PECAM-1 is necessary for flow-induced vascular remodeling

scientific article published on 23 April 2009

PECAM-1 is necessary for flow-induced vascular remodeling is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1161/ATVBAHA.109.186692
P932PMC publication ID2723862
P698PubMed publication ID19390054

P2093author name stringZhongming Chen
Ellie Tzima
P2860cites workAxl, a receptor tyrosine kinase, mediates flow-induced vascular remodelingQ28513114
Role of focal adhesion kinase in flow-induced dilation of coronary arteriolesQ28564649
Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodelingQ28592810
Adrenergic catecholamine trophic activity contributes to flow-mediated arterial remodelingQ28593269
Endothelial cell PECAM-1 promotes atherosclerotic lesions in areas of disturbed flow in ApoE-deficient miceQ30439713
Activation of Rac1 by shear stress in endothelial cells mediates both cytoskeletal reorganization and effects on gene expression.Q30453215
Coronary flow velocity and disturbed flow predict adverse clinical outcome after coronary angioplastyQ30842068
Shear stress selectively upregulates intercellular adhesion molecule-1 expression in cultured human vascular endothelial cellsQ34229735
Is PECAM-1 a mechanoresponsive molecule?Q34246895
The relative importance of arterial remodeling compared with intimal hyperplasia in lumen renarrowing after balloon angioplasty. A study in the normal rabbit and the hypercholesterolemic Yucatan micropigQ34342627
Site-specific effects of PECAM-1 on atherosclerosis in LDL receptor-deficient miceQ34455303
Flow-mediated endothelial mechanotransductionQ34648558
Altered vascular permeability and early onset of experimental autoimmune encephalomyelitis in PECAM-1-deficient miceQ34787599
Enhanced susceptibility to endotoxic shock and impaired STAT3 signaling in CD31-deficient miceQ35083590
The NF-kappa B signal transduction pathway in aortic endothelial cells is primed for activation in regions predisposed to atherosclerotic lesion formation.Q35193982
PECAM-1 (CD31) expression modulates bleeding time in vivoQ35745956
Evidence for a role of platelet endothelial cell adhesion molecule-1 in endothelial cell mechanosignal transduction: is it a mechanoresponsive molecule?Q36325631
PECAM-1 is required for transendothelial migration of leukocytesQ36362038
Mechanosensitive production of reactive oxygen species in endothelial and smooth muscle cells: role in microvascular remodeling?Q36566465
Shc coordinates signals from intercellular junctions and integrins to regulate flow-induced inflammationQ36749619
Vascular remodeling: hemodynamic and biochemical mechanisms underlying Glagov's phenomenon.Q36836491
Mechanotransduction in an extracted cell model: Fyn drives stretch- and flow-elicited PECAM-1 phosphorylationQ36843164
PECAM-1: a multi-functional molecule in inflammation and vascular biologyQ36943068
Effect of shear stress on vascular inflammation and plaque development.Q36947987
PECAM-1 functions as a specific and potent inhibitor of mitochondrial-dependent apoptosisQ40662343
The emerging concept of vascular remodelingQ40740827
Endothelial expression of beta1 integrin is required for embryonic vascular patterning and postnatal vascular remodelingQ41911135
Direct evidence for the role of caveolin-1 and caveolae in mechanotransduction and remodeling of blood vesselsQ42825831
Inhibition of transforming growth factor-beta signaling accelerates atherosclerosis and induces an unstable plaque phenotype in mice.Q43794492
Shear stress regulates endothelial nitric oxide synthase expression through c-Src by divergent signaling pathwaysQ43805171
Platelet endothelial cell adhesion molecule deficiency or blockade significantly reduces leukocyte emigration in a majority of mouse strainsQ44239722
Caveolin-1 deficiency stimulates neointima formation during vascular injuryQ44955714
PECAM-1 mediates NO-dependent dilation of arterioles to high temporal gradients of shear stressQ46488035
A mechanosensory complex that mediates the endothelial cell response to fluid shear stressQ46494451
p47phox-dependent NADPH oxidase regulates flow-induced vascular remodelingQ46658437
Role of PECAM-1 in the shear-stress-induced activation of Akt and the endothelial nitric oxide synthase (eNOS) in endothelial cellsQ46665864
Peroxynitrite reduces the endothelium-derived hyperpolarizing factor component of coronary flow-mediated dilation in PECAM-1-knockout miceQ46706026
Prediction of the localization of high-risk coronary atherosclerotic plaques on the basis of low endothelial shear stress: an intravascular ultrasound and histopathology natural history studyQ46771677
Response of vascular endothelial cells to fluid flowQ47843973
Tyrosine phosphorylation of platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) in mechanically stimulated vascular endothelial cellsQ48053148
Impaired carotid and femoral viscoelastic properties and elevated intima-media thickness in peripheral vascular diseaseQ49016204
Altered flow-induced arterial remodeling in vimentin-deficient mice.Q52170187
Crucial role of nuclear factor-kappaB in neointimal hyperplasia of the mouse carotid artery after interruption of blood flow.Q52548975
Injury and repair of endothelium at sites of flow disturbances near abdominal aortic coarctations in rabbits.Q52645517
Shear stress is differentially regulated among inbred rat strainsQ73217723
Shear stress, vascular remodeling and neointimal formationQ73269390
Egr-1 is activated in endothelial cells exposed to fluid shear stress and interacts with a novel shear-stress-response element in the PDGF A-chain promoterQ73832992
Flow-dependent remodeling in the carotid artery of fibroblast growth factor-2 knockout miceQ74461421
Flow-induced vascular remodeling in the mouse: a model for carotid intima-media thickeningQ79202824
Strain-dependent vascular remodeling: the "Glagov phenomenon" is genetically determinedQ80262217
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectmicrovasculature remodelingQ6840464
P304page(s)1067-1073
P577publication date2009-04-23
P1433published inArteriosclerosis, Thrombosis, and Vascular BiologyQ4797542
P1476titlePECAM-1 is necessary for flow-induced vascular remodeling
P478volume29

Reverse relations

cites work (P2860)
Q36917600A novel pathway spatiotemporally activates Rac1 and redox signaling in response to fluid shear stress
Q48310031A novel prospective isolation of murine fetal liver progenitors to study in utero hematopoietic defects.
Q37773118A review of string vessels or collapsed, empty basement membrane tubes
Q30431932Atheroprone hemodynamics regulate fibronectin deposition to create positive feedback that sustains endothelial inflammation
Q28391498Biomechanical regulation of vascular smooth muscle cell functions: from in vitro to in vivo understanding
Q28067208Biomechanics of vascular mechanosensation and remodeling
Q37419996Blood pressure regulation VIII: resistance vessel tone and implications for a pro-atherogenic conduit artery endothelial cell phenotype
Q33402947Coronary artery remodeling in a model of left ventricular pressure overload is influenced by platelets and inflammatory cells
Q92631077Differential Expression of CD31 and Von Willebrand Factor on Endothelial Cells in Different Regions of the Human Brain: Potential Implications for Cerebral Malaria Pathogenesis
Q38888511Endothelial Mechanosignaling: Does One Sensor Fit All?
Q55334826Endothelial Mechanotransduction, Redox Signaling and the Regulation of Vascular Inflammatory Pathways.
Q37570842Endothelial Shc regulates arteriogenesis through dual control of arterial specification and inflammation via the notch and nuclear factor-κ-light-chain-enhancer of activated B-cell pathways
Q37692624Endothelial damage and stem cell repair in atherosclerosis
Q38630594Endothelial fluid shear stress sensing in vascular health and disease.
Q52682483Epidermal growth factor receptor and integrins control force-dependent vinculin recruitment to E-cadherin junctions.
Q36224920Fasudil, a Rho‑kinase inhibitor, prevents intima‑media thickening in a partially ligated carotid artery mouse model: Effects of fasudil in flow‑induced vascular remodeling
Q44405673Fluid upstream shear stress of rabbit aortic stenosis inhibits neointimal hyperplasia by promoting endothelization after balloon injury.
Q37605148Haemodynamics Regulate Fibronectin Assembly via PECAM.
Q35132388Heterogeneity in vascular smooth muscle cell embryonic origin in relation to adult structure, physiology, and disease
Q26740033High shear stress induces atherosclerotic vulnerable plaque formation through angiogenesis
Q30411892Human haemodynamic frequency harmonics regulate the inflammatory phenotype of vascular endothelial cells
Q35671749Induction and functional significance of the heme oxygenase system in pathological shear stress in vivo
Q35287043Inhibition of c-Jun N-terminal kinase attenuates low shear stress-induced atherogenesis in apolipoprotein E-deficient mice
Q34283441Interaction of platelet endothelial cell adhesion molecule (PECAM) with α2,6-sialylated glycan regulates its cell surface residency and anti-apoptotic role
Q91999309Interscapular and Perivascular Brown Adipose Tissue Respond Differently to a Short-Term High-Fat Diet
Q37722078Live cell imaging of mechanotransduction
Q30359910Local VE-cadherin mechanotransduction triggers long-ranged remodeling of endothelial monolayers.
Q35749601Mechanosignaling in the vasculature: emerging concepts in sensing, transduction and physiological responses
Q38022553Mechanotransduction in embryonic vascular development.
Q38170412Mechanotransduction in the endothelium: role of membrane proteins and reactive oxygen species in sensing, transduction, and transmission of the signal with altered blood flow
Q33761538Modeling of shear stress experienced by endothelial cells cultured on microstructured polymer substrates in a parallel plate flow chamber
Q56450693Modulation of functional responses of endothelial cells linked to angiogenesis and inflammation by shear stress: Differential effects of the mechanotransducer CD31
Q38125279Molecular biology of atherosclerosis
Q54373480Nitric oxide modulates lipopolysaccharide-induced endothelial platelet endothelial cell adhesion molecule expression via interleukin-10.
Q33796288PDGF-BB and TGF-{beta}1 on cross-talk between endothelial and smooth muscle cells in vascular remodeling induced by low shear stress
Q64071660PECAM-1 Stabilizes Blood-Brain Barrier Integrity and Favors Paracellular T-Cell Diapedesis Across the Blood-Brain Barrier During Neuroinflammation
Q36473318PECAM-1 isoforms, eNOS and endoglin axis in regulation of angiogenesis
Q34049296PECAM-1: conflicts of interest in inflammation
Q36494937PECAM1 regulates flow-mediated Gab1 tyrosine phosphorylation and signaling
Q45972266Platelet Endothelial Cell Adhesion Molecule-1 and Oligodendrogenesis: Significance in Alcohol Use Disorders.
Q35088053Platelet endothelial cell adhesion molecule-1 mediates endothelial-cardiomyocyte communication and regulates cardiac function.
Q34586633Platelet-endothelial cell adhesion molecule-1 regulates endothelial NO synthase activity and localization through signal transducers and activators of transcription 3-dependent NOSTRIN expression
Q35595505Rap1 promotes endothelial mechanosensing complex formation, NO release and normal endothelial function.
Q57027553Role of Extracellular Matrix in Development and Cancer Progression
Q35630546Role of PECAM-1 in Arteriogenesis and Specification of Preexisting Collaterals
Q35905282Structural Determinants of the Mechanical Stability of α-Catenin
Q34082971The effects of hemodynamic force on embryonic development
Q26770162The force within: endocardial development, mechanotransduction and signalling during cardiac morphogenesis
Q50543643The roadmap of WT1 protein expression in the human fetal heart.
Q39115261Vascular Adaptation to Exercise in Humans: Role of Hemodynamic Stimuli

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