| scholarly article | Q13442814 |
| P50 | author | Peter Canning | Q58203119 |
| P2093 | author name string | Alex N Bullock | |
| P2860 | cites work | Crystal structure of the BTB domain from PLZF | Q22003945 |
| Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex | Q24294734 | ||
| Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling | Q24298930 | ||
| Ubiquitin-dependent regulation of COPII coat size and function | Q24305964 | ||
| A Cul3-based E3 ligase removes Aurora B from mitotic chromosomes, regulating mitotic progression and completion of cytokinesis in human cells | Q24307672 | ||
| Structure of the Cand1-Cul1-Roc1 complex reveals regulatory mechanisms for the assembly of the multisubunit cullin-dependent ubiquitin ligases | Q24313433 | ||
| Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation | Q24314520 | ||
| Ubiquitin Ligase Activity of Cul3-KLHL7 Protein Is Attenuated by Autosomal Dominant Retinitis Pigmentosa Causative Mutation | Q24320275 | ||
| Impaired KLHL3-Mediated Ubiquitination of WNK4 Causes Human Hypertension | Q24321928 | ||
| A Cullin3-KLHL20 Ubiquitin Ligase-Dependent Pathway Targets PML to Potentiate HIF-1 Signaling and Prostate Cancer Progression | Q24322269 | ||
| Adaptor protein self-assembly drives the control of a cullin-RING ubiquitin ligase | Q24336527 | ||
| The Cul3-KLHL21 E3 ubiquitin ligase targets aurora B to midzone microtubules in anaphase and is required for cytokinesis | Q24336860 | ||
| Kelch-like 3 and Cullin 3 regulate electrolyte homeostasis via ubiquitination and degradation of WNK4 | Q24338315 | ||
| BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase | Q24558689 | ||
| Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2 | Q24563807 | ||
| Cysteine-based regulation of the CUL3 adaptor protein Keap1 | Q24629359 | ||
| BTB Protein KLHL12 targets the dopamine D4 receptor for ubiquitination by a Cul3-based E3 ligase | Q24652896 | ||
| Sequence and structural analysis of BTB domain proteins | Q24812693 | ||
| Different Electrostatic Potentials Define ETGE and DLG Motifs as Hinge and Latch in Oxidative Stress Response | Q27647812 | ||
| Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases | Q27657740 | ||
| Structural Basis for Cul3 Protein Assembly with the BTB-Kelch Family of E3 Ubiquitin Ligases | Q27675990 | ||
| Small molecules inhibit the interaction of Nrf2 and the Keap1 Kelch domain through a non-covalent mechanism | Q27684559 | ||
| Mechanisms underlying ubiquitination | Q27860656 | ||
| Function and regulation of cullin-RING ubiquitin ligases | Q28131707 | ||
| The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation | Q28302850 | ||
| Small Molecule Modulators of Keap1‐Nrf2‐ARE Pathway as Potential Preventive and Therapeutic Agents | Q28386244 | ||
| The gene encoding gigaxonin, a new member of the cytoskeletal BTB/kelch repeat family, is mutated in giant axonal neuropathy | Q28506382 | ||
| Keap1 recruits Neh2 through binding to ETGE and DLG motifs: characterization of the two-site molecular recognition model | Q28910182 | ||
| Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia | Q29614659 | ||
| Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression | Q29615644 | ||
| Keap1 is a forked-stem dimer structure with two large spheres enclosing the intervening, double glycine repeat, and C-terminal domains | Q33734064 | ||
| Kelch-like homologue 9 mutation is associated with an early onset autosomal dominant distal myopathy | Q33944189 | ||
| Discovery of a small-molecule inhibitor and cellular probe of Keap1–Nrf2 protein–protein interaction | Q34657200 | ||
| Crystal structure of KLHL3 in complex with Cullin3 | Q34661978 | ||
| The ubiquitin-proteasome pathway: the complexity and myriad functions of proteins death | Q36184000 | ||
| Mutations in KLHL40 are a frequent cause of severe autosomal-recessive nemaline myopathy | Q37010363 | ||
| Toward clinical application of the Keap1–Nrf2 pathway | Q38105775 | ||
| A small-molecule inducer of the antioxidant response element | Q39695302 | ||
| Will the Ubiquitin System Furnish as Many Drug Targets as Protein Kinases? | Q39812916 | ||
| The CUL3-KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: disease-causing mutations in KLHL3 and WNK4 disrupt interaction | Q39986392 | ||
| Genetic alterations of the NRP/B gene are associated with human brain tumors | Q40543091 | ||
| The CUL3-KLHL18 ligase regulates mitotic entry and ubiquitylates Aurora-A | Q42162215 | ||
| Regulating PLK1 dynamics by Cullin3/KLHL22-mediated ubiquitylation. | Q42790835 | ||
| Peptide inhibitors of the Keap1-Nrf2 protein-protein interaction with improved binding and cellular activity | Q44554497 | ||
| Dimerization of substrate adaptors can facilitate cullin-mediated ubiquitylation of proteins by a "tethering" mechanism: a two-site interaction model for the Nrf2-Keap1 complex | Q53616483 | ||
| P275 | copyright license | Creative Commons Attribution 3.0 Unported | Q14947546 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 1 | |
| P304 | page(s) | 103-107 | |
| P577 | publication date | 2014-02-01 | |
| P1433 | published in | Biochemical Society Transactions | Q864226 |
| P1476 | title | New strategies to inhibit KEAP1 and the Cul3-based E3 ubiquitin ligases | |
| P478 | volume | 42 |
| Q52341567 | AMP-activated protein kinase protects against necroptosis via regulation of Keap1-PGAM5 complex |
| Q36159459 | Characterisation of the Cullin-3 mutation that causes a severe form of familial hypertension and hyperkalaemia |
| Q92178410 | Discovery of a Nitric Oxide-Responsive Protein in Arabidopsis thaliana |
| Q36099459 | Expression profile of a Caenorhabditis elegans model of adult neuronal ceroid lipofuscinosis reveals down regulation of ubiquitin E3 ligase components |
| Q30376217 | High-throughput RNA sequencing reveals structural differences of orthologous brain-expressed genes between western lowland gorillas and humans |
| Q36277241 | Non-electrophilic modulators of the canonical Keap1/Nrf2 pathway |
| Q28077181 | Nrf2 Is an Attractive Therapeutic Target for Retinal Diseases |
| Q61816601 | On the Mechanism of Hyperthermia-Induced BRCA2 Protein Degradation |
| Q47370972 | Organoselenium compounds as mimics of selenoproteins and thiol modifier agents |
| Q27682289 | Structural and biochemical characterization of the KLHL3–WNK kinase interaction important in blood pressure regulation |
| Q38522152 | Structural basis of Keap1 interactions with Nrf2. |
| Q34043797 | Targeting Cullin-RING E3 ubiquitin ligases for drug discovery: structure, assembly and small-molecule modulation |
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