Enormous influence of TNIK knockdown on intracellular signals and cell survival

scientific article published on 28 June 2011

Enormous influence of TNIK knockdown on intracellular signals and cell survival is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/S13577-011-0023-2
P8608Fatcat IDrelease_rxigr7zkgndhzbiz2rm5t5va7i
P698PubMed publication ID21710359

P2093author name stringBaotian Yang
Xiumei Zhou
Jinghua Gui
Jinyun Wu
P2860cites workSignal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCPQ21666110
TNIK, a novel member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and regulates the cytoskeletonQ22010654
The Traf2- and Nck-interacting kinase as a putative effector of Rap2 to regulate actin cytoskeletonQ24302294
The kinase TNIK is an essential activator of Wnt target genesQ24323107
Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APCQ24336321
Adhesion-independent mechanism for suppression of tumor cell invasion by E-cadherinQ24674891
Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanismQ28114789
Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathwayQ28217024
Functional interaction of beta-catenin with the transcription factor LEF-1Q28286884
MINK and TNIK differentially act on Rap2-mediated signal transduction to regulate neuronal structure and AMPA receptor functionQ28578746
Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3beta regulates its stabilityQ28609057
Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complexQ28609062
A Wnt signaling pathway controls hox gene expression and neuroblast migration in C. elegansQ28611337
Traf2- and Nck-interacting kinase is essential for canonical Wnt signaling in Xenopus axis formationQ34074375
The psychiatric disease risk factors DISC1 and TNIK interact to regulate synapse composition and function.Q35223834
Casein kinase I phosphorylates the Armadillo protein and induces its degradation in DrosophilaQ39646951
A Wnt signaling system that specifies two patterns of cell migration in C. elegansQ39749529
The F-box protein beta-TrCP associates with phosphorylated beta-catenin and regulates its activity in the cell.Q40967633
Wnt-1-inducing factor-1: a novel G/C box-binding transcription factor regulating the expression of Wnt-1 during neuroectodermal differentiationQ41569870
Nuclear-cytoplasmic shuttling of APC regulates beta-catenin subcellular localization and turnoverQ42796363
Traf2- and Nck-interacting kinase is essential for Wnt signaling and colorectal cancer growthQ43041589
The C. elegans gene lin-44, which controls the polarity of certain asymmetric cell divisions, encodes a Wnt protein and acts cell nonautonomouslyQ47069049
P433issue3
P304page(s)121-126
P577publication date2011-06-28
P1433published inHuman CellQ26853933
P1476titleEnormous influence of TNIK knockdown on intracellular signals and cell survival
P478volume24

Reverse relations

cites work (P2860)
Q35357838A novel aminothiazole KY-05009 with potential to inhibit Traf2- and Nck-interacting kinase (TNIK) attenuates TGF-β1-mediated epithelial-to-mesenchymal transition in human lung adenocarcinoma A549 cells
Q64072034Characterization of the ERG-regulated Kinome in Prostate Cancer Identifies TNIK as a Potential Therapeutic Target
Q41140196Comprehensive Modeling and Discovery of Mebendazole as a Novel TRAF2- and NCK-interacting Kinase Inhibitor
Q46132376Dynamic change of TNIK in response to tumor necrosis factor alpha in a TRAF2-dependent manner
Q37223261TNIK inhibition abrogates colorectal cancer stemness
Q38600094Targeting the Wnt signaling pathway in colorectal cancer
Q93159737The transcriptional coactivator WBP2 primes triple-negative breast cancer cells for responses to Wnt signaling via the JNK/Jun kinase pathway
Q26778983Therapeutic targets in the Wnt signaling pathway: Feasibility of targeting TNIK in colorectal cancer
Q53142724Traf2- and Nck-interacting kinase (TNIK) is involved in the anti-cancer mechanism of dovitinib in human multiple myeloma IM-9 cells.

Search more.