Effects on insulin secretion and insulin action of a 48-h reduction of plasma free fatty acids with acipimox in nondiabetic subjects genetically predisposed to type 2 diabetes.

scientific article published on 13 February 2007

Effects on insulin secretion and insulin action of a 48-h reduction of plasma free fatty acids with acipimox in nondiabetic subjects genetically predisposed to type 2 diabetes. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1152/AJPENDO.00624.2006
P698PubMed publication ID17299078
P5875ResearchGate publication ID6506482

P50authorAmalia GastaldelliQ43294287
P2093author name stringEugenio Cersosimo
Kenneth Cusi
Mandeep Bajaj
Sangeeta Kashyap
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A sustained increase in plasma free fatty acids impairs insulin secretion in nondiabetic subjects genetically predisposed to develop type 2 diabetesQ42450726
Elevation of free fatty acids induces inflammation and impairs vascular reactivity in healthy subjectsQ42453208
Circulating fatty acids are essential for efficient glucose-stimulated insulin secretion after prolonged fasting in humansQ42461702
Sustained reduction in plasma free fatty acid concentration improves insulin action without altering plasma adipocytokine levels in subjects with strong family history of type 2 diabetesQ42467298
Glucose-induced insulin hypersecretion in lipid-infused healthy subjects is associated with a decrease in plasma norepinephrine concentration and urinary excretionQ43766475
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Insulin resistance and insulin secretory dysfunction as precursors of non-insulin-dependent diabetes mellitus. Prospective studies of Pima IndiansQ43850960
Beta-cell function is a major contributor to oral glucose tolerance in high-risk relatives of four ethnic groups in the U.S.Q44043219
Acute lowering of circulating fatty acids improves insulin secretion in a subset of type 2 diabetes subjectsQ44251616
Nicotinic acid-induced insulin resistance is related to increased circulating fatty acids and fat oxidation but not muscle lipid contentQ44473913
Estimation of insulin secretion rates from C-peptide levels. Comparison of individual and standard kinetic parameters for C-peptide clearanceQ44831737
The effect of pioglitazone on peroxisome proliferator-activated receptor-gamma target genes related to lipid storage in vivoQ44953988
beta-Cell function in subjects spanning the range from normal glucose tolerance to overt diabetes: a new analysisQ45105931
Influence of extended-release nicotinic acid on nonesterified fatty acid flux in the metabolic syndrome with atherogenic dyslipidemiaQ46498930
Lowering fatty acids potentiates acute insulin response in first degree relatives of people with type II diabetes.Q51567209
Impact of nicotinic acid treatment on insulin secretion and insulin sensitivity in low and high insulin responders.Q51579221
Opposite effects of short- and long-term fatty acid infusion on insulin secretion in healthy subjects.Q51584824
The metabolic profile of NIDDM is fully established in glucose-tolerant offspring of two Mexican-American NIDDM parentsQ51603248
Palmitic acid-induced activation of human T-lymphocytes and aortic endothelial cells with production of insulin receptors, reactive oxygen species, cytokines, and lipid peroxidation.Q53617326
Obesity and insulin resistance in humans: a dose-response study.Q54325234
Early metabolic defects in persons at increased risk for non-insulin-dependent diabetes mellitus.Q54346849
P433issue6
P921main subjecttype 2 diabetesQ3025883
preproinsulinQ7240673
P304page(s)E1775-81
P577publication date2007-02-13
P1433published inAmerican Journal of Physiology - Endocrinology and MetabolismQ15765671
P1476titleEffects on insulin secretion and insulin action of a 48-h reduction of plasma free fatty acids with acipimox in nondiabetic subjects genetically predisposed to type 2 diabetes.
P478volume292

Reverse relations

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