| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2011PNAS..10817135S |
| P356 | DOI | 10.1073/PNAS.1104182108 |
| P932 | PMC publication ID | 3193196 |
| P698 | PubMed publication ID | 21949247 |
| P5875 | ResearchGate publication ID | 51665273 |
| P50 | author | Dmitriy Sonkin | Q58396693 |
| P2093 | author name string | Frank Stegmeier | |
| William R Sellers | |||
| Michael R Schlabach | |||
| Yung-Mae Yao | |||
| Robert Schlegel | |||
| Alice Loo | |||
| Markus Warmuth | |||
| Steve Woolfenden | |||
| Alix Scholer-Dahirel | |||
| Linda Bagdasarian | |||
| Margaret E McLaughlin | |||
| Ribo Guo | |||
| Judit Markovits | |||
| Ronald Meyer | |||
| Kristine K Yu | |||
| Karen Killary | |||
| Rebecca E Mosher | |||
| P2860 | cites work | Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signalling | Q24290355 |
| Loss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosis | Q24293237 | ||
| Identification of c-MYC as a target of the APC pathway | Q24310637 | ||
| The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells | Q24314491 | ||
| Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma | Q24336272 | ||
| Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC | Q24336321 | ||
| Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene | Q24529898 | ||
| A genetic model for colorectal tumorigenesis | Q27860582 | ||
| Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells | Q27860717 | ||
| Identification of stem cells in small intestine and colon by marker gene Lgr5 | Q28131701 | ||
| Myc represses differentiation-induced p21CIP1 expression via Miz-1-dependent interaction with the p21 core promoter | Q28204860 | ||
| APC mutations occur early during colorectal tumorigenesis | Q28274764 | ||
| A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse | Q29616489 | ||
| Targeting PI3K signalling in cancer: opportunities, challenges and limitations | Q29617685 | ||
| Stabilization of beta-catenin by genetic defects in melanoma cell lines | Q29620190 | ||
| Targeted inactivation of CTNNB1 reveals unexpected effects of beta-catenin mutation | Q34032260 | ||
| Coordinating cell proliferation and differentiation | Q34132852 | ||
| Small interfering RNAs directed against beta-catenin inhibit the in vitro and in vivo growth of colon cancer cells | Q34189399 | ||
| Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer. | Q34461429 | ||
| Casein kinase 1: a Wnt'er of disconnect | Q34784729 | ||
| A Tetraspan Membrane Glycoprotein Produced in the Human Intestinal Epithelium and Liver That Can Regulate Cell Density-dependent Proliferation | Q36693577 | ||
| The role of autophagy in mammalian development: cell makeover rather than cell death | Q37208353 | ||
| Single-vector inducible lentiviral RNAi system for oncology target validation | Q39889810 | ||
| Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector | Q40773079 | ||
| Role of gut-enriched Krüppel-like factor in colonic cell growth and differentiation | Q40852596 | ||
| Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene. | Q54558350 | ||
| Detection of point mutations of the Axin1 gene in colorectal cancers | Q54748149 | ||
| Colorectal Tumors Are Effectively Eradicated by Combined Inhibition of -Catenin, KRAS, and the Oncogenic Transcription Factor ITF2 | Q57748874 | ||
| Differential apomucin expression in normal and neoplastic human gastrointestinal tissues | Q72036035 | ||
| Beta-catenin mutations are more frequent in small colorectal adenomas than in larger adenomas and invasive carcinomas | Q77304024 | ||
| P433 | issue | 41 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | colorectal cancer | Q188874 |
| polyposis | Q2103081 | ||
| colorectal carcinoma | Q25493920 | ||
| P304 | page(s) | 17135-17140 | |
| P577 | publication date | 2011-09-23 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Maintenance of adenomatous polyposis coli (APC)-mutant colorectal cancer is dependent on Wnt/beta-catenin signaling | |
| P478 | volume | 108 |
| Q35862843 | A functional connectome: regulation of Wnt/TCF-dependent transcription by pairs of pathway activators. |
| Q38950983 | Aberrant expression of CDK8 regulates the malignant phenotype and associated with poor prognosis in human laryngeal squamous cell carcinoma |
| Q35542572 | Activating the Wnt/β-Catenin Pathway for the Treatment of Melanoma--Application of LY2090314, a Novel Selective Inhibitor of Glycogen Synthase Kinase-3 |
| Q38521011 | Advances in targeted therapies for hepatocellular carcinoma in the genomic era. |
| Q35762264 | Apc Restoration Promotes Cellular Differentiation and Reestablishes Crypt Homeostasis in Colorectal Cancer |
| Q34669618 | Biology of colorectal cancer |
| Q35459134 | Boosting Wnt activity during colorectal cancer progression through selective hypermethylation of Wnt signaling antagonists |
| Q98945202 | Cellular and molecular architecture of the intestinal stem cell niche |
| Q37398834 | Citrobacter Infection and Wnt signaling |
| Q41140196 | Comprehensive Modeling and Discovery of Mebendazole as a Novel TRAF2- and NCK-interacting Kinase Inhibitor |
| Q38409303 | Consumption of Red/Processed Meat and Colorectal Carcinoma: Possible Mechanisms Underlying the Significant Association |
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| Q37231321 | Direct Pharmacological Inhibition of β-Catenin by RNA Interference in Tumors of Diverse Origin |
| Q24337325 | Disruption of Wnt/β-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells |
| Q35032477 | Down-regulation of miR-129-5p inhibits growth and induces apoptosis in laryngeal squamous cell carcinoma by targeting APC. |
| Q38012254 | Drugging Wnt signalling in cancer |
| Q37966605 | Dysregulation of Wnt/β-catenin signaling in gastrointestinal cancers |
| Q39148126 | Expression and localization of axin 2 in colorectal carcinoma and its clinical implication. |
| Q41870215 | Genetic ablation of β-catenin inhibits the proliferative phenotype of mouse liver adenomas |
| Q35214688 | HSP105 recruits protein phosphatase 2A to dephosphorylate β-catenin. |
| Q36075534 | In vivo and in vitro models for the therapeutic targeting of Wnt signaling using a Tet-OΔN89β-catenin system |
| Q37068621 | Inactivating mutations of RNF43 confer Wnt dependency in pancreatic ductal adenocarcinoma |
| Q33709769 | Itraconazole exerts its anti-melanoma effect by suppressing Hedgehog, Wnt, and PI3K/mTOR signaling pathways |
| Q39034769 | LEF1 and B9L shield β-catenin from inactivation by Axin, desensitizing colorectal cancer cells to tankyrase inhibitors |
| Q34130203 | LRP5 polymorphism-A potential predictor of the clinical outcome in advanced gastric cancer patients treated with EOF regimen |
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| Q37731426 | MicroRNA-224 suppresses colorectal cancer cell migration by targeting Cdc42. |
| Q42206266 | Novel β-carbolines against colorectal cancer cell growth via inhibition of Wnt/β-catenin signaling. |
| Q37438495 | Oncogenic mutations in adenomatous polyposis coli (Apc) activate mechanistic target of rapamycin complex 1 (mTORC1) in mice and zebrafish |
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| Q63664483 | PanglaoDB: a web server for exploration of mouse and human single-cell RNA sequencing data |
| Q38674444 | Pharmacokinetics and biodistribution of recently-developed siRNA nanomedicines |
| Q38752182 | RBM5-AS1 Is Critical for Self-Renewal of Colon Cancer Stem-like Cells. |
| Q38876701 | Reproducibility of parameter learning with missing observations in naive Wnt Bayesian network trained on colorectal cancer samples and doxycycline-treated cell lines. |
| Q38023902 | Sclerostin: a possible target for the management of cancer-induced bone disease |
| Q35869295 | Small-molecule inhibitors of Wnt signaling pathway: towards novel anticancer therapeutics |
| Q101574338 | Synthetic lethality between MyD88 loss and mutations in Wnt/β-catenin pathway in intestinal tumor epithelial cells |
| Q37622949 | Targeting MUC1-C inhibits the AKT-S6K1-elF4A pathway regulating TIGAR translation in colorectal cancer |
| Q46107456 | Targeting PTPRK-RSPO3 colon tumours promotes differentiation and loss of stem-cell function. |
| Q39216658 | Targeting Tankyrase to Fight WNT-dependent Tumours |
| Q37721815 | The Influence of Spirulina platensis Filtrates on Caco-2 Proliferative Activity and Expression of Apoptosis-Related microRNAs and mRNA. |
| Q37066468 | The Poly(ADP-ribose) Polymerase Enzyme Tankyrase Antagonizes Activity of the β-Catenin Destruction Complex through ADP-ribosylation of Axin and APC2 |
| Q27009129 | The osteocyte as a therapeutic target in the treatment of osteoporosis |
| Q41441154 | Treg-cell depletion promotes chemokine production and accumulation of CXCR3(+) conventional T cells in intestinal tumors. |
| Q37305230 | Wnt secretion is required to maintain high levels of Wnt activity in colon cancer cells |
| Q38374930 | Wnt/β-catenin signaling pathway may regulate the expression of angiogenic growth factors in hepatocellular carcinoma |
| Q37233140 | miR-582-5P induces colorectal cancer cell proliferation by targeting adenomatous polyposis coli. |
| Q49547317 | β-Catenin mRNA Silencing and MEK Inhibition Display Synergistic Efficacy in Preclinical Tumor Models |
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