Regulation of NDR protein kinase by hydrophobic motif phosphorylation mediated by the mammalian Ste20-like kinase MST3

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Regulation of NDR protein kinase by hydrophobic motif phosphorylation mediated by the mammalian Ste20-like kinase MST3 is …
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scholarly articleQ13442814

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P356DOI10.1128/MCB.25.24.11019-11029.2005
P3181OpenCitations bibliographic resource ID548945
P932PMC publication ID1316964
P698PubMed publication ID16314523
P5875ResearchGate publication ID7453548

P50authorBrian HemmingsQ4964012
Alexander HergovichQ39183117
P2093author name stringMario R Stegert
Rastislav Tamaskovic
Samuel J Bichsel
P2860cites workCalcium regulation of Ndr protein kinase mediated by S100 calcium-binding proteinsQ22003960
MST, a physiological caspase substrate, highly sensitizes apoptosis both upstream and downstream of caspase activationQ24291002
MST4, a new Ste20-related kinase that mediates cell growth and transformation via modulating ERK pathwayQ24291824
Cloning of MASK, a novel member of the mammalian germinal center kinase III subfamily, with apoptosis-inducing propertiesQ24291998
Phosphorylation and dimerization regulate nucleocytoplasmic shuttling of mammalian STE20-like kinase (MST)Q24292204
Mechanism of activation of NDR (nuclear Dbf2-related) protein kinase by the hMOB1 proteinQ24296945
Caspase activation of mammalian sterile 20-like kinase 3 (Mst3). Nuclear translocation and induction of apoptosisQ24301069
Crystal structure of an activated Akt/protein kinase B ternary complex with GSK3-peptide and AMP-PNPQ24318633
YSK1 is activated by the Golgi matrix protein GM130 and plays a role in cell migration through its substrate 14-3-3zetaQ24318811
Regulation of NDR2 protein kinase by multi-site phosphorylation and the S100B calcium-binding proteinQ24318869
Molecular cloning and characterization of a conserved nuclear serine(threonine) protein kinaseQ24319928
The protein kinase complement of the human genomeQ24324497
Human Mob proteins regulate the NDR1 and NDR2 serine-threonine kinasesQ24324672
Mechanism of Ca2+-mediated regulation of NDR protein kinase through autophosphorylation and phosphorylation by an upstream kinaseQ24337423
Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by RasQ24338128
The crystal structure of a phosphorylase kinase peptide substrate complex: kinase substrate recognitionQ24532833
Human NDR kinases are rapidly activated by MOB proteins through recruitment to the plasma membrane and phosphorylationQ24535404
Determination of the affinity of each component of a composite quaternary transition-state analogue complex of creatine kinase.Q44008702
Control of dendritic branching and tiling by the Tricornered-kinase/Furry signaling pathway in Drosophila sensory neurons.Q44504540
Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathwayQ44591663
Mechanosensory neurite termination and tiling depend on SAX-2 and the SAX-1 kinase.Q46326338
The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila.Q52100108
Activation of the Ste20-like oxidant stress response kinase-1 during the initial stages of chemical anoxia-induced necrotic cell death. Requirement for dual inputs of oxidant stress and increased cytosolic [Ca2+]Q73853977
MST1-JNK promotes apoptosis via caspase-dependent and independent pathwaysQ74152681
Caspase cleavage of MST1 promotes nuclear translocation and chromatin condensationQ24555220
The Saccharomyces cerevisiae Mob2p-Cbk1p kinase complex promotes polarized growth and acts with the mitotic exit network to facilitate daughter cell-specific localization of Ace2p transcription factorQ27932966
RAM: a conserved signaling network that regulates Ace2p transcriptional activity and polarized morphogenesisQ27935704
Protein kinase Cdc15 activates the Dbf2-Mob1 kinase complexQ27937216
Yeast Cbk1 and Mob2 activate daughter-specific genetic programs to induce asymmetric cell fates.Q27939027
The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1Q28116287
The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosisQ29619851
hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and wartsQ29620457
The tricornered gene, which is required for the integrity of epidermal cell extensions, encodes the Drosophila nuclear DBF2-related kinase.Q30306513
Both phosphorylation and caspase-mediated cleavage contribute to regulation of the Ste20-like protein kinase Mst1 during CD95/Fas-induced apoptosis.Q33940485
Caspase-catalyzed cleavage and activation of Mst1 correlates with eosinophil but not neutrophil apoptosisQ34124636
Regulation of mammalian STE20-like kinase 2 (MST2) by protein phosphorylation/dephosphorylation and proteolysisQ34173448
Mammalian Sterile20-like kinase 1 and the regulation of apoptosisQ34322331
Identification and characterization of the nuclear import and export signals of the mammalian Ste20-like protein kinase 3.Q34340089
Control of cell proliferation and apoptosis by mob as tumor suppressor, matsQ34402685
The IAP proteins: caspase inhibitors and beyondQ34467672
Neuronal cell shape and neurite initiation are regulated by the Ndr kinase SAX-1, a member of the Orb6/COT-1/warts serine/threonine kinase familyQ34759983
NDR family of AGC kinases--essential regulators of the cell cycle and morphogenesisQ35163941
The inhibitors of apoptosis: there is more to life than Bcl2.Q35591690
Survivin, versatile modulation of cell division and apoptosis in cancerQ35591693
Caspase activation - stepping on the gas or releasing the brakes? Lessons from humans and fliesQ35743108
New methodologies for measuring protein interactions in vivo and in vitroQ36046401
The Drosophila Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosisQ36336754
Fission yeast orb6, a ser/thr protein kinase related to mammalian rho kinase and myotonic dystrophy kinase, is required for maintenance of cell polarity and coordinates cell morphogenesis with the cell cycleQ36494992
Initiation of cytokinesis is controlled through multiple modes of regulation of the Sid2p-Mob1p kinase complexQ37276881
Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vectorQ40773079
Ndr protein kinase is regulated by phosphorylation on two conserved sequence motifsQ40917418
A constitutively active and nuclear form of the MAP kinase ERK2 is sufficient for neurite outgrowth and cell transformationQ40997506
P433issue24
P407language of work or nameEnglishQ1860
P921main subjectcell biologyQ7141
phosphorylationQ242736
protein serine/threonine kinase activityQ14326094
Serine/threonine kinase 24Q21117407
hydrophobicityQ41854968
P304page(s)11019-11029
P577publication date2005-12-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleRegulation of NDR protein kinase by hydrophobic motif phosphorylation mediated by the mammalian Ste20-like kinase MST3
P478volume25

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cites work (P2860)
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