Imaging beyond the proteome

scientific article published on 17 July 2012

Imaging beyond the proteome is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1039/C2CC31845H
P932PMC publication ID3660043
P698PubMed publication ID22801420
P5875ResearchGate publication ID229155600

P50authorCarolyn BertozziQ7442
P2093author name stringPamela V Chang
P2860cites workBioorthogonal Click Chemistry: Covalent Labeling in Living SystemsQ114559611
Circular permutation and receptor insertion within green fluorescent proteinsQ21045408
A tagging-via-substrate technology for detection and proteomics of farnesylated proteinsQ24562961
Fast, cell-compatible click chemistry with copper-chelating azides for biomolecular labelingQ24602278
Labeling live cells by copper-catalyzed alkyne--azide click chemistryQ24606444
The chemical biology of protein phosphorylationQ24620636
Rapid Cu-free click chemistry with readily synthesized biarylazacyclooctynonesQ24623486
Synthesis of a fluorogenic cyclooctyne activated by Cu-free click chemistryQ24625140
Bioorthogonal chemistry: fishing for selectivity in a sea of functionalityQ24629024
Brain tissue lipidomics: direct probing using matrix-assisted laser desorption/ionization mass spectrometryQ24632101
A bioorthogonal quadricyclane ligationQ24632599
Tetrazine ligation: fast bioconjugation based on inverse-electron-demand Diels-Alder reactivityQ24643169
A hydrophilic azacyclooctyne for Cu-free click chemistryQ24648014
A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafishQ24649479
Imaging cell surface glycans with bioorthogonal chemical reportersQ24651255
Selective labeling of living cells by a photo-triggered click reactionQ24657238
A genetically encoded fluorescent reporter reveals oscillatory phosphorylation by protein kinase CQ24675024
Copper-free click chemistry for dynamic in vivo imagingQ24675560
Label-free imaging of lipid dynamics using Coherent Anti-stokes Raman Scattering (CARS) and Stimulated Raman Scattering (SRS) microscopyQ27025182
Reducing the environmental sensitivity of yellow fluorescent protein. Mechanism and applicationsQ27632278
Cell surface engineering by a modified Staudinger reactionQ28138842
Click Chemistry: Diverse Chemical Function from a Few Good ReactionsQ28204398
A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applicationsQ28213193
A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynesQ28219495
Engineering chemical reactivity on cell surfaces through oligosaccharide biosynthesisQ28239786
Copper-free click chemistry in living animalsQ33719594
Organelle-targetable fluorescent probes for imaging hydrogen peroxide in living cells via SNAP-Tag protein labelingQ33773394
A genetically encoded reporter of synaptic activity in vivoQ33809219
Rapid detection, discovery, and identification of post-translationally myristoylated proteins during apoptosis using a bio-orthogonal azidomyristate analogQ33832295
Detection of glutamate release from neurons by genetically encoded surface-displayed FRET nanosensorsQ33842919
Metabolic labeling of sialic acids in living animals with alkynyl sugarsQ33845967
Imaging of the intracellular topography of copper with a fluorescent sensor and by synchrotron x-ray fluorescence microscopyQ33913850
Real-time bioluminescence imaging of glycans on live cells.Q33932166
Peptidotriazoles on solid phase: [1,2,3]-triazoles by regiospecific copper(i)-catalyzed 1,3-dipolar cycloadditions of terminal alkynes to azidesQ33958790
Calcium Green FlAsH as a genetically targeted small-molecule calcium indicatorQ34017561
MALDI imaging of lipid biochemistry in tissues by mass spectrometryQ34028743
Spatio-temporal dynamics of protein kinase B/Akt signaling revealed by a genetically encoded fluorescent reporterQ34036123
Studying single living cells and chromosomes by confocal Raman microspectroscopyQ34068399
Neurogenesis in adult primate neocortex: an evaluation of the evidenceQ34112402
Aquaporin-3 mediates hydrogen peroxide uptake to regulate downstream intracellular signalingQ34115487
Multicolor and electron microscopic imaging of connexin traffickingQ34124663
Readily accessible bicyclononynes for bioorthogonal labeling and three-dimensional imaging of living cells.Q34139183
Controlling the double helixQ34172152
Increasing the efficacy of bioorthogonal click reactions for bioconjugation: a comparative studyQ34200738
Bioconjugation with strained alkenes and alkynesQ34201353
Chemoselective approaches to glycoprotein assemblyQ34371750
A metabolic labeling approach toward proteomic analysis of mucin-type O-linked glycosylationQ34386471
The sweet and sour of cancer: glycans as novel therapeutic targetsQ34439560
Probing mucin-type O-linked glycosylation in living animalsQ34460997
A selective turn-on fluorescent sensor for imaging copper in living cells.Q34482296
Biocompatible copper(I) catalysts for in vivo imaging of glycansQ34495916
Nox2 redox signaling maintains essential cell populations in the brainQ34504631
Bioorthogonal chemical reporters for analyzing protein lipidation and lipid traffickingQ34508699
Boronate-based fluorescent probes for imaging cellular hydrogen peroxideQ34565753
Trafficking and signaling by fatty-acylated and prenylated proteinsQ34575170
Evaluation of Alkyne‐Modified Isoprenoids as Chemical Reporters of Protein PrenylationQ34679579
Synthetic fluorescent sensors for studying the cell biology of metalsQ34750478
Transition states of strain-promoted metal-free click chemistry: 1,3-dipolar cycloadditions of phenyl azide and cyclooctynesQ34764416
Calcium-dependent copper redistributions in neuronal cells revealed by a fluorescent copper sensor and X-ray fluorescence microscopy.Q34794984
Selective fluorescence labeling of lipids in living cellsQ34922262
Reactivity and regioselectivity in 1,3-dipolar cycloadditions of azides to strained alkynes and alkenes: a computational studyQ34982330
Creating new fluorescent probes for cell biology.Q35014035
A targetable fluorescent sensor reveals that copper-deficient SCO1 and SCO2 patient cells prioritize mitochondrial copper homeostasis.Q35019411
Glycoproteomic probes for fluorescent imaging of fucosylated glycans in vivoQ35033695
Metabolic labeling of fucosylated glycans in developing zebrafishQ35051939
Alkynyl-farnesol reporters for detection of protein S-prenylation in cellsQ39627646
A novel imaging approach for early detection of prostate cancer based on endogenous zinc sensingQ39683180
Rapid multilabel detection of geranylgeranylated proteins by using bioorthogonal ligation chemistryQ39731203
Visualizing ascorbate-triggered release of labile copper within living cells using a ratiometric fluorescent sensorQ39755434
Imaging the lipidome: omega-alkynyl fatty acids for detection and cellular visualization of lipid-modified proteinsQ39841404
Label-free biomedical imaging with high sensitivity by stimulated Raman scattering microscopyQ39903580
Preparation and use of Coppersensor-1, a synthetic fluorophore for live-cell copper imagingQ40150097
Molecular imaging of hydrogen peroxide produced for cell signalingQ40151095
Chemical probes for the rapid detection of Fatty-acylated proteins in Mammalian cellsQ40170295
Intracellular imaging of HCV RNA and cellular lipids by using simultaneous two-photon fluorescence and coherent anti-Stokes Raman scattering microscopiesQ40214972
In vivo chemical modification of proteins (post-translational modification).Q40261687
Peroxisome proliferator-activated receptor alpha antagonism inhibits hepatitis C virus replicationQ40326825
Insulin disrupts beta-adrenergic signalling to protein kinase A in adipocytesQ40370148
A selective, cell-permeable optical probe for hydrogen peroxide in living cellsQ40488332
Method to overcome photoreaction, a serious drawback to the use of dichlorofluorescin in evaluation of reactive oxygen speciesQ40650803
The medicinal chemistry of the azido group.Q40670548
Fluorescence ratio imaging of cyclic AMP in single cellsQ41695021
Development and evaluation of new cyclooctynes for cell surface glycan imaging in cancer cells.Q42206290
Thiacycloalkynes for copper-free click chemistryQ42217131
Bioimaging TOF-SIMS: localization of cholesterol in rat kidney sectionsQ42461750
Discriminating basal cell carcinoma from its surrounding tissue by Raman spectroscopyQ42524551
Transport of 13C-oleate in adipocytes measured using multi imaging mass spectrometryQ42824014
A pair of fluorescent resonance energy transfer-based probes for tyrosine phosphorylation of the CrkII adaptor protein in vivo.Q42828083
A targetable fluorescent probe for imaging hydrogen peroxide in the mitochondria of living cellsQ42931877
Aza-dibenzocyclooctynes for fast and efficient enzyme PEGylation via copper-free (3+2) cycloadditionQ43213727
Bioimaging of nitric oxide with fluorescent indicators based on the rhodamine chromophoreQ43608837
Fluorescent sensors for Zn(2+) based on a fluorescein platform: synthesis, properties and intracellular distributionQ43699962
Deep-sea archaea fix and share nitrogen in methane-consuming microbial consortiaQ43861974
Detection and imaging of zinc secretion from pancreatic beta-cells using a new fluorescent zinc indicatorQ43870970
Discrete microdomains with high concentration of cAMP in stimulated rat neonatal cardiac myocytesQ43901717
A novel, cell-permeable, fluorescent probe for ratiometric imaging of zinc ion.Q44122593
ZP4, an improved neuronal Zn2+ sensor of the Zinpyr familyQ44311279
Relationships between degree of binding, cytotoxicity and cytoagglutinating activity of plant-derived agglutinins in normal lymphocytes and cultured leukemic cell linesQ44403862
Fluorescent indicators for Akt/protein kinase B and dynamics of Akt activity visualized in living cellsQ44457883
A novel two-fluorophore approach to ratiometric sensing of Zn(2+).Q44585828
Near-infrared Raman spectroscopy for optical diagnosis of lung cancer.Q44644565
Emission ratiometric imaging of intracellular zinc: design of a benzoxazole fluorescent sensor and its application in two-photon microscopyQ44735043
Spontaneous network activity visualized by ultrasensitive Ca(2+) indicators, yellow Cameleon-NanoQ44756954
Highly sensitive fluorescence probes for nitric oxide based on boron dipyrromethene chromophore-rational design of potentially useful bioimaging fluorescence probeQ44793901
Neurodegenerative diseases and oxidative stressQ44805871
Control of bacteria adhesion by cell-wall engineeringQ44810710
DPA-substituted coumarins as chemosensors for zinc(II): modulation of the chemosensory characteristics by variation of the position of the chelate on the coumarinQ44873107
Bright fluorescent chemosensor platforms for imaging endogenous pools of neuronal zincQ44880751
Genetically encoded fluorescent reporters of histone methylation in living cellsQ44891925
Mass spectrometric imaging of lipids in brain tissueQ44999954
Nucleic acid-triggered fluorescent probe activation by the Staudinger reactionQ45188228
Membrane-permeable and -impermeable sensors of the Zinpyr family and their application to imaging of hippocampal zinc in vivoQ45195485
A simple and effective strategy to increase the sensitivity of fluorescence probes in living cells.Q45942283
Constructing and exploiting the fluorescent protein paintbox (Nobel Lecture).Q45957909
Fluorescent indicators for cytosolic calcium based on rhodamine and fluorescein chromophoresQ46089769
Coumarin-based chemosensors for zinc(II): toward the determination of the design algorithm for CHEF-type and ratiometric probesQ46372896
Intracellular messenger function of hydrogen peroxide and its regulation by peroxiredoxinsQ28240848
Fluorescent indicators for Ca2+ based on green fluorescent proteins and calmodulinQ28247685
Nucleophilic catalysis of oxime ligationQ28269416
Chemical remodelling of cell surfaces in living animalsQ28277825
In vivo imaging of membrane-associated glycans in developing zebrafishQ28278605
Mass spectrometry sampling under ambient conditions with desorption electrospray ionizationQ28288035
Coherent anti-stokes Raman scattering microscopy: chemical imaging for biology and medicineQ28288069
A strain-promoted [3 + 2] azide-alkyne cycloaddition for covalent modification of biomolecules in living systemsQ28293869
Cycling of O-linked beta-N-acetylglucosamine on nucleocytoplasmic proteinsQ28299550
Detection Technologies. Ambient mass spectrometryQ28302544
Identification of palmitoylated mitochondrial proteins using a bio-orthogonal azido-palmitate analogueQ28567516
Innovation: Looking forward to seeing calciumQ29040650
Membrane recognition by phospholipid-binding domainsQ29614848
A high signal-to-noise Ca(2+) probe composed of a single green fluorescent proteinQ29616188
Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicatorsQ29619969
Midzone activation of aurora B in anaphase produces an intracellular phosphorylation gradientQ30438972
High-resolution quantitative imaging of mammalian and bacterial cells using stable isotope mass spectrometryQ30445392
3D imaging by mass spectrometry: a new frontierQ30457575
Mass spectrometric imaging for biomedical tissue analysisQ30475508
Single-cell Raman and fluorescence microscopy reveal the association of lipid bodies with phagosomes in leukocytesQ30476034
Chemical imaging of tissue in vivo with video-rate coherent anti-Stokes Raman scattering microscopyQ30476363
Imaging cellular signals in the heart in vivo: Cardiac expression of the high-signal Ca2+ indicator GCaMP2.Q30477207
Determination of hierarchical relationship of Src and Rac at subcellular locations with FRET biosensors.Q30484062
Real-time imaging of histone H4 hyperacetylation in living cellsQ30490570
Label-free quantitative analysis of lipid metabolism in living Caenorhabditis elegansQ30493020
Visualizing enveloping layer glycans during zebrafish early embryogenesisQ30495076
Metabolic cross-talk allows labeling of O-linked beta-N-acetylglucosamine-modified proteins via the N-acetylgalactosamine salvage pathwayQ30498243
Highly specific label-free molecular imaging with spectrally tailored excitation stimulated Raman scattering (STE-SRS) microscopyQ30525196
Video-rate molecular imaging in vivo with stimulated Raman scatteringQ30525440
An expanded palette of genetically encoded Ca²⁺ indicatorsQ30533809
Expanded dynamic range of fluorescent indicators for Ca(2+) by circularly permuted yellow fluorescent proteins.Q30769723
High-sensitivity vibrational imaging with frequency modulation coherent anti-Stokes Raman scattering (FM CARS) microscopyQ30816807
Genetically encoded reporters of protein kinase A activity reveal impact of substrate tetheringQ30857018
MALDI mass spectrometry imaging, from its origins up to today: the state of the art.Q30858032
Translating metabolic exchange with imaging mass spectrometryQ30885731
Molecular imaging in living subjects: seeing fundamental biological processes in a new lightQ35082602
Tracking N-acetyllactosamine on cell-surface glycans in vivoQ35105412
Imaging Zinc: Old and New ToolsQ35127305
Biomedical applications of tetrazine cycloadditionsQ35194732
A nuclear-localized fluorescent hydrogen peroxide probe for monitoring sirtuin-mediated oxidative stress responses in vivoQ35213603
Photoinducible bioorthogonal chemistry: a spatiotemporally controllable tool to visualize and perturb proteins in live cellsQ35218154
A chemical approach for identifying O-GlcNAc-modified proteins in cellsQ35242785
From mechanism to mouse: a tale of two bioorthogonal reactionsQ35252297
A chemical reporter strategy to probe glycoprotein fucosylationQ35599485
Dynamic metabolic labeling of DNA in vivo with arabinosyl nucleosidesQ35651069
Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells.Q35669639
Ligands for L-selectin: homing, inflammation, and beyondQ35698423
Multi-isotope imaging mass spectrometry quantifies stem cell division and metabolismQ35705767
Phospholipid biosynthesis in mammalian cellsQ35723447
Classifying human brain tumors by lipid imaging with mass spectrometryQ35729801
Near-infrared fluorescent sensor for in vivo copper imaging in a murine Wilson disease modelQ35787093
Role of glycosylation in developmentQ35799981
Polar dibenzocyclooctynes for selective labeling of extracellular glycoconjugates of living cellsQ35871298
Lectin-based structural glycomics: glycoproteomics and glycan profilingQ35910289
Intracellular detection of cytosine incorporation in genomic DNA by using 5-ethynyl-2'-deoxycytidine.Q35926356
Monitoring of lipid storage in Caenorhabditis elegans using coherent anti-Stokes Raman scattering (CARS) microscopyQ35990206
Reactivity of biarylazacyclooctynones in copper-free click chemistryQ36011672
Building and breeding molecules to spy on cells and tumorsQ36024283
Zinspy sensors with enhanced dynamic range for imaging neuronal cell zinc uptake and mobilizationQ36029781
Imaging the sialome during zebrafish development with copper-free click chemistryQ36065635
Designed to dissolve: suppression of colloidal aggregation of Cu(I)-selective fluorescent probes in aqueous buffer and in-gel detection of a metallochaperoneQ36073818
The neurobiology of zinc in health and diseaseQ36126098
Imaging phosphoinositide dynamics using GFP-tagged protein domainsQ36168511
Use of fluorescence probes for detection of reactive nitrogen species: a review.Q36396193
Recent advances in fluorescent probes for the detection of reactive oxygen speciesQ36446206
Live cell imaging of phosphoinositide dynamics with fluorescent protein domainsQ36479477
A chemical method for fast and sensitive detection of DNA synthesis in vivoQ36497275
New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structuresQ36628858
Structure of solid tumors and their vasculature: implications for therapy with monoclonal antibodiesQ36657134
Site-specific fluorescent labeling of DNA using Staudinger ligationQ30934851
Vibrational imaging of lipid droplets in live fibroblast cells with coherent anti-Stokes Raman scattering microscopyQ30976965
Picosecond-pulse amplification with an external passive optical cavityQ31003561
A smart magnetic resonance contrast agent for selective copper sensingQ31085165
Water-soluble porphyrins as a dual-function molecular imaging platform for MRI and fluorescence zinc sensing.Q31116256
Click chemistry to construct fluorescent oligonucleotides for DNA sequencingQ31126111
Nonresonant confocal Raman imaging of DNA and protein distribution in apoptotic cells.Q31143590
Direct tissue analysis of phospholipids in rat brain using MALDI-TOFMS and MALDI-ion mobility-TOFMS.Q31146503
In situ MALDI-TOF MS regional analysis of neutral phospholipids in lens tissueQ33199440
Subcellular imaging mass spectrometry of brain tissue.Q33211786
Visualizing the mechanical activation of Src.Q33214304
Optical molecular imaging of lymph nodes using a targeted vascular contrast agentQ33223798
QZ1 and QZ2: rapid, reversible quinoline-derivatized fluoresceins for sensing biological Zn(II)Q33228118
Oscillations of cyclic AMP in hormone-stimulated insulin-secreting beta-cellsQ33231962
Advances in fluorescent tracking of nucleic acids in living cellsQ33240612
Nonperturbative chemical imaging of organelle transport in living cells with coherent anti-stokes Raman scattering microscopyQ33240794
MALDI-based imaging mass spectrometry revealed abnormal distribution of phospholipids in colon cancer liver metastasisQ33279262
Measuring calcium signaling using genetically targetable fluorescent indicatorsQ33280954
Imaging mass spectrometry.Q33283309
Profiling and imaging of tissues by imaging ion mobility-mass spectrometryQ33290372
Metal-free triazole formation as a tool for bioconjugationQ33290867
MALDI imaging mass spectrometry: molecular snapshots of biochemical systemsQ33300677
Visualizing the spatial distribution of secondary metabolites produced by marine cyanobacteria and sponges via MALDI-TOF imagingQ33336616
Cluster TOF-SIMS imaging: a new light for in situ metabolomics?Q33361364
Chemical calcium indicatorsQ33377705
Advances in imaging secondary ion mass spectrometry for biological samplesQ33393363
Copper-responsive magnetic resonance imaging contrast agentsQ33458691
Scanning coherent anti-Stokes Raman microscopeQ33497747
Imaging chromophores with undetectable fluorescence by stimulated emission microscopyQ33511745
Rapid and selective detection of fatty acylated proteins using omega-alkynyl-fatty acids and click chemistryQ33520388
A palette of fluorescent probes with varying emission colors for imaging hydrogen peroxide signaling in living cellsQ33548893
In vivo imaging of Caenorhabditis elegans glycansQ33595565
High-efficiency labeling of sialylated glycoproteins on living cellsQ33694324
Highly sensitive near-infrared fluorescent probes for nitric oxide and their application to isolated organsQ46383263
A FRET-based approach to ratiometric fluorescence detection of hydrogen peroxideQ46402530
Imaging orientational order and lipid density in multilamellar vesicles with multiplex CARS microscopyQ46427264
Boron dipyrromethene fluorophore based fluorescence sensor for the selective imaging of Zn(II) in living cellsQ46435522
Lipid imaging by gold cluster time-of-flight secondary ion mass spectrometry: application to Duchenne muscular dystrophy.Q46440487
N-Myristoyl transferase-mediated protein labelling in vivoQ46532836
Nucleophilic catalysis of hydrazone formation and transimination: implications for dynamic covalent chemistryQ46677777
Site-specific N-terminal labelling of proteins in vitro and in vivo using N-myristoyl transferase and bioorthogonal ligation chemistry.Q46813310
Localization of cholesterol, phosphocholine and galactosylceramide in rat cerebellar cortex with imaging TOF-SIMS equipped with a bismuth cluster ion sourceQ46814560
A genetically encoded fluorescent reporter of histone phosphorylation in living cellsQ47412943
Fluorogenic and chromogenic rhodamine spirolactam based probe for nitric oxide by spiro ring opening reactionQ47702783
Monitoring of iron(III) removal from biological sources using a fluorescent siderophore.Q47850133
Metal-based turn-on fluorescent probes for sensing nitric oxideQ48417864
Single-spike detection in vitro and in vivo with a genetic Ca2+ sensorQ48798005
Development of a ratiometric fluorescent zinc ion probe in near-infrared region, based on tricarbocyanine chromophore.Q50734442
Highly sensitive and selective near-infrared fluorescent probe for zinc and its application to macrophage cells.Q51117329
Living cells as test tubes.Q51226543
Intracellular sorting of galectin-8 based on carbohydrate fine specificity.Q51796662
Glycan-specific metabolic oligosaccharide engineering of C7-substituted sialic acids.Q52887996
A Comparative Study of Bioorthogonal Reactions with AzidesQ54279492
Click-mediated labeling of bacterial membranes through metabolic modification of the lipopolysaccharide inner core.Q54342575
Detection and imaging of nitric oxide with novel fluorescent indicators: diaminofluoresceins.Q55067651
Chemically-selective imaging of brain structures with CARS microscopy.Q55467772
Über neue organische Phosphorverbindungen III. Phosphinmethylenderivate und PhosphinimineQ56431402
Photoreduction of the fluorescent dye 2'-7'-dichlorofluorescein: a spin trapping and direct electron spin resonance study with implications for oxidative stress measurementsQ57013381
The glycosylation of thymic microenvironmentsQ57261984
ToF-SIMS imaging of lipids in cell membranesQ57355791
Phospholipid signalling: mediators in need of interdisciplinary techniquesQ57355867
MALDI-TOF and cluster-TOF-SIMS imaging of Fabry disease biomarkersQ57360951
Lipid imaging in the zebra finch brain with secondary ion mass spectrometryQ57360955
A Genetically Encoded Norbornene Amino Acid for the Mild and Selective Modification of Proteins in a Copper-Free Click ReactionQ57376734
Three-Dimensional Vibrational Imaging by Coherent Anti-Stokes Raman ScatteringQ57534160
Strength in numbers: non-natural polyvalent carbohydrate derivativesQ60502325
A Cellular FRET-Based Sensor for β-O-GlcNAc, A Dynamic Carbohydrate Modification Involved in SignalingQ60901893
Controlled Nucleation of DNA MetallizationQ62577403
Evaluation of the probe 2',7'-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stressQ67493487
Dihydrorhodamine 123: a fluorescent probe for superoxide generation?Q72564098
A genetically encoded, fluorescent indicator for cyclic AMP in living cellsQ73323788
Measuring zinc in living cells. A new generation of sensitive and selective fluorescent probesQ74412790
Design and synthesis of a novel magnetic resonance imaging contrast agent for selective sensing of zinc ionQ77219905
Phosphoinositide lipids as signaling molecules: common themes for signal transduction, cytoskeletal regulation, and membrane traffickingQ77803407
Phase separation of lipid membranes analyzed with high-resolution secondary ion mass spectrometryQ79156856
Localization of lipids in the aortic wall with imaging TOF-SIMSQ79616454
Tunable design strategy for fluorescence probes based on 4-substituted BODIPY chromophore: improvement of highly sensitive fluorescence probe for nitric oxideQ80149486
Lectin microarrays for glycoprotein analysisQ80953416
Novel iron-specific fluorescent probesQ81838643
Genetically encoded fluorescent indicator for intracellular hydrogen peroxideQ82918322
A new rhodamine-based chemosensor exhibiting selective Fe(III)-amplified fluorescenceQ83098645
New fluorescent rhodamine hydrazone chemosensor for Cu(II) with high selectivity and sensitivityQ83992432
Optical measurement of synaptic glutamate spillover and reuptake by linker optimized glutamate-sensitive fluorescent reportersQ36670320
Lectins: carbohydrate-specific reagents and biological recognition moleculesQ36673623
A FRET-based fluorogenic phosphine for live-cell imaging with the Staudinger ligationQ36746471
Exploring RNA transcription and turnover in vivo by using click chemistryQ36948935
FRET-based biosensors for protein kinases: illuminating the kinomeQ36973316
Fluorescent probes for nitric oxide and hydrogen peroxide in cell signalingQ36984470
Imaging mass spectrometry in microbiologyQ37009407
A genetically encoded fluorescent sensor of ERK activityQ37039507
Live-cell imaging of cAMP dynamicsQ37047823
Imaging the glycomeQ37068279
New strategy for quantifying biological zinc by a modified zinpyr fluorescence sensorQ37105026
Metals in neurobiology: probing their chemistry and biology with molecular imaging.Q37143450
Postsynthetic DNA modification through the copper-catalyzed azide-alkyne cycloaddition reactionQ37278316
Measuring calcium dynamics in living cells with genetically encodable calcium indicatorsQ37291751
Fluorescent probes for live-cell RNA detectionQ37325999
Metabolic labeling and direct imaging of choline phospholipids in vivoQ37340822
Metabolic glycoengineering: sialic acid and beyondQ37405391
Label-free molecular imaging of living cellsQ37420742
Fluorescent biosensors for real-time tracking of post-translational modification dynamicsQ37580288
Chemical tools for understanding protein lipidation in eukaryotesQ37584384
Cellular imaging with secondary ion mass spectrometryQ37617059
Fluorescent protein-based biosensors: resolving spatiotemporal dynamics of signalingQ37632058
Visualization of DNA methylation and histone modifications in living cellsQ37703825
The chemical toolbox for monitoring protein fatty acylation and prenylationQ37766085
Chemical contrast for imaging living systems: molecular vibrations drive CARS microscopy.Q37842114
Coherent nonlinear optical imaging: beyond fluorescence microscopyQ37859767
Exploring protein lipidation with chemical biologyQ37932506
Mass spectrometric imaging of highly curved membranes during Tetrahymena mating.Q39441055
Determination of the chelatable iron pool of isolated rat hepatocytes by digital fluorescence microscopy using the fluorescent probe, phen green SK.Q39490128
Visualizing metabolically labeled glycoconjugates of living cells by copper-free and fast huisgen cycloadditions.Q39512277
Imaging sialylated tumor cell glycans in vivo.Q39558573
Bioorthogonal chemical tagging of protein cholesterylation in living cellsQ39609512
P433issue71
P407language of work or nameEnglishQ1860
P304page(s)8864-8879
P577publication date2012-07-17
P1433published inChemical CommunicationsQ426303
P1476titleImaging beyond the proteome
P478volume48

Reverse relations

cites work (P2860)
Q391480219-(4-Dimethylaminophenyl)benzo[b]quinolizinium: a near-infrared fluorophore for the multicolor analysis of proteins and nucleic acids in living cells
Q36029831A comprehensive review of glycosylated bacterial natural products.
Q57496291A new structure-activity relationship for cyanine dyes to improve photostability and fluorescence properties for live cell imaging
Q42643016A platform for designing hyperpolarized magnetic resonance chemical probes
Q51074988Alkynyl crown ethers as a scaffold for hyperconjugative assistance in noncatalyzed azide-alkyne click reactions: ion sensing through enhanced transition-state stabilization.
Q87470383An azide-modified nucleoside for metabolic labeling of DNA
Q40778293An injectable and fast-degradable poly(ethylene glycol) hydrogel fabricated via bioorthogonal strain-promoted azide-alkyne cycloaddition click chemistry
Q49926212Bright and photostable cyanine-styryl chromophores with green and red fluorescence colour for DNA staining
Q48134429Carbohydrate-Neuroactive Hybrid Strategy for Metabolic Glycan Engineering of the Central Nervous System in Vivo.
Q35602409Challenges and opportunities toward enabling phenotypic screening of complex and 3D cell models
Q87415113Click-chemistry tagging of proteins in living cells: new possibilities for microbial (meta) proteomics
Q57760848Colorimetric and Plasmonic Detection of Lectins Using Core–Shell Gold Glyconanoparticles Prepared by Copper-Free Click Chemistry
Q92738128Complementary Approaches to Imaging Subcellular Lipid Architectures in Live Bacteria Using Phosphorescent Iridium Complexes and Raman Spectroscopy
Q57801718Copper signalling: causes and consequences
Q39013589Cyanine-based fluorescent probe for highly selective detection of glutathione in cell cultures and live mouse tissues
Q45195249DNA and RNA "traffic lights": synthetic wavelength-shifting fluorescent probes based on nucleic acid base substitutes for molecular imaging
Q64263394Design strategy for serine hydroxymethyltransferase probes based on retro-aldol-type reaction
Q91690185Dual ligand co-functionalized fluorescent gold nanoclusters for the "turn on" sensing of glutathione in tumor cells
Q33820952Dual-Responsive Molecular Probe for Tumor Targeted Imaging and Photodynamic Therapy
Q39092098Dual-sugar imaging using isonitrile and azido-based click chemistries
Q55669010Exceptionally rapid oxime and hydrazone formation promoted by catalytic amine buffers with low toxicity.
Q38834367Exploring human glycosylation for better therapies
Q38089360Exterior design: strategies for redecorating the bacterial surface with small molecules
Q38179473Finding the right (bioorthogonal) chemistry.
Q62477264Fluorescent Sensors for the Detection of Heavy Metal Ions in Aqueous Media
Q57281471Fluorogenic "photoclick" labelling of DNA using a Cy3 dye
Q27027997Glycotherapy: new advances inspire a reemergence of glycans in medicine
Q48275160Green and Red Fluorescent Dyes for Translational Applications in Imaging and Sensing Analytes: A Dual-Color Flag.
Q42232118Identification of living Legionella pneumophila using species-specific metabolic lipopolysaccharide labeling
Q108767997Labelling of DNA and RNA in the cellular environment by means of bioorthogonal cycloaddition chemistry
Q48653370Light-induced functions in DNA.
Q38863114Metabolic Glyco-Engineering in Eukaryotic Cells and Selected Applications
Q51641823Naphthalimide-based fluorescent probe for selectively and specifically detecting glutathione in the lysosomes of living cells.
Q34992460New organocatalyst scaffolds with high activity in promoting hydrazone and oxime formation at neutral pH.
Q43949848Norbornenes in inverse electron-demand Diels-Alder reactions.
Q27339549One-step enzymatic modification of the cell surface redirects cellular cytotoxicity and parasite tropism
Q34688362Peptide Targeting of Fluorescein-Based Sensors to Discrete Intracellular Locales
Q37016458Peptide-based Targeting of Fluorescent Zinc Sensors to the Plasma Membrane of Live Cells
Q54284706Plasmonic imaging of protein interactions with single bacterial cells.
Q90350765Postsynthetic Modifications of DNA and RNA by Means of Copper-Free Cycloadditions as Bioorthogonal Reactions
Q36055646Progress and prospects for small-molecule probes of bacterial imaging
Q38570104Protein-specific imaging of posttranslational modifications
Q38904151Rapid probing of sialylated glycoproteins in vitro and in vivo via metabolic oligosaccharide engineering of a minimal cyclopropene reporter.
Q53712935Scope and Limitations of Typical Copper-Free Bioorthogonal Reactions with DNA: Reactive 2'-Deoxyuridine Triphosphates for Postsynthetic Labeling.
Q98563478Smart phone assisted quinoline-hemicyanine based fluorescent probe for the selective detection of glutathione and the application in living cells
Q53580953Stable and Rapid Thiol Bioconjugation by Light-Triggered Thiomaleimide Ring Hydrolysis.
Q50211659Strand displacement and duplex invasion into double-stranded DNA by pyrrolidinyl peptide nucleic acids
Q36642035Strategy for dual-analyte luciferin imaging: in vivo bioluminescence detection of hydrogen peroxide and caspase activity in a murine model of acute inflammation
Q46064767Structure-function relationships in glycopolymers: effects of residue sequences, duplex, and triplex organization
Q50495670Synthesis of 4-aminophthalimide and 2,4-diaminopyrimidine C-nucleosides as isosteric fluorescent DNA base substitutes
Q89174730Synthesis of Dye-Modified Oligonucleotides via Copper(I)-Catalyzed Alkyne Azide Cycloaddition Using On- and Off-Bead Approaches
Q41239481Synthesis of Wavelength-Shifting Fluorescent DNA and RNA with Two Photostable Cyanine-Styryl Dyes as the Base Surrogate Pair
Q36412554Systemic Fluorescence Imaging of Zebrafish Glycans with Bioorthogonal Chemistry
Q50466653The role of duplex stability for wavelength-shifting fluorescent DNA probes: energy transfer vs. exciton interactions in DNA "traffic lights".
Q48097783The versatility of N-alkyl-methoxyamine bi-functional linkers for the preparation of glycoconjugates
Q50235113Thiazole Orange Dimers in DNA: Fluorescent Base Substitutions with Hybridization Readout
Q33676201Tracking the subcellular fate of 20(s)-hydroxycholesterol with click chemistry reveals a transport pathway to the Golgi
Q50202498Two wavelength-shifting molecular beacons for simultaneous and selective imaging of vesicular miRNA-21 and miRNA-31 in living cancer cells

Search more.