| P2093 | author name string | Chou-Long Huang | |
| | Chih-Jen Cheng | |
| P2860 | cites work | WNK3 kinase is a positive regulator of NKCC2 and NCC, renal cation-Cl- cotransporters required for normal blood pressure homeostasis | Q24294248 |
| | KLHL3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron | Q24307394 |
| | Impaired KLHL3-mediated ubiquitination of WNK4 causes human hypertension | Q24321928 |
| | Kelch-like 3 and Cullin 3 regulate electrolyte homeostasis via ubiquitination and degradation of WNK4 | Q24338315 |
| | Molecular pathogenesis of inherited hypertension with hyperkalemia: the Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4 | Q24541348 |
| | Functional interactions of the SPAK/OSR1 kinases with their upstream activator WNK1 and downstream substrate NKCC1 | Q24548301 |
| | Multiple promoters in the WNK1 gene: one controls expression of a kidney-specific kinase-defective isoform | Q24633475 |
| | WNK1 and OSR1 regulate the Na+, K+, 2Cl- cotransporter in HeLa cells | Q24676697 |
| | Chloride Sensing by WNK1 Involves Inhibition of Autophosphorylation | Q27683663 |
| | WNK kinases, a novel protein kinase subfamily in multi-cellular organisms | Q28188729 |
| | Human hypertension caused by mutations in WNK kinases | Q28212182 |
| | Activation of the thiazide-sensitive Na+-Cl- cotransporter by the WNK-regulated kinases SPAK and OSR1 | Q28268511 |
| | WNK1, a novel mammalian serine/threonine protein kinase lacking the catalytic lysine in subdomain II | Q28581920 |
| | The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases | Q28583124 |
| | WNK kinases regulate thiazide-sensitive Na-Cl cotransport | Q28584824 |
| | A SPAK isoform switch modulates renal salt transport and blood pressure | Q28586855 |
| | Phosphorylation and transport in the Na-K-2Cl cotransporters, NKCC1 and NKCC2A, compared in HEK-293 cells | Q31004742 |
| | Mechanisms of WNK1 and WNK4 interaction in the regulation of thiazide-sensitive NaCl cotransport | Q33736529 |
| | A new methodology for quantification of alternatively spliced exons reveals a highly tissue-specific expression pattern of WNK1 isoforms | Q34305021 |
| | WNK4 is the major WNK positively regulating NCC in the mouse kidney | Q34420520 |
| | SPAK-knockout mice manifest Gitelman syndrome and impaired vasoconstriction | Q34457030 |
| | WNK1 regulates phosphorylation of cation-chloride-coupled cotransporters via the STE20-related kinases, SPAK and OSR1. | Q34464530 |
| | WNK4 kinase regulates surface expression of the human sodium chloride cotransporter in mammalian cells | Q34524228 |
| | The WNKs: atypical protein kinases with pleiotropic actions. | Q34560188 |
| | Crystal structure of KLHL3 in complex with Cullin3 | Q34661978 |
| | SPAK deficiency corrects pseudohypoaldosteronism II caused by WNK4 mutation | Q34988698 |
| | Potassium modulates electrolyte balance and blood pressure through effects on distal cell voltage and chloride | Q35095908 |
| | STE20/SPS1-related proline/alanine-rich kinase (SPAK) is critical for sodium reabsorption in isolated, perfused thick ascending limb | Q35138491 |
| | SPAK/OSR1 regulate NKCC1 and WNK activity: analysis of WNK isoform interactions and activation by T-loop trans-autophosphorylation | Q35623025 |
| | Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities | Q35754537 |
| | Activation of the renal Na+:Cl- cotransporter by angiotensin II is a WNK4-dependent process | Q35974133 |
| | Role of the WNK-activated SPAK kinase in regulating blood pressure | Q36039159 |
| | Familial hyperkalemic hypertension | Q36284783 |
| | A minor role of WNK3 in regulating phosphorylation of renal NKCC2 and NCC co-transporters in vivo | Q36425591 |
| | The thiazide-sensitive Na-Cl cotransporter is an aldosterone-induced protein | Q36738674 |
| | Regulation of NKCC2 by a chloride-sensing mechanism involving the WNK3 and SPAK kinases | Q36751576 |
| | WNK1-related Familial Hyperkalemic Hypertension results from an increased expression of L-WNK1 specifically in the distal nephron | Q37143452 |
| | The emerging family of CULLIN3-RING ubiquitin ligases (CRL3s): cellular functions and disease implications. | Q37163747 |
| | Expression and phosphorylation of the Na+-Cl- cotransporter NCC in vivo is regulated by dietary salt, potassium, and SGK1. | Q37337316 |
| | Regulatory phosphorylation of the secretory Na-K-Cl cotransporter: modulation by cytoplasmic Cl. | Q39196381 |
| | The Effect of WNK4 on the Na+-Cl- Cotransporter Is Modulated by Intracellular Chloride | Q42407751 |
| | Regulation of the NKCC2 ion cotransporter by SPAK-OSR1-dependent and -independent pathways | Q42757015 |
| | WNK1, a Gene within a Novel Blood Pressure Control Pathway, Tissue-Specifically Generates Radically Different Isoforms with and without a Kinase Domain | Q44599907 |
| | WNK-SPAK-NCC cascade revisited: WNK1 stimulates the activity of the Na-Cl cotransporter via SPAK, an effect antagonized by WNK4. | Q48235281 |
| | Isoforms of the Na-K-2Cl cotransporter in murine TAL II. Functional characterization and activation by cAMP. | Q48922687 |
| | Impaired degradation of WNK1 and WNK4 kinases causes PHAII in mutant KLHL3 knock-in mice. | Q53051338 |
| | Potassium and sodium transport along the loop of Henle: Effects of altered dietary potassium intake | Q57717466 |
| | Wnk4 controls blood pressure and potassium homeostasis via regulation of mass and activity of the distal convoluted tubule | Q80238253 |
| | Molecular pathogenesis of pseudohypoaldosteronism type II: generation and analysis of a Wnk4(D561A/+) knockin mouse model | Q80292340 |
| | Rapid dephosphorylation of the renal sodium chloride cotransporter in response to oral potassium intake in mice | Q86215259 |
| P433 | issue | 11 | |
| P304 | page(s) | 2235-2241 | |
| P577 | publication date | 2015-04-24 | |
| P1433 | published in | Pfluegers Archiv | Q1091689 |
| P1476 | title | A unifying mechanism for WNK kinase regulation of sodium-chloride cotransporter | |
| P478 | volume | 467 | |