XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos (scientific article)

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Q34471536	Epsin is required for Dishevelled stability and Wnt signalling activation in colon cancer development
Q24290593	Essential tyrosine residues for interaction of the non-receptor protein-tyrosine phosphatase PTP1B with N-cadherin
Q24683274	Establishment of the dorsal-ventral axis in Xenopus embryos coincides with the dorsal enrichment of dishevelled that is dependent on cortical rotation
Q24683939	Establishment of the dorso-ventral axis in Xenopus embryos is presaged by early asymmetries in beta-catenin that are modulated by the Wnt signaling pathway
Q44199605	Evidence that Armadillo transduces wingless by mediating nuclear export or cytosolic activation of Pangolin
Q34087711	Evidence that fold-change, and not absolute level, of beta-catenin dictates Wnt signaling
Q90622919	Evolution and Regulation of Limb Regeneration in Arthropods
Q33377041	Evolutionarily conserved transcriptional co-expression guiding embryonic stem cell differentiation
Q33891005	Excess beta-catenin promotes accumulation of transcriptionally active p53.
Q33767790	Exogenous activation of Wnt/β-catenin signaling attenuates binge alcohol-induced deficient bone fracture healing
Q49427525	Exon 3 mutations of CTNNB1 drive tumorigenesis: a review
Q36902840	Expanding mTOR signaling
Q39255803	Exploiting the WNT Signaling Pathway for Clinical Purposes
Q28505373	Expression of CD44 in Apc and Tcf mutant mice implies regulation by the WNT pathway
Q36310657	Expression of Cyclin D1 Is Associated with β-Catenin Expression and Correlates with Good Prognosis in Colorectal Adenocarcinoma
Q42451952	Expression of Nemo-like kinase after spinal cord injury in rats
Q24302207	Expression of Wnt and Notch pathway genes in a pluripotent human embryonal carcinoma cell line and embryonic stem cell
Q48581302	Expression of beta-catenin and the adenomatous polyposis coli tumour suppressor protein in mouse neocortical cells in vitro
Q42442379	Expression of beta-catenin in basal cell carcinoma
Q74107411	Expression patterns of Wnt genes in mouse gut development
Q35084907	Expression profiles and functional analyses of Wnt-related genes in human joint disorders
Q38678857	Extracellular inhibitors can attenuate tumorigenic Wnt pathway activity in adenomatous polyposis coli mutants: Predictions of a validated mathematical model
Q38289851	Eya1 and Six1 promote neurogenesis in the cranial placodes in a SoxB1-dependent fashion
Q51887075	FGF/MAPK/Ets signaling renders pigment cell precursors competent to respond to Wnt signal by directly controlling Ci-Tcf transcription.
Q28505123	FGF4, a direct target of LEF1 and Wnt signaling, can rescue the arrest of tooth organogenesis in Lef1(-/-) mice
Q38194508	Factors affecting the nuclear localization of β-catenin in normal and malignant tissue
Q42237482	Fezf2 promotes neuronal differentiation through localised activation of Wnt/β-catenin signalling during forebrain development
Q36672652	Flying at the head of the pack: Wnt biology in Drosophila.
Q39866344	Follow-up: Prospective compound design using the 'SAR Matrix' method and matrix-derived conditional probabilities of activity
Q28218994	Formation of multiple hearts in mice following deletion of beta-catenin in the embryonic endoderm
Q58450866	Foxl1-deficient mice exhibit aberrant epithelial cell positioning resulting from dysregulated EphB/EphrinB expression in the small intestine
Q44081282	Fractal and image analysis of the microvasculature in normal intestinal submucosa and intestinal polyps in Apc(Min/+) mice
Q28585212	Frat is dispensable for canonical Wnt signaling in mammals
Q55019423	Frequent beta-catenin abnormalities in bone and soft-tissue tumors.
Q77486338	Frizzled receptors activate a novel JNK-dependent pathway that may lead to apoptosis
Q36807773	Frizzled receptors signal through G proteins
Q28119021	Frizzled-9 is activated by Wnt-2 and functions in Wnt/beta -catenin signaling
Q39175438	Fucoidan inhibited 4T1 mouse breast cancer cell growth in vivo and in vitro via downregulation of Wnt/β-catenin signaling
Q35978882	Function of Wnt/β-catenin in counteracting Tcf3 repression through the Tcf3-β-catenin interaction
Q52182998	Function of zebrafish beta-catenin and TCF-3 in dorsoventral patterning.
Q36709977	Functional analysis of DNA bending and unwinding by the high mobility group domain of LEF-1.
Q24309053	Functional analysis of Sox10 mutations found in human Waardenburg-Hirschsprung patients
Q40949117	Functional characterization of multiple transactivating elements in beta-catenin, some of which interact with the TATA-binding protein in vitro
Q28511342	Functional domains of axin. Importance of the C terminus as an oligomerization domain
Q24309150	GBP, an inhibitor of GSK-3, is implicated in Xenopus development and oncogenesis
Q34809015	GRG5/AES interacts with T-cell factor 4 (TCF4) and downregulates Wnt signaling in human cells and zebrafish embryos
Q22253256	GSK-3beta-dependent phosphorylation of adenomatous polyposis coli gene product can be modulated by beta-catenin and protein phosphatase 2A complexed with Axin
Q37242485	Gastrin is a target of the beta-catenin/TCF-4 growth-signaling pathway in a model of intestinal polyposis
Q37158051	Genetic causes of microcephaly and lessons for neuronal development
Q28509512	Genetic evidence that SOST inhibits WNT signaling in the limb
Q33939068	Genotype to phenotype: analyzing the effects of inherited mutations in colorectal cancer families
Q40515236	Germinated brown rice (GBR) reduces the incidence of aberrant crypt foci with the involvement of beta-catenin and COX-2 in azoxymethane-induced colon cancer in rats
Q42265763	Ginsenoside-Rb1 targets chemotherapy-resistant ovarian cancer stem cells via simultaneous inhibition of Wnt/β-catenin signaling and epithelial-to-mesenchymal transition
Q54536901	Ginsenoside-Rg1 induces vascular endothelial growth factor expression through the glucocorticoid receptor-related phosphatidylinositol 3-kinase/Akt and beta-catenin/T-cell factor-dependent pathway in human endothelial cells.
Q33528931	Global regulator SATB1 recruits beta-catenin and regulates T(H)2 differentiation in Wnt-dependent manner.
Q40627232	Glucocorticoids Control β-Catenin Protein Expression and Localization through Distinct Pathways that Can Be Uncoupled by Disruption of Signaling Events Required for Tight Junction Formation in Rat Mammary Epithelial Tumor Cells
Q52051139	Groucho corepressor proteins regulate otic vesicle outgrowth.
Q37486782	Guanylyl cyclase C in colorectal cancer: susceptibility gene and potential therapeutic target
Q41588808	Gut reaction to Wnt signaling in worms
Q40930487	H-Ras activation promotes cytoplasmic accumulation and phosphoinositide 3-OH kinase association of beta-catenin in epidermal keratinocytes.
Q38318721	HIC-5 is a novel repressor of lymphoid enhancer factor/T-cell factor-driven transcription
Q35214688	HSP105 recruits protein phosphatase 2A to dephosphorylate β-catenin.
Q90754736	Habenular TCF7L2 links nicotine addiction to diabetes
Q36428132	Hamartin and tuberin modulate gene transcription via beta-catenin
Q34366233	Heads or tails: Wnts and anterior-posterior patterning
Q40974831	Heart induction by Wnt antagonists depends on the homeodomain transcription factor Hex.
Q58553009	Hepatitis B virus promotes β-catenin-signalling and disassembly of adherens junctions in a Src kinase dependent fashion
Q24546094	High expression of the HMG box factor sox-13 in arterial walls during embryonic development
Q47139136	High-Temperature Requirement A1 (Htra1) - A Novel Regulator of Canonical Wnt Signaling
Q33884901	Hippocampus formation: an intriguing collaboration.
Q37457650	Homeobox protein VentX induces p53-independent apoptosis in cancer cells
Q44376501	Hot spots in Tcf4 for the interaction with beta-catenin
Q37882048	How do they do Wnt they do?: regulation of transcription by the Wnt/β-catenin pathway.
Q42445322	Human telomerase reverse transcriptase (hTERT) is a target gene of β-catenin in human colorectal tumors
Q40210594	Hyaluronan-CD44 interaction with neural Wiskott-Aldrich syndrome protein (N-WASP) promotes actin polymerization and ErbB2 activation leading to beta-catenin nuclear translocation, transcriptional up-regulation, and cell migration in ovarian tumor ce
Q38702955	Hyper activation of β-catenin signalling induced by IKKε inhibition thwarts colorectal cancer cell proliferation
Q34465977	Hypomethylation-associated up-regulation of TCF3 expression and recurrence in stage II and III colorectal cancer
Q92670011	Hypothesis: Retinoblastoma protein inactivation mediates effects of histone deacetylase inhibitor-induced Wnt hyperactivation in colorectal cancer cells
Q24305168	I-mfa domain proteins interact with Axin and affect its regulation of the Wnt and c-Jun N-terminal kinase signaling pathways
Q53389043	ITF-2, a downstream target of the Wnt/TCF pathway, is activated in human cancers with beta-catenin defects and promotes neoplastic transformation.
Q34268517	Identification Of Small Molecule TRABID Deubiquitinase Inhibitors By Computation-Based Virtual Screen.
Q24320344	Identification and localization of a neurally expressed member of the plakoglobin/armadillo multigene family
Q30430577	Identification and mechanism of regulation of the zebrafish dorsal determinant
Q22008756	Identification of APC2, a homologue of the adenomatous polyposis coli tumour suppressor
Q35959929	Identification of E-cadherin signature motifs functioning as cleavage sites for Helicobacter pylori HtrA
Q35002366	Identification of Mom12 and Mom13, two novel modifier loci of Apc (Min) -mediated intestinal tumorigenesis
Q42831096	Identification of Tcf-4 as a transcriptional target of p53 signalling
Q24793754	Identification of Wnt responsive genes using a murine mammary epithelial cell line model system
Q28295415	Identification of a domain of Axin that binds to the serine/threonine protein phosphatase 2A and a self-binding domain
Q39457422	Identification of a mouse homolog of the human BTEB2 transcription factor as a beta-catenin-independent Wnt-1-responsive gene
Q24317602	Identification of a new human catenin gene family member (ARVCF) from the region deleted in velo-cardio-facial syndrome
Q44577868	Identification of a phylogenetically conserved activin-responsive enhancer in the Zic3 gene
Q28215785	Identification of a promoter-specific transcriptional activation domain at the C terminus of the Wnt effector protein T-cell factor 4
Q40595314	Identification of a role for beta-catenin in the establishment of a bipolar mitotic spindle
Q28363408	Identification of an invasive, N-cadherin-expressing epithelial cell type in endometriosis using a new cell culture model
Q73711511	Identification of essential sequence motifs in the node/notochord enhancer of Foxa2 (Hnf3beta) gene that are conserved across vertebrate species
Q44249209	Identification of four distinct pools of catenins in mammalian cells and transformation-dependent changes in catenin distributions among these pools
Q24294539	Identification of novel NPRAP/δ-catenin-interacting proteins and the direct association of NPRAP with dynamin 2
Q36356732	Identification of the 187 bp EphA7 Genomic DNA as the Dorsal Midline-Specific Enhancer of the Diencephalon and Mesencephalon
Q61804534	Identification of the X-linked germ cell specific miRNAs (XmiRs) and their functions
Q39030240	Identification of two Wnt-responsive elements in the intron of RING finger protein 43 (RNF43) gene
Q38305472	Identification of two regulatory elements within the high mobility group box transcription factor XTCF-4.
Q24568035	Illegitimate WNT signaling promotes proliferation of multiple myeloma cells
Q36765956	Immune Modulation of the T Cell Response in Asthma through Wnt10b
Q42521003	Immunohistochemical comparison of beta-catenin expression by human normal epidermis and epidermal tumors
Q52979434	Immunohistological analysis of E-cadherin, alpha-, beta- and gamma-catenin expression in colorectal cancer: implications for cell adhesion and signaling.
Q36294220	Impaired mammary gland and lymphoid development caused by inducible expression of Axin in transgenic mice
Q35741631	Impaired neural development caused by inducible expression of Axin in transgenic mice
Q37873905	Implication of Wnt signaling in neuronal polarization.
Q34142593	Inactivation of germline mutant APC alleles by attenuated somatic mutations: a molecular genetic mechanism for attenuated familial adenomatous polyposis
Q44897188	Induction of HDAC2 expression upon loss of APC in colorectal tumorigenesis
Q42404046	Inhibition by chondroitin sulfate E can specify functional Wnt/β-catenin signaling thresholds in NIH3T3 fibroblasts
Q37691085	Inhibition of CCAR1, a Coactivator of β-Catenin, Suppresses the Proliferation and Migration of Gastric Cancer Cells
Q33419081	Inhibition of GSK3 phosphorylation of beta-catenin via phosphorylated PPPSPXS motifs of Wnt coreceptor LRP6.
Q24602885	Inhibition of Wnt signaling by ICAT, a novel beta-catenin-interacting protein
Q39003793	Inhibition of Wnt/β-catenin pathway by niclosamide: a therapeutic target for ovarian cancer.
Q33582157	Inhibition of beta-catenin-mediated transactivation by cadherin derivatives
Q38256000	Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation.
Q34481563	Inhibition of suppressive T cell factor 1 (TCF-1) isoforms in naive CD4+ T cells is mediated by IL-4/STAT6 signaling
Q24290612	Inhibition of the Wnt signaling pathway by Idax, a novel Dvl-binding protein
Q24298606	Inhibitory Gli3 activity negatively regulates Wnt/beta-catenin signaling
Q50949314	Inhibitory effect of a standardized pomegranate fruit extract on Wnt signalling in 1, 2-dimethylhydrazine induced rat colon carcinogenesis.
Q91008760	Initial characterization of Wnt-Tcf functions during Ciona heart development
Q40114861	Inositol pentakisphosphate mediates Wnt/beta-catenin signaling
Q36732647	Integrated morphogen signal inputs in gammadelta versus alphabeta T-cell differentiation.
Q24301688	Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal
Q28640539	Interaction among GSK-3, GBP, axin, and APC in Xenopus axis specification
Q28509243	Interaction of dishevelled and Xenopus axin-related protein is required for wnt signal transduction
Q24522854	Interaction of glycogen synthase kinase 3beta with the DF3/MUC1 carcinoma-associated antigen and beta-catenin
Q27929965	Interaction of yeast repressor-activator protein Ume6p with glycogen synthase kinase 3 homolog Rim11p
Q33652780	Intercellular Coupling of the Cell Cycle and Circadian Clock in Adult Stem Cell Culture
Q41612546	Interendothelial junctions: structure, signalling and functional roles.
Q37809668	International Union of Basic and Clinical Pharmacology. LXXX. The Class Frizzled Receptors
Q37698281	Interplay of cadherin-mediated cell adhesion and canonical Wnt signaling
Q33421205	Intramucosal distribution of WNT signaling components in human esophagus
Q38843283	Introducing STRaNDs: shuttling transcriptional regulators that are non-DNA binding
Q41894538	Involvement of Wnt signaling pathways in the metamorphosis of the bryozoan Bugula neritina
Q39706536	Involvement of the PI3K/Akt signaling pathway in platelet-derived growth factor-induced migration of human lens epithelial cells
Q30782016	Isolation and characterization of XKaiso, a transcriptional repressor that associates with the catenin Xp120(ctn) in Xenopus laevis
Q36885199	Isolation and characterization of chicken beta-catenin
Q22009424	Isolation of a mammalian homologue of a fission yeast differentiation regulator
Q34737997	Isoquercitrin suppresses colon cancer cell growth in vitro by targeting the Wnt/β-catenin signaling pathway
Q35953126	JmjC Domain-containing Protein 6 (Jmjd6) Derepresses the Transcriptional Repressor Transcription Factor 7-like 1 (Tcf7l1) and Is Required for Body Axis Patterning during Xenopus Embryogenesis
Q33558845	KLF4 interacts with beta-catenin/TCF4 and blocks p300/CBP recruitment by beta-catenin
Q24321278	Kaiso is a bimodal modulator for Wnt/beta-catenin signaling
Q33710603	Keeping a close eye on Wnt-1/wg signaling in Xenopus
Q42261458	Knockdown of SIRT7 enhances the osteogenic differentiation of human bone marrow mesenchymal stem cells partly via activation of the Wnt/β-catenin signaling pathway.
Q24290392	LDL-receptor-related proteins in Wnt signal transduction
Q52195693	LEF-1, a nuclear factor coordinating signaling inputs from wingless and decapentaplegic.
Q95721148	LEF1 turns over a new leaf
Q52697186	LINC00052 Promotes Gastric Cancer Cell Proliferation and Metastasis via Activating the Wnt/β-Catenin Signaling Pathway.
Q36995895	LRP5 and bone mass regulation: Where are we now?
Q35131658	LZTS2 is a novel beta-catenin-interacting protein and regulates the nuclear export of beta-catenin
Q49167258	Lef-1 and Tcf-3 transcription factors mediate tissue-specific Wnt signaling during Xenopus development
Q44512857	Lef/Tcf-dependent Wnt/beta-catenin signaling during Xenopus axis specification
Q28131788	Lessons from hereditary colorectal cancer
Q37122827	Leucine zipper tumor suppressor 2 inhibits cell proliferation and regulates Lef/Tcf-dependent transcription through Akt/GSK3β signaling pathway in lung cancer
Q37378529	Leucine-rich amelogenin peptide induces osteogenesis by activation of the Wnt pathway
Q28210565	Liganded androgen receptor interaction with beta-catenin: nuclear co-localization and modulation of transcriptional activity in neuronal cells
Q28215632	Linking beta-catenin to androgen-signaling pathway
Q29619810	Linking colorectal cancer to Wnt signaling
Q61796307	Loss of BCL9/9l suppresses Wnt driven tumourigenesis in models that recapitulate human cancer
Q38624956	Loss of Usp9x disrupts cell adhesion, and components of the Wnt and Notch signaling pathways in neural progenitors
Q38733090	Loss of the Wnt receptor frizzled 7 in the mouse gastric epithelium is deleterious and triggers rapid repopulation in vivo
Q52117042	Loss of the beta-catenin homologue aardvark causes ectopic stalk formation in Dictyostelium.
Q82253428	Luteolin inhibits cell proliferation during Azoxymethane-induced experimental colon carcinogenesis via Wnt/ β-catenin pathway
Q34068064	Lzts2 regulates embryonic cell movements and dorsoventral patterning through interaction with and export of nuclear β-catenin in zebrafish
Q24310282	MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling
Q28266828	MAGI-3 is involved in the regulation of the JNK signaling pathway as a scaffold protein for frizzled and Ltap
Q39744343	MAP3K1 functionally interacts with Axin1 in the canonical Wnt signalling pathway.
Q24635897	Maintaining embryonic stem cell pluripotency with Wnt signaling
Q29614622	Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
Q59072385	Mammalian MYC Proteins and Cancer
Q24305583	Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth
Q28586183	Master transcription factors determine cell-type-specific responses to TGF-β signaling
Q36842804	Maternal Dead-End1 is required for vegetal cortical microtubule assembly during Xenopus axis specification
Q38318137	Maternal XTcf1 and XTcf4 have distinct roles in regulating Wnt target genes
Q35568215	Maternal factors in zebrafish development
Q39571912	Matrix stiffening sensitizes epithelial cells to EGF and enables the loss of contact inhibition of proliferation
Q52337298	Mechanisms of Wnt signaling and control.
Q90345498	Mediator Condensates Localize Signaling Factors to Key Cell Identity Genes
Q52569557	Mediator is a transducer of Wnt/beta-catenin signaling.
Q44016906	Melanocyte-specific microphthalmia-associated transcription factor isoform activates its own gene promoter through physical interaction with lymphoid-enhancing factor 1.
Q40440952	Membrane depolarization induces the undulating phosphorylation/dephosphorylation of glycogen synthase kinase 3beta, and this dephosphorylation involves protein phosphatases 2A and 2B in SH-SY5Y human neuroblastoma cells
Q36917152	Membrane-anchored plakoglobins have multiple mechanisms of action in Wnt signaling
Q37109652	Methylation of DACT2 accelerates esophageal cancer development by activating Wnt signaling
Q58588269	MiR-30-5p suppresses cell chemoresistance and stemness in colorectal cancer through USP22/Wnt/β-catenin signaling axis
Q37090136	MicroRNA-199a is induced in dystrophic muscle and affects WNT signaling, cell proliferation, and myogenic differentiation
Q24536461	Microphthalmia-associated transcription factor interacts with LEF-1, a mediator of Wnt signaling
Q36670448	Mining the Wnt pathway for cancer therapeutics
Q36311384	Mitochondrial Dysfunction Due to Lack of Manganese Superoxide Dismutase Promotes Hepatocarcinogenesis
Q40096921	Mitogen-activated protein kinase p38 regulates the Wnt/cyclic GMP/Ca2+ non-canonical pathway.
Q37112722	Mitogen-activated protein kinases and Wnt/beta-catenin signaling: Molecular conversations among signaling pathways
Q35004421	Modeling the effect of APC truncation on destruction complex function in colorectal cancer cells
Q37609953	Modular Cre/lox system and genetic therapeutics for colorectal cancer
Q40585576	Modulation of beta-catenin phosphorylation/degradation by cyclin-dependent kinase 2.
Q33404575	Modulation of the beta-catenin signaling pathway by the dishevelled-associated protein Hipk1.
Q33775965	Modulation of transcriptional regulation by LEF-1 in response to Wnt-1 signaling and association with beta-catenin
Q36510498	Molecular bases of the regulation of bone remodeling by the canonical Wnt signaling pathway.
Q34680639	Molecular causes of colon cancer
Q24290958	Molecular cloning and characterization of MFRP, a novel gene encoding a membrane-type Frizzled-related protein
Q24535907	Molecular mechanisms of beta-catenin recognition by adenomatous polyposis coli revealed by the structure of an APC-beta-catenin complex
Q32052477	Molecular mechanisms that underlie structural and functional changes at the postsynaptic membrane during synaptic plasticity
Q38953543	Molecular pathways driving disease-specific alterations of intestinal epithelial cells
Q39387545	Molecular regulation and pharmacological targeting of the β-catenin destruction complex
Q38364430	Molecular signaling mechanisms of axon-glia communication in the peripheral nervous system
Q28553543	Monobenzyltin Complex C1 Induces Apoptosis in MCF-7 Breast Cancer Cells through the Intrinsic Signaling Pathway and through the Targeting of MCF-7-Derived Breast Cancer Stem Cells via the Wnt/β-Catenin Signaling Pathway
Q100633769	Multivalent tumor suppressor adenomatous polyposis coli promotes Axin biomolecular condensate formation and efficient β-catenin degradation
Q24534797	Murine Nr4a1 and Herpud1 are up-regulated by Wnt-1, but the homologous human genes are independent from beta-catenin activation
Q40520860	Murine Wnt-1 with an internal c-myc tag recombinantly produced in Escherichia coli can induce intracellular signaling of the canonical Wnt pathway in eukaryotic cells
Q54985905	Mutational analysis of beta-catenin gene in Japanese ovarian carcinomas: frequent mutations in endometrioid carcinomas.
Q100958900	Mutations and mechanisms of WNT pathway tumour suppressors in cancer
Q54994747	Mutations of the beta-catenin gene in endometrial carcinomas.
Q41191056	Myo-inositol reduces β-catenin activation in colitis
Q64076630	N-Terminal Domain Mediated Regulation of RORα1 Inhibits Invasive Growth in Prostate Cancer
Q33388624	NKCC1 (SLC12a2) induces a secondary axis in Xenopus laevis embryos independently of its co-transporter function.
Q36332725	Nanoparticulate TiO2 -mediated inhibition of the Wnt signaling pathway causes dendritic development disorder in cultured rat hippocampal neurons
Q34175008	Near-membrane ensemble elongation in the proline-rich LRP6 intracellular domain may explain the mysterious initiation of the Wnt signaling pathway
Q28640916	Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors
Q30657762	Negative regulation of axis formation and Wnt signaling in Xenopus embryos by the F-box/WD40 protein beta TrCP.
Q51910413	Nemo phosphorylates Even-skipped and promotes Eve-mediated repression of odd-skipped in even parasegments during Drosophila embryogenesis.
Q39446786	Neoplastic transformation of RK3E by mutant beta-catenin requires deregulation of Tcf/Lef transcription but not activation of c-myc expression
Q80033357	Neural induction in Xenopus requires inhibition of Wnt-beta-catenin signaling
Q42126114	Neural induction in the absence of mesoderm: beta-catenin-dependent expression of secreted BMP antagonists at the blastula stage in Xenopus.
Q41612519	Neural recognition molecules and synaptic plasticity
Q48189080	Neuronal localization of the Adenomatous polyposis coli tumor suppressor protein
Q54260437	New Wnt/β-catenin target genes promote experimental metastasis and migration of colorectal cancer cells through different signals.
Q34353150	New aspects of Wnt signaling pathways in higher vertebrates
Q37812683	New avenues to target Wnt/β-catenin signaling
Q28571541	Nexilin: a novel actin filament-binding protein localized at cell-matrix adherens junction
Q34758581	Non-canonical Wnt signaling in Xenopus: regulation of axis formation and gastrulation
Q33712458	Non-cell-autonomous stimulation of stem cell proliferation following ablation of Tcf3.
Q52136827	Notch signaling targets the Wingless responsiveness of a Ubx visceral mesoderm enhancer in Drosophila.
Q36075807	Nuclear and cytoplasmic localizations of the adenomatous polyposis coli protein.
Q73503222	Nuclear beta-catenin displays GSK-3beta- and APC-independent proteasome sensitivity in melanoma cells
Q34793950	Nuclear endpoint of Wnt signaling: neoplastic transformation induced by transactivating lymphoid-enhancing factor 1.
Q34662321	Nuclear factor-kappaB sensitizes to benzyl isothiocyanate-induced antiproliferation in p53-deficient colorectal cancer cells
Q35168502	Nuclear functions for plasma membrane-associated proteins?
Q39551576	Nuclear localization and formation of beta-catenin-lymphoid enhancer factor 1 complexes are not sufficient for activation of gene expression
Q74755575	Nuclear localization of beta-catenin in the hair matrix cells and differentiated keratinocytes
Q28645531	Nuclear localization signal-independent and importin/karyopherin-independent nuclear import of beta-catenin
Q52532636	Nuclear overexpression of the oncoprotein beta-catenin in colorectal cancer is localized predominantly at the invasion front.
Q24633420	Nuclear particles containing RNA polymerase III complexes associated with the junctional plaque protein plakophilin 2
Q52586994	Nuclear targeting of beta-catenin and p120ctn during thrombin-induced endothelial barrier dysfunction.
Q28509692	Nuclear-cytoplasmic shuttling of Axin regulates subcellular localization of beta-catenin
Q35165165	Nucleoporin 62-like protein activates canonical Wnt signaling through facilitating the nuclear import of β-catenin in zebrafish.
Q35129302	O2 regulates stem cells through Wnt/β-catenin signalling.
Q34764254	OSTM1 regulates beta-catenin/Lef1 interaction and is required for Wnt/beta-catenin signaling
Q34211306	Oct-3/4 regulates stem cell identity and cell fate decisions by modulating Wnt/β-catenin signalling
Q38986478	On the shoulders of Hubrecht: From embryos to stem cells
Q41352439	Oncoprotein networks
Q37015508	Opposing Wnt pathways orient cell polarity during organogenesis
Q35085761	Opposing effects of Tcf3 and Tcf1 control Wnt stimulation of embryonic stem cell self-renewal
Q33894555	Orphan nuclear receptor TLX activates Wnt/beta-catenin signalling to stimulate neural stem cell proliferation and self-renewal
Q35209119	Osa-containing Brahma chromatin remodeling complexes are required for the repression of wingless target genes
Q34767825	Overexpression of beta-catenin induces apoptosis independent of its transactivation function with LEF-1 or the involvement of major G1 cell cycle regulators
Q47895581	Overexpression of the thymosin beta-4 gene is associated with malignant progression of SW480 colon cancer cells
Q39828329	P-21-activated protein kinase-1 functions as a linker between insulin and Wnt signaling pathways in the intestine
Q51822082	P53 levels determine outcome during beta-catenin tumor initiation and metastasis in the mammary gland and male germ cells.
Q28204348	PAR-1 is a Dishevelled-associated kinase and a positive regulator of Wnt signalling
Q34886029	PAR1b promotes cell-cell adhesion and inhibits dishevelled-mediated transformation of Madin-Darby canine kidney cells
Q28511464	POU-V factors antagonize maternal VegT activity and beta-Catenin signaling in Xenopus embryos
Q28343682	PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs
Q92024428	PSPC1-interchanged interactions with PTK6 and β-catenin synergize oncogenic subcellular translocations and tumor progression
Q30444602	Par1b promotes hepatic-type lumen polarity in Madin Darby canine kidney cells via myosin II- and E-cadherin-dependent signaling
Q41590902	Paradigms to study signal transduction pathways in Drosophila.
Q36095701	Parallels between global transcriptional programs of polarizing Caco-2 intestinal epithelial cells in vitro and gene expression programs in normal colon and colon cancer
Q34962032	Past visits present: TCF/LEFs partner with ATFs for β-catenin-independent activity
Q34173672	Patterning and lineage specification in the amphibian embryo
Q34007852	Patterning the early sea urchin embryo
Q34870969	Pemphigus vulgaris identifies plakoglobin as key suppressor of c-Myc in the skin
Q34007479	Peroxisome proliferator-activated receptors in tumorigenesis: targets of tumour promotion and treatment
Q50036991	Pgam5 released from damaged mitochondria induces mitochondrial biogenesis via Wnt signaling
Q34327461	Pharmacological and genetic modulation of Wnt-targeted Cre-Lox-mediated gene expression in colorectal cancer cells
Q35096706	Phenotypes in mTERT⁺/⁻ and mTERT⁻/⁻ mice are due to short telomeres, not telomere-independent functions of telomerase reverse transcriptase
Q40725486	Phosphatidylinositol 3-kinase/Akt stimulates androgen pathway through GSK3beta inhibition and nuclear beta-catenin accumulation
Q34752073	Phosphorylation of TCF proteins by homeodomain-interacting protein kinase 2.
Q28609057	Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3beta regulates its stability
Q41883094	Physiological regulation of [beta]-catenin stability by Tcf3 and CK1epsilon
Q24291638	Pin1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APC
Q36674601	Pin1-mediated Modification Prolongs the Nuclear Retention of β-Catenin in Wnt3a-induced Osteoblast Differentiation.
Q24316226	Pitx2, a beta-catenin-regulated transcription factor, regulates the differentiation of outer root sheath cells cultured in vitro
Q47073294	Plakoglobin has both structural and signalling roles in zebrafish development
Q55346775	Plakoglobin restores tumor suppressor activity of p53R175H mutant by sequestering the oncogenic potential of β-catenin.
Q36328372	Plakoglobin suppresses epithelial proliferation and hair growth in vivo
Q28539201	Plakophilin-3 catenin associates with the ETV1/ER81 transcription factor to positively modulate gene activity
Q27305247	Plakophilin-3 is required for late embryonic amphibian development, exhibiting roles in ectodermal and neural tissues
Q36975748	Polycomb repressive complex PRC2 regulates Xenopus retina development downstream of Wnt/β-catenin signaling
Q22008488	Pontin52, an interaction partner of beta-catenin, binds to the TATA box binding protein
Q36124466	Powerful Drosophila screens that paved the wingless pathway.
Q90260476	Preclinical murine platform to evaluate therapeutic countermeasures against radiation-induced gastrointestinal syndrome
Q37003808	Presynaptic local signaling by a canonical wingless pathway regulates development of the Drosophila neuromuscular junction
Q42248345	Preventive inositol hexaphosphate extracted from rice bran inhibits colorectal cancer through involvement of Wnt/β-catenin and COX-2 pathways
Q52717980	Primary Cilia as a Signaling Platform for Control of Energy Metabolism.
Q36587738	Primary body axes of vertebrates: generation of a near-Cartesian coordinate system and the role of Spemann-type organizer
Q54442810	Prognostic significance of the wnt signalling pathway molecules APC, beta-catenin and E-cadherin in colorectal cancer: a tissue microarray-based analysis.
Q28302976	Promoter swapping between the genes for a novel zinc finger protein and beta-catenin in pleiomorphic adenomas with t(3;8)(p21;q12) translocations
Q40420990	Prostaglandin E2 Stimulates the beta-catenin/T cell factor-dependent transcription in colon cancer
Q40743689	Protection against anoikis and down-regulation of cadherin expression by a regulatable beta-catenin protein
Q57937244	Protein–protein interaction site mapping using NMR-detected mutational scanning
Q49170064	Proteolytic cleavage of beta-catenin by caspases: an in vitro analysis
Q44563875	Pygopus is required for embryonic brain patterning in Xenopus
Q49378541	RAPGEF5 Regulates Nuclear Translocation of β-Catenin.
Q38828509	RECK (reversion-inducing cysteine-rich protein with Kazal motifs) regulates migration, differentiation and Wnt/β-catenin signaling in human mesenchymal stem cells
Q40346466	RanBP3 enhances nuclear export of active (beta)-catenin independently of CRM1.
Q39760070	Rap1 stabilizes beta-catenin and enhances beta-catenin-dependent transcription and invasion in squamous cell carcinoma of the head and neck
Q34324645	Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation.
Q36045747	Reg4-induced mitogenesis involves Akt-GSK3β-β-Catenin-TCF-4 signaling in human colorectal cancer
Q40526020	Regulating the balance between peroxisome proliferator-activated receptor gamma and beta-catenin signaling during adipogenesis. A glycogen synthase kinase 3beta phosphorylation-defective mutant of beta-catenin inhibits expression of a subset of adip
Q28141939	Regulation of LEF-1/TCF transcription factors by Wnt and other signals
Q40867085	Regulation of Lef-mediated transcription and p53-dependent pathway by associating beta-catenin with CBP/p300.
Q37709217	Regulation of Lrp6 phosphorylation
Q58779722	Regulation of Osteoblast Metabolism by Wnt Signaling
Q34518987	Regulation of Sufu activity by p66β and Mycbp provides new insight into vertebrate Hedgehog signaling
Q37139384	Regulation of Tcf7l1 DNA binding and protein stability as principal mechanisms of Wnt/β-catenin signaling
Q28640468	Regulation of Wnt signaling by Sox proteins: XSox17 alpha/beta and XSox3 physically interact with beta-catenin
Q35215312	Regulation of Wnt/beta-catenin signaling by protein kinases
Q47072126	Regulation of armadillo by a Drosophila APC inhibits neuronal apoptosis during retinal development
Q28214709	Regulation of beta-catenin function by the IkappaB kinases
Q36275000	Regulation of beta-catenin levels and localization by overexpression of plakoglobin and inhibition of the ubiquitin-proteasome system
Q77582000	Regulation of chondrocyte differentiation and maturation
Q28581121	Regulation of dishevelled and beta-catenin in rat skeletal muscle: an alternative exercise-induced GSK-3beta signaling pathway
Q36698094	Regulation of germ layer formation by pluripotency factors during embryogenesis
Q47073176	Regulation of hhex expression in the yolk syncytial layer, the potential Nieuwkoop center homolog in zebrafish
Q38656134	Regulation of induced pluripotent stem (iPS) cell induction by Wnt/β-catenin signaling
Q34244360	Regulation of lineage commitment during lymphocyte development
Q24541401	Regulation of lymphoid enhancer factor 1/T-cell factor by mitogen-activated protein kinase-related Nemo-like kinase-dependent phosphorylation in Wnt/beta-catenin signaling
Q52016125	Regulation of prostate cell growth and morphogenesis by Dickkopf-3.
Q48147021	Regulation of the early expression patterns of the zebrafish Dishevelled-interacting proteins Dapper1 and Dapper2.
Q48906092	Relationship of vegetal cortical dorsal factors in the Xenopus egg with the Wnt/beta-catenin signaling pathway
Q46639710	Reorganization of actin cytoskeleton by FRIED, a Frizzled-8 associated protein tyrosine phosphatase
Q28586947	Repression of Nanog gene transcription by Tcf3 limits embryonic stem cell self-renewal
Q44017775	Repression through a distal TCF-3 binding site restricts Xenopus myf-5 expression in gastrula mesoderm
Q33601669	Repressor activity of Headless/Tcf3 is essential for vertebrate head formation.
Q40173785	Requirement for a Nuclear Function of β-Catenin in Wnt Signaling
Q37142420	Requirement for active glycogen synthase kinase-3β in TGF-β1 upregulation of connective tissue growth factor (CCN2/CTGF) levels in human gingival fibroblasts
Q28507627	Requirement for beta-catenin in anterior-posterior axis formation in mice
Q37197987	Requirement of Wnt/beta-catenin signaling in pronephric kidney development
Q37110412	Rescue of a Wnt mutation by an activated form of LEF-1: regulation of maintenance but not initiation of Brachyury expression
Q24681968	Restricted high level expression of Tcf-4 protein in intestinal and mammary gland epithelium
Q34761115	Retinoic acid-activated Ndrg1a represses Wnt/β-catenin signaling to allow Xenopus pancreas, oesophagus, stomach, and duodenum specification
Q35149000	Retracted: KCTD1 Suppresses Canonical Wnt Signaling Pathway by Enhancing β-catenin Degradation
Q33988164	Retracted: Silymarin Targets β-Catenin Signaling in Blocking Migration/Invasion of Human Melanoma Cells
Q39431964	Reversal of Xenopus Oct25 function by disruption of the POU domain structure
Q35010360	Revisions to the Xenopus gastrula fate map: implications for mesoderm induction and patterning
Q33959704	Rho family proteins in cell adhesion and cell migration.
Q37360933	Robust self-renewal of rat embryonic stem cells requires fine-tuning of glycogen synthase kinase-3 inhibition
Q64105061	Role of β-Catenin Activation Levels and Fluctuations in Controlling Cell Fate
Q34340040	Roles of cytoskeletal and junctional plaque proteins in nuclear signaling
Q34850710	Ror receptor tyrosine kinases: orphans no more
Q55412924	SOXF factors regulate murine satellite cell self-renewal and function through inhibition of β-catenin activity.
Q24319970	Secreted Frizzled-related protein-1 is a negative regulator of androgen receptor activity in prostate cancer
Q22011203	Secreted frizzled-related protein-1 binds directly to Wingless and is a biphasic modulator of Wnt signaling
Q38291853	Selection of multipotent stem cells during morphogenesis of small intestinal crypts of Lieberkuhn is perturbed by stimulation of Lef-1/beta-catenin signaling
Q24683255	Selective uncoupling of p120(ctn) from E-cadherin disrupts strong adhesion
Q52726088	Sending mixed signals: Cilia-dependent signaling during development and disease.
Q43897843	Sequencing of the rat beta-catenin gene (Ctnnb1) and mutational analysis of liver tumors induced by 2-amino-3-methylimidazo[4,5-f]quinoline
Q36715595	Siamois is required for formation of Spemann's organizer
Q24530639	Signal transduction by the Wnt family of ligands
Q36254931	Signaling and adhesion activities of mammalian beta-catenin and plakoglobin in Drosophila
Q45314408	Signaling by APC mutants
Q33652999	Signaling from the adherens junction.
Q26782820	Signaling in Fibrosis: TGF-β, WNT, and YAP/TAZ Converge
Q28834460	Signalling Through Retinoic Acid Receptors is Required for Reprogramming of Both Mouse Embryonic Fibroblast Cells and Epiblast Stem Cells to Induced Pluripotent Stem Cells
Q29619296	Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation
Q35837254	Slit2 as a β-catenin/Ctnnb1-dependent retrograde signal for presynaptic differentiation
Q34083378	Smad4-mediated signaling inhibits intestinal neoplasia by inhibiting expression of β-catenin.
Q36759505	Small molecule inhibitors of the Dishevelled-CXXC5 interaction are new drug candidates for bone anabolic osteoporosis therapy
Q31038919	Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex
Q34067016	Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas
Q36397987	Sox3 expression is maintained by FGF signaling and restricted to the neural plate by Vent proteins in the Xenopus embryo
Q40591608	Stabilized beta-catenin promotes hepatocyte proliferation and inhibits TNFalpha-induced apoptosis.
Q48315175	Stat3 Controls Cell Movements during Zebrafish Gastrulation
Q42730342	Stimulation of superficial zone protein accumulation by hedgehog and Wnt signaling in surface zone bovine articular chondrocytes
Q42526521	Strict correlation between uPAR and plakoglobin expression in pemphigus vulgaris
Q35586235	Structural dynamics and inhibitor searching for Wnt-4 protein using comparative computational studies
Q30757285	Subcellular localization of beta-catenin and cadherin expression in the cap-stage enamel organ of the mouse molar
Q42665882	Sulf1 has ligand-dependent effects on canonical and non-canonical Wnt signalling
Q24678046	Supervillin (p205): A novel membrane-associated, F-actin-binding protein in the villin/gelsolin superfamily
Q30417661	Suppression of Bmp4 signaling by the zinc-finger repressors Osr1 and Osr2 is required for Wnt/β-catenin-mediated lung specification in Xenopus.
Q40241743	Suppression of cyclic GMP-dependent protein kinase is essential to the Wnt/cGMP/Ca2+ pathway
Q42809920	Suppression of glycogen synthase kinase activity is not sufficient for leukemia enhancer factor-1 activation
Q43655383	Suppression of occurrence and advancement of beta-catenin-accumulated crypts, possible premalignant lesions of colon cancer, by selective cyclooxygenase-2 inhibitor, celecoxib
Q33787860	Symplekin, a constitutive protein of karyo- and cytoplasmic particles involved in mRNA biogenesis in Xenopus laevis oocytes
Q24291365	Synergistic activation of the Wnt signaling pathway by Dvl and casein kinase Iepsilon
Q34113095	Synergistic induction of tumor antigens by Wnt-1 signaling and retinoic acid revealed by gene expression profiling
Q46021076	Synthetic recording and in situ readout of lineage information in single cells.
Q54494632	Systematic peptide array-based delineation of the differential beta-catenin interaction with Tcf4, E-cadherin, and adenomatous polyposis coli.
Q33666789	T cell factor 1 initiates the T helper type 2 fate by inducing the transcription factor GATA-3 and repressing interferon-gamma.
Q35172187	T cell factor-1 negatively regulates expression of IL-17 family of cytokines and protects mice from experimental autoimmune encephalomyelitis
Q36333561	T cell factor-activated transcription is not sufficient to induce anchorage-independent growth of epithelial cells expressing mutant beta-catenin
Q36029963	T-cell factor 4 (Tcf7l2) maintains proliferative compartments in zebrafish intestine
Q24319158	T-cell factor-4-dependent up-regulation of fibronectin is involved in fibroblast growth factor-2-induced tube formation by endothelial cells
Q34634821	T-cell factors: turn-ons and turn-offs
Q33755135	TCF transcription factors: molecular switches in carcinogenesis
Q28511229	TCF-4 binds beta-catenin and is expressed in distinct regions of the embryonic brain and limbs
Q26742019	TCF/LEF Transcription Factors: An Update from the Internet Resources
Q41684115	TCF/LEF factor earn their wings
Q38048246	TCF/LEFs and Wnt signaling in the nucleus.
Q33708229	TCF7L1 promotes skin tumorigenesis independently of β-catenin through induction of LCN2.
Q28589957	TCF7L2 modulates glucose homeostasis by regulating CREB- and FoxO1-dependent transcriptional pathway in the liver
Q47926649	TCF: transcriptional activator or repressor?
Q33701577	TIEG1 modulates β-catenin sub-cellular localization and enhances Wnt signaling in bone
Q39565699	TLE3 is a dual-function transcriptional coregulator of adipogenesis
Q55403164	TMEM59 potentiates Wnt signaling by promoting signalosome formation.
Q34032260	Targeted inactivation of CTNNB1 reveals unexpected effects of beta-catenin mutation
Q38569786	Targeting Wnt signaling in colorectal cancer. A Review in the Theme: Cell Signaling: Proteins, Pathways and Mechanisms
Q34153051	Targeting the oncogenic protein beta-catenin to enhance chemotherapy outcome against solid human cancers
Q44414434	Tcf-1 expression during Xenopus development
Q35079614	Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin.
Q38290924	Tcf3 functions as a steady-state limiter of transcriptional programs of mouse embryonic stem cell self-renewal
Q57477378	Tcf7l1 directly regulates cardiomyocyte differentiation in embryonic stem cells
Q38533900	Tcf7l1 is required for spinal cord progenitor maintenance
Q50038152	Tcf7l1 promotes transcription of Kruppel-likefactor 4 during Xenopus embryogenesis.
Q39696960	Teashirt is required for transcriptional repression mediated by high Wingless levels.
Q36914679	Telomeres, a busy platform for cell signaling.
Q28215883	The APC gene in colorectal cancer
Q42478800	The APC protein binds to A/T rich DNA sequences
Q41967300	The C-terminal domain of armadillo binds to hypophosphorylated teashirt to modulate wingless signalling in Drosophila
Q28144201	The C-terminal transactivation domain of beta-catenin is necessary and sufficient for signaling by the LEF-1/beta-catenin complex in Xenopus laevis
Q28139281	The F-box: a new motif for ubiquitin dependent proteolysis in cell cycle regulation and signal transduction
Q47865464	The HMG-box transcription factor XTcf-4 demarcates the forebrain-midbrain boundary
Q38015576	The Hippo signaling pathway and stem cell biology
Q31113643	The LIM-only protein FHL2 interacts with beta-catenin and promotes differentiation of mouse myoblasts
Q24522545	The Mdm2 oncoprotein interacts with the cell fate regulator Numb
Q33855576	The Notch-2 gene is regulated by Wnt signaling in cultured colorectal cancer cells
Q26741388	The Role of the C-Clamp in Wnt-Related Colorectal Cancers
Q50336935	The TAK1-NLK-MAPK-related pathway antagonizes signalling between beta-catenin and transcription factor TCF.
Q34711963	The TCF C-clamp DNA binding domain expands the Wnt transcriptome via alternative target recognition
Q37809110	The Wnt /β-catenin signaling pathway in the adult neurogenesis
Q26748942	The Wnt Target Gene L1 in Colon Cancer Invasion and Metastasis
Q49693008	The Wnt Transcriptional Switch: TLE Removal or Inactivation?
Q34192072	The Wnt signaling pathway and its role in tumor development
Q37039789	The Wnt signaling pathway in familial exudative vitreoretinopathy and Norrie disease
Q52654686	The Wnt signalling cascade and the adherens junction complex in craniopharyngioma tumorigenesis.
Q39446727	The Wnt/Wg signal transducer beta-catenin controls fibronectin expression
Q43996883	The Wnt/calcium pathway activates NF-AT and promotes ventral cell fate in Xenopus embryos
Q30440709	The Xenopus Nieuwkoop center and Spemann-Mangold organizer share molecular components and a requirement for maternal Wnt activity
Q22003989	The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors
Q37572181	The activation of beta-catenin by Wnt signaling mediates the effects of histone deacetylase inhibitors
Q30427620	The adenomatous polyposis coli (APC) tumor suppressor
Q33850066	The adenomatous polyposis coli protein
Q24673748	The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the beta-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling
Q28535721	The antihelmintic drug pyrvinium pamoate targets aggressive breast cancer
Q52566182	The armadillo family of structural proteins.
Q38266405	The ascidian pigmented sensory organs: structures and developmental programs
Q74286666	The beta-catenin--TCF-1 pathway ensures CD4(+)CD8(+) thymocyte survival
Q28243220	The beta-catenin/T-cell factor/lymphocyte enhancer factor signaling pathway is required for normal and stress-induced cardiac hypertrophy
Q24314491	The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells
Q28580717	The cadherin-catenin complex is expressed alternately with the adenomatous polyposis coli protein during rat incisor amelogenesis
Q36535617	The canonical Wnt signalling pathway and its APC partner in colon cancer development
Q22009416	The catenin p120(ctn) interacts with Kaiso, a novel BTB/POZ domain zinc finger transcription factor
Q24534469	The chromatin remodelling factor Brg-1 interacts with beta-catenin to promote target gene activation
Q27639186	The coiled coil region (amino acids 129-250) of the tumor suppressor protein adenomatous polyposis coli (APC). Its structure and its interaction with chromosome maintenance region 1 (Crm-1)
Q29615176	The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway
Q28141823	The deubiquitinating enzyme Fam interacts with and stabilizes beta-catenin
Q33833342	The dual role of cytoskeletal anchor proteins in cell adhesion and signal transduction
Q34185421	The establishment of Spemann's organizer and patterning of the vertebrate embryo
Q36515479	The evolving roles of canonical WNT signaling in stem cells and tumorigenesis: implications in targeted cancer therapies
Q33922881	The hepatocyte growth factor/Met pathway in development, tumorigenesis, and B-cell differentiation.
Q27863647	The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin.
Q24516566	The human LEF-1 gene contains a promoter preferentially active in lymphocytes and encodes multiple isoforms derived from alternative splicing
Q41671398	The importance of the E-cadherin-catenin complex in the maintenance of intestinal epithelial homoeostasis: more than intercellular glue?
Q39526669	The influence of Leucine-rich amelogenin peptide on MSC fate by inducing Wnt10b expression
Q24297804	The inner nuclear membrane protein emerin regulates beta-catenin activity by restricting its accumulation in the nucleus
Q34838428	The ins and outs of APC and beta-catenin nuclear transport
Q36671003	The intercalated disk protein, mXinalpha, is capable of interacting with beta-catenin and bundling actin filaments [corrected].
Q28214488	The intracellular domain of cadherin-11 is not required for the induction of cell aggregation, adhesion or gap-junction formation
Q39994007	The intratumoral distribution of nuclear beta-catenin is a prognostic marker in colon cancer
Q33785937	The juxtamembrane domain of cadherin regulates integrin-mediated adhesion and neurite outgrowth
Q24323107	The kinase TNIK is an essential activator of Wnt target genes
Q28476157	The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/β-catenin coactivators essential for intestinal homeostasis
Q24672469	The links between axin and carcinogenesis
Q26865781	The many faces and functions of β-catenin
Q35071119	The mitogen-activated protein kinase kinase kinase kinase GCKR positively regulates canonical and noncanonical Wnt signaling in B lymphocytes.
Q29620489	The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling
Q33540073	The oncogenic activation of beta-catenin
Q47887895	The planarian TCF/LEF factor Smed-tcf1 is required for the regeneration of dorsal-lateral neuronal subtypes
Q41837031	The responses of neural stem cells to the level of GSK-3 depend on the tissue of origin
Q28511400	The role of Axin2 in calvarial morphogenesis and craniosynostosis
Q41895615	The role of Pygo2 for Wnt/ß-catenin signaling activity during intestinal tumor initiation and progression
Q28082213	The role of WNT signaling in adult ovarian folliculogenesis
Q37859090	The role of WNT10B in physiology and disease
Q77198220	The role of maternal VegT in establishing the primary germ layers in Xenopus embryos
Q33546894	The role of the cell-adhesion molecule E-cadherin as a tumour-suppressor gene
Q24794970	The role of the ubiquitination-proteasome pathway in breast cancer: use of mouse models for analyzing ubiquitination processes
Q42803494	The thioredoxin-related redox-regulating protein nucleoredoxin inhibits Wnt-beta-catenin signalling through dishevelled
Q30175138	The tight junction protein ZO-1 and an interacting transcription factor regulate ErbB-2 expression
Q30432515	The tumor-associated EpCAM regulates morphogenetic movements through intracellular signaling.
Q24539724	The tumor-suppressor function of E-cadherin
Q38068918	The way Wnt works: components and mechanism.
Q37441297	The wnt pathway: a macrophage effector molecule that triggers inflammation
Q28279593	The β-catenin destruction complex
Q88965519	Therapeutic Potency of Nanoformulations of siRNAs and shRNAs in Animal Models of Cancers
Q34276643	Three decades of Wnts: a personal perspective on how a scientific field developed
Q27743283	Three-dimensional structure of the armadillo repeat region of beta-catenin
Q24338810	Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation
Q35195479	Tissue- and stage-specific modulation of Wingless signaling by the segment polarity gene lines
Q42475621	Tissue-specific regulation of the ecto-5'-nucleotidase promoter. Role of the camp response element site in mediating repression by the upstream regulatory region
Q41462850	Towards a unified model of tumor suppression: lessons learned from the human patched gene
Q48145532	Transcription factor AP-2β suppresses cervical cancer cell proliferation by promoting the degradation of its interaction partner β-catenin
Q34167954	Transcription factor regulation of B lineage commitment
Q33300355	Transcriptional program induced by Wnt protein in human fibroblasts suggests mechanisms for cell cooperativity in defining tissue microenvironments
Q33745059	Transcriptional regulation in Xenopus: a bright and froggy future
Q89357274	Transcriptional regulation of murine natural killer cell development, differentiation and maturation
Q38077691	Transcriptional regulators of hepatic gluconeogenesis.
Q24316983	Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors
Q22010386	Transforming growth factor-beta-stimulated clone-22 is a member of a family of leucine zipper proteins that can homo- and heterodimerize and has transcriptional repressor activity
Q42056049	Transgenic analysis of signaling pathways required for Xenopus tadpole spinal cord and muscle regeneration
Q44624422	Translocation of β-catenin into the nucleus independent of interactions with FG-rich nucleoporins
Q61795846	Tryptophan-kynurenine pathway attenuates β-catenin-dependent pro-parasitic role of STING-TICAM2-IRF3-IDO1 signalosome in Toxoplasma gondii infection
Q37545014	Tuberous sclerosis complex inactivation disrupts melanogenesis via mTORC1 activation.
Q28833737	Tubulin is a molecular target of the Wnt-activating chemical probe
Q36364880	Tumor suppressor PTEN inhibits nuclear accumulation of beta-catenin and T cell/lymphoid enhancer factor 1-mediated transcriptional activation
Q40525491	Tumor-associated E-cadherin mutations do not induce Wnt target gene expression, but affect E-cadherin repressors.
Q47785951	Tumor-suppressive miR-145 co-repressed by TCF4-β-catenin and PRC2 complexes forms double-negative regulation loops with its negative regulators in colorectal cancer
Q58197500	Tumour-associated E-cadherin mutations alter cellular morphology, decrease cellular adhesion and increase cellular motility
Q90006479	Two is a Crowd: Two is a Crowd: On the Enigmatic Etiopathogenesis of Conjoined Twinning
Q24314604	Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse
Q37301937	Two variants on T2DM susceptible gene HHEX are associated with CRC risk in a Chinese population
Q34691362	Tyrosine phosphorylation of LRP6 by Src and Fer inhibits Wnt/β-catenin signalling
Q41110999	Uncoupling of XB/U-cadherin-catenin complex formation from its function in cell-cell adhesion
Q90283931	Unraveling Heterogeneity in Epithelial Cell Fates of the Mammary Gland and Breast Cancer
Q38446601	Up-regulation of Wnt-1 and beta-catenin production in patients with advanced metastatic prostate carcinoma: potential pathogenetic and prognostic implications.
Q59799591	Usp16 modulates Wnt signaling in primary tissues through Cdkn2a regulation
Q40554913	VegT activation of the early zygotic gene Xnr5 requires lifting of Tcf-mediated repression in the Xenopus blastula
Q38782671	Vertebrate Axial Patterning: From Egg to Asymmetry
Q34097370	Viral FLIP enhances Wnt signaling downstream of stabilized beta-catenin, leading to control of cell growth
Q22008485	WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors
Q24608963	WISP-1 is a Wnt-1- and beta-catenin-responsive oncogene
Q47299786	WNT Signaling in Cardiac and Vascular Disease.
Q34619783	WNT signaling and lymphocyte development
Q39154095	WNT signalling events near the cell membrane and their pharmacological targeting for the treatment of cancer.
Q47827483	WNT signalling molecules act in axis formation in the diploblastic metazoan Hydra.
Q33543971	WNT targets. Repression and activation
Q34918244	WNT-3A modulates articular chondrocyte phenotype by activating both canonical and noncanonical pathways
Q37635264	WNT/Frizzled signalling: receptor-ligand selectivity with focus on FZD-G protein signalling and its physiological relevance: IUPHAR Review 3
Q58733235	WNT2 is necessary for normal prostate gland cyto-differentiation and modulates prostate growth in an FGF10 dependent manner
Q88268314	Wingless Signaling: A Genetic Journey from Morphogenesis to Metastasis
Q39242257	Wnt Signaling Polarizes C. elegans Asymmetric Cell Divisions During Development
Q39306017	Wnt Signaling in Normal and Malignant Stem Cells
Q36948097	Wnt and Frizzled RNA expression in human mesenchymal and embryonic (H7) stem cells
Q40554562	Wnt and beta-catenin signaling target the expression of ecto-5'-nucleotidase and increase extracellular adenosine generation
Q37724188	Wnt and the Wnt signaling pathway in bone development and disease
Q52196135	Wnt meeting 1996.
Q33712511	Wnt signaling and dorso-ventral axis specification in vertebrates
Q36094235	Wnt signaling and transcriptional control of Siamois in Xenopus embryos
Q52102720	Wnt signaling during development of the gastrointestinal tract.
Q35209932	Wnt signaling in Xenopus embryos inhibits bmp4 expression and activates neural development
Q38078915	Wnt signaling in normal and malignant hematopoiesis
Q35084283	Wnt signaling in the thymus
Q36629761	Wnt signaling in vertebrate axis specification
Q28585177	Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism
Q40978338	Wnt signaling stabilizes the dual-function protein beta-catenin in diverse cell types
Q24337717	Wnt signaling through inhibition of β-catenin degradation in an intact Axin1 complex
Q40898812	Wnt signaling: the β-cat(enin)'s meow
Q38529134	Wnt signaling: why is everything so negative?
Q29619273	Wnt signalling and its impact on development and cancer
Q41359112	Wnt signalling goes nuclear
Q34589148	Wnt signalling induces accumulation of phosphorylated β-catenin in two distinct cytosolic complexes
Q28593773	Wnt signalling induces maturation of Paneth cells in intestinal crypts
Q40609090	Wnt signalling inhibits neural differentiation of embryonic stem cells by controlling bone morphogenetic protein expression
Q28366892	Wnt signals are transmitted through N-terminally dephosphorylated beta-catenin
Q33917414	Wnt some lose some: transcriptional governance of stem cells by Wnt/β-catenin signaling
Q39397771	Wnt target genes and where to find them.
Q34997437	Wnt won the war: antagonistic role of Wnt over Shh controls dorso-ventral patterning of the vertebrate neural tube
Q47216766	Wnt, RSPO and Hippo Signalling in the Intestine and Intestinal Stem Cells
Q36044404	Wnt, stem cells and cancer in the intestine
Q33786436	Wnt-1 induces growth, cytosolic beta-catenin, and Tcf/Lef transcriptional activation in Rat-1 fibroblasts
Q36370019	Wnt-1 signaling inhibits apoptosis by activating beta-catenin/T cell factor-mediated transcription
Q40723420	Wnt-3A enhances bone morphogenetic protein-2-mediated chondrogenesis of murine C3H10T1/2 mesenchymal cells
Q24299786	Wnt-4 activates the canonical beta-catenin-mediated Wnt pathway and binds Frizzled-6 CRD: functional implications of Wnt/beta-catenin activity in kidney epithelial cells
Q38221361	Wnt-Notch signalling crosstalk in development and disease.
Q30539869	Wnt-dependent epithelial transitions drive pharyngeal pouch formation.
Q36712615	Wnt-induced deubiquitination FoxM1 ensures nucleus β-catenin transactivation
Q38797398	Wnt-induced transcriptional activation is exclusively mediated by TCF/LEF.
Q33389500	Wnt-reporter expression pattern in the mouse intestine during homeostasis
Q37318020	Wnt/Rspondin/β-catenin signals control axonal sorting and lineage progression in Schwann cell development
Q39286193	Wnt/beta-catenin pathway: modulating anticancer immune response
Q34013834	Wnt/beta-catenin signaling
Q24597197	Wnt/beta-catenin signaling and small molecule inhibitors
Q73958568	Wnt/beta-catenin signaling induces the expression and activity of betaTrCP ubiquitin ligase receptor
Q28585255	Wnt/frizzled-2 signaling induces aggregation and adhesion among cardiac myocytes by increased cadherin-beta-catenin complex
Q90675233	Wnt/β-Catenin Signaling and Obesity
Q34972224	Wnt/β-catenin Pathway Modulates the Sensitivity of the Mutant FLT3 Receptor Kinase Inhibitors in a GSK-3β Dependent Manner
Q28511693	Wnt/β-catenin and Bmp signals control distinct sets of transcription factors in cardiac progenitor cells
Q26823272	Wnt/β-catenin signaling and disease
Q39319057	Wnt/β-catenin signaling in adult mammalian epithelial stem cells
Q28269116	Wnt/β-catenin signalling in prostate cancer
Q37025924	Wnt/β-catenin signalling induces MLL to create epigenetic changes in salivary gland tumours
Q55457524	Wnt/β-catenin signalling is necessary for gut differentiation in a marine annelid, Platynereis dumerilii.
Q49430709	Wnt3a expression is associated with poor prognosis of esophageal squamous cell carcinoma
Q28509058	Wnt3a-/--like phenotype and limb deficiency in Lef1(-/-)Tcf1(-/-) mice
Q36058721	Wnt3a-stimulated LRP6 phosphorylation is dependent upon arginine methylation of G3BP2.
Q35944752	Wnt5a and Wnt11 are essential for second heart field progenitor development.
Q79358419	Wnt5a inhibits B cell proliferation and functions as a tumor suppressor in hematopoietic tissue
Q30576111	Wnt7a stimulates myogenic stem cell motility and engraftment resulting in improved muscle strength.
Q38325684	XIC is required for Siamois activity and dorsoanterior development
Q41824181	XTsh3 is an essential enhancing factor of canonical Wnt signaling in Xenopus axial determination
Q30651588	Xarvcf, Xenopus member of the p120 catenin subfamily associating with cadherin juxtamembrane region
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P356	DOI	10.1016/S0092-8674(00)80112-9
P3181	OpenCitations bibliographic resource ID	1407579
P698	PubMed publication ID	8756721

P50	author	Jeroen P Roose	Q88812608
P2093	author name string	H. Clevers
		M. Oosterwegel
		M. Molenaar
		O. Destrée
		M. van de Wetering
		V. Korinek
		J. Peterson-Maduro
		J. Roose
		S. Godsave
P2860	cites work	A gene family of HMG-box transcription factors with homology to TCF-1	Q24301926
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		Extensive alternative splicing and dual promoter usage generate Tcf-1 protein isoforms with differential transcription control properties	Q24650844
		dishevelled and armadillo act in the wingless signalling pathway in Drosophila	Q28237239
		A repeating amino acid motif shared by proteins with diverse cellular roles	Q28237358
		A homolog of the armadillo protein in Drosophila (plakoglobin) associated with E-cadherin	Q28252615
		LEF-1, a gene encoding a lymphoid-specific protein with an HMG domain, regulates T-cell receptor alpha enhancer function [corrected]	Q28268708
		A thymus-specific member of the HMG protein family regulates the human T cell receptor C alpha enhancer	Q28271385
		The nuclear localization signal of lymphoid enhancer factor-1 is recognized by two differentially expressed Srp1-nuclear localization sequence receptor proteins	Q28278924
		Cloning of murine TCF-1, a T cell-specific transcription factor interacting with functional motifs in the CD3-epsilon and T cell receptor alpha enhancers	Q28508568
		Transmembrane control of cadherin-mediated cell adhesion: a 94 kDa protein functionally associated with a specific region of the cytoplasmic domain of E-cadherin	Q28589140
		Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice	Q29618462
		A common ancestor of the mammalian transcription factors TCF-1 and TCF-1 alpha/LEF-1 expressed in chicken T cells	Q33212951
		Overexpression of cadherins and underexpression of beta-catenin inhibit dorsal mesoderm induction in early Xenopus embryos	Q34292991
		Ectopic expression of the proto-oncogene int-1 in Xenopus embryos leads to duplication of the embryonic axis.	Q34507567
		Induction of a secondary body axis in Xenopus by antibodies to beta-catenin	Q36233414
		Embryonic axis induction by the armadillo repeat domain of beta-catenin: evidence for intracellular signaling	Q36235397
		The vertebrate adhesive junction proteins beta-catenin and plakoglobin and the Drosophila segment polarity gene armadillo form a multigene family with similar properties	Q36531649
		LEF-1 contains an activation domain that stimulates transcription only in a specific context of factor-binding sites.	Q40875094
		Dynamic and differential Oct-1 expression during early Xenopus embryogenesis: persistence of Oct-1 protein following down-regulation of the RNA.	Q41356715
		Molecular nature of Spemann's organizer: the role of the Xenopus homeobox gene goosecoid	Q42739682
		Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryos	Q44061010
		The hLEF/TCF-1 alpha HMG protein contains a context-dependent transcriptional activation domain that induces the TCR alpha enhancer in T cells	Q46121592
		Molecular mechanisms of Spemann's organizer formation: conserved growth factor synergy between Xenopus and mouse	Q46227290
		Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos	Q48074534
		Expression cloning of Siamois, a Xenopus homeobox gene expressed in dorsal-vegetal cells of blastulae and able to induce a complete secondary axis.	Q48074611
		Structure and expression of the Xenopus retinoblastoma gene	Q50790447
		Regulation of the zebrafish goosecoid promoter by mesoderm inducing factors and Xwnt1.	Q52202519
		Whole-mount immunohistochemistry on Xenopus embryos using far-red fluorescent dyes.	Q52211188
		An HMG-box-containing T-cell factor required for thymocyte differentiation.	Q59058515
		Identification and cloning of TCF-1, a T lymphocyte-specific transcription factor containing a sequence-specific HMG box	Q61772815
		The entire mesodermal mantle behaves as Spemann's organizer in dorsoanterior enhanced Xenopus laevis embryos	Q68133902
P433	issue	3
P407	language of work or name	English	Q1860
P304	page(s)	391–399
P577	publication date	1996-08-09
P1433	published in	Cell	Q655814
P1476	title	XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos
P478	volume	86

XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos

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