the superior antimalarial activity of alpha-C-GalCer |
| Q36625367 | A review of human vaccine research and development: malaria |
| Q45403297 | A single intranasal immunization with inactivated influenza virus and alpha-galactosylceramide induces long-term protective immunity without redirecting antigen to the central nervous system |
| Q36403849 | A subset of liver NK T cells is activated during Leishmania donovani infection by CD1d-bound lipophosphoglycan |
| Q41813943 | AIM inhibits apoptosis of T cells and NKT cells in Corynebacterium-induced granuloma formation in mice |
| Q34182581 | Activation of NKT cells protects mice from tuberculosis. |
| Q39517775 | Activation of Valpha14(+) natural killer T cells by alpha-galactosylceramide results in development of Th1 response and local host resistance in mice infected with Cryptococcus neoformans |
| Q27318814 | Activation of invariant NKT cells exacerbates experimental visceral leishmaniasis |
| Q34467874 | Activation of natural killer (NK) T cells during murine cytomegalovirus infection enhances the antiviral response mediated by NK cells |
| Q34714252 | Activation of natural killer T cells by alpha-galactosylceramide impairs DNA vaccine-induced protective immunity against Trypanosoma cruzi |
| Q36371349 | Activation of natural killer T cells by alpha-galactosylceramide rapidly induces the full maturation of dendritic cells in vivo and thereby acts as an adjuvant for combined CD4 and CD8 T cell immunity to a coadministered protein |
| Q41969156 | Adjuvants of immunity: harnessing innate immunity to promote adaptive immunity |
| Q43759628 | Alpha versus beta: are we on the way to resolve the mystery as to which is the endogenous ligand for natural killer T cells? |
| Q34172161 | Alpha-galactosylceramide as a therapeutic agent for pulmonary Mycobacterium tuberculosis infection |
| Q33877217 | Alpha-galactosylceramide promotes killing of Listeria monocytogenes within the macrophage phagosome through invariant NKT-cell activation |
| Q38896926 | Analysis of invariant natural killer T cells in human paracoccidioidomycosis. |
| Q37499317 | Antigen Presentation by CD1 Lipids, T Cells, and NKT Cells in Microbial Immunity |
| Q36994245 | Antimalarial activity of axidjiferosides, new β-galactosylceramides from the African sponge Axinyssa djiferi |
| Q36432420 | Antiplasmodial marine natural products in the perspective of current chemotherapy and prevention of malaria: a review |
| Q28208367 | Autoreactivity by design: innate B and T lymphocytes |
| Q36095320 | Biosynthesis and immunogenicity of glucosylceramide in Cryptococcus neoformans and other human pathogens |
| Q36369438 | CD1-restricted NK T cells protect nonobese diabetic mice from developing diabetes |
| Q34332693 | CD1-specific T cells in microbial immunity |
| Q74221432 | CD1d-dependent macrophage-mediated clearance of Pseudomonas aeruginosa from lung |
| Q35798159 | CD1d-restricted T-cell subsets and dendritic cell function in autoimmunity |
| Q39006369 | CD1d-restricted natural killer T cells are potent targets for human immunodeficiency virus infection |
| Q45150866 | CD4(+) and CD4(-) CD1D-restricted natural killer T cells in perinatally HIV-1 infected children receiving highly active antiretroviral therapy |
| Q37118132 | Carbohydrates and T cells: a sweet twosome |
| Q37846879 | Cell biology and immunology of malaria |
| Q36953474 | Chronic restraint stress reduces carbon tetrachloride-induced liver fibrosis |
| Q44151205 | Circulating concentrations of soluble granzyme A and B increase during natural and experimental Plasmodium falciparum infections |
| Q37824065 | Clinical development of a novel CD1d-binding NKT cell ligand as a vaccine adjuvant |
| Q37534468 | Contribution of the Ly49E natural killer receptor in the immune response to Plasmodium berghei infection and control of hepatic parasite development |
| Q34402230 | CpG oligodeoxynucleotides stimulate protective innate immunity against pulmonary Klebsiella infection |
| Q36371566 | Cutaneous immunization rapidly activates liver invariant Valpha14 NKT cells stimulating B-1 B cells to initiate T cell recruitment for elicitation of contact sensitivity |
| Q36097274 | Cyclic di-GMP stimulates protective innate immunity in bacterial pneumonia |
| Q40680313 | Detection and activation of human Valpha24+ natural killer T cells using alpha-galactosyl ceramide-pulsed dendritic cells |
| Q46272151 | Development of a Novel CD4+ TCR Transgenic Line That Reveals a Dominant Role for CD8+ Dendritic Cells and CD40 Signaling in the Generation of Helper and CTL Responses to Blood-Stage Malaria |
| Q55293243 | Development of a novel mechanism-based glycolipid adjuvant for vaccination. |
| Q41858795 | Direct CD1d-mediated stimulation of APC IL-12 production and protective immune response to virus infection in vivo. |
| Q60692472 | Direct and Efficient Glycosylation Protocol for Synthesizing α-Glycolipids: Application to the Synthesis of KRN7000 |
| Q33731430 | Distinct requirements for CD1d intracellular transport for development of V(alpha)14 iNKT cells |
| Q34115997 | During Trypanosoma cruzi infection CD1d-restricted NK T cells limit parasitemia and augment the antibody response to a glycophosphoinositol-modified surface protein |
| Q58845163 | During acute Trypanosoma cruzi infection highly susceptible mice deficient in natural killer cells are protected by a single alpha-galactosylceramide treatment |
| Q44825308 | Electric foot shock stress-induced exacerbation of alpha-galactosylceramide-triggered apoptosis in mouse liver. |
| Q33552034 | Enhanced gamma interferon production through activation of Valpha14(+) natural killer T cells by alpha-galactosylceramide in interleukin-18-deficient mice with systemic cryptococcosis |
| Q36478707 | Estimation of heterogeneity in malaria transmission by stochastic modelling of apparent deviations from mass action kinetics |
| Q37582319 | Exacerbation of invasive Candida albicans infection by commensal bacteria or a glycolipid through IFN-γ produced in part by iNKT cells. |
| Q36278752 | Exploiting the innate immune system to control allergic asthma |
| Q79619313 | Functional alterations of liver innate immunity of mice with aging in response to CpG-oligodeoxynucleotide |
| Q36370359 | Functionally distinct subsets of CD1d-restricted natural killer T cells revealed by CD1d tetramer staining |
| Q55318324 | Functions of CD1d-Restricted Invariant Natural Killer T Cells in Antimicrobial Immunity and Potential Applications for Infection Control. |
| Q45734984 | Generation of cellular immunity to lymphocytic choriomeningitis virus is independent of CD1d1 expression. |
| Q35798141 | Genetic control of NKT cell numbers |
| Q37520646 | Glucocerebroside: an evolutionary advantage for patients with Gaucher disease and a new immunomodulatory agent |
| Q34448496 | Glycolipid targets of CD1-mediated T-cell responses |
| Q35038298 | Hepatic T cells and liver tolerance |
| Q33798041 | Hepatitis C virus infection may lead to slower emergence of P. falciparum in blood |
| Q51780736 | Human CD4+ invariant NKT cells are involved in antibacterial immunity against Brucella suis through CD1d-dependent but CD4-independent mechanisms. |
| Q37462515 | Human cytomegalovirus (HCMV) US2 protein interacts with human CD1d (hCD1d) and down-regulates invariant NKT (iNKT) cell activity |
| Q45372912 | IFN-γ production downstream of NKT cell activation in mice infected with influenza virus enhances the cytolytic activities of both NK cells and viral antigen-specific CD8+ T cells |
| Q37773306 | Immune adjuvants in early life: targeting the innate immune system to overcome impaired adaptive response |
| Q38946873 | Immune response to Plasmodium vivax has a potential to reduce malaria severity |
| Q34688305 | Immunotherapy with ligands of natural killer T cells |
| Q51875279 | In-vivo stimulation of macaque natural killer T cells with α-galactosylceramide. |
| Q34275397 | Induced pluripotency as a potential path towards iNKT cell-mediated cancer immunotherapy |
| Q34031887 | Inhibition of glycolipid shedding rescues recognition of a CD1+ T cell lymphoma by natural killer T (NKT) cells. |
| Q44665307 | Innate immune response to encephalomyocarditis virus infection mediated by CD1d |
| Q59490101 | Innate immunity modulates autoimmunity: type 1 interferon-beta treatment in multiple sclerosis promotes growth and function of regulatory invariant natural killer T cells through dendritic cell maturation |
| Q73862262 | Interleukin-12 and interleukin-2-induced invariant natural killer T-cell cytokine secretion and perforin expression independent of T-cell receptor activation |
| Q34006411 | Interleukin-12- and gamma interferon-dependent protection against malaria conferred by CpG oligodeoxynucleotide in mice |
| Q37405955 | Intracellular bacterial infection and invariant NKT cells |
| Q36251325 | Intradermal NKT cell activation during DNA priming in heterologous prime-boost vaccination enhances T cell responses and protection against Leishmania |
| Q40190734 | Intrahepatic delivery of alpha-galactosylceramide-pulsed dendritic cells suppresses liver tumor |
| Q37822744 | Invariant NK T cells: potential for immunotherapeutic targeting with glycolipid antigens |
| Q30479030 | Invariant NKT cells sustain specific B cell responses and memory |
| Q33792633 | Invariant Valpha14 chain NKT cells promote Plasmodium berghei circumsporozoite protein-specific gamma interferon- and tumor necrosis factor alpha-producing CD8+ T cells in the liver after poxvirus vaccination of mice |
| Q38883497 | Invariant natural killer T cells: front line fighters in the war against pathogenic microbes |
| Q34449017 | Liver-inherent immune system: its role in blood-stage malaria |
| Q52595183 | Macrophage Transactivation for Chemokine Production Identified as a Negative Regulator of Granulomatous Inflammation Using Agent-Based Modeling. |
| Q44131983 | Mesenchymal stem cells play an important role in host protective immune responses against malaria by modulating regulatory T cells |
| Q53971098 | Minimal contribution of Valpha14 natural killer T cells to Th1 response and host resistance against mycobacterial infection in mice. |
| Q36632492 | Modulation of invariant natural killer T cell cytokine responses by indoleamine 2,3-dioxygenase |
| Q46414672 | NK cell activation and protection occur independently of natural killer T cells during Trypanosoma cruzi infection |
| Q33352690 | NK cell-like behavior of Valpha14i NK T cells during MCMV infection |
| Q35798179 | NKT cells and viral immunity |
| Q83185408 | NKT cells play critical roles in the induction of oral tolerance by inducing regulatory T cells producing IL-10 and transforming growth factor beta, and by clonally deleting antigen-specific T cells |
| Q47873122 | NKT cells protect against pre-erythocytic malaria |
| Q34091324 | NKT cells: facts, functions and fallacies. |
| Q36370322 | Natural killer T cell ligand alpha-galactosylceramide enhances protective immunity induced by malaria vaccines |
| Q33444653 | Natural killer T cells activated by a lipopeptidophosphoglycan from Entamoeba histolytica are critically important to control amebic liver abscess |
| Q34605137 | Natural killer T cells: an unconventional T-cell subset with diverse effector and regulatory functions. |
| Q36538364 | Participatory role of natural killer and natural killer T cells in atherosclerosis: lessons learned from in vivo mouse studies |
| Q34461021 | Peripheral blood invariant natural killer T cells of pig-tailed macaques |
| Q28081143 | Plasmodium cellular effector mechanisms and the hepatic microenvironment |
| Q34129309 | Presentation of self and microbial lipids by CD1 molecules |
| Q35784187 | Primary infection of C57BL/6 mice with Plasmodium yoelii induces a heterogeneous response of NKT cells |
| Q34280935 | Progress toward a malaria vaccine: efficient induction of protective anti-malaria immunity |
| Q53963043 | Prolonged IFN-gamma-producing NKT response induced with alpha-galactosylceramide-loaded DCs. |
| Q28068626 | Protective immunity to liver-stage malaria |
| Q37530782 | Psychosocial stress and liver disease status. |
| Q27320844 | Relationships between Th1 or Th2 iNKT cell activity and structures of CD1d-antigen complexes: meta-analysis of CD1d-glycolipids dynamics simulations |
| Q24294851 | Role of CD1d-restricted NKT cells in microbial immunity |
| Q47917742 | Role of NKT cells and alpha-galactosyl ceramide |
| Q39166479 | Role of dendritic cell maturation factors produced by human invariant NKT cells in immune tolerance |
| Q33848840 | Selective loss of natural killer T cells by apoptosis following infection with lymphocytic choriomeningitis virus. |
| Q36300615 | Structural features of the acyl chain determine self-phospholipid antigen recognition by a CD1d-restricted invariant NKT (iNKT) cell |
| Q36371546 | Superior protection against malaria and melanoma metastases by a C-glycoside analogue of the natural killer T cell ligand alpha-Galactosylceramide |
| Q40908607 | Synthesis of C-5″ and C-6″-modified α-GalCer analogues as iNKT-cell agonists |
| Q35066264 | T cells as mediators of protective immunity against liver stages of Plasmodium |
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| Q41911304 | The NKG2D-activating receptor mediates pulmonary clearance of Pseudomonas aeruginosa |
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| Q36371045 | The TLR2 is activated by sporozoites and suppresses intrahepatic rodent malaria parasite development. |
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| Q47941762 | The age-related resistance of rats to Plasmodium berghei infection is associated with differential cellular and humoral immune responses |
| Q39192254 | The combination therapy of α-galactosylceramide and 5-fluorouracil showed antitumor effect synergistically against liver tumor in mice. |
| Q34469793 | The involvement of class Ib molecules in the host response to infection with Salmonella and its relevance to autoimmunity |
| Q43678244 | The physical properties of glycosyl diacylglycerols. Calorimetric, X-ray diffraction and Fourier transform spectroscopic studies of a homologous series of 1,2-di-O-acyl-3-O-(beta-D-galactopyranosyl)-sn-glycerols |
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| Q37621786 | The specialized iNKT cell system recognizes glycolipid antigens and bridges the innate and acquired immune systems with potential applications for cancer therapy |
| Q33843406 | The stimulating adventure of KRN 7000. |
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| Q52005428 | Therapeutic activation of Vα24+Vβ11+ NKT cells in human subjects results in highly coordinated secondary activation of acquired and innate immunity |
| Q40338086 | Therapeutic effect of alpha-galactosylceramide-loaded dendritic cells genetically engineered to express SLC/CCL21 along with tumor antigen against peritoneally disseminated tumor cells |
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| Q36354705 | V alpha14 i NKT cells are innate lymphocytes that participate in the immune response to diverse microbes |
| Q37150329 | Various carrier system(s)- mediated genetic vaccination strategies against malaria |
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