Rapid detection, discovery, and identification of post-translationally myristoylated proteins during apoptosis using a bio-orthogonal azidomyristate analog

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Rapid detection, discovery, and identification of post-translationally myristoylated proteins during apoptosis using a bio-orthogonal azidomyristate analog is …
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scholarly articleQ13442814

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P356DOI10.1096/FJ.07-9198COM
P932PMC publication ID2865240
P698PubMed publication ID17932026
P5875ResearchGate publication ID5913261

P50authorCarolyn BertozziQ7442
Luc G. BerthiaumeQ40685909
John R. FalckQ42055496
Jennifer A PrescherQ67221954
Gurram RajaiahQ114452088
P2093author name stringDale D O Martin
Gonzalo L Vilas
P2860cites workBcl-XL cooperatively associates with the Bap31 complex in the endoplasmic reticulum, dependent on procaspase-8 and Ced-4 adaptorQ41062127
Treatment of T cells with 2-hydroxymyristic acid inhibits the myristoylation and alters the stability of p56lckQ41528348
Metabolic activation of 2-substituted derivatives of myristic acid to form potent inhibitors of myristoyl CoA:protein N-myristoyltransferaseQ41714481
Apoptotic cleavage of cytoplasmic dynein intermediate chain and p150(Glued) stops dynein-dependent membrane motility.Q41955321
Amino acid residue penultimate to the amino-terminal gly residue strongly affects two cotranslational protein modifications, N-myristoylation and N-acetylationQ43513032
Investigating cellular metabolism of synthetic azidosugars with the Staudinger ligationQ44244385
C-terminal 15 kDa fragment of cytoskeletal actin is posttranslationally N-myristoylated upon caspase-mediated cleavage and targeted to mitochondriaQ44371518
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Amino-terminal processing of proteins by N-myristoylation. Substrate specificity of N-myristoyl transferaseQ70322270
Proteolytic activation of protein kinase C-epsilon by caspase-mediated processing and transduction of antiapoptotic signalsQ74666995
Rapid cytochrome c release, activation of caspases 3, 6, 7 and 8 followed by Bap31 cleavage in HeLa cells treated with photodynamic therapyQ77518937
N-myristoyltransferase 2 expression in human colon cancer: cross-talk between the calpain and caspase systemQ82791181
???Q28319421
MYRbase: analysis of genome-wide glycine myristoylation enlarges the functional spectrum of eukaryotic myristoylated proteinsQ21194850
Regulation of NDR protein kinase by hydrophobic motif phosphorylation mediated by the mammalian Ste20-like kinase MST3Q24297305
Caspase activation of mammalian sterile 20-like kinase 3 (Mst3). Nuclear translocation and induction of apoptosisQ24301069
A second mammalian N-myristoyltransferaseQ24317812
A tagging-via-substrate technology for detection and proteomics of farnesylated proteinsQ24562961
Cell surface engineering by a modified Staudinger reactionQ28138842
The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complexQ28141249
Regulation of enzymatic activity by active site fatty acylation. A new role for long chain fatty acid acylation of proteinsQ28250243
Apoptosis: an overviewQ28254960
The biology and enzymology of protein N-myristoylationQ28507262
Glutamate-cysteine ligase attenuates TNF-induced mitochondrial injury and apoptosisQ28509634
Posttranslational N-myristoylation of BID as a molecular switch for targeting mitochondria and apoptosisQ28647600
Apoptosis and carcinogenesisQ33722362
N-terminal protein acylation confers localization to cholesterol, sphingolipid-enriched membranes but not to lipid rafts/caveolaeQ33948557
Two N-myristoyltransferase isozymes play unique roles in protein myristoylation, proliferation, and apoptosisQ34013237
Palmitoylation of ligands, receptors, and intracellular signaling moleculesQ34578256
Posttranslational myristoylation of caspase-activated p21-activated protein kinase 2 (PAK2) potentiates late apoptotic eventsQ34597799
Many cuts to ruin: a comprehensive update of caspase substratesQ35091412
Prediction of lipid posttranslational modifications and localization signals from protein sequences: big-Pi, NMT and PTS1Q35207744
Membrane targeting of lipid modified signal transduction proteins.Q35891428
Novel use of an iodo-myristyl-CoA analog identifies a semialdehyde dehydrogenase in bovine liverQ36785533
Chemical inhibition of myristoylation of the G-protein Gi1 alpha by 2-hydroxymyristate does not interfere with its palmitoylation or membrane association. Evidence that palmitoylation, but not myristoylation, regulates membrane attachmentQ38362303
Palmitoylation of apolipoprotein B is required for proper intracellular sorting and transport of cholesteroyl esters and triglyceridesQ38479311
Functional roles for fatty acylated amino-terminal domains in subcellular localizationQ38614617
Chemical probes for the rapid detection of Fatty-acylated proteins in Mammalian cellsQ40170295
Tagging-via-substrate strategy for probing O-GlcNAc modified proteins.Q40410441
Constructing azide-labeled cell surfaces using polysaccharide biosynthetic pathwaysQ40635507
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectapoptotic processQ14599311
P304page(s)797-806
P577publication date2007-10-10
P1433published inFASEB JournalQ520194
P1476titleRapid detection, discovery, and identification of post-translationally myristoylated proteins during apoptosis using a bio-orthogonal azidomyristate analog
P478volume22

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