Actin Cytoskeletal Organization in Drosophila Germline Ring Canals Depends on Kelch Function in a Cullin-RING E3 Ligase

scientific article

Actin Cytoskeletal Organization in Drosophila Germline Ring Canals Depends on Kelch Function in a Cullin-RING E3 Ligase is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1534/GENETICS.115.181289
P932PMC publication ID4649639
P698PubMed publication ID26384358

P50authorKatelynn M MannixQ86189940
P2093author name stringAndrew M Hudson
Lynn Cooley
P2860cites workK33-Linked Polyubiquitination of Coronin 7 by Cul3-KLHL20 Ubiquitin E3 Ligase Regulates Protein TraffickingQ24295450
Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signalingQ24298930
Ubiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathwayQ24306215
The Cullin 3 substrate adaptor KLHL20 mediates DAPK ubiquitination to control interferon responsesQ24306576
A Cul3-based E3 ligase removes Aurora B from mitotic chromosomes, regulating mitotic progression and completion of cytokinesis in human cellsQ24307672
Cullin mediates degradation of RhoA through evolutionarily conserved BTB adaptors to control actin cytoskeleton structure and cell movementQ24318748
Regulation of WASH-dependent actin polymerization and protein trafficking by ubiquitinationQ24321352
Adaptor protein self-assembly drives the control of a cullin-RING ubiquitin ligaseQ24336527
The Cul3-KLHL21 E3 ubiquitin ligase targets aurora B to midzone microtubules in anaphase and is required for cytokinesisQ24336860
Sequence and domain organization of scruin, an actin-cross-linking protein in the acrosomal process of Limulus spermQ24672920
Sequence and structural analysis of BTB domain proteinsQ24812693
Building and remodelling Cullin-RING E3 ubiquitin ligasesQ27027816
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin LigasesQ27657740
Structural Basis for Cul3 Protein Assembly with the BTB-Kelch Family of E3 Ubiquitin LigasesQ27675990
Structural and biochemical characterization of the KLHL3–WNK kinase interaction important in blood pressure regulationQ27682289
A proteolytic pathway that recognizes ubiquitin as a degradation signalQ27932607
Sgt1p and Skp1p modulate the assembly and turnover of CBF3 complexes required for proper kinetochore functionQ27935235
Function and regulation of cullin-RING ubiquitin ligasesQ28131707
Regulation of cell polarity and protrusion formation by targeting RhoA for degradationQ28189565
VHL loss causes spindle misorientation and chromosome instability.Q39822734
Looking at oogenesisQ40501183
BTB proteins are substrate-specific adaptors in an SCF-like modular ubiquitin ligase containing CUL-3.Q40633677
Regulating the Yeast Kinetochore by Ubiquitin-Dependent Degradation and Skp1p-Mediated PhosphorylationQ41077870
Gal4 in the Drosophila female germlineQ42465549
The BTB protein MEL-26 promotes cytokinesis in C. elegans by a CUL-3-independent mechanism.Q46708967
The BTB protein MEL-26 is a substrate-specific adaptor of the CUL-3 ubiquitin-ligase.Q47069071
Neddylation and deneddylation regulate Cul1 and Cul3 protein accumulation.Q47070899
Orbit/Mast, the CLASP orthologue of Drosophila, is required for asymmetric stem cell and cystocyte divisions and development of the polarised microtubule network that interconnects oocyte and nurse cells during oogenesis.Q47070935
Importin-alpha 2 is critically required for the assembly of ring canals during Drosophila oogenesisQ47071576
Drosophila filamin encoded by the cheerio locus is a component of ovarian ring canalsQ47072260
The osmolarity of adult Drosophila hemolymph and its effect on oocyte-nurse cell electrical polarityQ49119222
What Determines the Specificity and Outcomes of Ubiquitin Signaling?Q57206327
Short-lived green fluorescent proteins for quantifying ubiquitin/proteasome-dependent proteolysis in living cellsQ61788079
Ubiquitination and degradation of the substrate recognition subunits of SCF ubiquitin-protein ligasesQ77652490
pVHL: a multipurpose adaptor proteinQ81470388
Polyubiquitin chains: polymeric protein signalsQ28294396
A subset of dynamic actin rearrangements in Drosophila requires the Arp2/3 complexQ28756055
Recognition and processing of ubiquitin-protein conjugates by the proteasomeQ29547616
SCF and Cullin/Ring H2-based ubiquitin ligasesQ29547637
Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancerQ29616499
Isolation of mutations in the Drosophila homologues of the human Neurofibromatosis 2 and yeast CDC42 genes using a simple and efficient reverse-genetic method.Q30498647
Drosophila Kelch functions with Cullin-3 to organize the ring canal actin cytoskeletonQ33616443
Methods for studying oogenesisQ33723700
Rotation and asymmetry of the mitotic spindle direct asymmetric cell division in the developing central nervous system.Q33885616
Formation of the Drosophila ovarian ring canal inner rim depends on cheerioQ33969705
kelch encodes a component of intercellular bridges in Drosophila egg chambersQ34061810
A genome-scale shRNA resource for transgenic RNAi in DrosophilaQ34175440
VHL, the story of a tumour suppressor geneQ34455226
Regulation of microtubule stability by the von Hippel-Lindau tumour suppressor protein pVHL.Q34530199
The dominant temperature-sensitive lethal DTS7 of Drosophila melanogaster encodes an altered 20S proteasome beta-type subunit.Q34606007
Construction of transgenic Drosophila by using the site-specific integrase from phage phiC31Q34644225
Crystal structure of KLHL3 in complex with Cullin3Q34661978
Quantitative image analysis identifies pVHL as a key regulator of microtubule dynamic instabilityQ35005618
Phosphoinositide regulation of the actin cytoskeletonQ35019759
The E3 ubiquitin ligase specificity subunit ASB2α targets filamins for proteasomal degradation by interacting with the filamin actin-binding domainQ35112298
The F-box protein Skp2 is a ubiquitylation target of a Cul1-based core ubiquitin ligase complex: evidence for a role of Cul1 in the suppression of Skp2 expression in quiescent fibroblastsQ35116922
Ubiquitin and transcription: The SCF/Met4 pathway, a (protein-) complex issueQ35146031
Ubiquitin-dependent degradation of multiple F-box proteins by an autocatalytic mechanismQ35596995
Control of nonmuscle myosins by phosphorylationQ35671081
Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalitiesQ35754537
Drosophila Kelch Is an Oligomeric Ring Canal Actin OrganizerQ36267663
Filamin is required for ring canal assembly and actin organization during Drosophila oogenesisQ36316648
Drosophila Kelch regulates actin organization via Src64-dependent tyrosine phosphorylationQ36325815
Identification of an essential gene, l(3)73Ai, with a dominant temperature-sensitive lethal allele, encoding a Drosophila proteasome subunitQ36556898
Exploiting position effects and the gypsy retrovirus insulator to engineer precisely expressed transgenesQ36580731
Phylogenetic, structural and functional relationships between WD- and Kelch-repeat proteinsQ37299802
Duplicated proteasome subunit genes in Drosophila and their roles in spermatogenesisQ37412265
Ubiquitination of E3 ligases: self-regulation of the ubiquitin system via proteolytic and non-proteolytic mechanismsQ37849576
Gastrulation: Making and Shaping Germ LayersQ38026928
Signaling mechanisms and functional roles of cofilin phosphorylation and dephosphorylationQ38059941
Stability of homologue of Slimb F-box protein is regulated by availability of its substrateQ38346254
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectcytoskeletonQ154626
DrosophilaQ312154
P1104number of pages15
P304page(s)1117-1131
P577publication date2015-09-16
P1433published inGeneticsQ3100575
P1476titleActin Cytoskeletal Organization in Drosophila Germline Ring Canals Depends on Kelch Function in a Cullin-RING E3 Ligase
P478volume201

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cites work (P2860)
Q44533045A screen for E3 ubiquitination ligases that genetically interact with the adaptor protein Cindr during Drosophila eye patterning
Q38927009Broad-complex, tramtrack, and bric-à-brac (BTB) proteins: Critical regulators of development
Q47284253Cullin 3-Based Ubiquitin Ligases as Master Regulators of Mammalian Cell Differentiation.
Q64970946Cullin-3 dependent deregulation of ACTN1 represents a new pathogenic mechanism in nemaline myopathy.
Q46504619Drosophila glob1 is required for the maintenance of cytoskeletal integrity during oogenesis
Q37151366Oncogenic transformation of Drosophila somatic cells induces a functional piRNA pathway
Q46300798Stay Connected: A Germ Cell Strategy
Q50186703Subcellular Specialization and Organelle Behavior in Germ Cells
Q90595758Targeted substrate degradation by Kelch controls the actin cytoskeleton during ring canal expansion
Q54110383The Misshapen kinase regulates the size and stability of the germline ring canals in the Drosophila egg chamber
Q90118062Transcriptomic and computational analysis identified LPA metabolism, KLHL14 and KCNE3 as novel regulators of Epithelial-Mesenchymal Transition

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