scholarly article | Q13442814 |
P819 | ADS bibcode | 2000PNAS...97.8490W |
P356 | DOI | 10.1073/PNAS.150104097 |
P932 | PMC publication ID | 26975 |
P698 | PubMed publication ID | 10890910 |
P5875 | ResearchGate publication ID | 12428080 |
P2093 | author name string | T Watanabe | |
B A Sullenger | |||
P2860 | cites work | Gain of function mutations in p53. | Q41557652 |
Modulation of activity of the promoter of the human MDR1 gene by Ras and p53. | Q41643433 | ||
Genetic mechanisms of tumor suppression by the human p53 gene | Q41710706 | ||
Tagging ribozyme reaction sites to follow trans-splicing in mammalian cells | Q42812813 | ||
Ribozyme-mediated repair of sickle beta-globin mRNAs in erythrocyte precursors | Q45887644 | ||
Trans -splicing ribozymes for targeted gene delivery 1 1Edited by J. Karn | Q57902856 | ||
Wild-type p53 activates transcription in vitro | Q59054260 | ||
Cotranslation of activated mutant p53 with wild type drives the wild-type p53 protein into the mutant conformation | Q70168032 | ||
The dominating effect of mutant p53 | Q72293557 | ||
A mutant p53 transgene accelerates tumour development in heterozygous but not nullizygous p53-deficient mice | Q72293593 | ||
Probing the interplay between the two steps of group I intron splicing: competition of exogenous guanosine with omega G | Q77917378 | ||
Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations | Q27730815 | ||
WAF1, a potential mediator of p53 tumor suppression | Q27861121 | ||
Definition of a consensus binding site for p53 | Q28207794 | ||
Oncogenic forms of p53 inhibit p53-regulated gene expression | Q28251120 | ||
Identification of p53 as a sequence-specific DNA-binding protein | Q28282745 | ||
p53 mutations in human cancers | Q28302973 | ||
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene | Q28306186 | ||
Suppression of human colorectal carcinoma cell growth by wild-type p53 | Q29618318 | ||
Self-splicing of the Tetrahymena intron from mRNA in mammalian cells | Q30304459 | ||
One binding site determines sequence specificity of Tetrahymena pre-rRNA self-splicing, trans-splicing, and RNA enzyme activity | Q30461490 | ||
Intermolecular exon ligation of the rRNA precursor of Tetrahymena: oligonucleotides can function as 5' exons | Q30463369 | ||
Identification of ribozymes within a ribozyme library that efficiently cleave a long substrate RNA. | Q30463740 | ||
Ribozyme-mediated repair of defective mRNA by targeted, trans-splicing | Q30465698 | ||
p53 tumor suppressor gene therapy for cancer. | Q33768194 | ||
Rearrangement of the p53 gene in human osteogenic sarcomas | Q34360802 | ||
Adenovirus-mediated gene transfer of the tumor suppressor, p53, induces apoptosis in postmitotic neurons | Q36256866 | ||
The biochemistry of P-glycoprotein-mediated multidrug resistance | Q38364215 | ||
Ribozyme-mediated trans-splicing of a trinucleotide repeat. | Q41051948 | ||
P433 | issue | 15 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | ribozyme | Q205858 |
P304 | page(s) | 8490-8494 | |
P577 | publication date | 2000-07-01 | |
P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
P1476 | title | Induction of wild-type p53 activity in human cancer cells by ribozymes that repair mutant p53 transcripts | |
P478 | volume | 97 |
Q34365389 | 5' exon replacement and repair by spliceosome-mediated RNA trans-splicing |
Q59091650 | Achilles' heel of cancer? |
Q34119859 | Advances in gene therapy for malignant melanoma |
Q35597089 | Approaches for the sequence-specific knockdown of mRNA. |
Q34580489 | Cancer chemoresistance: the relationship between p53 and multidrug transporters |
Q35775827 | Computational prediction of efficient splice sites for trans-splicing ribozymes |
Q34733424 | Defects in G1-S cell cycle control in head and neck cancer: a review |
Q54604030 | Detection of mRNA in mammalian cells with a split ribozyme reporter. |
Q90666977 | Diverse Mechanisms of RNA Recombination |
Q33923881 | Effective suppression of dengue virus using a novel group-I intron that induces apoptotic cell death upon infection through conditional expression of the Bax C-terminal domain |
Q34365376 | Efficient and specific repair of sickle beta-globin RNA by trans-splicing ribozymes |
Q28214164 | Emerging clinical applications of RNA |
Q35549357 | Engineered Ribozymes as Molecular Tools for Site‐Specific Alteration of RNA Sequence |
Q47784889 | Exploiting differential RNA splicing patterns: a potential new group of therapeutic targets in cancer |
Q34417562 | Exploiting genetic alterations to design novel therapies for cancer |
Q39740174 | Functional repair of a mutant chloride channel using a trans-splicing ribozyme |
Q24792778 | Gene Therapy for Pediatric Cancer: State of the Art and Future Perspectives |
Q79117427 | Gene therapy for lung cancer |
Q24794819 | Group I aptazymes as genetic regulatory switches |
Q44420167 | Hammerhead ribozyme-mediated destruction of nuclear foci in myotonic dystrophy myoblasts |
Q34387772 | Imaging Tetrahymena ribozyme splicing activity in single live mammalian cells |
Q40093470 | In vivo reprogramming of hTERT by trans-splicing ribozyme to target tumor cells |
Q79266288 | In-cell generation of antibody single-chain Fv transcripts by targeted RNA trans-splicing |
Q37571729 | Irinotecan therapy and molecular targets in colorectal cancer: a systemic review |
Q37311367 | Low selection pressure aids the evolution of cooperative ribozyme mutations in cells |
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Q35202462 | Messenger RNA reprogramming by spliceosome-mediated RNA trans-splicing |
Q37180948 | Molecular approaches to sarcoma therapy |
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Q34276988 | Mutations in apoptosis genes: a pathogenetic factor for human disease |
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Q34079549 | RNA repair: a novel approach to gene therapy |
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Q28199928 | The molecular biology of cancer |
Q36921977 | The molecular underpinnings of genetic phenomena |
Q37417135 | The structure and function of catalytic RNAs |
Q37081504 | The use of p53 as a tool for human cancer therapy |
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