scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1050293306 |
P356 | DOI | 10.1038/SJ.BJC.6605141 |
P932 | PMC publication ID | 2720214 |
P698 | PubMed publication ID | 19536088 |
P5875 | ResearchGate publication ID | 26301044 |
P2093 | author name string | S Napoletano | |
A J Ryan | |||
J H Harmey | |||
P A Fitzpatrick | |||
C A Currid | |||
N C O'Sullivan | |||
P2860 | cites work | The insulin-like growth factor (IGF)-dependent IGF binding protein-4 protease secreted by human fibroblasts is pregnancy-associated plasma protein-A | Q22009032 |
Expression of recombinant human pregnancy-associated plasma protein-A and identification of the proform of eosinophil major basic protein as its physiological inhibitor | Q22254673 | ||
Insulin signalling and the regulation of glucose and lipid metabolism | Q24292020 | ||
Role of tyrosine kinase activity in signal transduction by the insulin-like growth factor-I (IGF-I) receptor. Characterization of kinase-deficient IGF-I receptors and the action of an IGF-I-mimetic antibody (alpha IR-3) | Q24337604 | ||
The role of the acid-labile subunit in regulating insulin-like growth factor transport across human umbilical vein endothelial cell monolayers | Q28260282 | ||
Molecular and cellular aspects of the insulin-like growth factor I receptor | Q28288023 | ||
Insulin-like growth factors and their binding proteins: biological actions | Q28301853 | ||
Pregnancy-associated plasma protein-A (PAPP-A) cleaves insulin-like growth factor binding protein (IGFBP)-5 independent of IGF: implications for the mechanism of IGFBP-4 proteolysis by PAPP-A | Q28616725 | ||
The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited | Q29547915 | ||
Posttranslational regulation of insulin-like growth factor binding protein-4 in normal and transformed human fibroblasts. Insulin-like growth factor dependence and biological studies | Q33893929 | ||
Insulin-like growth factor binding proteins (IGFBPs) as potential physiological substrates for human kallikreins hK2 and hK3. | Q33947270 | ||
Cleavage analysis of insulin-like growth factor (IGF)-dependent IGF-binding protein-4 proteolysis and expression of protease-resistant IGF-binding protein-4 mutants | Q38297936 | ||
IGFBP-4 degradation by pregnancy-associated plasma protein-A in MC3T3 osteoblasts | Q40492882 | ||
Neutralizing anti-insulin-like growth factor receptor 1 antibodies inhibit receptor function and induce receptor degradation in tumor cells. | Q40679071 | ||
Overexpression of an inhibitory insulin-like growth factor binding protein (IGFBP), IGFBP-4, delays onset of prostate tumor formation | Q41021607 | ||
Insulin-like growth factor binding proteins and their role in controlling IGF actions | Q41489957 | ||
Pregnancy-associated plasma protein A: a clinically significant predictor of early recurrence in stage II breast carcinoma | Q41830282 | ||
Regulation of insulin-like growth factor (IGF)-binding protein-4 availability in normal human osteoblast-like cells: role of endogenous IGFs | Q42476933 | ||
Systemic administration of insulin-like growth factor (IGF)-binding protein-4 (IGFBP-4) increases bone formation parameters in mice by increasing IGF bioavailability via an IGFBP-4 protease-dependent mechanism | Q43610678 | ||
Targeted expression of a protease-resistant IGFBP-4 mutant in smooth muscle of transgenic mice results in IGFBP-4 stabilization and smooth muscle hypotrophy | Q43940100 | ||
Lipopolysaccharide-induced metastatic growth is associated with increased angiogenesis, vascular permeability and tumor cell invasion | Q44128389 | ||
Expression of insulin-like growth factor I (IGF-I) gene and of genes for IGF-binding proteins 1, 2, 3, 4 (IGFBP-1-IGFBP-4) in non-neoplastic human thyroid cells and in certain human thyroid cancers. Effect of exogenous IGF-I on this expression. | Q44852228 | ||
Insulin-like growth factor binding protein-4 gene therapy increases apoptosis by altering Bcl-2 and Bax proteins and decreases angiogenesis in colorectal cancer | Q45866411 | ||
Characterization of the enzymatic specificity of the IGF-dependent insulin-like growth factor binding protein-4 (IGFBP-4) protease | Q46046302 | ||
Alphastatin, a 24-amino acid fragment of human fibrinogen, is a potent new inhibitor of activated endothelial cells in vitro and in vivo | Q47602563 | ||
Metalloproteinase pregnancy-associated plasma protein A is a critical growth regulatory factor during fetal development. | Q51028952 | ||
A novel orthotopic model of breast cancer metastasis to bone. | Q52826484 | ||
Protease-resistant insulin-like growth factor (IGF)-binding protein-4 inhibits IGF-I actions and neointimal expansion in a porcine model of neointimal hyperplasia. | Q53539688 | ||
Circulating concentrations of insulin-like growth factor I and risk of breast cancer | Q57751183 | ||
Growth hormone-dependent insulin-like growth factor (IGF) binding protein both inhibits and potentiates IGF-I-stimulated DNA synthesis in human skin fibroblasts | Q70062702 | ||
Plasma insulin-like growth factor-1 (IGF-1) concentrations in human breast cancer | Q70565385 | ||
In vivo inhibition of insulin-like growth factor I gene expression by tamoxifen | Q70646161 | ||
Insulin-like growth factor-binding proteins in R3230AC mammary tumors of intact and diabetic rats | Q72097443 | ||
Insulin-like growth factor binding protein (IGFBP) substrate zymography. A new tool to identify and characterize IGFBP-degrading proteinases | Q74114890 | ||
United Kingdom Co-ordinating Committee on Cancer Research (UKCCCR) Guidelines for the Welfare of Animals in Experimental Neoplasia (Second Edition) | Q74155605 | ||
Modifications of insulin-like growth factor binding proteins and their role in controlling IGF actions | Q77469837 | ||
Models for spontaneous metastasis | Q79182088 | ||
Recombinant human insulin-like growth factor binding protein 3 inhibits growth of human epidermal growth factor receptor-2-overexpressing breast tumors and potentiates herceptin activity in vivo | Q79929885 | ||
Effects of growth-factor combinations on vascular endothelial cell growth in vitro | Q81347761 | ||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | breast cancer | Q128581 |
preproinsulin | Q7240673 | ||
murine model | Q122890741 | ||
P304 | page(s) | 278-286 | |
P577 | publication date | 2009-06-16 | |
P1433 | published in | British Journal of Cancer | Q326309 |
P1476 | title | Expression of a protease-resistant insulin-like growth factor-binding protein-4 inhibits tumour growth in a murine model of breast cancer | |
P478 | volume | 101 |
Q98463541 | Aberrant pregnancy-associated plasma protein-A expression in breast cancers prognosticates clinical outcomes |
Q35998168 | Abnormal IGF-Binding Protein Profile in the Bone Marrow of Multiple Myeloma Patients |
Q34073826 | Control of adipose tissue expandability in response to high fat diet by the insulin-like growth factor-binding protein-4 |
Q33866151 | Estrogen Receptor-β and the Insulin-Like Growth Factor Axis as Potential Therapeutic Targets for Triple-Negative Breast Cancer. |
Q30384833 | Exogenous administration of protease-resistant, non-matrix-binding IGFBP-2 inhibits tumour growth in a murine model of breast cancer. |
Q37620999 | Extracellular matrix signatures of human mammary carcinoma identify novel metastasis promoters |
Q28237971 | IGF binding proteins in cancer: mechanistic and clinical insights |
Q90058359 | IGF-binding proteins 3 and 4 are regulators of sprouting angiogenesis |
Q35836632 | IGFBP ratio confers resistance to IGF targeting and correlates with increased invasion and poor outcome in breast tumors |
Q37207654 | Identification of pregnancy-associated plasma protein A as a migration-promoting gene in malignant pleural mesothelioma cells: a potential therapeutic target |
Q33572235 | Indirect targeting of IGF receptor signaling in vivo by substrate-selective inhibition of PAPP-A proteolytic activity |
Q35693958 | Insulin-like growth factor binding protein-4 differentially inhibits growth factor-induced angiogenesis |
Q30417447 | Insulin-like growth factor binding proteins: a structural perspective |
Q28081603 | Insulin-like growth factor system in cancer: novel targeted therapies |
Q35944697 | Interaction of AIM with insulin-like growth factor-binding protein-4. |
Q35947007 | Key questions and answers about pregnancy-associated plasma protein-A. |
Q30387118 | Multiplex N-terminome analysis of MMP-2 and MMP-9 substrate degradomes by iTRAQ-TAILS quantitative proteomics |
Q42363910 | Overexpression of lncRNA IGFBP4-1 reprograms energy metabolism to promote lung cancer progression |
Q36140682 | Pregnancy associated plasma protein-A links pregnancy and melanoma progression by promoting cellular migration and invasion |
Q57287836 | Pregnancy-Associated Plasma Protein A (PAPP-A) Concentration in Population of Healthy Young People: Interactions with Tobacco Smoke and Anti-oxidative Status |
Q90405825 | Pregnancy-associated plasma protein a in cancer: expression, oncogenic functions and regulation |
Q35019711 | Pregnancy-associated plasma protein-A expression in human breast cancer |
Q38917420 | Preliminary screening of differentially expressed genes involved in methyl-CpG-binding protein 2 gene-mediated proliferation in human osteosarcoma cells |
Q57801325 | Recombinant PAPP-A resistant insulin-like growth factor binding protein 4 (dBP4) inhibits angiogenesis and metastasis in a murine model of breast cancer |
Q34100940 | Relevance of IGFBP2 proteolysis in glioma and contribution of the extracellular protease ADAMTS1 |
Q90447988 | Role of stanniocalcin-1 in breast cancer |
Q27308041 | The Non-coding Mammary Carcinoma Susceptibility Locus, Mcs5c, Regulates Pappa Expression via Age-Specific Chromatin Folding and Allele-Dependent DNA Methylation |
Q35690633 | The role of PAPP-A in the IGF system: location, location, location. |
Q35105295 | The role of the insulin-like growth factor-1 system in breast cancer |
Search more.