Alkylglycerol monooxygenase, a heterotaxy candidate gene, regulates left-right patterning via Wnt signaling

scientific article published on 06 August 2019

Alkylglycerol monooxygenase, a heterotaxy candidate gene, regulates left-right patterning via Wnt signaling is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.YDBIO.2019.07.019
P932PMC publication ID7784330
P698PubMed publication ID31398317

P2093author name stringJohn N Griffin
Mustafa K Khokha
Anna R Duncan
Andrew Robson
Florencia Del Viso
Delfina P González
P2860cites workThe left-right axis is regulated by the interplay of Coco, Xnr1 and derrière in Xenopus embryosQ24293713
Identification of the gene encoding alkylglycerol monooxygenase defines a third class of tetrahydrobiopterin-dependent enzymesQ24339407
The heterotaxy gene GALNT11 glycosylates Notch to orchestrate cilia type and laterality.Q24339579
Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin geneQ24529898
Wnt/beta-catenin signaling: components, mechanisms, and diseasesQ24630938
Strong association of de novo copy number mutations with autismQ24633543
Wnt/β-catenin signaling and diseaseQ26823272
Alkylglycerol monooxygenaseQ26825422
Wnt signaling networks in autism spectrum disorder and intellectual disabilityQ28074740
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes riskQ28270700
The transcription factor Pitx2 mediates situs-specific morphogenesis in response to left-right asymmetric signalsQ28279925
ASPM regulates Wnt signaling pathway activity in the developing brainQ28508236
Wnt5a regulates distinct signalling pathways by binding to Frizzled2Q28588878
XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryosQ28619032
Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCFQ28645084
Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetesQ29614589
Wnt proteins are lipid-modified and can act as stem cell growth factorsQ29615009
WNT and beta-catenin signalling: diseases and therapiesQ29616159
Two populations of node monocilia initiate left-right asymmetry in the mouseQ29617071
How we are shaped: the biomechanics of gastrulationQ30310766
Techniques and probes for the study of Xenopus tropicalis developmentQ33185267
Wnt3a-mediated formation of phosphatidylinositol 4,5-bisphosphate regulates LRP6 phosphorylationQ33366930
Caveolin-1 regulates dorsoventral patterning through direct interaction with beta-catenin in zebrafishQ33572533
Effect of genetic variants and traits related to glucose metabolism and their interaction with obesity on breast and colorectal cancer risk among postmenopausal womenQ33604592
The TGF-beta family member derrière is involved in regulation of the establishment of left-right asymmetryQ33756980
Cholesterol selectively activates canonical Wnt signalling over non-canonical Wnt signallingQ33908017
Transient and controllable opening of the blood-brain barrier to cytostatic and antibiotic agents by alkylglycerols in ratsQ33930507
Left-right asymmetry in the level of active Nodal protein produced in the node is translated into left-right asymmetry in the lateral plate of mouse embryos.Q34051847
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Rare copy number variations in congenital heart disease patients identify unique genes in left-right patterningQ34582831
Wnt signaling: relevance to beta-cell biology and diabetesQ34858330
The ribosome biogenesis factor Nol11 is required for optimal rDNA transcription and craniofacial development in XenopusQ35574590
Cuticle integrity and biogenic amine synthesis in Caenorhabditis elegans require the cofactor tetrahydrobiopterin (BH4).Q35579804
Regionally specific induction by the Spemann-Mangold organizerQ35778667
Catalytic residues and a predicted structure of tetrahydrobiopterin-dependent alkylglycerol mono-oxygenase.Q35832618
Embryonic axis induction by the armadillo repeat domain of beta-catenin: evidence for intracellular signalingQ36235397
Systematic evaluation of validated type 2 diabetes and glycaemic trait loci for association with insulin clearanceQ36836752
Cilia at the node of mouse embryos sense fluid flow for left-right determination via Pkd2Q37011684
Xenopus, an ideal model system to study vertebrate left-right asymmetryQ37390067
Disorders of left-right asymmetry: heterotaxy and situs inversusQ37624560
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Zebrafish prickle, a modulator of noncanonical Wnt/Fz signaling, regulates gastrulation movements.Q38520593
Structural and functional roles of ether lipidsQ39317295
Congenital Heart Disease Genetics Uncovers Context-Dependent Organization and Function of Nucleoporins at CiliaQ39424289
Porcupine-mediated lipidation is required for Wnt recognition by Wls.Q39754448
Electrochemical cues regulate assembly of the Frizzled/Dishevelled complex at the plasma membrane during planar epithelial polarization.Q39880969
The alkylglycerol monooxygenase (AGMO) gene previously involved in autism also causes a novel syndromic form of primary microcephaly in a consanguineous Saudi familyQ39901078
Synergism between the antifungal agents amphotericin B and alkyl glycerol ethersQ40285811
Wnt/β-catenin signaling directly regulates Foxj1 expression and ciliogenesis in zebrafish Kupffer's vesicleQ41432483
Formation and function of Spemann's organizerQ41689393
The forkhead protein Foxj1 specifies node-like cilia in Xenopus and zebrafish embryosQ42158837
Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish peopleQ43085753
Porcupine homolog is required for canonical Wnt signaling and gastrulation in mouse embryosQ45345860
Depletion of three BMP antagonists from Spemann's organizer leads to a catastrophic loss of dorsal structuresQ46073558
GCK, GCKR, FADS1, DGKB/TMEM195 and CDKAL1 Gene Polymorphisms in Women with Gestational Diabetes.Q48618604
RAPGEF5 Regulates Nuclear Translocation of β-Catenin.Q49378541
Wnt signaling regulates left-right axis formation in the node of mouse embryos.Q50742886
ATP4a is required for Wnt-dependent Foxj1 expression and leftward flow in Xenopus left-right development.Q50793684
Variations with modest effects have an important role in the genetic background of type 2 diabetes and diabetes-related traits.Q51351265
A two-cilia model for vertebrate left-right axis specification.Q52110477
Heterotaxia, congenital heart disease, and primary ciliary dyskinesia.Q55044037
The DIX domain targets dishevelled to actin stress fibres and vesicular membranesQ57800361
WDR5 regulates left-right patterning via chromatin dependent and independent functionsQ58590909
Identification and cloning of TCF-1, a T lymphocyte-specific transcription factor containing a sequence-specific HMG boxQ61772815
β-Catenin Has Wnt-like Activity and Mimics the Nieuwkoop Signaling Center inXenopusDorsal–Ventral PatterningQ71816780
The nodal inhibitor Coco is a critical target of leftward flow in XenopusQ84034505
Generating diploid embryos from Xenopus tropicalisQ84943564
P4510describes a project that usesImageJQ1659584
P433issue1
P1104number of pages7
P304page(s)1-7
P577publication date2019-08-06
P1433published inDevelopmental BiologyQ3025402
P1476titleAlkylglycerol monooxygenase, a heterotaxy candidate gene, regulates left-right patterning via Wnt signaling
P478volume456

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