Initiation of cytokinesis is controlled through multiple modes of regulation of the Sid2p-Mob1p kinase complex

scientific article published on April 2004

Initiation of cytokinesis is controlled through multiple modes of regulation of the Sid2p-Mob1p kinase complex is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/MCB.24.8.3262-3276.2004
P932PMC publication ID381652
P698PubMed publication ID15060149

P2093author name stringDavid A Guertin
Dannel McCollum
Ming-Chin Hou
P2860cites workA human homolog of Drosophila warts tumor suppressor, h-warts, localized to mitotic apparatus and specifically phosphorylated during mitosisQ22010636
Molecular cloning and characterization of a conserved nuclear serine(threonine) protein kinaseQ24319928
The Cbk1p pathway is important for polarized cell growth and cell separation in Saccharomyces cerevisiaeQ27931512
The Saccharomyces cerevisiae Mob2p-Cbk1p kinase complex promotes polarized growth and acts with the mitotic exit network to facilitate daughter cell-specific localization of Ace2p transcription factorQ27932966
The Dbf2 and Dbf20 protein kinases of budding yeast are activated after the metaphase to anaphase cell cycle transitionQ27934647
RAM: a conserved signaling network that regulates Ace2p transcriptional activity and polarized morphogenesisQ27935704
Cbk1p, a protein similar to the human myotonic dystrophy kinase, is essential for normal morphogenesis in Saccharomyces cerevisiaeQ27935892
Protein kinase Cdc15 activates the Dbf2-Mob1 kinase complexQ27937216
Yeast Cbk1 and Mob2 activate daughter-specific genetic programs to induce asymmetric cell fates.Q27939027
Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeastQ28131604
A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coliQ28131613
Thiamine-repressible expression vectors pREP and pRIP for fission yeastQ70536009
Cytokinesis in fission yeast Schizosaccharomyces pombeQ73572491
The S. pombe orthologue of the S. cerevisiae mob1 gene is essential and functions in signalling the onset of septum formationQ73685369
Mob1p interacts with the Sid2p kinase and is required for cytokinesis in fission yeastQ73849586
S. pombe cdc11p, together with sid4p, provides an anchor for septation initiation network proteins on the spindle pole bodyQ77060419
Studies on the transformation of intact yeast cells by the LiAc/SS-DNA/PEG procedureQ28131658
Mitotic kinases as regulators of cell division and its checkpointsQ28202545
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociationQ28206029
Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinaseQ28301071
Pak1 kinase homodimers are autoinhibited in trans and dissociated upon activation by Cdc42 and Rac1Q28609687
Ligand-induced, receptor-mediated dimerization and activation of EGF receptorQ28646134
Molecular genetic analysis of fission yeast Schizosaccharomyces pombeQ29547703
The tricornered gene, which is required for the integrity of epidermal cell extensions, encodes the Drosophila nuclear DBF2-related kinase.Q30306513
The role of lats in cell cycle regulation and tumorigenesisQ33755124
Regulation of the mitotic exit protein kinases Cdc15 and Dbf2.Q33948201
DBF2 protein kinase binds to and acts through the cell cycle-regulated MOB1 proteinQ33995013
Men and sin: what's the difference?Q34102523
Chromosome segregation and cancer: cutting through the mysteryQ34119639
Timing is everything: regulation of mitotic exit and cytokinesis by the MEN and SIN.Q34134487
Animal cell cytokinesisQ34425177
The role of the sid1p kinase and cdc14p in regulating the onset of cytokinesis in fission yeastQ34485704
Cytokinesis in eukaryotesQ34662537
Neuronal cell shape and neurite initiation are regulated by the Ndr kinase SAX-1, a member of the Orb6/COT-1/warts serine/threonine kinase familyQ34759983
NDR family of AGC kinases--essential regulators of the cell cycle and morphogenesisQ35163941
cdc2 phosphorylation is required for its interaction with cyclin.Q35933286
Sid2p, a spindle pole body kinase that regulates the onset of cytokinesisQ36301490
Fission yeast orb6, a ser/thr protein kinase related to mammalian rho kinase and myotonic dystrophy kinase, is required for maintenance of cell polarity and coordinates cell morphogenesis with the cell cycleQ36494992
MOB1, an essential yeast gene required for completion of mitosis and maintenance of ploidyQ36848040
Sid4p is required to localize components of the septation initiation pathway to the spindle pole body in fission yeast.Q36967829
The cdc7 protein kinase is a dosage dependent regulator of septum formation in fission yeastQ37634039
The spindle pole body protein Cdc11p links Sid4p to the fission yeast septation initiation networkQ39540605
High efficiency transformation ofSchizosaccharomyces pombeby electroporationQ40411959
LATS1 tumor suppressor regulates G2/M transition and apoptosisQ40750103
Fission yeast Clp1p phosphatase regulates G2/M transition and coordination of cytokinesis with cell cycle progression.Q40793180
Ndr protein kinase is regulated by phosphorylation on two conserved sequence motifsQ40917418
Phosphorylation at Thr167 is required for Schizosaccharomyces pombe p34cdc2 functionQ41082941
Efficient targeted integration at leu1-32 and ura4-294 in Schizosaccharomyces pombe.Q41965845
Vectors for the expression of tagged proteins in Schizosaccharomyces pombe.Q42543117
Flp1, a fission yeast orthologue of the s. cerevisiae CDC14 gene, is not required for cyclin degradation or rum1p stabilisation at the end of mitosisQ43781967
The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferationQ46192247
The Spg1p GTPase is an essential, dosage-dependent inducer of septum formation in Schizosaccharomyces pombeQ48048585
Human homologue of Drosophila lats, LATS1, negatively regulate growth by inducing G(2)/M arrest or apoptosis.Q52591879
Mob2p interacts with the protein kinase Orb6p to promote coordination of cell polarity with cell cycle progression.Q54179045
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectSid2-Mob1 complexQ22328833
Septation initiation network (SIN) componentQ62647870
Septation initiation network (SIN) componentQ62660030
P304page(s)3262-3276
P577publication date2004-04-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleInitiation of cytokinesis is controlled through multiple modes of regulation of the Sid2p-Mob1p kinase complex
P478volume24

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cites work (P2860)
Q30540924A 2D/3D image analysis system to track fluorescently labeled structures in rod-shaped cells: application to measure spindle pole asymmetry during mitosis
Q41883136An Extended, Boolean Model of the Septation Initiation Network in S.Pombe Provides Insights into Its Regulation.
Q30377503Characterization and evolution of the cell cycle-associated mob domain-containing proteins in eukaryotes
Q33811922Characterization of the roles of Blt1p in fission yeast cytokinesis
Q35863039Characterization of ypa1 and ypa2, the Schizosaccharomyces pombe orthologs of the peptidyl proyl isomerases that activate PP2A, reveals a role for Ypa2p in the regulation of cytokinesis
Q34119685Differential NDR/LATS interactions with the human MOB family reveal a negative role for human MOB2 in the regulation of human NDR kinases.
Q38034963Ensuring the faithful execution of cytokinesis in Schizosaccharomyces pombe.
Q30476013Etd1p is a novel protein that links the SIN cascade with cytokinesis
Q37557455Feedback regulation of SIN by Etd1 and Rho1 in fission yeast.
Q42196496Hydrophobic motif phosphorylation coordinates activity and polar localization of the Neurospora crassa nuclear Dbf2-related kinase COT1.
Q34895571Isolation of mutations that bypass the requirement of the septation initiation network for septum formation and conidiation in Aspergillus nidulans.
Q51987013Lats2 is an essential mitotic regulator required for the coordination of cell division.
Q37871662MOB control: reviewing a conserved family of kinase regulators
Q24308682MOBKL1A/MOBKL1B phosphorylation by MST1 and MST2 inhibits cell proliferation
Q37308262Measuring affinities of fission yeast spindle pole body proteins in live cells across the cell cycle
Q93231149Mechanisms of contractile ring tension production and constriction
Q24670738Mob as tumor suppressor is activated by Hippo kinase for growth inhibition in Drosophila
Q30493988Mob4 plays a role in spindle focusing in Drosophila S2 cells
Q33623789Mutual dependence of Mob1 and the chromosomal passenger complex for localization during mitosis
Q34512601NDR kinases regulate essential cell processes from yeast to humans
Q24627940Nuclear DBF-2-related kinases are essential regulators of cytokinesis in bloodstream stage Trypanosoma brucei
Q27302824Phospho-regulation of the Neurospora crassa septation initiation network
Q27930539Phosphorylation-dependent regulation of the F-BAR protein Hof1 during cytokinesis
Q38025595Polar opposites: Fine-tuning cytokinesis through SIN asymmetry
Q36371333Protein kinases of the Hippo pathway: regulation and substrates
Q24297305Regulation of NDR protein kinase by hydrophobic motif phosphorylation mediated by the mammalian Ste20-like kinase MST3
Q35027563Regulation of Rho-GEF Rgf3 by the arrestin Art1 in fission yeast cytokinesis
Q21559568Relationships between cell cycle regulator gene copy numbers and protein expression levels in Schizosaccharomyces pombe
Q37792480Tales of RAM and MOR: NDR kinase signaling in fungal morphogenesis
Q33356931The Arabidopsis thaliana Mob1A gene is required for organ growth and correct tissue patterning of the root tip.
Q36854884The meiosis-specific Sid2p-related protein Slk1p regulates forespore membrane assembly in fission yeast
Q27342230The septation initiation network controls the assembly of nodes containing Cdr2p for cytokinesis in fission yeast
Q40445660Trypanosoma brucei MOB1 is required for accurate and efficient cytokinesis but not for exit from mitosis

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