Effect of a high-calorie, high-fat meal on the bioavailability and pharmacokinetics of PA-824 in healthy adult subjects

scientific article published on 26 August 2013

Effect of a high-calorie, high-fat meal on the bioavailability and pharmacokinetics of PA-824 in healthy adult subjects is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/AAC.00798-13
P932PMC publication ID3811266
P698PubMed publication ID23979737

P50authorNgozi EronduQ94373328
P2093author name stringAnn Ginsberg
Elliott Pauli
Erica Egizi
Helen Winter
Daniel Everitt
Karl Whitney
P2860cites work14-day bactericidal activity of PA-824, bedaquiline, pyrazinamide, and moxifloxacin combinations: a randomised trialQ39580496
Safety, tolerability, and pharmacokinetics of PA-824 in healthy subjectsQ24641829
PA-824 kills nonreplicating Mycobacterium tuberculosis by intracellular NO releaseQ24654913
A small-molecule nitroimidazopyran drug candidate for the treatment of tuberculosisQ28139874
Preclinical testing of the nitroimidazopyran PA-824 for activity against Mycobacterium tuberculosis in a series of in vitro and in vivo modelsQ33836720
Early bactericidal activity and pharmacokinetics of PA-824 in smear-positive tuberculosis patientsQ34045233
Phase II dose-ranging trial of the early bactericidal activity of PA-824Q36018781
Powerful bactericidal and sterilizing activity of a regimen containing PA-824, moxifloxacin, and pyrazinamide in a murine model of tuberculosisQ36538719
Assessment of the effects of the nitroimidazo-oxazine PA-824 on renal function in healthy subjectsQ37333140
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectpharmacokineticsQ323936
bioavailabilityQ461809
P304page(s)5516-5520
P577publication date2013-08-26
P1433published inAntimicrobial Agents and ChemotherapyQ578004
P1476titleEffect of a high-calorie, high-fat meal on the bioavailability and pharmacokinetics of PA-824 in healthy adult subjects
P478volume57

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Q90387913Modeling and Simulation of Pretomanid Pharmacodynamics in Pulmonary Tuberculosis Patients
Q52584725Modeling and Simulation of Pretomanid Pharmacokinetics in Pulmonary Tuberculosis Patients.
Q104618374Phase 1 Study of the Effects of the Tuberculosis Treatment Pretomanid, Alone and in Combination With Moxifloxacin, on the QTc Interval in Healthy Volunteers
Q92575601Population Pharmacokinetics of the Antituberculosis Agent Pretomanid
Q58606477Tumor-Associated Fibronectin Targeted Liposomal Nanoplatform for Cyclophilin A siRNA Delivery and Targeted Malignant Glioblastoma Therapy

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