| scholarly article | Q13442814 |
| review article | Q7318358 |
| P50 | author | Alexandra M Nicaise | Q85256117 |
| P2093 | author name string | Stephen J Crocker | |
| Ernesto R Bongarzone | |||
| P2860 | cites work | The "quad-partite" synapse: microglia-synapse interactions in the developing and mature CNS | Q26825543 |
| Alternative activation of macrophages | Q27860939 | ||
| Krabbe disease: genetic aspects and progress toward therapy | Q28145439 | ||
| Tenascins: regulation and putative functions during pathological stress | Q28185244 | ||
| Donor-derived cells in the central nervous system of twitcher mice after bone marrow transplantation | Q48110455 | ||
| Tenascin-R and C in multiple sclerosis lesions: relevance to extracellular matrix remodelling | Q48154136 | ||
| Globoid cell leukodystrophy in cairn and West Highland white terriers. | Q48284165 | ||
| Proliferation of microglia/macrophages in the demyelinating CNS and PNS of twitcher mouse. | Q48333212 | ||
| Multinucleated giant cells in brain: a hallmark of the acquired immune deficiency syndrome (AIDS). | Q48387711 | ||
| Microglia/macrophage polarization dynamics reveal novel mechanism of injury expansion after focal cerebral ischemia. | Q48394793 | ||
| Interactions between oligodendrocytes and microglia. A major role for complement and tumour necrosis factor in oligodendrocyte adherence and killing | Q48397929 | ||
| Chemical pathology of Krabbe disease: the occurrence of psychosine and other neutral sphingoglycolipids | Q48418716 | ||
| Cytokine release from microglia: differential inhibition by pentoxifylline and dexamethasone | Q48421414 | ||
| Enzyme replacement with liposomes containing beta-galactosidase from Charonia lumpas in murine globoid cell leukodystrophy (twitcher). | Q48507995 | ||
| Immunohistological study of globoid cell leukodystrophy. | Q48532376 | ||
| Newborn screening for Krabbe disease: the New York State model. | Q48694916 | ||
| Biosynthesis of brain sphingolipids and myelin accumulation in the mouse | Q48723083 | ||
| TNF alpha promotes proliferation of oligodendrocyte progenitors and remyelination. | Q48744723 | ||
| Psychosine cytotoxicity in rat neural cell cultures and protection by phorbol ester and dimethyl sulfoxide. | Q48864840 | ||
| Localization of morphologically distinct microglial populations in the developing human fetal brain: implications for ontogeny. | Q48925081 | ||
| Dynamic changes in pro- and anti-inflammatory cytokines in microglia after PPAR-γ agonist neuroprotective treatment in the MPTPp mouse model of progressive Parkinson's disease | Q61640905 | ||
| The twitcher mouse: fate of exogenously administered [3H]galactosyl-sphingosine | Q70501193 | ||
| Fetal Krabbe leukodystrophy. A morphologic study of two cases | Q70713072 | ||
| Krabbe disease: a galactosylsphingosine (psychosine) lipidosis | Q71133443 | ||
| Hereditary leucodystrophy in the mouse: the new mutant twitcher | Q71327287 | ||
| Pathological and biochemical studies of fetal Krabbe disease | Q72106719 | ||
| Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide | Q72227930 | ||
| Ito cells in lysosomal storage disorders. An ultrastructural study | Q72587627 | ||
| Tissue culture model of Krabbe's disease: psychosine cytotoxicity in rat oligodendrocyte culture | Q73494931 | ||
| Hematopoietic stem-cell transplantation in globoid-cell leukodystrophy | Q74450560 | ||
| A galactolipid possesses novel cancer chemopreventive effects by suppressing inflammatory mediators and mouse B16 melanoma | Q80635905 | ||
| CNS-derived interleukin-4 is essential for the regulation of autoimmune inflammation and induces a state of alternative activation in microglial cells | Q81391451 | ||
| Combined hematopoietic and lentiviral gene-transfer therapies in newborn Twitcher mice reveal contemporaneous neurodegeneration and demyelination in Krabbe disease | Q83276310 | ||
| Death rates in the U.S. due to Krabbe disease and related leukodystrophy and lysosomal storage diseases | Q84995449 | ||
| Does galactocerebrosidase activity predict Krabbe phenotype? | Q87417022 | ||
| Transplantation of umbilical-cord blood in babies with infantile Krabbe's disease | Q28251538 | ||
| Psychosine-induced apoptosis and cytokine activation in immune peripheral cells of Krabbe patients | Q28299387 | ||
| Identification of a unique TGF-β-dependent molecular and functional signature in microglia | Q28303557 | ||
| Molecular cloning and expression of cDNA for murine galactocerebrosidase and mutation analysis of the twitcher mouse, a model of Krabbe's disease | Q28587964 | ||
| The chemokine system in diverse forms of macrophage activation and polarization | Q29547719 | ||
| Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm | Q29614349 | ||
| The M1 and M2 paradigm of macrophage activation: time for reassessment | Q29615845 | ||
| Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord | Q29619388 | ||
| Therapeutic benefit of lentiviral-mediated neonatal intracerebral gene therapy in a mouse model of globoid cell leukodystrophy | Q33649318 | ||
| Globoid cell leucodystrophy (Krabbe's disease): deficiency of galactocerebroside beta-galactosidase | Q33696068 | ||
| Diagnosis of Krabbe's infantile leucodystrophy | Q33735968 | ||
| Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways | Q34035175 | ||
| Proteoglycans in the developing brain: new conceptual insights for old proteins | Q34051689 | ||
| IRF8 is a critical transcription factor for transforming microglia into a reactive phenotype | Q34154359 | ||
| Aberrant production of tenascin-C in globoid cell leukodystrophy alters psychosine-induced microglial functions | Q34214457 | ||
| Galactocerebrosidase-deficient oligodendrocytes maintain stable central myelin by exogenous replacement of the missing enzyme in mice | Q34234577 | ||
| The enzymatic synthesis of psychosine | Q34250213 | ||
| History, genetic, and recent advances on Krabbe disease | Q34440617 | ||
| Environment drives selection and function of enhancers controlling tissue-specific macrophage identities | Q34452301 | ||
| Biochemical and functional characterization of three activated macrophage populations. | Q34556828 | ||
| Classical and alternative activation of mononuclear phagocytes: picking the best of both worlds for tumor promotion | Q34558931 | ||
| Transcription factors in myeloid development: balancing differentiation with transformation. | Q34607145 | ||
| Microglia regulate the number of neural precursor cells in the developing cerebral cortex | Q34649089 | ||
| Transcriptome-based network analysis reveals a spectrum model of human macrophage activation. | Q34659689 | ||
| A neurodegeneration-specific gene-expression signature of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model | Q34746889 | ||
| Central nervous system pathology progresses independently of KC and CXCR2 in globoid-cell leukodystrophy | Q34765786 | ||
| Macrophages counteract demyelination in a mouse model of globoid cell leukodystrophy | Q34912498 | ||
| Psychosine accumulates in membrane microdomains in the brain of krabbe patients, disrupting the raft architecture. | Q34980815 | ||
| Hematopoietic cell transplantation for inherited metabolic diseases: an overview of outcomes and practice guidelines | Q35079584 | ||
| Mechanism-based combination treatment dramatically increases therapeutic efficacy in murine globoid cell leukodystrophy | Q35515608 | ||
| Foreign body-type multinucleated giant cells induced by interleukin-4 express select lymphocyte co-stimulatory molecules and are phenotypically distinct from osteoclasts and dendritic cells | Q35563269 | ||
| Effect of bone marrow transplantation on enzyme levels and clinical course in the neurologically affected twitcher mouse | Q35589620 | ||
| Microglia use multiple mechanisms to mediate interactions with vitronectin; non-essential roles for the highly-expressed αvβ3 and αvβ5 integrins | Q35618230 | ||
| Fibrotic disease and the T(H)1/T(H)2 paradigm | Q35852270 | ||
| Macrophage receptors and immune recognition | Q36072472 | ||
| Characterization of the large deletion in the GALC gene found in patients with Krabbe disease | Q41263648 | ||
| The UDP‐Galactose:Ceramide Galactosyltransferase: Expression Pattern in Oligodendrocytes and Schwann Cells During Myelination and Substrate Preference for Hydroxyceramide | Q41276928 | ||
| A large deletion together with a point mutation in the GALC gene is a common mutant allele in patients with infantile Krabbe disease | Q41320802 | ||
| Formation of multinucleated giant cells and microglial degeneration in rats expressing a mutant Cu/Zn superoxide dismutase gene | Q41832311 | ||
| Intravenous injection of AAVrh10-GALC after the neonatal period in twitcher mice results in significant expression in the central and peripheral nervous systems and improvement of clinical features. | Q42176343 | ||
| Infantile and fetal globoid cell leukodystrophy: analysis of galactosylceramide and galactosylsphingosine | Q42211449 | ||
| Accumulation of galactosylsphingosine (psychosine) in the twitcher mouse: determination by HPLC. | Q42218315 | ||
| Axonopathy is a compounding factor in the pathogenesis of Krabbe disease. | Q43118014 | ||
| Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: granulomatous pathology is shaped by the pattern of L-arginine metabolism | Q43803694 | ||
| Arginase I and polyamines act downstream from cyclic AMP in overcoming inhibition of axonal growth MAG and myelin in vitro. | Q44113660 | ||
| The twitcher mouse: positive immunohistochemical staining of globoid cells with monoclonal antibody against Mac-1 antigen | Q44134226 | ||
| Apoptotic positive cells in Krabbe brain and induction of apoptosis in rat C6 glial cells by psychosine | Q44136654 | ||
| Ultrastructural study of experimental globoid cells. | Q44216176 | ||
| The Hunter's Hope Krabbe family database | Q44555368 | ||
| Later onset phenotypes of Krabbe disease: results of the world-wide registry | Q44832373 | ||
| Galactosylsphingosine galactosyl hydrolase. Partial purification and properties of the enzyme in rat brain | Q45175404 | ||
| Macrophage polarization comes of age. | Q36287066 | ||
| Extended normal life after AAVrh10-mediated gene therapy in the mouse model of Krabbe disease | Q36401067 | ||
| Sphingolipid metabolism diseases | Q36541013 | ||
| Macrophages in inflammatory multiple sclerosis lesions have an intermediate activation status | Q36722852 | ||
| Origin and differentiation of microglia | Q36770859 | ||
| Involvement of perineuronal and perisynaptic extracellular matrix in Alzheimer's disease neuropathology | Q36803086 | ||
| The sphingolipid psychosine inhibits fast axonal transport in Krabbe disease by activation of GSK3β and deregulation of molecular motors | Q36928429 | ||
| Late onset Krabbe's leukodystrophy: a report of four cases | Q36946221 | ||
| Late-Onset Krabbe Disease (Globoid Cell Leukodystrophy): Clinical and Biochemical Features of 15 Cases | Q37048470 | ||
| Missense mutation in mouse GALC mimics human gene defect and offers new insights into Krabbe disease | Q37078839 | ||
| The role of AMPK in psychosine mediated effects on oligodendrocytes and astrocytes: implication for Krabbe disease | Q37171172 | ||
| Brain extracellular matrix in neurodegeneration | Q37228777 | ||
| MMP-3 mediates psychosine-induced globoid cell formation: implications for leukodystrophy pathology | Q37244151 | ||
| Microglial progenitors with a high proliferative potential in the embryonic and adult mouse brain | Q37409060 | ||
| Alternatively activated macrophages in infection and autoimmunity | Q37438259 | ||
| Effects of treatments on inflammatory and apoptotic markers in the CNS of mice with globoid cell leukodystrophy | Q37447171 | ||
| M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination | Q37687158 | ||
| Early microglial colonization of the human forebrain and possible involvement in periventricular white-matter injury of preterm infants | Q37765920 | ||
| Fetal globoid cell leukodystrophy. | Q37871898 | ||
| Repertoire of microglial and macrophage responses after spinal cord injury | Q37889633 | ||
| Review: activation patterns of microglia and their identification in the human brain. | Q38068503 | ||
| Microglia and brain macrophages in the molecular age: from origin to neuropsychiatric disease | Q38203104 | ||
| Differential Roles of M1 and M2 Microglia in Neurodegenerative Diseases | Q38322767 | ||
| Roles of microglia in brain development, tissue maintenance and repair. | Q38396105 | ||
| Potential role of fibronectin in microglia/macrophage activation following cryoinjury in the rat brain: an immunohistochemical study | Q38453584 | ||
| Mitigation of cerebellar neuropathy in globoid cell leukodystrophy mice by AAV-mediated gene therapy | Q38859684 | ||
| Fluoxetine and S-citalopram inhibit M1 activation and promote M2 activation of microglia in vitro | Q38906486 | ||
| Inflammation induces multinucleation of Microglia via PKC inhibition of cytokinesis, generating highly phagocytic multinucleated giant cells | Q39080863 | ||
| Inflammation modulates expression of laminin in the central nervous system following ischemic injury | Q39320621 | ||
| Macrophages, microglial cells, and HLA-DR antigens in fetal and infant brain | Q39462928 | ||
| M2 macrophages phagocytose rituximab-opsonized leukemic targets more efficiently than m1 cells in vitro. | Q39870660 | ||
| Psychosine-induced apoptosis in a mouse oligodendrocyte progenitor cell line is mediated by caspase activation | Q40574853 | ||
| Molecular mechanism of psychosine-induced cell death in human oligodendrocyte cell line | Q40638726 | ||
| Beta-amyloid activated microglia induce cell cycling and cell death in cultured cortical neurons | Q40836274 | ||
| Twenty five years of the "psychosine hypothesis": a personal perspective of its history and present status | Q40868687 | ||
| Inhibition of cytokinesis by a lipid metabolite, psychosine | Q40879707 | ||
| Microglia derive from progenitors, originating from the yolk sac, and which proliferate in the brain | Q40917096 | ||
| The twitcher mouse: a model for Krabbe disease and for experimental therapies | Q40922180 | ||
| Murine model of genetic demyelinating disease: the twitcher mouse | Q40926616 | ||
| Detection of the neurotoxin psychosine in samples of peripheral blood: application in diagnostics and follow-up of Krabbe disease | Q41048073 | ||
| Pathogenesis of HIV-1 associated neurodegeneration | Q41149440 | ||
| P433 | issue | 11 | |
| P921 | main subject | microglia | Q1622829 |
| P304 | page(s) | 1049-1061 | |
| P577 | publication date | 2016-11-01 | |
| P1433 | published in | Journal of Neuroscience Research | Q6295654 |
| P1476 | title | A microglial hypothesis of globoid cell leukodystrophy pathology | |
| P478 | volume | 94 |
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