Statins in the first-line therapy of acute coronary syndrome - similar to aspirin?

scientific article published on January 2005

Statins in the first-line therapy of acute coronary syndrome - similar to aspirin? is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID2716222
P698PubMed publication ID19641661

P2093author name stringPetr Ostadal
David Alan
Jiri Vejvoda
P2860cites workLocalization of tissue factor in the normal vessel wall and in the atherosclerotic plaqueQ24339425
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Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: implications for plaque stabilizationQ31956534
An HMG-CoA reductase inhibitor, cerivastatin, suppresses growth of macrophages expressing matrix metalloproteinases and tissue factor in vivo and in vitroQ32033463
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Fluvastatin inhibits basal and stimulated plasminogen activator inhibitor 1, but induces tissue type plasminogen activator in cultured human endothelial cellsQ74119638
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Oxidized amino acids: culprits in human atherosclerosis and indicators of oxidative stressQ34658022
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Early vascular benefits of statin therapyQ35574104
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Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokinesQ35749970
Direct in vivo evidence of a vascular statin: a single dose of cerivastatin rapidly increases vascular endothelial responsiveness in healthy normocholesterolaemic subjectsQ35804090
Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. Implications for atherosclerotic plaque stabilityQ37361893
Hemostasis and atherosclerosis.Q40525600
Early statin therapy restores endothelial function in children with familial hypercholesterolemiaQ40613252
Effect of fluvastatin on ischaemia following acute myocardial infarction: a randomized trialQ40616674
Lipid-independent effects of an estrogen-statin combination: inhibition of expression of adhesion molecules and plasminogen activator inhibitor--I in human endothelial cell culturesQ40776539
3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors increase fibrinolytic activity in rat aortic endothelial cells. Role of geranylgeranylation and Rho proteinsQ41005307
Effects of fibrous cap thickness on peak circumferential stress in model atherosclerotic vesselsQ41110144
Inhibitory effect of fluvastatin, an HMG-CoA reductase inhibitor, on the expression of adhesion molecules on human monocyte cell lineQ41152300
Statins do more than just lower cholesterolQ41169571
The effect of early treatment by cerivastatin on the serum level of C-reactive protein, interleukin-6, and interleukin-8 in the patients with unstable angina and non-Q-wave myocardial infarctionQ42164942
Fluvastatin inhibits matrix metalloproteinase-1 expression in human vascular endothelial cellsQ42493329
Elevated plasma levels of free-form of TFPI antigen in hypercholesterolemic patientsQ43515062
Effect of lipid-lowering therapy on early mortality after acute coronary syndromes: an observational studyQ43571946
HMG-CoA reductase inhibition protects the diabetic myocardium from ischemia-reperfusion injuryQ43626599
Non-lipid effects of statin on hypercholesterolemic patients established to have coronary artery disease who remained hypercholesterolemic while eating a step-II dietQ43654962
Cerivastatin, a hydroxymethylglutaryl coenzyme a reductase inhibitor, improves endothelial function in elderly diabetic patients within 3 daysQ43684740
Simvastatin reduces reperfusion injury by modulating nitric oxide synthase expression: an ex vivo study in isolated working rat hearts.Q43686071
Improvement of left ventricular remodeling and function by hydroxymethylglutaryl coenzyme a reductase inhibition with cerivastatin in rats with heart failure after myocardial infarctionQ43721244
Increased nitric oxide bioavailability in endothelial cells contributes to the pleiotropic effect of cerivastatinQ43895513
Withdrawal of statins increases event rates in patients with acute coronary syndromesQ43933090
Statin attenuates increase in C-reactive protein during estrogen replacement therapy in postmenopausal womenQ43943280
Reduced expression of endothelial cell markers after 1 year treatment with simvastatin and atorvastatin in patients with coronary heart diseaseQ43955489
Fluvastatin reduces tissue factor expression and macrophage accumulation in carotid lesions of cholesterol-fed rabbits in the absence of lipid loweringQ43957656
Statin prevents tissue factor expression in human endothelial cells: role of Rho/Rho-kinase and Akt pathwaysQ43961145
Short-term effects of atorvastatin on C-reactive proteinQ43992481
Rosuvastatin, a new HMG-CoA reductase inhibitor, upregulates endothelial nitric oxide synthase and protects from ischemic stroke in miceQ44007043
Overexpression of interleukin-10 by activated T lymphocytes inhibits atherosclerosis in LDL receptor-deficient Mice by altering lymphocyte and macrophage phenotypesQ44011973
Rho/Rho-kinase is involved in the synthesis of tissue factor in human monocytesQ44016826
Effect of diet and treatment with statins on platelet-dependent thrombin generation in hypercholesterolemic subjectsQ44021803
Inhibition of Rho/Rho-kinase signaling downregulates plasminogen activator inhibitor-1 synthesis in cultured human monocytesQ44026877
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Simvastatin reduces expression of cytokines interleukin-6, interleukin-8, and monocyte chemoattractant protein-1 in circulating monocytes from hypercholesterolemic patients.Q44063984
Atorvastatin therapy in hypercholesterolemic patients suppresses cellular uptake of oxidized-LDL by differentiating monocytesQ44064914
The effect of statins on mRNA levels of genes related to inflammation, coagulation, and vascular constriction in HUVEC. Human umbilical vein endothelial cellsQ44134020
Effects of atorvastatin treatment on sICAM-1 and plasma nitric oxide levels in hypercholesterolemic subjectsQ44165719
Simvastatin increases fibrinolytic activity in human peritoneal mesothelial cells independent of cholesterol loweringQ44173347
Strong decrease of high sensitivity C-reactive protein with high-dose atorvastatin in patients with type 2 diabetes mellitusQ44249465
Cerivastatin potentiates nitric oxide release and enos expression through inhibition of isoprenoids synthesis.Q44269540
hsCRP and HDL effects of statins trial (CHEST): rapid effect of statin therapy on C-reactive protein and high-density lipoprotein levels A clinical investigationQ44292384
Atorvastatin, administered at the onset of reperfusion, and independent of lipid lowering, protects the myocardium by up-regulating a pro-survival pathwayQ44307951
Effect of atorvastatin and pravastatin on serum C-reactive proteinQ44321723
High-dose atorvastatin enhances the decline in inflammatory markers in patients with acute coronary syndromes in the MIRACL studyQ44585429
Effect of pravastatin compared with placebo initiated within 24 hours of onset of acute myocardial infarction or unstable angina: the Pravastatin in Acute Coronary Treatment (PACT) trialQ44950890
Statin administration before percutaneous coronary intervention: impact on periprocedural myocardial infarctionQ45098728
Simvastatin acutely reduces myocardial reperfusion injury in vivo by activating the phosphatidylinositide 3-kinase/Akt pathwayQ45099728
Fluvastatin, a 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor, attenuates left ventricular remodeling and failure after experimental myocardial infarctionQ45712799
Pravastatin restored the infarct size-limiting effect of ischemic preconditioning blunted by hypercholesterolemia in the rabbit model of myocardial infarctionQ47252034
Simvastatin reduces monocyte-tissue-factor expression type IIa hypercholesterolaemiaQ47887085
Cholesterol-induced thrombogenicity of the vessel wall: inhibitory effect of fluvastatin.Q50225902
Atorvastatin and thrombogenicity of the carotid atherosclerotic plaque: the ATROCAP study.Q50277148
Effect of omega-3 fatty acids and simvastatin on hemostatic risk factors and postprandial hyperlipemia in patients with combined hyperlipemia.Q51558882
Inhibition of thrombin generation by simvastatin and lack of additive effects of aspirin in patients with marked hypercholesterolemia.Q52218975
Suppression of endothelial nitric oxide production after withdrawal of statin treatment is mediated by negative feedback regulation of rho GTPase gene transcription.Q52541795
Fibrinogen and risk of cardiovascular disease. The Framingham Study.Q52588834
Fluvastatin and tissue factor pathway inhibitor in type IIA and IIB hyperlipidemia and in acute myocardial infarction.Q53965155
Statin therapy and the acute inflammatory response after coronary artery bypass graftingQ57243098
Vastatins Inhibit Tissue Factor in Cultured Human MacrophagesQ57398943
Effect of atorvastatin and fluvastatin on the expression of plasminogen activator inhibitor type-1 in cultured human endothelial cellsQ58106726
Simvastatin inhibits the monocyte expression of proinflammatory cytokines in patients with hypercholesterolemiaQ58421218
Inhibition of tissue-factor-mediated thrombin generation by simvastatinQ58421229
Relationship between prothrombin activation fragment F1 + 2 and serum cholesterolQ59536862
Haemostatic function and ischaemic heart disease: principal results of the Northwick Park Heart StudyQ69886150
Fibrinogen as a risk factor for stroke and myocardial infarctionQ71438059
Effect of Cholesterol Lowering on Intravascular Pools of TFPI and Its Anticoagulant Potential in Type II HyperlipoproteinemiaQ71843129
Human monocyte-derived macrophages induce collagen breakdown in fibrous caps of atherosclerotic plaques. Potential role of matrix-degrading metalloproteinases and implications for plaque ruptureQ72034135
P433issue1
P921main subjectaspirinQ18216
acute coronary syndromeQ266018
P304page(s)9-16
P577publication date2005-01-01
P1433published inExperimental & Clinical CardiologyQ5421099
P1476titleStatins in the first-line therapy of acute coronary syndrome - similar to aspirin?
P478volume10

Reverse relations

cites work (P2860)
Q80675789Immediate effect of fluvastatin on lipid levels in acute coronary syndrome
Q36768488Statins as first-line therapy for acute coronary syndrome?

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