Kinetic analysis of a mammalian phospholipase D: allosteric modulation by monomeric GTPases, protein kinase C, and polyphosphoinositides

scientific article published on 08 December 2005

Kinetic analysis of a mammalian phospholipase D: allosteric modulation by monomeric GTPases, protein kinase C, and polyphosphoinositides is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M508800200
P932PMC publication ID3800466
P698PubMed publication ID16339153

P2093author name stringH Alex Brown
John H Exton
Lee G Henage
P2860cites workARAP1: a point of convergence for Arf and Rho signalingQ24292200
Evidence for ADP-ribosylation-factor-mediated activation of phospholipase D by m3 muscarinic acetylcholine receptorQ24311714
Determination of interaction sites of phospholipase D1 for RhoAQ24532779
A novel family of phospholipase D homologues that includes phospholipid synthases and putative endonucleases: identification of duplicated repeats and potential active site residuesQ24674165
Molecular diversity of phospholipase D in angiospermsQ24803089
Crystal structure of a phospholipase D family memberQ27617507
Activation of phospholipase D1 by Cdc42 requires the Rho insert regionQ28140512
Phosphatidylinositol 4,5-bisphosphate provides an alternative to guanine nucleotide exchange factors by stimulating the dissociation of GDP from Cdc42HsQ71514875
Novel function of phosphatidylinositol 4,5-bisphosphate as a cofactor for brain membrane phospholipase DQ72135980
Resolved phospholipase D activity is modulated by cytosolic factors other than ArfQ72350327
Effects of acid phospholipids on nucleotide exchange properties of ADP-ribosylation factor 1. Evidence for specific interaction with phosphatidylinositol 4,5-bisphosphateQ72808716
Mammalian Cdc42 is a brefeldin A-sensitive component of the Golgi apparatusQ95826484
Phospholipase D in cell proliferation and cancerQ28205631
Phospholipase D-structure, regulation and functionQ28216408
Golgi-localized GAP for Cdc42 functions downstream of ARF1 to control Arp2/3 complex and F-actin dynamicsQ28241896
Phospholipase DQ28253553
Characterization of two alternately spliced forms of phospholipase D1. Activation of the purified enzymes by phosphatidylinositol 4,5-bisphosphate, ADP-ribosylation factor, and Rho family monomeric GTP-binding proteins and protein kinase C-alphaQ28302448
ADP ribosylation factor 6 binding to phosphatidylinositol 4,5-bisphosphate-containing vesicles creates defects in the bilayer structure: an electron spin resonance studyQ28344526
Phosphohydrolase and transphosphatidylation reactions of two Streptomyces phospholipase D enzymes: covalent versus noncovalent catalysisQ30819575
The PLD superfamily: insights into catalysisQ33698805
Requirement of phospholipase D1 activity in H-RasV12-induced transformationQ33817312
Mutagenesis of phospholipase D defines a superfamily including a trans-Golgi viral protein required for poxvirus pathogenicity.Q33887155
Phospholipase D is present on Golgi-enriched membranes and its activation by ADP ribosylation factor is sensitive to brefeldin AQ34277362
Dual requirement for rho and protein kinase C in direct activation of phospholipase D1 through G protein-coupled receptor signalingQ34785463
The role of phosphatidic acid in the regulation of the Ras/MEK/Erk signaling cascadeQ34980709
Measurement of G Protein-Coupled Receptor-Stimulated Phospholipase D Activity in Intact CellsQ35538886
Phosphoinositides in constitutive membrane traffic.Q35842974
Regulation and cellular roles of phosphoinositide 5-kinasesQ35908502
Regulation of phospholipase D1 subcellular cycling through coordination of multiple membrane association motifs.Q36323228
Mammalian phospholipase D: phosphatidylethanolamine as an essential componentQ37635541
Definition of the protein kinase C interaction site of phospholipase D.Q38339136
Protein-DNA interactions at a drug-responsive element of the human apolipoprotein A-I geneQ38352112
Lipid Signaling Enzymes and Surface Dilution KineticsQ40464125
Assays and characterization of mammalian phosphatidylinositol 4,5-bisphosphate-sensitive phospholipase D.Q40773595
Potent direct inhibition of mammalian phospholipase D isoenzymes by calphostin-cQ40809457
Influence of phosphatidylinositol 4,5-bisphosphate on human phospholipase D1 wild-type and deletion mutants: is there evidence for an interaction of phosphatidylinositol 4,5-bisphosphate with the putative pleckstrin homology domain?Q40858588
Phospholipase D regulation and localisation is dependent upon a phosphatidylinositol 4,5-biphosphate-specific PH domainQ40902073
Identification of a phosphoinositide binding motif that mediates activation of mammalian and yeast phospholipase D isoenzymesQ40920316
Protein kinase C bound to the Golgi apparatus supports the formation of constitutive transport vesiclesQ41148053
ADP-ribosylation factor, a small GTP-dependent regulatory protein, stimulates phospholipase D activityQ41508317
Characterization of a rat brain phospholipase D isozymeQ42060848
Structural analysis of human phospholipase D1.Q42467091
Association of Cdc42/N-WASP/Arp2/3 signaling pathway with Golgi membranesQ42824631
Mechanism of protein kinase C activation by phosphatidylinositol 4,5-bisphosphateQ43789783
Specificity of Rho insert-mediated activation of phospholipase D1.Q43993768
Kinetic analysis of Arabidopsis phospholipase Ddelta. Substrate preference and mechanism of activation by Ca2+ and phosphatidylinositol 4,5-biphosphateQ44192029
The reaction mechanism of phospholipase D from Streptomyces sp. strain PMF. Snapshots along the reaction pathway reveal a pentacoordinate reaction intermediate and an unexpected final product.Q44912634
Mechanism of membrane binding of the phospholipase D1 PX domainQ45099229
Localization and regulation of phospholipase D2 by ARF6.Q46368807
Identification of interaction sites of protein kinase Calpha on phospholipase D1.Q46541774
Ultracentrifugation technique for measuring the binding of peptides and proteins to sucrose-loaded phospholipid vesiclesQ47834878
Cloning and characterization of phospholipase D from rat brainQ48042634
Kinetic analysis in mixed micelles of partially purified rat brain phospholipase D activity and its activation by phosphatidylinositol 4,5-bisphosphate.Q48480030
Regulation of phospholipase D by protein kinase C is synergistic with ADP-ribosylation factor and independent of protein kinase activityQ49112664
Activation of plant phospholipase Dbeta by phosphatidylinositol 4,5-bisphosphate: characterization of binding site and mode of action.Q52595159
Nomenclature Committee of the International Union of Biochemistry (NC-IUB). Symbolism and terminology in enzyme kinetics. Recommendations 1981Q70540510
Stimulation of phospholipase D by ADP-ribosylation factorQ70957411
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)3408-3417
P577publication date2005-12-08
P1433published inJournal of Biological ChemistryQ867727
P1476titleKinetic analysis of a mammalian phospholipase D: allosteric modulation by monomeric GTPases, protein kinase C, and polyphosphoinositides
P478volume281

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