Abstract is: Johannes (Hans) Carolus Clevers (born 27 March 1957) is a Dutch molecular geneticist, cell biologist and stem cell researcher. He became the Head of Pharma, Research and Early Development, and a member of the Corporate Executive Committee, of the Swiss healthcare company Roche in 2022. Previously, he headed a research group at the Hubrecht Institute for Developmental Biology and Stem Cell Research and at the ; he remained as an advisor and guest scientist or visiting researcher to both groups. He is also a Professor in Molecular Genetics at the University of Utrecht.
| human | Q5 |
| P5463 | AE member ID | Clevers_Hans |
| P6231 | BDELIS ID | 93002 |
| P2862 | Catalogus Professorum Academiae Rheno-Traiectinae ID | 401 |
| P646 | Freebase ID | /m/0j66qfy |
| P6282 | French Academy of Sciences member ID | C/hans-clevers |
| P2600 | Geni.com profile ID | 6000000128844559845 |
| P227 | GND ID | 1260863697 |
| P1960 | Google Scholar author ID | jTAHhTQAAAAJ |
| P1741 | GTAA ID | 212760 |
| P213 | ISNI | 0000000043961208 |
| P244 | Library of Congress authority ID | no93034656 |
| P7449 | NARCIS researcher ID | PRS1237399 |
| P5380 | National Academy of Sciences member ID | 20019189 |
| P8189 | National Library of Israel J9U ID | 987007414192605171 |
| P1006 | Nationale Thesaurus voor Auteursnamen ID | 07164282X |
| P856 | official website | https://www.hubrecht.eu/research-groups/clevers-group/ |
| P496 | ORCID iD | 0000-0002-3077-5582 |
| P1053 | ResearcherID | F-9185-2013 |
| P1153 | Scopus author ID | 35594209900 |
| P214 | VIAF ID | 46334721 |
| P10832 | WorldCat Entities ID | E39PBJy4jCkW34Pc9r39Xjvrbd |
| P2002 | X username | hansclevers |
| P512 | academic degree | Doctor of Philosophy | Q752297 |
| P166 | award received | Dr A.H. Heineken Prize for Medicine | Q278248 |
| Spinoza Prize | Q1131142 | ||
| Keio Medical Science Prize | Q1324940 | ||
| Leopold Griffuel Prize | Q1879505 | ||
| Meyenburg Prize | Q1926301 | ||
| Clarivate Citation Laureates | Q7795894 | ||
| Louis-Jeantet Prize for Medicine | Q14324534 | ||
| Foreign Member of the Royal Society | Q14906020 | ||
| Pour le Mérite for Sciences and Arts order | Q15056034 | ||
| Breakthrough Prize in Life Sciences | Q5019489 | ||
| Körber European Science Prize | Q6453962 | ||
| Ernst Jung Prize for Medicine | Q29886440 | ||
| Fellow of the American Academy of Arts and Sciences | Q52382875 | ||
| P27 | country of citizenship | Kingdom of the Netherlands | Q29999 |
| P69 | educated at | Utrecht University | Q221653 |
| P108 | employer | Utrecht University | Q221653 |
| Hubrecht Institute | Q2512544 | ||
| P734 | family name | Clevers | Q66247053 |
| Clevers | Q66247053 | ||
| Clevers | Q66247053 | ||
| P101 | field of work | molecular genetics | Q210506 |
| P735 | given name | Hans | Q632842 |
| Hans | Q632842 | ||
| P463 | member of | Royal Society | Q123885 |
| Academia Europaea | Q337234 | ||
| American Academy of Arts and Sciences | Q463303 | ||
| Royal Netherlands Academy of Arts and Sciences | Q253439 | ||
| National Academy of Sciences | Q270794 | ||
| P106 | occupation | physician | Q39631 |
| university teacher | Q1622272 | ||
| geneticist | Q3126128 | ||
| molecular biologist | Q15839206 | ||
| P5008 | on focus list of Wikimedia project | WikiProject COVID-19 | Q87748614 |
| P21 | sex or gender | male | Q6581097 |
| P8687 | social media followers | 16692 | |
| P10 | video | License: CC BY-SA 3.0 nl Artists:
VPRO This work is copyrighted. Attribution is required. |
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| Q38120218 | Concise review: the yin and yang of intestinal (cancer) stem cells and their progenitors |
| Q47203432 | Consensus molecular subtypes of colorectal cancer are recapitulated in in vitro and in vivo models |
| Q24336272 | Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma |
| Q34237942 | Controlled gene expression in primary Lgr5 organoid cultures |
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| Q39751765 | Conversion of metaplastic Barrett's epithelium into post-mitotic goblet cells by gamma-secretase inhibition |
| Q59806075 | Correction for Muncan et al., "Rapid Loss of Intestinal Crypts upon Conditional Deletion of the Wnt/Tcf-4 Target Gene c-" |
| Q42323406 | Correction: The Leukemia-Associated Mllt10/Af10-Dot1l Are Tcf4/β-Catenin Coactivators Essential for Intestinal Homeostasis |
| Q50106174 | Corrigendum: Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors |
| Q28304418 | Crypt stem cells as the cells-of-origin of intestinal cancer |
| Q47398290 | Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation |
| Q33216786 | Cyclin D1 is not an immediate target of beta-catenin following Apc loss in the intestine |
| Q42003181 | Cyclin D2-cyclin-dependent kinase 4/6 is required for efficient proliferation and tumorigenesis following Apc loss |
| Q112305681 | Cysteamine-bicalutamide combination therapy corrects proximal tubule phenotype in cystinosis |
| Q31110759 | De Novo Prediction of Stem Cell Identity using Single-Cell Transcriptome Data |
| Q47961996 | De novo crypt formation and juvenile polyposis on BMP inhibition in mouse intestine |
| Q99248364 | Deficiency of the SMOC2 matricellular protein impairs bone healing and produces age-dependent bone loss |
| Q92368843 | Defining Adult Stem Cell Function at Its Simplest: The Ability to Replace Lost Cells through Mitosis |
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| Q92681827 | Defining the Identity and Dynamics of Adult Gastric Isthmus Stem Cells |
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| Q38555324 | Development and application of human adult stem or progenitor cell organoids |
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| Q37683769 | Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer. |
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| Q33770079 | Efficient double fragmentation ChIP-seq provides nucleotide resolution protein-DNA binding profiles |
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| Q36362266 | EphB/EphrinB receptors and Wnt signaling in colorectal cancer |
| Q63407206 | Erratum: EphB receptor activity suppresses colorectal cancer progression |
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| Q99418586 | Establishment of patient-derived cancer organoids for drug-screening applications |
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| Q24310750 | Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling |
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| Q34291885 | Lineage tracing reveals Lgr5+ stem cell activity in mouse intestinal adenomas |
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| Q41768027 | Lipid-mediated Wnt protein stabilization enables serum-free culture of human organ stem cells. |
| Q35595940 | Live and let die in the intestinal epithelium |
| Q63407208 | Live and let die in the intestinal epithelium [Curr. Opin. Cell Biol. 15 (2003) 763] |
| Q34642744 | Live imaging of astrocyte responses to acute injury reveals selective juxtavascular proliferation. |
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| Q89998661 | Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids |
| Q36482250 | Long-Term In Vitro Expansion of Salivary Gland Stem Cells Driven by Wnt Signals |
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| Q112757037 | Long-term culture, genetic manipulation and xenotransplantation of human normal and breast cancer organoids |
| Q64244995 | Long-term expanding human airway organoids for disease modeling |
| Q93115578 | Long-term expansion and differentiation of adult murine epidermal stem cells in 3D organoid cultures |
| Q28587140 | Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration |
| Q34414895 | Loss of syntaxin 3 causes variant microvillus inclusion disease |
| Q38733090 | Loss of the Wnt receptor frizzled 7 in the mouse gastric epithelium is deleterious and triggers rapid repopulation in vivo |
| Q24302528 | Loss of the tumor suppressor CYLD enhances Wnt/beta-catenin signaling through K63-linked ubiquitination of Dvl |
| Q34258498 | Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling |
| Q39744343 | MAP3K1 functionally interacts with Axin1 in the canonical Wnt signalling pathway. |
| Q50527243 | MET Signaling Mediates Intestinal Crypt-Villus Development, Regeneration, and Adenoma Formation and Is Promoted by Stem Cell CD44 Isoforms. |
| Q93129260 | MET Signaling Overcomes Epidermal Growth Factor Receptor Inhibition in Normal and Colorectal Cancer Stem Cells Causing Drug Resistance |
| Q24296287 | MO25alpha/beta interact with STRADalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasm |
| Q54447794 | Many inflammatory bowel disease risk loci include regions that regulate gene expression in immune cells and the intestinal epithelium. |
| Q34332458 | Mapping early fate determination in Lgr5+ crypt stem cells using a novel Ki67-RFP allele |
| Q36973782 | Mapping the consequence of Notch1 proteolysis in vivo with NIP-CRE |
| Q47351515 | Measuring mutation accumulation in single human adult stem cells by whole-genome sequencing of organoid cultures |
| Q35013616 | Microbiota controls the homeostasis of glial cells in the gut lamina propria |
| Q40629903 | Model organoids provide new research opportunities for ductal pancreatic cancer |
| Q24657457 | Modeling Development and Disease with Organoids |
| Q93372971 | Modeling Human Digestive Diseases With CRISPR-Cas9-Modified Organoids |
| Q36842030 | Modeling pancreatic cancer with organoids |
| Q89267428 | Modelling Cryptosporidium infection in human small intestinal and lung organoids |
| Q63804650 | Modelling cancer immunomodulation using epithelial organoid cultures |
| Q112642043 | Modelling of primary ciliary dyskinesia using patient-derived airway organoids |
| Q84962844 | Monoclonal antibodies against Lgr5 identify human colorectal cancer stem cells |
| Q46256873 | Mouse Model of Alagille Syndrome and Mechanisms of Jagged1 Missense Mutations. |
| Q42811211 | Mst4 and Ezrin induce brush borders downstream of the Lkb1/Strad/Mo25 polarization complex |
| Q40071670 | Mule Regulates the Intestinal Stem Cell Niche via the Wnt Pathway and Targets EphB3 for Proteasomal and Lysosomal Degradation |
| Q89918990 | Mutational signature in colorectal cancer caused by genotoxic pks+ E. coli |
| Q28591197 | Myc deletion rescues Apc deficiency in the small intestine |
| Q28640916 | Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors |
| Q36038866 | Neural stem cells for diabetes cell-based therapy |
| Q98578686 | Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo |
| Q37633867 | Niche-independent high-purity cultures of Lgr5+ intestinal stem cells and their progeny |
| Q88721108 | Notch ligand Dll1 mediates cross-talk between mammary stem cells and the macrophageal niche |
| Q34981596 | OLFM4 is a robust marker for stem cells in human intestine and marks a subset of colorectal cancer cells |
| Q34282882 | On the biomechanics of stem cell niche formation in the gut--modelling growing organoids |
| Q44943545 | Oncogene-inducible organoids as a miniature platform to assess cancer characteristics |
| Q91625157 | Ongoing chromosomal instability and karyotype evolution in human colorectal cancer organoids |
| Q36965441 | Optimality in the development of intestinal crypts |
| Q91750889 | Oral Mucosal Organoids as a Potential Platform for Personalized Cancer Therapy |
| Q61032374 | Organoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic Cancer |
| Q39035547 | Organoid culture systems for prostate epithelial and cancer tissue. |
| Q34545103 | Organoid cultures derived from patients with advanced prostate cancer |
| Q38198433 | Organoid cultures for the analysis of cancer phenotypes |
| Q91583350 | Organoid cultures from normal and cancer-prone human breast tissues preserve complex epithelial lineages |
| Q90688995 | Organoid cultures of early-onset colorectal cancers reveal distinct and rare genetic profiles |
| Q34456438 | Organoid models of human and mouse ductal pancreatic cancer |
| Q40877873 | Organoids as Model for Infectious Diseases: Culture of Human and Murine Stomach Organoids and Microinjection of Helicobacter Pylori. |
| Q92097336 | Organoids in immunological research |
| Q38965862 | Organoids: Modeling Development and the Stem Cell Niche in a Dish. |
| Q38373329 | Origins of lymphatic and distant metastases in human colorectal cancer. |
| Q57456360 | PRMT6 Regulates RAS/RAF Binding and MEK/ERK-Mediated Cancer Stemness Activities in Hepatocellular Carcinoma through CRAF Methylation |
| Q91824416 | Pancreatic cancer organoids recapitulate disease and allow personalized drug screening |
| Q91202976 | Paneth Cells Respond to Inflammation and Contribute to Tissue Regeneration by Acquiring Stem-like Features through SCF/c-Kit Signaling |
| Q30582106 | Paneth cell extrusion and release of antimicrobial products is directly controlled by immune cell-derived IFN-γ. |
| Q34425223 | Paneth cells |
| Q29616197 | Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts |
| Q91147891 | Patient-Derived Head and Neck Cancer Organoids Recapitulate EGFR Expression Levels of Respective Tissues and Are Responsive to EGFR-Targeted Photodynamic Therapy |
| Q96585273 | Patient-Derived Ovarian Cancer Organoids Mimic Clinical Response and Exhibit Heterogeneous Inter- and Intrapatient Drug Responses |
| Q90616584 | Patient-derived organoids can predict response to chemotherapy in metastatic colorectal cancer patients |
| Q95924511 | Patient-derived pancreatic tumour organoids identify therapeutic responses to oncolytic adenoviruses |
| Q38774913 | Personalized Proteome Profiles of Healthy and Tumor Human Colon Organoids Reveal Both Individual Diversity and Basic Features of Colorectal Cancer |
| Q42321791 | Peyer's patch M cells derived from Lgr5(+) stem cells require SpiB and are induced by RankL in cultured "miniguts". |
| Q39784341 | Phosphatidylinositol 3-kinase signaling does not activate the wnt cascade |
| Q38259450 | Plasticity within stem cell hierarchies in mammalian epithelia |
| Q35764241 | Porcupine inhibitor suppresses paracrine Wnt-driven growth of Rnf43;Znrf3-mutant neoplasia |
| Q36428208 | Preclinical models of pancreatic ductal adenocarcinoma |
| Q50597182 | Premigratory and migratory neural crest cells are multipotent in vivo. |
| Q36238283 | Preserved genetic diversity in organoids cultured from biopsies of human colorectal cancer metastases |
| Q97684275 | Primary Intestinal Epithelial Organoid Culture |
| Q44695414 | Primary mouse small intestinal epithelial cell cultures |
| Q92304607 | Probing the Tumor Suppressor Function of BAP1 in CRISPR-Engineered Human Liver Organoids |
| Q60911613 | Profiling proliferative cells and their progeny in damaged murine hearts |
| Q50614489 | Prominin-1/CD133 marks stem cells and early progenitors in mouse small intestine. |
| Q38877277 | Prospective derivation of a living organoid biobank of colorectal cancer patients. |
| Q44703801 | Proteome changes induced by knock-down of the deubiquitylating enzyme HAUSP/USP7. |
| Q128278687 | Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine |
| Q50503381 | RNF43 germline and somatic mutation in serrated neoplasia pathway and its association with BRAF mutation. |
| Q91367455 | ROCKin' Intestinal Cell Fate: A Potential Avenue to Improve Glucose Sensitivity |
| Q24293320 | Rap2A links intestinal cell polarity to brush border formation |
| Q39126564 | Rapid loss of intestinal crypts upon conditional deletion of the Wnt/Tcf-4 target gene c-Myc |
| Q50788436 | Redundant sources of Wnt regulate intestinal stem cells and promote formation of Paneth cells. |
| Q37264185 | Reg4+ deep crypt secretory cells function as epithelial niche for Lgr5+ stem cells in colon |
| Q38996001 | Regulation and plasticity of intestinal stem cells during homeostasis and regeneration |
| Q36898521 | Regulation of stem cell therapies under attack in Europe: for whom the bell tolls |
| Q38797646 | Replacement of Lost Lgr5-Positive Stem Cells through Plasticity of Their Enterocyte-Lineage Daughters |
| Q39518102 | Retinoic acid-induced pancreatic stellate cell quiescence reduces paracrine Wnt-β-catenin signaling to slow tumor progression |
| Q42238141 | Retroviral gene expression control in primary organoid cultures |
| Q42915923 | Robust cre-mediated recombination in small intestinal stem cells utilizing the olfm4 locus |
| Q95601064 | SARS-CoV-2 Productively Infects Human Gut Enterocytes |
| Q112286994 | SARS-CoV-2 infection and replication in human gastric organoids |
| Q94482746 | SARS-CoV-2 productively infects human gut enterocytes |
| Q36322037 | SOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genes |
| Q28586813 | SOX9 is required for the differentiation of paneth cells in the intestinal epithelium |
| Q28507392 | SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production |
| Q21203071 | STRAD pseudokinases regulate axogenesis and LKB1 stability |
| Q51097698 | Selection of personalized patient therapy through the use of knowledge-based computational models that identify tumor-driving signal transduction pathways. |
| Q90090024 | Sequencing metabolically labeled transcripts in single cells reveals mRNA turnover strategies |
| Q52423597 | Sequential cancer mutations in cultured human intestinal stem cells. |
| Q35912854 | Signaling pathways in intestinal development and cancer |
| Q28239639 | Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche |
| Q100761791 | Single-cell derived tumor organoids display diversity in HLA class I peptide presentation |
| Q24628796 | Single-cell dissection of transcriptional heterogeneity in human colon tumors |
| Q34490100 | Single-cell messenger RNA sequencing reveals rare intestinal cell types |
| Q35799683 | Single-molecule transcript counting of stem-cell markers in the mouse intestine |
| Q84616316 | Slide preparation for single-cell-resolution imaging of fluorescent proteins in their three-dimensional near-native environment |
| Q92916829 | Snake Venom Gland Organoids |
| Q57144357 | SnapShot: Growing Organoids from Stem Cells |
| Q63407079 | SnapShot: The Intestinal Crypt |
| Q83155847 | Sox9 marks adult organ progenitors |
| Q40773079 | Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector |
| Q51915523 | Spindle orientation bias in gut epithelial stem cell compartments is lost in precancerous tissue. |
| Q39373980 | Stem Cells in Repair of Gastrointestinal Epithelia |
| Q37905237 | Stem cell self-renewal in intestinal crypt |
| Q38256327 | Stem cell signaling. An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control |
| Q39229334 | Stem cell-derived organoids and their application for medical research and patient treatment |
| Q37769649 | Stem cells and cancer of the stomach and intestine |
| Q38214506 | Stem cells marked by the R-spondin receptor LGR5. |
| Q28294807 | Stem cells, self-renewal, and differentiation in the intestinal epithelium |
| Q37887870 | Strategies for homeostatic stem cell self-renewal in adult tissues |
| Q91238439 | Stratifying infants with cystic fibrosis for disease severity using intestinal organoid swelling as a biomarker of CFTR function |
| Q27685135 | Structure of stem cell growth factor R-spondin 1 in complex with the ectodomain of its receptor LGR5 |
| Q27680931 | Structures of Wnt-Antagonist ZNRF3 and Its Complex with R-Spondin 1 and Implications for Signaling |
| Q91813743 | Studying cellular heterogeneity and drug sensitivity in colorectal cancer using organoid technology |
| Q42478411 | Sumoylation by Ubc9 Regulates the Stem Cell Compartment and Structure and Function of the Intestinal Epithelium in Mice |
| Q46021163 | Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling. |
| Q47322372 | Syndecan-1 promotes Wnt/β-catenin signaling in multiple myeloma by presenting Wnts and R-spondins |
| Q36029963 | T-cell factor 4 (Tcf7l2) maintains proliferative compartments in zebrafish intestine |
| Q47074104 | T-cell factor 4 (tcf7l2) is the main effector of Wnt signaling during zebrafish intestine organogenesis |
| Q34634821 | T-cell factors: turn-ons and turn-offs |
| Q34093875 | TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions |
| Q34122210 | TCF: Lady Justice casting the final verdict on the outcome of Wnt signalling |
| Q39739202 | TGFβ signaling directs serrated adenomas to the mesenchymal colorectal cancer subtype |
| Q93081285 | Tales from the crypt: new insights into intestinal stem cells |
| Q41698268 | Targeting development of incretin-producing cells increases insulin secretion |
| Q36192485 | Targeting mutant RAS in patient-derived colorectal cancer organoids by combinatorial drug screening |
| Q21135289 | The BMP antagonist follistatin-like 1 is required for skeletal and lung organogenesis |
| Q40596602 | The Generation of Organoids for Studying Wnt Signaling |
| Q28512013 | The HMG box transcription factor Sox4 contributes to the development of the endocrine pancreas |
| Q56902573 | The Human Cell Atlas |
| Q46368626 | The Human Cell Atlas |
| Q104450645 | The Human Cell Atlas White Paper |
| Q40167195 | The Intestinal Wnt/TCF Signature. |
| Q34280882 | The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+4' cell markers |
| Q91727724 | The Myofibroblasts' War on Drugs |
| Q106686809 | The Organoid Cell Atlas |
| Q104450592 | The Organoid Cell Atlas: A Rosetta Stone for Biomedical Discovery and Regenerative Therapy |
| Q27021525 | The R-spondin protein family |
| Q37608193 | The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength |
| Q47073676 | The Wnt/beta-catenin pathway regulates cardiac valve formation |
| Q24314491 | The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells |
| Q24623318 | The cytomegalovirus-encoded chemokine receptor US28 promotes intestinal neoplasia in transgenic mice |
| Q28591094 | The ets-domain transcription factor Spdef promotes maturation of goblet and paneth cells in the intestinal epithelium |
| Q35838330 | The gut microbiota keeps enteric glial cells on the move; prospective roles of the gut epithelium and immune system |
| Q24297804 | The inner nuclear membrane protein emerin regulates beta-catenin activity by restricting its accumulation in the nucleus |
| Q37217105 | The intestinal stem cell |
| Q34171959 | The intestinal stem cell signature identifies colorectal cancer stem cells and predicts disease relapse |
| Q24323107 | The kinase TNIK is an essential activator of Wnt target genes |
| Q28476157 | The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/β-catenin coactivators essential for intestinal homeostasis |
| Q53651908 | The rac activator Tiam1 is a Wnt-responsive gene that modifies intestinal tumor development. |
| Q34693980 | The serine-threonine kinase LKB1 is essential for survival under energetic stress in zebrafish |
| Q96816542 | Three-dimensional single-cell imaging for the analysis of RNA and protein expression in intact tumour biopsies |
| Q92060104 | Tissue clonality of dendritic cell subsets and emergency DCpoiesis revealed by multicolor fate mapping of DC progenitors |
| Q92585553 | Tissue-Engineering the Intestine: The Trials before the Trials |
| Q37812949 | Tissue-resident adult stem cell populations of rapidly self-renewing organs |
| Q40555695 | Tissue-specific mutation accumulation in human adult stem cells during life |
| Q34627354 | Tracking adult stem cells. |
| Q48894577 | Tracking down the stem cells of the intestine: strategies to identify adult stem cells |
| Q28507783 | Transcription factor achaete scute-like 2 controls intestinal stem cell fate |
| Q33576343 | Transcription factor achaete-scute homologue 2 initiates follicular T-helper-cell development |
| Q36368585 | Transcription factor target practice |
| Q53325472 | Transcriptome profile of human colorectal adenomas. |
| Q34833389 | Transformation of intestinal stem cells into gastric stem cells on loss of transcription factor Cdx2. |
| Q102059682 | Translation and Replication Dynamics of Single RNA Viruses |
| Q39178351 | Translational applications of adult stem cell-derived organoids. |
| Q47661472 | Troy+ brain stem cells cycle through quiescence and regulate their number by sensing niche occupancy |
| Q47315507 | Troy/TNFRSF19 marks epithelial progenitor cells during mouse kidney development that continue to contribute to turnover in adult kidney |
| Q92129277 | Tubuloids derived from human adult kidney and urine for personalized disease modeling |
| Q24296595 | Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors |
| Q125872316 | Unbiased transcription factor CRISPR screen identifies ZNF800 as master repressor of enteroendocrine differentiation |
| Q28298678 | Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis |
| Q47799650 | Use of CRISPR-modified human stem cell organoids to study the origin of mutational signatures in cancer. |
| Q91948909 | Very Early Onset Inflammatory Bowel Disease: A Clinical Approach With a Focus on the Role of Genetics and Underlying Immune Deficiencies |
| Q52885366 | Visualization of a short-range Wnt gradient in the intestinal stem-cell niche. |
| Q34619783 | WNT signaling and lymphocyte development |
| Q36664354 | WNT signaling in the normal intestine and colorectal cancer |
| Q39154095 | WNT signalling events near the cell membrane and their pharmacological targeting for the treatment of cancer. |
| Q87649649 | What Is Your Conceptual Definition of "Cell Type" in the Context of a Mature Organism? |
| Q21245383 | What does the concept of the stem cell niche really mean today? |
| Q52425658 | Who Is in the Driver's Seat: Tracing Cancer Genes Using CRISPR-Barcoding. |
| Q38307191 | Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer. |
| Q28244920 | Wnt activates the Tak1/Nemo-like kinase pathway |
| Q36144914 | Wnt control of stem cells and differentiation in the intestinal epithelium |
| Q42162259 | Wnt signaling controls the phosphorylation status of beta-catenin. |
| Q36099900 | Wnt signaling in the intestinal epithelium: from endoderm to cancer |
| Q28588683 | Wnt signaling mediates regional specification in the vertebrate face |
| Q44138554 | Wnt signaling regulates expression of the receptor tyrosine kinase met in colorectal cancer |
| Q24337717 | Wnt signaling through inhibition of β-catenin degradation in an intact Axin1 complex |
| Q24646716 | Wnt signaling, lgr5, and stem cells in the intestine and skin |
| Q28593773 | Wnt signalling induces maturation of Paneth cells in intestinal crypts |
| Q28366892 | Wnt signals are transmitted through N-terminally dephosphorylated beta-catenin |
| Q38797398 | Wnt-induced transcriptional activation is exclusively mediated by TCF/LEF. |
| Q27860784 | Wnt/beta-catenin signaling in development and disease |
| Q39346514 | Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities |
| Q26823272 | Wnt/β-catenin signaling and disease |
| Q39319057 | Wnt/β-catenin signaling in adult mammalian epithelial stem cells |
| Q91698737 | Xenograft and organoid model systems in cancer research |
| Q35062431 | You Wnt some, you lose some: oncogenes in the Wnt signaling pathway |
| Q53685195 | ZNRF3 functions in mammalian sex determination by inhibiting canonical WNT signaling. |
| Q35676661 | c-Myb is required for progenitor cell homeostasis in colonic crypts. |
| Q36088890 | p21 loss blocks senescence following Apc loss and provokes tumourigenesis in the renal but not the intestinal epithelium |
| Q57631318 | p53 deletion impairs clearance of chromosomal-instable stem cells in aging telomere-dysfunctional mice |
| Category:Hans Clevers | wikimedia | |
| Arabic (ar / Q13955) | يوهانس كليفرز | wikipedia |
| Egyptian Arabic (arz / Q29919) | هانز كليفرز | wikipedia |
| azb | هانس کولرز | wikipedia |
| Hans Clevers | wikipedia | |
| Hans Clevers | wikipedia | |
| Hans Clevers | wikipedia | |
| ハンス・クレヴァース | wikipedia | |
| Hans Clevers | wikipedia | |
| Hans Clevers | wikipedia | |
| Клеверс, Ханс | wikipedia | |
| Ганс Клеверс | wikipedia |
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