| scholarly article | Q13442814 |
| P2093 | author name string | Gregory A Cope | |
| Raymond J Deshaies | |||
| P2860 | cites work | The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage | Q24301297 |
| NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases | Q24337709 | ||
| CAND1 binds to unneddylated CUL1 and regulates the formation of SCF ubiquitin E3 ligase complex | Q24337718 | ||
| Pseudosubstrate regulation of the SCF(beta-TrCP) ubiquitin ligase by hnRNP-U | Q24672630 | ||
| Mechanisms underlying ubiquitination | Q27860656 | ||
| Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1. | Q27931858 | ||
| Function and regulation of cullin-RING ubiquitin ligases | Q28131707 | ||
| Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome | Q28187304 | ||
| The COP9 Signalosome Interacts with SCFUFO and Participates in Arabidopsis Flower Development | Q33338332 | ||
| The COP9 signalosome regulates the Neurospora circadian clock by controlling the stability of the SCFFWD-1 complex | Q33891920 | ||
| The SCF(HOS/beta-TRCP)-ROC1 E3 ubiquitin ligase utilizes two distinct domains within CUL1 for substrate targeting and ubiquitin ligation | Q33962019 | ||
| COP9 signalosome: a multifunctional regulator of SCF and other cullin-based ubiquitin ligases | Q35541468 | ||
| A Nedd8 conjugation pathway is essential for proteolytic targeting of p27Kip1 by ubiquitination | Q35687263 | ||
| Human CUL1 forms an evolutionarily conserved ubiquitin ligase complex (SCF) with SKP1 and an F-box protein | Q36490601 | ||
| The COP9 Signalosome Interacts Physically with SCFCOI1 and Modulates Jasmonate Responses | Q38355120 | ||
| NEDD8 recruits E2-ubiquitin to SCF E3 ligase. | Q39731260 | ||
| Cop9/signalosome subunits and Pcu4 regulate ribonucleotide reductase by both checkpoint-dependent and -independent mechanisms | Q39895340 | ||
| Inactivation of hCDC4 can cause chromosomal instability | Q40582502 | ||
| The COP9 signalosome inhibits p27(kip1) degradation and impedes G1-S phase progression via deneddylation of SCF Cul1. | Q40736705 | ||
| Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector | Q40773079 | ||
| Deregulated cyclin E induces chromosome instability | Q41692394 | ||
| COP9 signalosome subunits 4 and 5 regulate multiple pleiotropic pathways in Drosophila melanogaster | Q44132450 | ||
| Conjugation of Nedd8 to CUL1 enhances the ability of the ROC1-CUL1 complex to promote ubiquitin polymerization | Q45345753 | ||
| Drosophila JAB1/CSN5 acts in photoreceptor cells to induce glial cells | Q46188477 | ||
| CSN5/Jab1 mutations affect axis formation in the Drosophila oocyte by activating a meiotic checkpoint | Q46549493 | ||
| The COP9 Signalosome Promotes Degradation of Cyclin E during Early Drosophila Oogenesis | Q46973380 | ||
| The BTB protein MEL-26 is a substrate-specific adaptor of the CUL-3 ubiquitin-ligase. | Q47069071 | ||
| Neddylation and deneddylation of CUL-3 is required to target MEI-1/Katanin for degradation at the meiosis-to-mitosis transition in C. elegans. | Q47069590 | ||
| Neddylation and deneddylation regulate Cul1 and Cul3 protein accumulation. | Q47070899 | ||
| CSN facilitates Cullin-RING ubiquitin ligase function by counteracting autocatalytic adapter instability | Q47845473 | ||
| Fission yeast COP9/signalosome suppresses cullin activity through recruitment of the deubiquitylating enzyme Ubp12p | Q47847570 | ||
| Unified nomenclature for the COP9 signalosome and its subunits: an essential regulator of development | Q48750414 | ||
| Loss of the CONSTITUTIVE PHOTOMORPHOGENIC9 signalosome subunit 5 is sufficient to cause the cop/det/fus mutant phenotype in Arabidopsis. | Q53673743 | ||
| Interactions of the COP9 Signalosome with the E3 Ubiquitin Ligase SCFTIR1 in Mediating Auxin Response | Q58021755 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 1 | |
| P577 | publication date | 2006-01-09 | |
| P1433 | published in | BMC Biochemistry | Q15765786 |
| P1476 | title | Targeted silencing of Jab1/Csn5 in human cells downregulates SCF activity through reduction of F-box protein levels | |
| P478 | volume | 7 |
| Q38666669 | A genome-wide screen identifies p97 as an essential regulator of DNA damage-dependent CDT1 destruction. |
| Q33436063 | Analysis of the role of COP9 Signalosome (CSN) subunits in K562; the first link between CSN and autophagy |
| Q92503635 | Are Inositol Polyphosphates the Missing Link in Dynamic Cullin RING Ligase Regulation by the COP9 Signalosome? |
| Q21284383 | Association of SAP130/SF3b-3 with Cullin-RING ubiquitin ligase complexes and its regulation by the COP9 signalosome |
| Q51957599 | Auxin responses in mutants of the Arabidopsis CONSTITUTIVE PHOTOMORPHOGENIC9 signalosome. |
| Q59284841 | Azaindoles as Zinc-Binding Small-Molecule Inhibitors of the JAMM Protease CSN5 |
| Q48146730 | Azaindoles as Zinc-Binding Small-Molecule Inhibitors of the JAMM Protease CSN5. |
| Q89663750 | Basis for metabolite-dependent Cullin-RING ligase deneddylation by the COP9 signalosome |
| Q34202918 | C. elegans CAND-1 regulates cullin neddylation, cell proliferation and morphogenesis in specific tissues |
| Q40136931 | CAND1 controls in vivo dynamics of the cullin 1-RING ubiquitin ligase repertoire |
| Q37040833 | CDK-mediated activation of the SCF(FBXO) (28) ubiquitin ligase promotes MYC-driven transcription and tumourigenesis and predicts poor survival in breast cancer |
| Q35857063 | CIF-1, a shared subunit of the COP9/signalosome and eukaryotic initiation factor 3 complexes, regulates MEL-26 levels in the Caenorhabditis elegans embryo |
| Q50296662 | COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes |
| Q50296663 | COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex |
| Q57462865 | COP9 signalosome subunit 6 mediates PDGF -induced pulmonary arterial smooth muscle cells proliferation |
| Q53524553 | COP9 signalosome subunit 8 is essential for peripheral T cell homeostasis and antigen receptor-induced entry into the cell cycle from quiescence. |
| Q24293399 | COP9 signalosome subunit Csn8 is involved in maintaining proper duration of the G1 phase |
| Q41790530 | COP9 signalosome- and 26S proteasome-dependent regulation of SCFTIR1 accumulation in Arabidopsis. |
| Q24315611 | COP9-associated CSN5 regulates exosomal protein deubiquitination and sorting |
| Q38015388 | CRL Ubiquitin Ligases and DNA Damage Response |
| Q24298155 | CSN controls NF-kappaB by deubiquitinylation of IkappaBalpha |
| Q47072666 | CSN maintains the germline cellular microenvironment and controls the level of stem cell genes via distinct CRLs in testes of Drosophila melanogaster |
| Q35017567 | CSN-mediated deneddylation differentially modulates Ci(155) proteolysis to promote Hedgehog signalling responses |
| Q37106255 | CSN5 isopeptidase activity links COP9 signalosome activation to breast cancer progression |
| Q31144227 | Characterization of Arabidopsis and rice DWD proteins and their roles as substrate receptors for CUL4-RING E3 ubiquitin ligases |
| Q34785767 | Cullin E3 ligases and their rewiring by viral factors |
| Q21203558 | Cullin-RING ubiquitin ligases: global regulation and activation cycles |
| Q36216079 | Deconjugation of Nedd8 from Cul1 is directly regulated by Skp1-F-box and substrate, and the COP9 signalosome inhibits deneddylated SCF by a noncatalytic mechanism |
| Q33311403 | Downregulation of COP9 signalosome subunits differentially affects the CSN complex and target protein stability |
| Q52602278 | Ethylene-induced stabilization of ETHYLENE INSENSITIVE3 and EIN3-LIKE1 is mediated by proteasomal degradation of EIN3 binding F-box 1 and 2 that requires EIN2 in Arabidopsis. |
| Q42150408 | F-box-directed CRL complex assembly and regulation by the CSN and CAND1 |
| Q36751582 | Genetic analysis of CAND1-CUL1 interactions in Arabidopsis supports a role for CAND1-mediated cycling of the SCFTIR1 complex |
| Q90450495 | Genome-wide screen identifies cullin-RING ligase machinery required for lenalidomide-dependent CRL4CRBN activity |
| Q89519289 | Global site-specific neddylation profiling reveals that NEDDylated cofilin regulates actin dynamics |
| Q50488789 | Immunodepletion and Immunopurification as Approaches for CSN Research. |
| Q24296617 | Impaired DNA damage checkpoint response in MIF-deficient mice |
| Q36020841 | Inhibition of COP9-signalosome (CSN) deneddylating activity and tumor growth of diffuse large B-cell lymphomas by doxycycline |
| Q42425195 | MIF coordinates the cell cycle with DNA damage checkpoints. Lessons from knockout mouse models |
| Q36999094 | Macrophage migration inhibitory factor manipulation and evaluation in tumoral hypoxic adaptation |
| Q42408459 | Modification of Cul1 regulates its association with proteasomal subunits |
| Q38598847 | Murine Myocardial Transcriptome Analysis Reveals a Critical Role of COPS8 in the Gene Expression of Cullin-RING Ligase Substrate Receptors and Redox and Vesicle Trafficking Pathways |
| Q40322425 | Neddylation and CAND1 independently stimulate SCF ubiquitin ligase activity in Candida albicans |
| Q34987403 | Neddylation and deneddylation in cardiac biology |
| Q28483644 | Neurospora COP9 signalosome integrity plays major roles for hyphal growth, conidial development, and circadian function |
| Q42094573 | Novel aspects of COP9 signalosome functions revealed through analysis of hypomorphic csn mutants |
| Q34681633 | Novel mechanism by which histone deacetylase inhibitors facilitate topoisomerase IIα degradation in hepatocellular carcinoma cells |
| Q34474447 | Perturbation of cullin deneddylation via conditional Csn8 ablation impairs the ubiquitin-proteasome system and causes cardiomyocyte necrosis and dilated cardiomyopathy in mice. |
| Q39737412 | Physical interaction of Jab1 with human serotonin 6 G-protein-coupled receptor and their possible roles in cell survival |
| Q48951875 | Potential role of Jun activation domain-binding protein 1 and phosphorylated p27 expression in prognosis of glioma |
| Q39423498 | Prolonged α-amanitin treatment of cells for studying mutated polymerases causes degradation of DSIF160 and other proteins |
| Q34470982 | Recruitment of the inhibitor Cand1 to the cullin substrate adaptor site mediates interaction to the neddylation site |
| Q27686867 | Regulation of abiotic stress signal transduction by E3 ubiquitin ligases in Arabidopsis |
| Q34252986 | Regulation of the Nrf2-Keap1 antioxidant response by the ubiquitin proteasome system: an insight into cullin-ring ubiquitin ligases |
| Q57289570 | Renal COP9 Signalosome Deficiency Alters CUL3-KLHL3-WNK Signaling Pathway |
| Q33769567 | Role of individual subunits of the Neurospora crassa CSN complex in regulation of deneddylation and stability of cullin proteins |
| Q79793647 | Role of the MPN subunits in COP9 signalosome assembly and activity, and their regulatory interaction with Arabidopsis Cullin3-based E3 ligases |
| Q36932100 | Structural and kinetic analysis of the COP9-Signalosome activation and the cullin-RING ubiquitin ligase deneddylation cycle |
| Q89601765 | Structural dynamics of the human COP9 signalosome revealed by cross-linking mass spectrometry and integrative modeling |
| Q36502887 | Targeted inactivation of the COP9 signalosome impairs multiple stages of T cell development |
| Q37364323 | Targeted inhibition of the COP9 signalosome for treatment of cancer |
| Q27652505 | The Arabidopsis COP9 Signalosome Subunit 7 Is a Model PCI Domain Protein with Subdomains Involved in COP9 Signalosome Assembly |
| Q51815311 | The COP9 signalosome counteracts the accumulation of cullin SCF ubiquitin E3 RING ligases during fungal development. |
| Q27931851 | The COP9 signalosome is involved in the regulation of lipid metabolism and of transition metals uptake in Saccharomyces cerevisiae. |
| Q37111543 | The COP9 signalosome is required for light-dependent timeless degradation and Drosophila clock resetting |
| Q37066433 | The COP9 signalosome negatively regulates proteasome proteolytic function and is essential to transcription. |
| Q40237851 | The COP9 signalosome regulates Skp2 levels and proliferation of human cells. |
| Q38292214 | The F-box protein ACRE189/ACIF1 regulates cell death and defense responses activated during pathogen recognition in tobacco and tomato. |
| Q46644321 | The Saccharomyces cerevisiae mitochondrial unselective channel behaves as a physiological uncoupling system regulated by Ca2+, Mg2+, phosphate and ATP. |
| Q24307181 | The glomuvenous malformation protein Glomulin binds Rbx1 and regulates cullin RING ligase-mediated turnover of Fbw7 |
| Q39717057 | The human COP9 signalosome protects ubiquitin-conjugating enzyme 3 (UBC3/Cdc34) from beta-transducin repeat-containing protein (betaTrCP)-mediated degradation |
| Q39686868 | The replication stress response and the ubiquitin system: a new link in maintaining genomic integrity |
| Q46325214 | Thiolutin is a zinc chelator that inhibits the Rpn11 and other JAMM metalloproteases |
| Q36946774 | Ubiquitin ligases in cancer: ushers for degradation |
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