| scholarly article | Q13442814 |
| P50 | author | Hans Clevers | Q1579050 |
| Reuven Agami | Q30502648 | ||
| Marc van de Wetering | Q42800469 | ||
| P2093 | author name string | Irma Oving | |
| Thijn R Brummelkamp | |||
| Frank C P Holstege | |||
| Vanesa Muncan | |||
| Dik van Leenen | |||
| Helen Brantjes | |||
| Menno Tjon Pon Fong | |||
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| Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC | Q24336321 | ||
| Tight control of gene expression in mammalian cells by tetracycline-responsive promoters | Q24564850 | ||
| A system for stable expression of short interfering RNAs in mammalian cells | Q27860875 | ||
| Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells | Q27860926 | ||
| Lessons from hereditary colorectal cancer | Q28131788 | ||
| 14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage | Q28145962 | ||
| Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells | Q28215061 | ||
| Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB | Q28508041 | ||
| A DNA vector-based RNAi technology to suppress gene expression in mammalian cells | Q29616551 | ||
| Linking colorectal cancer to Wnt signaling | Q29619810 | ||
| RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells | Q30476196 | ||
| Targeted inactivation of CTNNB1 reveals unexpected effects of beta-catenin mutation | Q34032260 | ||
| RNA interference--2001. | Q34174586 | ||
| Monitoring global messenger RNA changes in externally controlled microarray experiments. | Q34236555 | ||
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| Mammalian RNAi for the masses | Q35031139 | ||
| An unusually compact external promoter for RNA polymerase III transcription of the human H1RNA gene | Q39094983 | ||
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| Effective expression of small interfering RNA in human cells | Q40735246 | ||
| Mutant E-cadherin breast cancer cells do not display constitutive Wnt signaling. | Q40825662 | ||
| Tetracycline Repressor, tetR, rather than the tetR–Mammalian Cell Transcription Factor Fusion Derivatives, Regulates Inducible Gene Expression in Mammalian Cells | Q41008242 | ||
| Altered growth of human colon cancer cell lines disrupted at activated Ki-ras | Q42810367 | ||
| U6 promoter-driven siRNAs with four uridine 3' overhangs efficiently suppress targeted gene expression in mammalian cells. | Q43974693 | ||
| Control of the functional activity of an antisense RNA by a tetracycline-responsive derivative of the human U6 snRNA promoter | Q45866094 | ||
| Proof-of-principle: oncogenic beta-catenin is a valid molecular target for the development of pharmacological inhibitors | Q78760398 | ||
| P433 | issue | 6 | |
| P304 | page(s) | 609-615 | |
| P577 | publication date | 2003-06-01 | |
| P1433 | published in | EMBO Reports | Q5323356 |
| P1476 | title | Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector | |
| P478 | volume | 4 |
| Q38757495 | A Nexus Consisting of Beta-Catenin and Stat3 Attenuates BRAF Inhibitor Efficacy and Mediates Acquired Resistance to Vemurafenib |
| Q28245051 | A Rac1/PAK1 cascade controls β-catenin activation in colon cancer cells |
| Q27301472 | A cryptic frizzled module in cell surface collagen 18 inhibits Wnt/beta-catenin signaling |
| Q24302377 | A diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells |
| Q33472881 | A dual-fluorescence high-throughput cell line system for probing multidrug resistance |
| Q40169109 | A facile lentiviral vector system for expression of doxycycline-inducible shRNAs: knockdown of the pre-miRNA processing enzyme Drosha |
| Q35881172 | A kinome siRNA screen identifies HGS as a potential target for liver cancers with oncogenic mutations in CTNNB1. |
| Q33240316 | A library of gene expression signatures to illuminate normal and pathological lymphoid biology |
| Q33237976 | A loss-of-function RNA interference screen for molecular targets in cancer |
| Q40110405 | A more efficient RNAi inducible system for tight regulation of gene expression in mammalian cells and xenograft animals |
| Q83964376 | A new inducible RNAi xenograft model for assessing the staged tumor response to mTOR silencing |
| Q54663468 | A novel conditional gene silencing method using a tumor-specific and heat-inducible siRNA system. |
| Q36545417 | A novel gammaretroviral shuttle vector insertional mutagenesis screen identifies SHARPIN as a breast cancer metastasis gene and prognostic biomarker |
| Q40102629 | A retroviral vector for siRNA expression in mammalian cells |
| Q58590438 | A simple approach for multi-targeted shRNA-mediated inducible knockdowns using Sleeping Beauty vectors |
| Q41337955 | A universal transgene silencing method based on RNA interference |
| Q28475909 | A versatile viral system for expression and depletion of proteins in mammalian cells |
| Q34438021 | AF6 negatively regulates Rap1-induced cell adhesion |
| Q24651305 | AP-2gamma promotes proliferation in breast tumour cells by direct repression of the CDKN1A gene |
| Q24329154 | APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process. |
| Q24650473 | APE1/Ref-1 regulates PTEN expression mediated by Egr-1 |
| Q40280621 | AU-rich elements and alternative splicing in the beta-catenin 3'UTR can influence the human beta-catenin mRNA stability |
| Q34350571 | AV-65, a novel Wnt/β-catenin signal inhibitor, successfully suppresses progression of multiple myeloma in a mouse model |
| Q37527117 | Alix/AIP1 antagonizes epidermal growth factor receptor downregulation by the Cbl-SETA/CIN85 complex. |
| Q44939765 | An inducible T7 RNA polymerase-dependent plasmid system |
| Q39816458 | Analysis of human cytomegalovirus-encoded microRNA activity during infection |
| Q24298407 | Analysis of orthologous groups reveals archease and DDX1 as tRNA splicing factors |
| Q34019804 | Annexin A2 Binds RNA and Reduces the Frameshifting Efficiency of Infectious Bronchitis Virus |
| Q34371320 | Antiviral effects of human immunodeficiency virus type 1-specific small interfering RNAs against targets conserved in select neurotropic viral strains |
| Q40219908 | Apoptosis and erythroid differentiation triggered by Bcr-Abl inhibitors in CML cell lines are fully distinguishable processes that exhibit different sensitivity to caspase inhibition. |
| Q36274423 | Approaches for chemically synthesized siRNA and vector-mediated RNAi |
| Q21195230 | Autocrine WNT signaling contributes to breast cancer cell proliferation via the canonical WNT pathway and EGFR transactivation |
| Q24298234 | Bcr-Abl stabilizes beta-catenin in chronic myeloid leukemia through its tyrosine phosphorylation |
| Q40092823 | Beta-catenin binds to the downstream region and regulates the expression C-reactive protein gene |
| Q80265621 | Bilirubin-induced cell toxicity involves PTEN activation through an APE1/Ref-1-dependent pathway |
| Q24336306 | CCAR1, a key regulator of mediator complex recruitment to nuclear receptor transcription complexes |
| Q28565835 | CLIP-170 and IQGAP1 cooperatively regulate dendrite morphology |
| Q24321723 | Carboxy-Terminal Modulator Protein (CTMP) is a mitochondrial protein that sensitizes cells to apoptosis |
| Q24535324 | Cell cycle-regulated inactivation of endothelial NO synthase through NOSIP-dependent targeting to the cytoskeleton |
| Q33532273 | Cellular toxicity following application of adeno-associated viral vector-mediated RNA interference in the nervous system |
| Q35841926 | Central chondrosarcoma progression is associated with pRb pathway alterations: CDK4 down-regulation and p16 overexpression inhibit cell growth in vitro |
| Q24685209 | Cingulin regulates claudin-2 expression and cell proliferation through the small GTPase RhoA |
| Q33434409 | Clusters of basic amino acids contribute to RNA binding and nucleolar localization of ribosomal protein L22 |
| Q40147212 | Comparison of RNAi efficiency mediated by tetracycline-responsive H1 and U6 promoter variants in mammalian cell lines |
| Q34546258 | Complete polarization of single intestinal epithelial cells upon activation of LKB1 by STRAD. |
| Q37779599 | Conditional RNAi in mice. |
| Q40098950 | Conditional gene knock-down by CRE-dependent short interfering RNAs |
| Q44887884 | Conditional gene silencing utilizing the lac repressor reveals a role of SHP-2 in cagA-positive Helicobacter pylori pathogenicity |
| Q28118613 | Conditional knockdown of hMRS2 results in loss of mitochondrial Mg(2+) uptake and cell death |
| Q51892678 | Constitutive and conditional RNAi transgenesis in mice |
| Q28253107 | Construction of permanently inducible miRNA-based expression vectors using site-specific recombinases |
| Q33833394 | Control of siRNA expression using the Cre-loxP recombination system. |
| Q24542892 | Control of small inhibitory RNA levels and RNA interference by doxycycline induced activation of a minimal RNA polymerase III promoter |
| Q26851275 | Crosstalk between Wnt/β-catenin and Hedgehog/Gli signaling pathways in colon cancer and implications for therapy |
| Q39995485 | Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling |
| Q42283989 | Cytoplasmic interaction of the tumour suppressor protein hSNF5 with dynamin-2 controls endocytosis |
| Q40105893 | Cytotoxic drug-induced, p53-mediated upregulation of caspase-8 in tumor cells |
| Q33987511 | DEC1, a basic helix-loop-helix transcription factor and a novel target gene of the p53 family, mediates p53-dependent premature senescence |
| Q34353609 | DNA polymerase eta, the product of the xeroderma pigmentosum variant gene and a target of p53, modulates the DNA damage checkpoint and p53 activation. |
| Q35894395 | Deciphering the renal code: advances in conditional gene targeting |
| Q34391473 | Deep sequencing reveals complex spurious transcription from transiently transfected plasmids |
| Q33505682 | Designer siRNAs to overcome the challenges from the RNAi pathway. |
| Q40489589 | Development of a tightly regulated U6 promoter for shRNA expression |
| Q28476623 | Development of an All-in-One Lentiviral Vector System Based on the Original TetR for the Easy Generation of Tet-ON Cell Lines |
| Q41916004 | Different Plk1 functions show distinct dependencies on Polo-Box domain-mediated targeting |
| Q83234334 | Differential effect of exocytic SNAREs on the production of recombinant proteins in mammalian cells |
| Q24631220 | Divergent susceptibilities of human herpesvirus 6 variants to type I interferons |
| Q39971495 | Downregulation of the Spi-1/PU.1 oncogene induces the expression of TRIM10/HERF1, a key factor required for terminal erythroid cell differentiation and survival |
| Q40749737 | Downregulation of the stress-induced ligand ULBP1 following SV40 infection confers viral evasion from NK cell cytotoxicity |
| Q35128043 | Effects of Dicer and Argonaute down-regulation on mRNA levels in human HEK293 cells |
| Q33770079 | Efficient double fragmentation ChIP-seq provides nucleotide resolution protein-DNA binding profiles |
| Q36054237 | Endoglin promotes TGF-β/Smad1 signaling in scleroderma fibroblasts |
| Q36169056 | Epigenetic manipulation of gene expression: a toolkit for cell biologists |
| Q38844095 | Evidence that the endosomal sorting complex required for transport-II (ESCRT-II) is required for efficient human immunodeficiency virus-1 (HIV-1) production |
| Q39306326 | Expression of endogenous retroviruses is negatively regulated by the pluripotency marker Rex1/Zfp42. |
| Q44819303 | Expression of shRNA from a tissue-specific pol II promoter is an effective and safe RNAi therapeutic |
| Q33741883 | Extensive localization of long noncoding RNAs to the cytosol and mono- and polyribosomal complexes |
| Q80139816 | FGFs, Wnts and BMPs mediate induction of VEGFR-2 (Quek-1) expression during avian somite development |
| Q30444216 | Focal adhesions are hotspots for keratin filament precursor formation |
| Q39026147 | FoxM1c counteracts oxidative stress-induced senescence and stimulates Bmi-1 expression. |
| Q28294595 | GPX2, a direct target of p63, inhibits oxidative stress-induced apoptosis in a p53-dependent manner |
| Q39669007 | Gene knockdown in the mouse through RNAi. |
| Q39819083 | Gene knockdown studies revealed CCDC50 as a candidate gene in mantle cell lymphoma and chronic lymphocytic leukemia. |
| Q43874355 | Gene silencing in adult rat cardiac myocytes in vitro by adenovirus-mediated RNA interference |
| Q36091296 | Gene therapy progress and prospects: recent progress in transgene and RNAi expression cassettes |
| Q35676294 | Gene therapy progress and prospects: transcription regulatory systems. |
| Q39474732 | Generation of Inducible shRNAi Human Embryonic Stem Cell Lines |
| Q33261158 | Generation of RNAi libraries for high-throughput screens |
| Q39181585 | Generation of stable human cell lines with Tetracycline-inducible (Tet-on) shRNA or cDNA expression |
| Q24299046 | Genome instability and transcription elongation impairment in human cells depleted of THO/TREX |
| Q37242539 | Genome-wide analysis and proteomic studies reveal APE1/Ref-1 multifunctional role in mammalian cells. |
| Q36540321 | Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells |
| Q39618195 | Genome-wide shRNA screen reveals increased mitochondrial dependence upon mTORC2 addiction |
| Q37608829 | Glycerophosphoglycerol, Beta-alanine, and pantothenic Acid as metabolic companions of glycolytic activity and cell migration in breast cancer cell lines. |
| Q35971454 | Glycogen Synthesis is Induced in Hypoxia by the Hypoxia-Inducible Factor and Promotes Cancer Cell Survival |
| Q38311623 | Glyoxalase II, a detoxifying enzyme of glycolysis byproduct methylglyoxal and a target of p63 and p73, is a pro-survival factor of the p53 family |
| Q37355983 | Growth-promoting properties of Epstein-Barr virus EBER-1 RNA correlate with ribosomal protein L22 binding |
| Q39385114 | HSV-2 specifically down regulates HLA-C expression to render HSV-2-infected DCs susceptible to NK cell killing |
| Q35049311 | High-frequency canonical Wnt activation in multiple sarcoma subtypes drives proliferation through a TCF/β-catenin target gene, CDC25A. |
| Q33838425 | Human Cdc14B promotes progression through mitosis by dephosphorylating Cdc25 and regulating Cdk1/cyclin B activity |
| Q36481765 | Human SMC2 protein, a core subunit of human condensin complex, is a novel transcriptional target of the WNT signaling pathway and a new therapeutic target. |
| Q28114920 | Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains |
| Q39216025 | Identification of KAP-1-associated complexes negatively regulating the Ey and β-major globin genes in the β-globin locus |
| Q22242847 | Identification of functional microRNAs released through asymmetrical processing of HIV-1 TAR element |
| Q33256754 | Identification of genes regulated by Wnt/beta-catenin pathway and involved in apoptosis via microarray analysis |
| Q40121209 | Improving miRNA Delivery by Optimizing miRNA Expression Cassettes in Diverse Virus Vectors |
| Q35773259 | Improving the efficiency of RNA interference in mammals |
| Q42854188 | In vitro epithelial-to-mesenchymal transformation in human adult epicardial cells is regulated by TGFβ-signaling and WT1 |
| Q42941339 | In vivo analysis of gene knockdown in tetracycline-inducible shRNA mice. |
| Q37225885 | Inactivation of CDK2 is synthetically lethal to MYCN over-expressing cancer cells |
| Q36985023 | Inducible and reversible gene silencing by stable integration of an shRNA-encoding lentivirus in transgenic rats |
| Q30826808 | Inducible microRNA expression by an all-in-one episomal vector system |
| Q40240530 | Inducible shRNA expression for application in a prostate cancer mouse model |
| Q36604113 | Inducible, reversible, and stable RNA interference in mammalian cells |
| Q35131723 | Inhibiting the mitochondrial fission machinery does not prevent Bax/Bak-dependent apoptosis. |
| Q41015064 | Inhibition of AGS Cancer Cell Proliferation following siRNA-Mediated Downregulation of VEGFR2. |
| Q34429613 | Inhibition of Tcf-4 Induces Apoptosis and Enhances Chemosensitivity of Colon Cancer Cells |
| Q45054541 | Inhibition of glycogen synthase kinase-3 represses androgen receptor activity and prostate cancer cell growth |
| Q34531744 | Inhibition of viruses by RNA interference |
| Q39474443 | Integrated genome-wide analysis of transcription factor occupancy, RNA polymerase II binding and steady-state RNA levels identify differentially regulated functional gene classes |
| Q28283184 | Interaction between beta-catenin and HIF-1 promotes cellular adaptation to hypoxia |
| Q36868512 | Intronically encoded siRNAs improve dynamic range of mammalian gene regulation systems and toggle switch |
| Q33748042 | Kaposi sarcoma-associated herpesvirus latency-associated nuclear antigen inhibits interferon (IFN) beta expression by competing with IFN regulatory factor-3 for binding to IFNB promoter |
| Q37191933 | Kaposi's sarcoma-associated herpesvirus K-bZIP protein is necessary for lytic viral gene expression, DNA replication, and virion production in primary effusion lymphoma cell lines |
| Q40097772 | Kinetochore dynein generates a poleward pulling force to facilitate congression and full chromosome alignment |
| Q24797399 | Knockdown of c-Myc expression by RNAi inhibits MCF-7 breast tumor cells growth in vitro and in vivo |
| Q36321410 | L1, a novel target of beta-catenin signaling, transforms cells and is expressed at the invasive front of colon cancers |
| Q43133843 | LIP5 interacts with aquaporin 2 and facilitates its lysosomal degradation |
| Q40313768 | Large-scale, high-throughput validation of short hairpin RNA sequences for RNA interference |
| Q33291003 | Lentiviral vectors encoding tetracycline-dependent repressors and transactivators for reversible knockdown of gene expression: a comparative study |
| Q24303581 | Loss of HAUSP-mediated deubiquitination contributes to DNA damage-induced destabilization of Hdmx and Hdm2 |
| Q42278267 | Loss of programmed cell death 4 induces apoptosis by promoting the translation of procaspase-3 mRNA |
| Q38398531 | Lowering Endogenous Cathepsin D Abundance Results in Reactive Oxygen Species Accumulation and Cell Senescence |
| Q37164549 | MUC4 is negatively regulated through the Wnt/β-catenin pathway via the Notch effector Hath1 in colorectal cancer |
| Q53132207 | MYCN-mediated overexpression of mitotic spindle regulatory genes and loss of p53-p21 function jointly support the survival of tetraploid neuroblastoma cells |
| Q35345071 | Maintenance of adenomatous polyposis coli (APC)-mutant colorectal cancer is dependent on Wnt/beta-catenin signaling. |
| Q36216334 | Mammalian target of rapamycin complex 1 (mTORC1) and 2 (mTORC2) control the dendritic arbor morphology of hippocampal neurons |
| Q39013582 | Melanosome-autonomous regulation of size and number: the OA1 receptor sustains PMEL expression |
| Q39923613 | MiTF regulates cellular response to reactive oxygen species through transcriptional regulation of APE-1/Ref-1 |
| Q36116268 | MicroRNAs and Cancer Therapeutics |
| Q40072616 | Mitochondrial thymidine kinase and the enzymatic network regulating thymidine triphosphate pools in cultured human cells |
| Q81154564 | Modeling human disease by gene targeting |
| Q36748510 | Modeling inflammatory bowel disease: the zebrafish as a way forward. |
| Q38725125 | Modulation of GLO1 Expression Affects Malignant Properties of Cells. |
| Q38953543 | Molecular pathways driving disease-specific alterations of intestinal epithelial cells |
| Q37238133 | Mucins and Wnt/β-catenin signaling in gastrointestinal cancers: an unholy nexus |
| Q36663495 | Myeloid ecotropic viral integration site 1 (MEIS) 1 involvement in embryonic implantation |
| Q39886738 | Myocardin-related transcription factors and SRF are required for cytoskeletal dynamics and experimental metastasis |
| Q24306104 | Myosin VI is a mediator of the p53-dependent cell survival pathway. |
| Q46283330 | N-terminal PDZ-like domain of chromatin organizer SATB1 contributes towards its function as transcription regulator. |
| Q44358015 | Negative feedback inhibition of HIV-1 by TAT-inducible expression of siRNA. |
| Q27324745 | Non-Darwinian dynamics in therapy-induced cancer drug resistance |
| Q39111299 | Novel WWP2 ubiquitin ligase isoforms as potential prognostic markers and molecular targets in cancer |
| Q34519910 | Novel cross talk of Kruppel-like factor 4 and beta-catenin regulates normal intestinal homeostasis and tumor repression |
| Q35604698 | Nucleolin Maintains Embryonic Stem Cell Self-renewal by Suppression of p53 Protein-dependent Pathway |
| Q24540219 | Nudel contributes to microtubule anchoring at the mother centriole and is involved in both dynein-dependent and -independent centrosomal protein assembly |
| Q36137817 | Nudel is crucial for the WAVE complex assembly in vivo by selectively promoting subcomplex stability and formation through direct interactions |
| Q30479787 | Nudel modulates kinetochore association and function of cytoplasmic dynein in M phase |
| Q36316859 | On the delivery of small interfering RNAs into mammalian cells |
| Q35728858 | Optimizing RNA interference for application in mammalian cells |
| Q37372268 | PARP1 poly(ADP-ribosyl)ates Sox2 to control Sox2 protein levels and FGF4 expression during embryonic stem cell differentiation |
| Q94948335 | PRMT1 promotes neuroblastoma cell survival through ATF5 |
| Q36540331 | Phosphoinositide 3-kinases p110alpha and p110beta regulate cell cycle entry, exhibiting distinct activation kinetics in G1 phase |
| Q36276942 | Pim kinases modulate resistance to FLT3 tyrosine kinase inhibitors in FLT3-ITD acute myeloid leukemia |
| Q39224411 | Potent microRNA suppression by RNA Pol II-transcribed 'Tough Decoy' inhibitors |
| Q36429400 | Potential applications of RNA interference technology in the treatment of cancer |
| Q28552002 | Prion Protein Deficiency Causes Diverse Proteome Shifts in Cell Models That Escape Detection in Brain Tissue |
| Q28275174 | Probing tumor phenotypes using stable and regulated synthetic microRNA precursors |
| Q92352941 | Production of seedable Amyloid-β peptides in model of prion diseases upon PrPSc-induced PDK1 overactivation |
| Q36565686 | Promises and challenges in developing RNAi as a research tool and therapy for neurodegenerative diseases |
| Q36337922 | Prospects of RNA interference therapy for cancer |
| Q34000532 | Protein interaction screening by quantitative immunoprecipitation combined with knockdown (QUICK). |
| Q37082792 | Protein kinase G as a therapeutic target for the treatment of metastatic colorectal cancer |
| Q34146415 | Quantitative analysis of conditional gene inactivation using rationally designed, tetracycline-controlled miRNAs |
| Q45883640 | Quorum-sensing-based toolbox for regulatable transgene and siRNA expression in mammalian cells |
| Q24669950 | R-Etodolac decreases beta-catenin levels along with survival and proliferation of hepatoma cells |
| Q34628925 | RHOA inactivation enhances Wnt signalling and promotes colorectal cancer. |
| Q24675915 | RINT-1 serves as a tumor suppressor and maintains Golgi dynamics and centrosome integrity for cell survival |
| Q35563847 | RNA interference and human disease |
| Q34729434 | RNA interference for improving the outcome of islet transplantation |
| Q36618289 | RNA interference in pain research |
| Q36076736 | RNA interference technologies for understanding and treating neurodegenerative diseases |
| Q36440302 | RNA interference: its use as antiviral therapy. |
| Q36311494 | RNA interference: ready to silence cancer? |
| Q42831128 | RNA interfering approach for clarifying the PPARgamma pathway using lentiviral vector expressing short hairpin RNA. |
| Q37406048 | RNA polymerase III can drive polycistronic expression of functional interfering RNAs designed to resemble microRNAs |
| Q36631553 | RNA-mediated gene silencing in hematopoietic cells |
| Q40456936 | RNAi technology and lentiviral delivery as a powerful tool to suppress Tpr-Met-mediated tumorigenesis. |
| Q35633404 | RNAi-based conditional gene knockdown in mice using a U6 promoter driven vector |
| Q24307571 | RNPC1, an RNA-binding protein and a target of the p53 family, is required for maintaining the stability of the basal and stress-induced p21 transcript |
| Q35072549 | Rab GTPase prenylation hierarchy and its potential role in choroideremia disease |
| Q36994758 | Ras is required for the cyclic AMP-dependent activation of Rap1 via Epac2 |
| Q34771336 | Regulation of DNA damage responses and cell cycle progression by hMOB2. |
| Q24297305 | Regulation of NDR protein kinase by hydrophobic motif phosphorylation mediated by the mammalian Ste20-like kinase MST3 |
| Q34033913 | Regulation of human Dicer by the resident ER membrane protein CLIMP-63 |
| Q64094156 | Regulation of senescence escape by TSP1 and CD47 following chemotherapy treatment |
| Q37521220 | Reporters transiently transfected into mammalian cells are highly sensitive to translational repression induced by dsRNA expression |
| Q35804666 | Reversible gene knockdown in mice using a tight, inducible shRNA expression system |
| Q40066661 | Role for KAP1 serine 824 phosphorylation and sumoylation/desumoylation switch in regulating KAP1-mediated transcriptional repression |
| Q28260340 | Role of ALADIN in human adrenocortical cells for oxidative stress response and steroidogenesis |
| Q35105992 | Role of Brg1 and HDAC2 in GR trans-repression of the pituitary POMC gene and misexpression in Cushing disease. |
| Q39742276 | Role of Mdm4 in drug sensitivity of breast cancer cells |
| Q24302235 | Roles for the human ATP-dependent Lon protease in mitochondrial DNA maintenance |
| Q28591309 | SADB phosphorylation of gamma-tubulin regulates centrosome duplication |
| Q35502848 | SIRT3, a mitochondrial NAD⁺-dependent deacetylase, is involved in the regulation of myoblast differentiation |
| Q34628253 | SPFH2 mediates the endoplasmic reticulum-associated degradation of inositol 1,4,5-trisphosphate receptors and other substrates in mammalian cells |
| Q24307960 | SUMOylation of the transcriptional co-repressor KAP1 is regulated by the serine and threonine phosphatase PP1 |
| Q24319970 | Secreted Frizzled-related protein-1 is a negative regulator of androgen receptor activity in prostate cancer |
| Q38313243 | Securin (hPTTG1) expression is regulated by beta-catenin/TCF in human colorectal carcinoma |
| Q34303100 | Short Hairpin RNA-Mediated Gene Silencing |
| Q34586245 | Silencing mutated β-catenin inhibits cell proliferation and stimulates apoptosis in the adrenocortical cancer cell line H295R. |
| Q39322560 | Silencing of a large microRNA cluster on human chromosome 14q32 in melanoma: biological effects of mir-376a and mir-376c on insulin growth factor 1 receptor |
| Q46850564 | Silencing of mammalian genes by tetracycline-inducible shRNA expression |
| Q58164852 | Silencing the MET oncogene leads to regression of experimental tumors and metastases |
| Q38358218 | Similar regulation of human inducible nitric-oxide synthase expression by different isoforms of the RNA-binding protein AUF1. |
| Q24797255 | Single copy shRNA configuration for ubiquitous gene knockdown in mice |
| Q47137087 | Sirt1 interaction with active Smad2 modulates transforming growth factor-β regulated transcription. |
| Q34477634 | Smad3-dependent nuclear translocation of beta-catenin is required for TGF-beta1-induced proliferation of bone marrow-derived adult human mesenchymal stem cells |
| Q30476201 | Smad4 dependency defines two classes of transforming growth factor {beta} (TGF-{beta}) target genes and distinguishes TGF-{beta}-induced epithelial-mesenchymal transition from its antiproliferative and migratory responses |
| Q35571567 | Small RNA: can RNA interference be exploited for therapy? |
| Q40026760 | Small interfering RNA-mediated silencing of glutathione-S-transferase A1 sensitizes hepatic carcinoma cells to photodynamic therapy with pentaphyrins |
| Q36117036 | Smurf1 regulates tumor cell plasticity and motility through degradation of RhoA leading to localized inhibition of contractility |
| Q37183054 | Specific function of phosphoinositide 3-kinase beta in the control of DNA replication |
| Q39842651 | Specific knockdown of OCT4 in human embryonic stem cells by inducible short hairpin RNA interference. |
| Q33685166 | Spermatogenesis rescue in a mouse deficient for the ubiquitin ligase SCF{beta}-TrCP by single substrate depletion |
| Q36638098 | Sprouty2, PTEN, and PP2A interact to regulate prostate cancer progression |
| Q25256985 | Stable silencing of SNAP-25 in PC12 cells by RNA interference |
| Q37840092 | Strategies for tumor-directed delivery of siRNA |
| Q39941908 | Syntaxin 6, a regulator of the protein trafficking machinery and a target of the p53 family, is required for cell adhesion and survival |
| Q36254868 | Synthetic Tet-inducible artificial microRNAs targeting β-catenin or HIF-1α inhibit malignant phenotypes of bladder cancer cells T24 and 5637. |
| Q42775674 | TNF-related apoptosis-inducing ligand cooperates with NSAIDs via activated Wnt signalling in (pre)malignant colon cells. |
| Q90395944 | TRPM7-mediated spontaneous Ca2+ entry regulates the proliferation and differentiation of human leukemia cell line K562 |
| Q34415431 | Tandem affinity purification combined with inducible shRNA expression as a tool to study the maturation of macromolecular assemblies |
| Q25256814 | Targeted silencing of Jab1/Csn5 in human cells downregulates SCF activity through reduction of F-box protein levels |
| Q38104340 | Tetracycline regulated systems in functional oncogenomics |
| Q33440639 | The Carboxy-Terminal Modulator Protein (CTMP) regulates mitochondrial dynamics |
| Q38836796 | The E3 ligase RNF43 inhibits Wnt signaling downstream of mutated β-catenin by sequestering TCF4 to the nuclear membrane |
| Q24294942 | The Forkhead box M1 protein regulates the transcription of the estrogen receptor alpha in breast cancer cells |
| Q36127086 | The Krüppel-associated box repressor domain can induce reversible heterochromatization of a mouse locus in vivo. |
| Q51594081 | The STAT3 transcription factor is a target for the Myc and riboblastoma proteins on the Cdc25A promoter |
| Q24336893 | The SWI/SNF chromatin-remodeling complex is a cofactor for Tat transactivation of the HIV promoter |
| Q24313017 | The USP7/Dnmt1 complex stimulates the DNA methylation activity of Dnmt1 and regulates the stability of UHRF1 |
| Q37811369 | The Wnt/beta-catenin pathway in adrenocortical development and cancer |
| Q39457360 | The asparaginyl hydroxylase factor-inhibiting HIF is essential for tumor growth through suppression of the p53-p21 axis |
| Q35709058 | The c-MYC oncoprotein, the NAMPT enzyme, the SIRT1-inhibitor DBC1, and the SIRT1 deacetylase form a positive feedback loop |
| Q36535617 | The canonical Wnt signalling pathway and its APC partner in colon cancer development |
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