Different pathophysiology of impaired glucose tolerance in first-degree relatives of individuals with type 2 diabetes mellitus (scientific article published on May 2009)

Insulin resistance and insulin secretory dysfunction are independent predictors of worsening of glucose tolerance during each stage of type 2 diabetes development

Q31979634

Glucose clamp technique: a method for quantifying insulin secretion and resistance

Q34191986

The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes

Q35085591

Follow-up report on the diagnosis of diabetes mellitus

Q35567871

Contributions of beta-cell dysfunction and insulin resistance to the pathogenesis of impaired glucose tolerance and impaired fasting glucose

Q36462545

Elevated plasma glucose 2 h postchallenge predicts defects in beta-cell function

Q40943314

Impaired glucose tolerance--prevalence and conversion to NIDDM.

Q41021267

A sustained increase in plasma free fatty acids impairs insulin secretion in nondiabetic subjects genetically predisposed to develop type 2 diabetes

Q42450726

Different mechanisms for impaired fasting glucose and impaired postprandial glucose tolerance in humans

Q42498882

Diagnostic and therapeutic implications of relationships between fasting, 2-hour postchallenge plasma glucose and hemoglobin a1c values

Q45012486

Insulin sensitivity, insulin secretion, and glucose effectiveness in obese subjects: a minimal model analysis

Q45238787

The natural course of beta-cell function in nondiabetic and diabetic individuals: the Insulin Resistance Atherosclerosis Study

Q46605990

Insulin secretion and insulin sensitivity in people with impaired glucose tolerance.

Q50995966

Effects on insulin secretion and insulin action of a 48-h reduction of plasma free fatty acids with acipimox in nondiabetic subjects genetically predisposed to type 2 diabetes.

Q51478323

Relative conributions of beta-cell function and tissue insulin sensitivity to fasting and postglucose-load glycemia.

Q51552631

Lowering fatty acids potentiates acute insulin response in first degree relatives of people with type II diabetes.

Q51567209

Islet dysfunction in obese women with impaired glucose tolerance.

Q51582214

Quantification of the relationship between insulin sensitivity and beta-cell function in human subjects. Evidence for a hyperbolic function.

Q51598262

The genetic basis of type 2 diabetes mellitus: impaired insulin secretion versus impaired insulin sensitivity.

Q54126868

Pancreatic beta-cell dysfunction as the primary genetic lesion in NIDDM. Evidence from studies in normal glucose-tolerant individuals with a first-degree NIDDM relative.

Q54170134

Beta-cell dysfunction, rather than insulin insensitivity, is the primary defect in familial type 2 diabetes.

Q54423973

Use of a heated superficial hand vein as an alternative site for the measurement of amino acid concentrations and for the study of glucose and alanine kinetics in man

Q70170063

P433

issue

P921

main subject

glucose

pathophysiology

type 2 diabetes

page(s)

602-607

P577

publication date

2009-05-01

P1433

published in

Metabolism

Q15764354

P1476

title

Different pathophysiology of impaired glucose tolerance in first-degree relatives of individuals with type 2 diabetes mellitus

P478

volume

Reverse relations

cites work (P2860)

Q35015726	Dynamics of insulin secretion and the clinical implications for obesity and diabetes
Q33588874	Family history of diabetes, lifestyle factors, and the 7-year incident risk of type 2 diabetes mellitus in middle-aged Japanese men and women
Q64260502	Glucose-dependent phosphorylation signaling pathways and crosstalk to mitochondrial respiration in insulin secreting cells
Q37916697	Measurement of insulin action: a tribute to Sir Harold Himsworth