| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1051794356 |
| P356 | DOI | 10.1186/S13045-016-0330-X |
| P932 | PMC publication ID | 5039880 |
| P698 | PubMed publication ID | 27678372 |
| P50 | author | Des R. Richardson | Q37369291 |
| Danuta S Kalinowski | Q37840241 | ||
| Zaklina Kovacevic | Q37841084 | ||
| P2093 | author name string | Godfrey Chi-Fung Chan | |
| Kian Cheng Tan-Un | |||
| Zhu-Ling Guo | |||
| P2860 | cites work | Resonance micro-Raman investigations of the rat medial preoptic nucleus: effects of a low-iron diet on the neuroglobin content | Q28583402 |
| MAP kinase signalling pathways in cancer | Q29615542 | ||
| Inhibition of N-myc expression and induction of apoptosis by iron chelation in human neuroblastoma cells. | Q32061432 | ||
| TNF-alpha in cancer treatment: molecular insights, antitumor effects, and clinical utility | Q33239894 | ||
| Regulation and role of neuroglobin and cytoglobin under hypoxia | Q33319494 | ||
| Platelet-derived growth factor enhances platelet recovery in a murine model of radiation-induced thrombocytopenia and reduces apoptosis in megakaryocytes via its receptors and the PI3-k/Akt pathway | Q33390267 | ||
| In vitro and in vivo inhibition of neuroblastoma tumor cell growth by AKT inhibitor perifosine | Q33888833 | ||
| IKK/NF-kappaB signaling: balancing life and death--a new approach to cancer therapy | Q34048503 | ||
| The determination and interpretation of the therapeutic index in drug development | Q34296800 | ||
| The iron chelator Dp44mT inhibits hepatocellular carcinoma metastasis via N-Myc downstream-regulated gene 2 (NDRG2)/gp130/STAT3 pathway | Q34483637 | ||
| Neuroglobin protects neurons against oxidative stress in global ischemia | Q34504972 | ||
| The anticancer agent di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT) overcomes prosurvival autophagy by two mechanisms: persistent induction of autophagosome synthesis and impairment of lysosomal integrity. | Q34580395 | ||
| The expression and localization of N-myc downstream-regulated gene 1 in human trophoblasts | Q34997521 | ||
| Mitogen activated protein (MAP) kinase signal transduction pathways and novel anti-inflammatory targets. | Q35023644 | ||
| Identification of the di-pyridyl ketone isonicotinoyl hydrazone (PKIH) analogues as potent iron chelators and anti-tumour agents | Q35045012 | ||
| A class of iron chelators with a wide spectrum of potent antitumor activity that overcomes resistance to chemotherapeutics | Q35075541 | ||
| Function and evolution of vertebrate globins. | Q35165721 | ||
| Di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT) overcomes multidrug resistance by a novel mechanism involving the hijacking of lysosomal P-glycoprotein (Pgp). | Q35351758 | ||
| Bp44mT: an orally active iron chelator of the thiosemicarbazone class with potent anti-tumour efficacy | Q35657936 | ||
| The proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1. | Q35832242 | ||
| Genetically modified "obligate" anaerobic Salmonella typhimurium as a therapeutic strategy for neuroblastoma. | Q35984126 | ||
| Reversible hexa- to penta-coordination of the heme Fe atom modulates ligand binding properties of neuroglobin and cytoglobin | Q36086240 | ||
| The Metastasis Suppressor, N-MYC Downstream-regulated Gene-1 (NDRG1), Down-regulates the ErbB Family of Receptors to Inhibit Downstream Oncogenic Signaling Pathways | Q36466104 | ||
| New therapeutic strategies in neuroblastoma: combined targeting of a novel tyrosine kinase inhibitor and liposomal siRNAs against ALK. | Q36557133 | ||
| Dp44mT targets the AKT, TGF-β and ERK pathways via the metastasis suppressor NDRG1 in normal prostate epithelial cells and prostate cancer cells. | Q36594041 | ||
| Glucose Modulation Induces Lysosome Formation and Increases Lysosomotropic Drug Sequestration via the P-Glycoprotein Drug Transporter. | Q36594649 | ||
| MYCN gene amplification is a powerful prognostic factor even in infantile neuroblastoma detected by mass screening | Q36614178 | ||
| Novel and potent anti-tumor and anti-metastatic di-2-pyridylketone thiosemicarbazones demonstrate marked differences in pharmacology between the first and second generation lead agents. | Q36618876 | ||
| MYCN-driven regulatory mechanisms controlling LIN28B in neuroblastoma | Q36815139 | ||
| Targeting the Metastasis Suppressor, N-Myc Downstream Regulated Gene-1, with Novel Di-2-Pyridylketone Thiosemicarbazones: Suppression of Tumor Cell Migration and Cell-Collagen Adhesion by Inhibiting Focal Adhesion Kinase/Paxillin Signaling. | Q36852491 | ||
| Cell survival signaling in neuroblastoma | Q37010166 | ||
| Novel chelators for cancer treatment: where are we now? | Q37994291 | ||
| Cellular mechanisms controlling caspase activation and function | Q38111614 | ||
| The complexity of NF-κB signaling in inflammation and cancer | Q38126565 | ||
| Integrative omics reveals MYCN as a global suppressor of cellular signalling and enables network-based therapeutic target discovery in neuroblastoma | Q38294764 | ||
| The renaissance of polypharmacology in the development of anti-cancer therapeutics: Inhibition of the "Triad of Death" in cancer by Di-2-pyridylketone thiosemicarbazones. | Q38576096 | ||
| Effects of chelators (deferoxamine, deferiprone and deferasirox) on the growth of Klebsiella pneumoniae and Aeromonas hydrophila isolated from transfusion-dependent thalassemia patients. | Q38937817 | ||
| The silencing of N-myc downstream-regulated gene-1 in an orthotopic pancreatic cancer model leads to more aggressive tumor growth and metastases. | Q38980659 | ||
| Targeting the metastasis suppressor, NDRG1, using novel iron chelators: regulation of stress fiber-mediated tumor cell migration via modulation of the ROCK1/pMLC2 signaling pathway | Q39236830 | ||
| Novel second-generation di-2-pyridylketone thiosemicarbazones show synergism with standard chemotherapeutics and demonstrate potent activity against lung cancer xenografts after oral and intravenous administration in vivo. | Q39302809 | ||
| The iron-regulated metastasis suppressor NDRG1 targets NEDD4L, PTEN, and SMAD4 and inhibits the PI3K and Ras signaling pathways | Q39371861 | ||
| The iron chelators Dp44mT and DFO inhibit TGF-β-induced epithelial-mesenchymal transition via up-regulation of N-Myc downstream-regulated gene 1 (NDRG1). | Q39372971 | ||
| Mesenchymal stromal cells may enhance metastasis of neuroblastoma via SDF-1/CXCR4 and SDF-1/CXCR7 signaling | Q39476479 | ||
| Antitumor activity of metal-chelating compound Dp44mT is mediated by formation of a redox-active copper complex that accumulates in lysosomes. | Q39508023 | ||
| Novel thiosemicarbazone iron chelators induce up-regulation and phosphorylation of the metastasis suppressor N-myc down-stream regulated gene 1: a new strategy for the treatment of pancreatic cancer | Q39515084 | ||
| The iron chelator Dp44mT causes DNA damage and selective inhibition of topoisomerase IIalpha in breast cancer cells | Q39889950 | ||
| Cytoglobin up-regulated by hydrogen peroxide plays a protective role in oxidative stress | Q40137744 | ||
| Iron chelators with high antiproliferative activity up-regulate the expression of a growth inhibitory and metastasis suppressor gene: a link between iron metabolism and proliferation | Q40536203 | ||
| The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents II: the mechanism of action of ligands derived from salicylaldehyde benzoyl hydrazone and 2-hydroxy-1-naphthylaldehyde benzoyl hydra | Q41115819 | ||
| The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents | Q41268672 | ||
| Targeted activation of human Vγ9Vδ2-T cells controls epstein-barr virus-induced B cell lymphoproliferative disease | Q41739830 | ||
| Cytoglobin, a novel member of the globin family, protects kidney fibroblasts against oxidative stress under ischemic conditions | Q42045242 | ||
| Human neuroglobin functions as an oxidative stress-responsive sensor for neuroprotection | Q42323687 | ||
| N-myc downstream regulated gene 1 modulates Wnt-β-catenin signalling and pleiotropically suppresses metastasis | Q42578068 | ||
| The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents, IV: The mechanisms involved in inhibiting cell-cycle progression | Q43684729 | ||
| Mechanism of antineuroblastoma activity of deferoxamine in vitro. | Q43818220 | ||
| Effects of a single course of deferoxamine in neuroblastoma patients | Q43928023 | ||
| Novel "hybrid" iron chelators derived from aroylhydrazones and thiosemicarbazones demonstrate selective antiproliferative activity against tumor cells | Q44045931 | ||
| Labile plasma iron in iron overload: redox activity and susceptibility to chelation | Q44477026 | ||
| Antibody therapy and neuroblastoma | Q45262456 | ||
| Structure-Activity Relationships of Di-2-pyridylketone, 2-Benzoylpyridine, and 2-Acetylpyridine Thiosemicarbazones for Overcoming Pgp-Mediated Drug Resistance. | Q46501863 | ||
| Lysosomal membrane stability plays a major role in the cytotoxic activity of the anti-proliferative agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT). | Q46560029 | ||
| Novel di-2-pyridyl-derived iron chelators with marked and selective antitumor activity: in vitro and in vivo assessment. | Q47586142 | ||
| The fenton activity of iron(III) in the presence of deferiprone | Q50146798 | ||
| Methemoglobin formation by triapine, di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone (Dp44mT), and other anticancer thiosemicarbazones: identification of novel thiosemicarbazones and therapeutics that prevent this effect. | Q50513017 | ||
| Zinc(II)-Thiosemicarbazone Complexes Are Localized to the Lysosomal Compartment Where They Transmetallate with Copper Ions to Induce Cytotoxicity. | Q53171554 | ||
| Dipyridyl Thiosemicarbazone Chelators with Potent and Selective Antitumor Activity Form Iron Complexes with Redox Activity | Q61050477 | ||
| Deferoxamine, cyclophosphamide, etoposide, carboplatin, and thiotepa (D-CECaT): a new cytoreductive chelation-chemotherapy regimen in patients with advanced neuroblastoma | Q68030510 | ||
| Comparison of activity of deferoxamine with that of oral iron chelators against human neuroblastoma cell lines | Q69609457 | ||
| Antineuroblastoma activity of desferoxamine in human cell lines | Q69745679 | ||
| P433 | issue | 1 | |
| P921 | main subject | neuroblastoma | Q938205 |
| P304 | page(s) | 98 | |
| P577 | publication date | 2016-09-27 | |
| P1433 | published in | Journal of Hematology & Oncology | Q15724593 |
| P1476 | title | The novel thiosemicarbazone, di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone (DpC), inhibits neuroblastoma growth in vitro and in vivo via multiple mechanisms | |
| P478 | volume | 9 |
| Q64121990 | A Novel Synthetic Compound, Bismuth Zinc Citrate, Could Potentially Reduce Cisplatin-Induced Toxicity Without Compromising the Anticancer Effect Through Enhanced Expression of Antioxidant Protein |
| Q92840084 | Advanced glycosylated end products restrain the osteogenic differentiation of the periodontal ligament stem cell |
| Q93200227 | Altered Iron Metabolism and Impact in Cancer Biology, Metastasis, and Immunology |
| Q88646106 | Bafilomycin C1 induces G0/G1 cell-cycle arrest and mitochondrial-mediated apoptosis in human hepatocellular cancer SMMC7721 cells |
| Q38700300 | Di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT), an anticancer agent, exerts an anti-inflammatory effect in activated human mast cells |
| Q50944162 | Interplay of the iron-regulated metastasis suppressor NDRG1 with epidermal growth factor receptor (EGFR) and oncogenic signaling. |
| Q89543584 | Neuroglobin Expression in the Brain: a Story of Tissue Homeostasis Preservation |
| Q99571028 | The Role of Extracellular Proteases in Tumor Progression and the Development of Innovative Metal Ion Chelators that Inhibit their Activity |
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