Gene knockdown studies revealed CCDC50 as a candidate gene in mantle cell lymphoma and chronic lymphocytic leukemia.

scientific article

Gene knockdown studies revealed CCDC50 as a candidate gene in mantle cell lymphoma and chronic lymphocytic leukemia. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/LEU.2009.144
P698PubMed publication ID19641524
P5875ResearchGate publication ID26704278

P50authorMichael BoutrosQ73877448
P2093author name stringE Hartmann
A Pscherer
P Lichter
H Döhner
A Rosenwald
G Ott
S Stilgenbauer
F Engel
M Seiffert
A Farfsing
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Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosisQ24307994
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Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelinesQ24616084
Genomic aberrations and survival in chronic lymphocytic leukemiaQ28141442
Chronic lymphocytic leukemiaQ28236621
Suppression of the ligand-mediated down-regulation of epidermal growth factor receptor by Ymer, a novel tyrosine-phosphorylated and ubiquitinated proteinQ28248770
The metabolism of proline, a stress substrate, modulates carcinogenic pathwaysQ28275923
A20 blocks endothelial cell activation through a NF-kappaB-dependent mechanismQ28282198
Expression profiling reveals off-target gene regulation by RNAiQ29615965
Off-target effects of siRNA specific for GFPQ33346459
In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cellsQ33830733
A20 and A20-binding proteins as cellular inhibitors of nuclear factor-kappa B-dependent gene expression and apoptosisQ34047242
A polymorphic microsatellite that mediates induction of PIG3 by p53.Q34120918
Evidence for distinct pathomechanisms in B-cell chronic lymphocytic leukemia and mantle cell lymphoma by quantitative expression analysis of cell cycle and apoptosis-associated genesQ34130791
Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocationQ34245495
Mutation and genomic deletion status of ataxia telangiectasia mutated (ATM) and p53 confer specific gene expression profiles in mantle cell lymphomaQ34479078
Integrated genomic and expression profiling in mantle cell lymphoma: identification of gene-dosage regulated candidate genes.Q34807976
Mantle cell lymphoma is characterized by inactivation of the ATM geneQ35081325
Specific chromosomal imbalances in human papillomavirus-transfected cells during progression toward immortalityQ36106455
The chromosome 14 breakpoint in neoplastic B cells with the t(11;14) translocation involves the immunoglobulin heavy chain locusQ36264870
Update on the molecular biology of mantle cell lymphomaQ36364527
Specific secondary genetic alterations in mantle cell lymphoma provide prognostic information independent of the gene expression-based proliferation signatureQ36629194
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Molecular diagnostics in chronic lymphocytic leukemia - pathogenetic and clinical implicationsQ37152757
p53 polymorphisms: cancer implicationsQ37376012
Treatment resistance in chronic lymphocytic leukemia: the role of the p53 pathwayQ37434174
Inhibition of NF-kappaB signaling via tyrosine phosphorylation of Ymer.Q39908451
Efficient nucleofection of primary human B cells and B-CLL cells induces apoptosis, which depends on the microenvironment and on the structure of transfected nucleic acidsQ40105838
Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomasQ40234300
Antagonizing inactivated tumor suppressor genes and activated oncogenes by a versatile transgenesis system: application in mantle cell lymphomaQ40288213
Genome-wide array-based CGH for mantle cell lymphoma: identification of homozygous deletions of the proapoptotic gene BIM.Q40479135
Comprehensive whole genome array CGH profiling of mantle cell lymphoma model genomes.Q40540010
Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vectorQ40773079
Inhibition of constitutive NF-kappa B activation in mantle cell lymphoma B cells leads to induction of cell cycle arrest and apoptosisQ44484550
Mantle-cell lymphoma genotypes identified with CGH to BAC microarrays define a leukemic subgroup of disease and predict patient outcomeQ44730863
Cell cycle alterations in the blastoid variant of mantle cell lymphoma (MCL-BV) as detected by gene expression profiling of mantle cell lymphoma (MCL) and MCL-BV.Q46209291
Identification of progression markers in B-CLL by gene expression profilingQ46614433
Designing effective siRNAs with off-target controlQ51582278
Investigatory and analytical approaches to differential gene expression profiling in mantle cell lymphomaQ52026719
A p53-dominant transcriptional response to cisplatin in testicular germ cell tumor-derived human embryonal carcinomaQ53855330
Gene expression profiling of mantle cell lymphoma cells reveals aberrant expression of genes from the PI3K-AKT, WNT and TGFbeta signalling pathways.Q54648964
The proliferation gene expression signature is a quantitative integrator of oncogenic events that predicts survival in mantle cell lymphomaQ57279573
t(11;14)-positive mantle cell lymphomas exhibit complex karyotypes and share similarities with B-cell chronic lymphocytic leukemiaQ73459806
Altered apoptosis pathways in mantle cell lymphoma detected by oligonucleotide microarrayQ74250057
Gain of 3q and deletion of 11q22 are frequent aberrations in mantle cell lymphomaQ74480204
Identification of genes whose expression patterns differ in benign lymphoid tissue and follicular, mantle cell, and small lymphocytic lymphomaQ76312993
Microarray gene expression profiling of B-cell chronic lymphocytic leukemia subgroups defined by genomic aberrations and VH mutation statusQ80809839
Novel chromosomal imbalances in mantle cell lymphoma detected by genome-wide array-based comparative genomic hybridizationQ80894677
Genomic aberrations in mantle cell lymphoma detected by interphase fluorescence in situ hybridization. Incidence and clinicopathological correlationsQ80958713
P433issue11
P921main subjectleukemiaQ29496
mantle cell lymphomaQ268713
lymphocyteQ715347
P304page(s)2018-2026
P577publication date2009-07-30
P1433published inLeukemiaQ6534498
P1476titleGene knockdown studies revealed CCDC50 as a candidate gene in mantle cell lymphoma and chronic lymphocytic leukemia
P478volume23

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cites work (P2860)
Q90362958A Coiled-Coil Domain Containing 50 Splice Variant Is Modulated by Serine/Arginine-Rich Splicing Factor 3 and Promotes Hepatocellular Carcinoma in Mice by the Ras Signaling Pathway
Q96952353A novel selective autophagy receptor, CCDC50, delivers K63 polyubiquitination-activated RIG-I/MDA5 for degradation during viral infection
Q41846273Coiled-coil domain containing 109B is a HIF1α-regulated gene critical for progression of human gliomas
Q104073761Coiled-coil domain containing 50-V2 protein positively regulates neurite outgrowth
Q95660674Combining gene expression profiling and machine learning to diagnose B-cell non-Hodgkin lymphoma
Q39105456Defective DROSHA processing contributes to downregulation of MiR-15/-16 in chronic lymphocytic leukemia
Q30408034Generation of BAC transgenic tadpoles enabling live imaging of motoneurons by using the urotensin II-related peptide (ust2b) gene as a driver
Q45188801Genome-wide scan on total serum IgE levels identifies no common variants in a healthy Chinese male population
Q39229600High expression of crystallin αB represents an independent molecular marker for unfavourable ovarian cancer patient outcome and impairs TRAIL- and cisplatin-induced apoptosis in human ovarian cancer cells.
Q96606076HnRNP A1 - mediated alternative splicing of CCDC50 contributes to cancer progression of clear cell renal cell carcinoma via ZNF395
Q41072852Identification of subtype specific miRNA-mRNA functional regulatory modules in matched miRNA-mRNA expression data: multiple myeloma as a case.
Q48027440Pleomorphic mantle cell lymphoma morphologically mimicking diffuse large B cell lymphoma: common cyclin D1 negativity and a simple immunohistochemical algorithm to avoid the diagnostic pitfall
Q39375022Super-SILAC Allows Classification of Diffuse Large B-cell Lymphoma Subtypes by Their Protein Expression Profiles
Q38315575ZRANB2 localizes to supraspliceosomes and influences the alternative splicing of multiple genes in the transcriptome

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