scholarly article | Q13442814 |
P819 | ADS bibcode | 2013PLoSO...860445J |
P356 | DOI | 10.1371/JOURNAL.PONE.0060445 |
P932 | PMC publication ID | 3616122 |
P698 | PubMed publication ID | 23573258 |
P5875 | ResearchGate publication ID | 236189876 |
P2093 | author name string | Gilbert G Privé | |
Alan X Ji | |||
P2860 | cites work | Kelch-like 20 up-regulates the expression of hypoxia-inducible factor-2α through hypoxia- and von Hippel-Lindau tumor suppressor protein-independent regulatory mechanisms. | Q53221890 |
BTB/POZ domain proteins are putative substrate adaptors for cullin 3 ubiquitin ligases | Q79120285 | ||
Crystal structure of the BTB domain from PLZF | Q22003945 | ||
Molecular characterization of KLHL3, a human homologue of the Drosophila kelch gene | Q22254240 | ||
Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex | Q24294734 | ||
Cell surface expression of human ether-a-go-go-related gene (hERG) channels is regulated by caveolin-3 protein via the ubiquitin ligase Nedd4-2 | Q24295274 | ||
Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery | Q24302241 | ||
Nucleoredoxin sustains Wnt/β-catenin signaling by retaining a pool of inactive dishevelled protein | Q24304286 | ||
Ubiquitin-dependent regulation of COPII coat size and function | Q24305964 | ||
KLHL3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron | Q24307394 | ||
Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation | Q24314520 | ||
A Cullin3-KLHL20 Ubiquitin Ligase-Dependent Pathway Targets PML to Potentiate HIF-1 Signaling and Prostate Cancer Progression | Q24322269 | ||
Adaptor protein self-assembly drives the control of a cullin-RING ubiquitin ligase | Q24336527 | ||
Molecular pathogenesis of inherited hypertension with hyperkalemia: the Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4 | Q24541348 | ||
I-TASSER: a unified platform for automated protein structure and function prediction | Q24605680 | ||
A fully automatic evolutionary classification of protein folds: Dali Domain Dictionary version 3 | Q24605760 | ||
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain | Q24609907 | ||
PHENIX: a comprehensive Python-based system for macromolecular structure solution | Q24654617 | ||
Sequence and structural analysis of BTB domain proteins | Q24812693 | ||
Processing of X-ray diffraction data collected in oscillation mode | Q26778468 | ||
Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases | Q27626747 | ||
Structure of a conjugating enzyme-ubiquitin thiolester intermediate reveals a novel role for the ubiquitin tail | Q27635260 | ||
Crystal structure of the BTB domain from the LRF/ZBTB7 transcriptional regulator | Q27640942 | ||
Suprafacial orientation of the SCFCdc4 dimer accommodates multiple geometries for substrate ubiquitination | Q27645983 | ||
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases | Q27657740 | ||
Crystal structure of UbcH5b~ubiquitin intermediate: insight into the formation of the self-assembled E2~Ub conjugates | Q27659805 | ||
Insights into strand exchange in BTB domain dimers from the crystal structures of FAZF and Miz1 | Q27661817 | ||
The molecular basis of CRL4DDB2/CSA ubiquitin ligase architecture, targeting, and activation | Q27675805 | ||
Structural Basis for Cul3 Protein Assembly with the BTB-Kelch Family of E3 Ubiquitin Ligases | Q27675990 | ||
Inference of macromolecular assemblies from crystalline state | Q27860457 | ||
HKL-3000: the integration of data reduction and structure solution--from diffraction images to an initial model in minutes | Q27860502 | ||
Protein structure comparison by alignment of distance matrices | Q27860798 | ||
Features and development of Coot | Q27861079 | ||
Function and regulation of cullin-RING ubiquitin ligases | Q28131707 | ||
Human hypertension caused by mutations in WNK kinases | Q28212182 | ||
The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation | Q28302850 | ||
Toward rational protein crystallization: A Web server for the design of crystallizable protein variants | Q30441331 | ||
Keap1 perceives stress via three sensors for the endogenous signaling molecules nitric oxide, zinc, and alkenals | Q30497261 | ||
Molecular mechanisms of human hypertension | Q32138445 | ||
Kelch-like homologue 9 mutation is associated with an early onset autosomal dominant distal myopathy | Q33944189 | ||
RasGRP1 stimulation enhances ubiquitination and endocytosis of the sodium-chloride cotransporter | Q34085234 | ||
Activity-Dependent Ubiquitination of GluA1 Mediates a Distinct AMPA Receptor Endocytosis and Sorting Pathway | Q34814366 | ||
Modification of keap1 cysteine residues by sulforaphane | Q34909588 | ||
Structural regulation of cullin-RING ubiquitin ligase complexes | Q35151712 | ||
Cullin-based ubiquitin ligases: Cul3-BTB complexes join the family. | Q35740993 | ||
Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities | Q35754537 | ||
K+ channel mutations in adrenal aldosterone-producing adenomas and hereditary hypertension | Q36019674 | ||
Links between dietary salt intake, renal salt handling, blood pressure, and cardiovascular diseases | Q36079020 | ||
Rabex-5 Protein Regulates the Endocytic Trafficking Pathway of Ubiquitinated Neural Cell Adhesion Molecule L1 | Q36294708 | ||
Ubiquitin-dependent sorting of integral membrane proteins for degradation in lysosomes | Q36906047 | ||
Cul3-mediated Nrf2 ubiquitination and antioxidant response element (ARE) activation are dependent on the partial molar volume at position 151 of Keap1. | Q37398830 | ||
A family of LIC vectors for high-throughput cloning and purification of proteins | Q37408286 | ||
Molecular mechanisms of the Keap1–Nrf2 pathway in stress response and cancer evolution | Q37830775 | ||
The cullin protein family | Q37873586 | ||
Smad ubiquitination regulatory factor-2 controls gap junction intercellular communication by modulating endocytosis and degradation of connexin43. | Q39343131 | ||
KLHL12-mediated ubiquitination of the dopamine D4 receptor does not target the receptor for degradation | Q39748131 | ||
BTB proteins are substrate-specific adaptors in an SCF-like modular ubiquitin ligase containing CUL-3. | Q40633677 | ||
ProteinCCD: enabling the design of protein truncation constructs for expression and crystallization experiments | Q43103613 | ||
Identification of sensor cysteines in human Keap1 modified by the cancer chemopreventive agent sulforaphane | Q46854767 | ||
Targeting of protein ubiquitination by BTB–Cullin 3–Roc1 ubiquitin ligases | Q50337002 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 4 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | crystal structure | Q895901 |
P304 | page(s) | e60445 | |
P577 | publication date | 2013-04-03 | |
P1433 | published in | PLOS One | Q564954 |
P1476 | title | Crystal structure of KLHL3 in complex with Cullin3 | |
P478 | volume | 8 |
Q36149053 | A unifying mechanism for WNK kinase regulation of sodium-chloride cotransporter |
Q38742679 | Absolute Amounts and Status of the Nrf2-Keap1-Cul3 Complex within Cells |
Q36291365 | Actin Cytoskeletal Organization in Drosophila Germline Ring Canals Depends on Kelch Function in a Cullin-RING E3 Ligase |
Q38626927 | Association between Cullin-3 Single-Nucleotide Polymorphism rs17479770 and Essential Hypertension in the Male Chinese Han Population |
Q35080292 | Biophysical studies on interactions and assembly of full-size E3 ubiquitin ligase: suppressor of cytokine signaling 2 (SOCS2)-elongin BC-cullin 5-ring box protein 2 (RBX2). |
Q36159459 | Characterisation of the Cullin-3 mutation that causes a severe form of familial hypertension and hyperkalaemia |
Q37133559 | Cullin 3 as a novel target in diverse pathologies |
Q47284253 | Cullin 3-Based Ubiquitin Ligases as Master Regulators of Mammalian Cell Differentiation. |
Q40303257 | Cullin-RING E3 Ubiquitin Ligases: Bridges to Destruction. |
Q47738355 | Decrease of WNK4 ubiquitination by disease-causing mutations of KLHL3 through different molecular mechanisms |
Q88993256 | Decreased KLHL3 expression is involved in the pathogenesis of pseudohypoaldosteronism type II caused by cullin 3 mutation in vivo |
Q36506665 | Generation and analysis of knock-in mice carrying pseudohypoaldosteronism type II-causing mutations in the cullin 3 gene |
Q41728387 | KLHL3 Knockout Mice Reveal the Physiological Role of KLHL3 and the Pathophysiology of Pseudohypoaldosteronism Type II Caused by Mutant KLHL3. |
Q64994328 | KLHL3 single-nucleotide polymorphism is associated with essential hypertension in Chinese Han population. |
Q38916626 | KLHL39 suppresses colon cancer metastasis by blocking KLHL20-mediated PML and DAPK ubiquitination |
Q38920601 | Keap1, the cysteine-based mammalian intracellular sensor for electrophiles and oxidants. |
Q27678830 | Molecular Architecture of the Ankyrin SOCS Box Family of Cul5-Dependent E3 Ubiquitin Ligases |
Q64088977 | Molecular basis of cullin-3 (Cul3) ubiquitin ligase subversion by vaccinia virus protein A55 |
Q41980350 | New strategies to inhibit KEAP1 and the Cul3-based E3 ubiquitin ligases. |
Q38383563 | Revisiting the NaCl cotransporter regulation by with-no-lysine kinases. |
Q27682289 | Structural and biochemical characterization of the KLHL3–WNK kinase interaction important in blood pressure regulation |
Q38522152 | Structural basis of Keap1 interactions with Nrf2. |
Q42694183 | Structural complexity in the KCTD family of Cullin3-dependent E3 ubiquitin ligases |
Q27684072 | Structure of the BTB domain of Keap1 and its interaction with the triterpenoid antagonist CDDO |
Q34043797 | Targeting Cullin-RING E3 ubiquitin ligases for drug discovery: structure, assembly and small-molecule modulation |
Q37237987 | The integrated landscape of driver genomic alterations in glioblastoma |
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