| scholarly article | Q13442814 |
| P50 | author | Albert J.R. Heck | Q2865808 |
| Hans Clevers | Q1579050 | ||
| Shabaz Mohammed | Q41889840 | ||
| Tokameh Mahmoudi | Q87972298 | ||
| P2093 | author name string | Vivian S W Li | |
| Robert G J Vries | |||
| Ser Sue Ng | |||
| Nadia Taouatas | |||
| P2860 | cites work | TNIK, a novel member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and regulates the cytoskeleton | Q22010654 |
| Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signalling | Q24290355 | ||
| Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex | Q24294443 | ||
| The Traf2- and Nck-interacting kinase as a putative effector of Rap2 to regulate actin cytoskeleton | Q24302294 | ||
| Identification of c-MYC as a target of the APC pathway | Q24310637 | ||
| Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly | Q24312910 | ||
| The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells | Q24314491 | ||
| Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma | Q24336272 | ||
| Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC | Q24336321 | ||
| The chromatin remodelling factor Brg-1 interacts with beta-catenin to promote target gene activation | Q24534469 | ||
| Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels | Q27860531 | ||
| Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells | Q27860717 | ||
| Wnt/beta-catenin signaling in development and disease | Q27860784 | ||
| Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification | Q28131753 | ||
| Functional interaction of beta-catenin with the transcription factor LEF-1 | Q28286884 | ||
| Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4 | Q28592260 | ||
| XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos | Q28619032 | ||
| The transcriptional coactivator CBP interacts with beta-catenin to activate gene expression | Q28640562 | ||
| Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway | Q28640887 | ||
| Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors | Q28640916 | ||
| Linking colorectal cancer to Wnt signaling | Q29619810 | ||
| Synergy between tumor suppressor APC and the beta-catenin-Tcf4 target Tcf1. | Q33874338 | ||
| Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/beta -catenin signaling is activated in human colon tumors | Q33952813 | ||
| The p300/CBP acetyltransferases function as transcriptional coactivators of beta-catenin in vertebrates | Q34486253 | ||
| Beta-catenin hits chromatin: regulation of Wnt target gene activation | Q34967116 | ||
| Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells | Q36540321 | ||
| Highly robust, automated, and sensitive online TiO2-based phosphoproteomics applied to study endogenous phosphorylation in Drosophila melanogaster. | Q40045831 | ||
| The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes | Q40309718 | ||
| Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector | Q40773079 | ||
| Differential localization by in situ hybridization of distinct keratin mRNA species during intestinal epithelial cell development and differentiation | Q48118806 | ||
| The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification 1 | Q107343694 | ||
| P433 | issue | 21 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | TRAF2 and NCK interacting kinase | Q21108517 |
| P304 | page(s) | 3329-40 | |
| P577 | publication date | 2009-11-04 | |
| P1433 | published in | The EMBO Journal | Q1278554 |
| P1476 | title | The kinase TNIK is an essential activator of Wnt target genes | |
| P478 | volume | 28 |
| Q53362870 | A Role for MYC in Lithium-Stimulated Repair of the Colonic Epithelium After DSS-Induced Damage in Mice. |
| Q90356350 | A homozygous missense variant in CACNB4 encoding the auxiliary calcium channel beta4 subunit causes a severe neurodevelopmental disorder and impairs channel and non-channel functions |
| Q35357838 | A novel aminothiazole KY-05009 with potential to inhibit Traf2- and Nck-interacting kinase (TNIK) attenuates TGF-β1-mediated epithelial-to-mesenchymal transition in human lung adenocarcinoma A549 cells |
| Q39828938 | A null mutation in TNIK defines a novel locus for intellectual disability |
| Q34685322 | Acetylation of human TCF4 (TCF7L2) proteins attenuates inhibition by the HBP1 repressor and induces a conformational change in the TCF4::DNA complex |
| Q27323158 | Agonistic and antagonistic roles for TNIK and MINK in non-canonical and canonical Wnt signalling |
| Q35698863 | CD27 signaling on chronic myelogenous leukemia stem cells activates Wnt target genes and promotes disease progression |
| Q42323497 | CD70/CD27 signaling promotes blast stemness and is a viable therapeutic target in acute myeloid leukemia |
| Q35591995 | Can we safely target the WNT pathway? |
| Q42378297 | Canonical and non-canonical WNT signaling in cancer stem cells and their niches: Cellular heterogeneity, omics reprogramming, targeted therapy and tumor plasticity (Review) |
| Q27022532 | Cell-context dependent TCF/LEF expression and function: alternative tales of repression, de-repression and activation potentials |
| Q64072034 | Characterization of the ERG-regulated Kinome in Prostate Cancer Identifies TNIK as a Potential Therapeutic Target |
| Q28258350 | Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes |
| Q41140196 | Comprehensive Modeling and Discovery of Mebendazole as a Novel TRAF2- and NCK-interacting Kinase Inhibitor |
| Q37998459 | DISC1 Pathway in Brain Development: Exploring Therapeutic Targets for Major Psychiatric Disorders |
| Q28250914 | DISC1 at 10: connecting psychiatric genetics and neuroscience |
| Q39085740 | Determinants of metastatic competency in colorectal cancer |
| Q83225935 | Developmentally regulated splice variants mediate transcriptional repressor functions during eye formation |
| Q41918771 | Downregulation of the Wnt/β-catenin signaling pathway by Cacnb4. |
| Q37840943 | Drug discovery approaches to target Wnt signaling in cancer stem cells |
| Q46132376 | Dynamic change of TNIK in response to tumor necrosis factor alpha in a TRAF2-dependent manner |
| Q40048751 | ERAP1 and PDE8A Are Downregulated in Cattle Protected against Bovine Tuberculosis |
| Q33738834 | Emergence of TNIK inhibitors in cancer therapeutics |
| Q39516790 | Enormous influence of TNIK knockdown on intracellular signals and cell survival |
| Q52675080 | Five novel loci associated with antipsychotic treatment response in patients with schizophrenia: a genome-wide association study. |
| Q47215094 | Functions of the APC tumor suppressor protein dependent and independent of canonical WNT signaling: implications for therapeutic targeting |
| Q37381860 | Gene Expression Architecture of Mouse Dorsal and Tail Skin Reveals Functional Differences in Inflammation and Cancer. |
| Q34413899 | Genetic variation in hippocampal microRNA expression differences in C57BL/6 J X DBA/2 J (BXD) recombinant inbred mouse strains |
| Q40277663 | Genome-wide association study identifies novel susceptible loci and highlights Wnt/beta-catenin pathway in the development of adolescent idiopathic scoliosis |
| Q47156532 | Genomic and transcriptomic heterogeneity in metaplastic carcinomas of the breast |
| Q37882048 | How do they do Wnt they do?: regulation of transcription by the Wnt/β-catenin pathway. |
| Q40234126 | Identification of Phosphorylation Consensus Sequences and Endogenous Neuronal Substrates of the Psychiatric Risk Kinase TNIK. |
| Q28591962 | Identification of mechanosensitive genes during skeletal development: alteration of genes associated with cytoskeletal rearrangement and cell signalling pathways |
| Q102075548 | Improving target assessment in biomedical research: the GOT-IT recommendations |
| Q30386219 | Induction of Macrophage Function in Human THP-1 Cells Is Associated with Rewiring of MAPK Signaling and Activation of MAP3K7 (TAK1) Protein Kinase |
| Q39744343 | MAP3K1 functionally interacts with Axin1 in the canonical Wnt signalling pathway. |
| Q28578746 | MINK and TNIK differentially act on Rap2-mediated signal transduction to regulate neuronal structure and AMPA receptor function |
| Q34202840 | MicroRNA roles in beta-catenin pathway |
| Q34292029 | Misshapen-like kinase 1 (MINK1) is a novel component of striatin-interacting phosphatase and kinase (STRIPAK) and is required for the completion of cytokinesis |
| Q37812683 | New avenues to target Wnt/β-catenin signaling |
| Q28116474 | Nuclear factor of activated T cells (NFAT) proteins repress canonical Wnt signaling via its interaction with Dishevelled (Dvl) protein and participate in regulating neural progenitor cell proliferation and differentiation |
| Q41881027 | Organization of TNIK in dendritic spines |
| Q103002435 | Pharmacological blockage of transforming growth factor-β signalling by a Traf2- and Nck-interacting kinase inhibitor, NCB-0846 |
| Q35820715 | Prognostic significance of Traf2- and Nck- interacting kinase (TNIK) in colorectal cancer |
| Q39166565 | Proteome profiling of exosomes derived from human primary and metastatic colorectal cancer cells reveal differential expression of key metastatic factors and signal transduction components |
| Q39507533 | Quantitative phosphoproteomics of transforming growth factor-β signaling in colon cancer cells. |
| Q56530863 | Rap2 and TNIK control Plexin-dependent tiled synaptic innervation in |
| Q38193259 | Regulation of Wnt/β-catenin signaling by posttranslational modifications |
| Q36786350 | Satb1 regulates the self-renewal of hematopoietic stem cells by promoting quiescence and repressing differentiation commitment. |
| Q36132584 | Screening of reproduction-related single-nucleotide variations from MeDIP-seq data in sheep |
| Q24307319 | Smad inhibition by the Ste20 kinase Misshapen |
| Q41092608 | Synergistic inhibition effect of TNIK inhibitor KY-05009 and receptor tyrosine kinase inhibitor dovitinib on IL-6-induced proliferation and Wnt signaling pathway in human multiple myeloma cells |
| Q26742019 | TCF/LEF Transcription Factors: An Update from the Internet Resources |
| Q38048246 | TCF/LEFs and Wnt signaling in the nucleus. |
| Q37223261 | TNIK inhibition abrogates colorectal cancer stemness |
| Q38384937 | TNIK serves as a novel biomarker associated with poor prognosis in patients with pancreatic cancer |
| Q91522152 | TNIK signaling imprints CD8+ T cell memory formation early after priming |
| Q37690413 | TNiK is required for postsynaptic and nuclear signaling pathways and cognitive function |
| Q36506697 | Targeting Wnt pathways in disease |
| Q38600094 | Targeting the Wnt signaling pathway in colorectal cancer |
| Q42746774 | The deubiquitinase USP28 controls intestinal homeostasis and promotes colorectal cancer |
| Q52782861 | The emergence of TNIK as a therapeutic target for colorectal cancer. |
| Q42177839 | The essential role of TNIK gene amplification in gastric cancer growth |
| Q34384112 | The germinal center kinase TNIK is required for canonical NF-κB and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor |
| Q28487781 | The inverse F-BAR domain protein srGAP2 acts through srGAP3 to modulate neuronal differentiation and neurite outgrowth of mouse neuroblastoma cells |
| Q28476157 | The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/β-catenin coactivators essential for intestinal homeostasis |
| Q26865781 | The many faces and functions of β-catenin |
| Q37713641 | The myc 3' wnt-responsive element suppresses colonic tumorigenesis |
| Q37940376 | The proteomics of cancer stem cells: potential clinical applications for innovative research in oncology |
| Q35223834 | The psychiatric disease risk factors DISC1 and TNIK interact to regulate synapse composition and function. |
| Q93159737 | The transcriptional coactivator WBP2 primes triple-negative breast cancer cells for responses to Wnt signaling via the JNK/Jun kinase pathway |
| Q38749841 | Therapeutic targeting of CD70 and CD27. |
| Q26778983 | Therapeutic targets in the Wnt signaling pathway: Feasibility of targeting TNIK in colorectal cancer |
| Q53142724 | Traf2- and Nck-interacting kinase (TNIK) is involved in the anti-cancer mechanism of dovitinib in human multiple myeloma IM-9 cells. |
| Q34074375 | Traf2- and Nck-interacting kinase is essential for canonical Wnt signaling in Xenopus axis formation |
| Q34089949 | Whole genome expression profiling shows that BRG1 transcriptionally regulates UV inducible genes and other novel targets in human cells |
| Q54249872 | Wnt Signalling in Gastrointestinal Epithelial Stem Cells. |
| Q24337717 | Wnt signaling through inhibition of β-catenin degradation in an intact Axin1 complex |
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