| scholarly article | Q13442814 |
| P50 | author | June-Tai Wu | Q57320915 |
| P2093 | author name string | Cheng-Ting Chien | |
| Hsiu-Chen Lin | |||
| Yen-Chen Hu | |||
| P2860 | cites work | BTB/POZ domain proteins are putative substrate adaptors for cullin 3 ubiquitin ligases | Q79120285 |
| The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage | Q24301297 | ||
| Protein kinase CK2 and protein kinase D are associated with the COP9 signalosome | Q24553124 | ||
| The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2 | Q24597101 | ||
| The fission yeast COP9/signalosome is involved in cullin modification by ubiquitin-related Ned8p | Q24802316 | ||
| Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1. | Q27931858 | ||
| Function and regulation of cullin-RING ubiquitin ligases | Q28131707 | ||
| Covalent modification of all members of human cullin family proteins by NEDD8 | Q28140243 | ||
| Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome | Q28187304 | ||
| The COP9 signalosome: an assembly and maintenance platform for cullin ubiquitin ligases? | Q28188435 | ||
| A hitchhiker's guide to the cullin ubiquitin ligases: SCF and its kin | Q29618006 | ||
| Negative regulation of atonal in proneural cluster formation of Drosophila R8 photoreceptors | Q33860031 | ||
| The COP9 signalosome regulates the Neurospora circadian clock by controlling the stability of the SCFFWD-1 complex | Q33891920 | ||
| Nedd8 on cullin: building an expressway to protein destruction. | Q33976667 | ||
| COP9 signalosome: a multifunctional regulator of SCF and other cullin-based ubiquitin ligases | Q35541468 | ||
| On again – off again: COP9 signalosome turns the key on protein degradation | Q35581416 | ||
| Distinct protein degradation mechanisms mediated by Cul1 and Cul3 controlling Ci stability in Drosophila eye development. | Q35803931 | ||
| NEDD8 recruits E2-ubiquitin to SCF E3 ligase. | Q39731260 | ||
| Conjugation of Nedd8 to CUL1 enhances the ability of the ROC1-CUL1 complex to promote ubiquitin polymerization | Q45345753 | ||
| The COP9 Signalosome Promotes Degradation of Cyclin E during Early Drosophila Oogenesis | Q46973380 | ||
| The BTB protein MEL-26 is a substrate-specific adaptor of the CUL-3 ubiquitin-ligase. | Q47069071 | ||
| Neddylation and deneddylation of CUL-3 is required to target MEI-1/Katanin for degradation at the meiosis-to-mitosis transition in C. elegans. | Q47069590 | ||
| CSN facilitates Cullin-RING ubiquitin ligase function by counteracting autocatalytic adapter instability | Q47845473 | ||
| Fission yeast COP9/signalosome suppresses cullin activity through recruitment of the deubiquitylating enzyme Ubp12p | Q47847570 | ||
| The COP9 Signalosome | Q51111655 | ||
| The Arabidopsis CSN5A and CSN5B subunits are present in distinct COP9 signalosome complexes, and mutations in their JAMM domains exhibit differential dominant negative effects on development. | Q52086696 | ||
| Loss of the CONSTITUTIVE PHOTOMORPHOGENIC9 signalosome subunit 5 is sufficient to cause the cop/det/fus mutant phenotype in Arabidopsis. | Q53673743 | ||
| P433 | issue | 10 | |
| P921 | main subject | protein neddylation | Q21115705 |
| Nedd8 Dmel_CG10679 | Q29815883 | ||
| P304 | page(s) | 1014-1020 | |
| P577 | publication date | 2005-08-28 | |
| P1433 | published in | Nature Cell Biology | Q1574111 |
| P1476 | title | Neddylation and deneddylation regulate Cul1 and Cul3 protein accumulation | |
| P478 | volume | 7 |
| Q36752946 | A Cul-3-BTB ubiquitylation pathway regulates junctional levels and asymmetry of core planar polarity proteins |
| Q34998125 | A Cullin1-based SCF E3 ubiquitin ligase targets the InR/PI3K/TOR pathway to regulate neuronal pruning. |
| Q35745028 | A meta-analysis to evaluate the cellular processes regulated by the interactome of endogenous and over-expressed estrogen receptor alpha. |
| Q38507732 | A new CULLIN 1 mutant has altered responses to hormones and light in Arabidopsis |
| Q30422907 | A quantitative proteomic analysis uncovers the relevance of CUL3 in bladder cancer aggressiveness |
| Q37994645 | A review of the pharmacobiotic regulation of gastrointestinal inflammation by probiotics, commensal bacteria and prebiotics |
| Q33299579 | A ubiquitin ligase complex regulates caspase activation during sperm differentiation in Drosophila |
| Q42674921 | APP-BP1 inhibits Abeta42 levels by interacting with Presenilin-1. |
| Q36291365 | Actin Cytoskeletal Organization in Drosophila Germline Ring Canals Depends on Kelch Function in a Cullin-RING E3 Ligase |
| Q34268301 | Adora2b-elicited Per2 stabilization promotes a HIF-dependent metabolic switch crucial for myocardial adaptation to ischemia |
| Q37289496 | An interaction network of the mammalian COP9 signalosome identifies Dda1 as a core subunit of multiple Cul4-based E3 ligases |
| Q41904906 | Another tier for caspase regulation: IAPs as NEDD8 E3 ligases |
| Q36673300 | Antigen presentation and the ubiquitin-proteasome system in host-pathogen interactions |
| Q41177523 | Breaking the silence: protein stabilization uncovers silenced biosynthetic gene clusters in the fungus Aspergillus nidulans. |
| Q34202918 | C. elegans CAND-1 regulates cullin neddylation, cell proliferation and morphogenesis in specific tissues |
| Q35857063 | CIF-1, a shared subunit of the COP9/signalosome and eukaryotic initiation factor 3 complexes, regulates MEL-26 levels in the Caenorhabditis elegans embryo |
| Q42511084 | COP9 signalosome subunits protect Capicua from MAPK-dependent and -independent mechanisms of degradation |
| Q41790530 | COP9 signalosome- and 26S proteasome-dependent regulation of SCFTIR1 accumulation in Arabidopsis. |
| Q42430485 | COP9-Signalosome deneddylase activity is enhanced by simultaneous neddylation: insights into the regulation of an enzymatic protein complex |
| Q24298155 | CSN controls NF-kappaB by deubiquitinylation of IkappaBalpha |
| Q35017567 | CSN-mediated deneddylation differentially modulates Ci(155) proteolysis to promote Hedgehog signalling responses |
| Q34373827 | CULLIN-3 controls TIMELESS oscillations in the Drosophila circadian clock |
| Q34249169 | Cell type-dependent requirement for PIP box-regulated Cdt1 destruction during S phase |
| Q89072491 | Characterization and comparative expression analysis of CUL1 genes in rice |
| Q31144227 | Characterization of Arabidopsis and rice DWD proteins and their roles as substrate receptors for CUL4-RING E3 ubiquitin ligases |
| Q38302730 | Characterization of the VIER F-BOX PROTEINE genes from Arabidopsis reveals their importance for plant growth and development. |
| Q39794548 | Chemotherapy induces NEDP1-mediated destabilization of MDM2. |
| Q34671745 | Composition, roles, and regulation of cullin-based ubiquitin e3 ligases. |
| Q34585770 | Control of multicellular development by the physically interacting deneddylases DEN1/DenA and COP9 signalosome |
| Q37133559 | Cullin 3 as a novel target in diverse pathologies |
| Q42697295 | Cullin-3 and its adaptor protein ANKFY1 determine the surface level of integrin β1 in endothelial cells |
| Q36328405 | Cullin-3 regulates vascular smooth muscle function and arterial blood pressure via PPARγ and RhoA/Rho-kinase. |
| Q21203558 | Cullin-RING ubiquitin ligases: global regulation and activation cycles |
| Q37629048 | DCUN1D3 activates SCFSKP2 ubiquitin E3 ligase activity and cell cycle progression under UV damage |
| Q33342855 | Deciphering the ubiquitin-mediated pathway in apicomplexan parasites: a potential strategy to interfere with parasite virulence. |
| Q52150059 | Deneddylase 1 regulates deneddylase activity of the Cop9 signalosome in Drosophila melanogaster. |
| Q47070340 | Drosophila Cand1 regulates Cullin3-dependent E3 ligases by affecting the neddylation of Cullin3 and by controlling the stability of Cullin3 and adaptor protein |
| Q89087654 | Dual gain and loss of cullin 3 function mediates familial hyperkalemic hypertension |
| Q42928058 | Epidermal Growth Factor Receptor neddylation is regulated by a desmosomal-COP9 (Constitutive Photomorphogenesis 9) signalosome complex. |
| Q42150408 | F-box-directed CRL complex assembly and regulation by the CSN and CAND1 |
| Q35805066 | Gastrointestinal Tract Commensal Bacteria and Probiotics: Influence on End-Organ Physiology |
| Q34593862 | Genetic screen of a library of chimeric poxviruses identifies an ankyrin repeat protein involved in resistance to the avian type I interferon response. |
| Q33429561 | Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi |
| Q33571373 | Hedgehog signaling downregulates suppressor of fused through the HIB/SPOP-Crn axis in Drosophila |
| Q35905381 | Hypertension-causing Mutations in Cullin3 Protein Impair RhoA Protein Ubiquitination and Augment the Association with Substrate Adaptors. |
| Q24296617 | Impaired DNA damage checkpoint response in MIF-deficient mice |
| Q34023306 | In vivo RNAi screen reveals neddylation genes as novel regulators of Hedgehog signaling |
| Q47174306 | Inhibition of neddylation facilitates cell migration through enhanced phosphorylation of caveolin-1 in PC3 and U373MG cells |
| Q39739721 | Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation |
| Q35036898 | Knockdown of SCF(Skp2) function causes double-parked accumulation in the nucleus and DNA re-replication in Drosophila plasmatocytes |
| Q55006165 | Light Regulates the RUBylation Levels of Individual Cullin Proteins in Arabidopsis thaliana. |
| Q42425195 | MIF coordinates the cell cycle with DNA damage checkpoints. Lessons from knockout mouse models |
| Q60934904 | MLN4924, a Protein Neddylation Inhibitor, Suppresses the Growth of Human Chondrosarcoma through Inhibiting Cell Proliferation and Inducing Endoplasmic Reticulum Stress-Related Apoptosis |
| Q26823231 | Manipulation of fungal development as source of novel secondary metabolites for biotechnology |
| Q52390102 | Mechanisms and controversies in mutant Cul3-mediated Familial Hyperkalemic Hypertension. |
| Q42408459 | Modification of Cul1 regulates its association with proteasomal subunits |
| Q40322425 | Neddylation and CAND1 independently stimulate SCF ubiquitin ligase activity in Candida albicans |
| Q34288710 | Neddylation dysfunction in Alzheimer's disease |
| Q90546259 | Neddylation, a novel paradigm in liver cancer |
| Q28483644 | Neurospora COP9 signalosome integrity plays major roles for hyphal growth, conidial development, and circadian function |
| Q42094573 | Novel aspects of COP9 signalosome functions revealed through analysis of hypomorphic csn mutants |
| Q38992669 | Overactivated neddylation pathway as a therapeutic target in lung cancer. |
| Q35872026 | Prediction of neddylation sites from protein sequences and sequence-derived properties |
| Q37071539 | Proteomics in animal models of Alzheimer's and Parkinson's diseases |
| Q41226375 | Rbf1 degron dysfunction enhances cellular DNA replication |
| Q30413800 | Regulation of parkin and PINK1 by neddylation |
| Q34252986 | Regulation of the Nrf2-Keap1 antioxidant response by the ubiquitin proteasome system: an insight into cullin-ring ubiquitin ligases |
| Q57289570 | Renal COP9 Signalosome Deficiency Alters CUL3-KLHL3-WNK Signaling Pathway |
| Q33769567 | Role of individual subunits of the Neurospora crassa CSN complex in regulation of deneddylation and stability of cullin proteins |
| Q79793647 | Role of the MPN subunits in COP9 signalosome assembly and activity, and their regulatory interaction with Arabidopsis Cullin3-based E3 ligases |
| Q35249854 | Role of the NEDD8 modification of Cul2 in the sequential activation of ECV complex |
| Q36744696 | Squamous Cell Carcinoma-related Oncogene (SCCRO) Family Members Regulate Cell Growth and Proliferation through Their Cooperative and Antagonistic Effects on Cullin Neddylation |
| Q52680513 | Suppression of Hedgehog signaling by Cul3 ligases in proliferation control of retinal precursors. |
| Q37620640 | Suppression of tumor angiogenesis by targeting the protein neddylation pathway |
| Q41147812 | Suppressive role of neddylation in dendritic cells during Mycobacterium tuberculosis infection. |
| Q25256814 | Targeted silencing of Jab1/Csn5 in human cells downregulates SCF activity through reduction of F-box protein levels |
| Q28544912 | The COP9 signalosome converts temporal hormone signaling to spatial restriction on neural competence |
| Q49887000 | The COP9 signalosome inhibits Cullin-RING E3 ubiquitin ligases independently of its deneddylase activity |
| Q37111543 | The COP9 signalosome is required for light-dependent timeless degradation and Drosophila clock resetting |
| Q40237851 | The COP9 signalosome regulates Skp2 levels and proliferation of human cells. |
| Q39990453 | The COP9/signalosome increases the efficiency of von Hippel-Lindau protein ubiquitin ligase-mediated hypoxia-inducible factor-alpha ubiquitination |
| Q28830903 | The E3 ligase Ubr3 regulates Usher syndrome and MYH9 disorder proteins in the auditory organs of Drosophila and mammals |
| Q34202686 | The NEDD8 Conjugation Pathway and Its Relevance in Cancer Biology and Therapy |
| Q37707821 | The SCFSlimb E3 ligase complex regulates asymmetric division to inhibit neuroblast overgrowth. |
| Q34147948 | The emerging role of the COP9 signalosome in cancer |
| Q34770671 | The eta7/csn3-3 auxin response mutant of Arabidopsis defines a novel function for the CSN3 subunit of the COP9 signalosome. |
| Q35148345 | The neddylation-cullin 2-RBX1 E3 ligase axis targets tumor suppressor RhoB for degradation in liver cancer. |
| Q33336573 | The proto-oncogene Int6 is essential for neddylation of Cul1 and Cul3 in Drosophila. |
| Q89768702 | Ubiquitin and ubiquitin-like molecules in DNA double strand break repair |
| Q36022190 | Ubr3, a Novel Modulator of Hh Signaling Affects the Degradation of Costal-2 and Kif7 through Poly-ubiquitination |
| Q34602194 | Uremia and chronic kidney disease: the role of the gut microflora and therapies with pro- and prebiotics |
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