Shear stress selectively upregulates intercellular adhesion molecule-1 expression in cultured human vascular endothelial cells

scientific article

Shear stress selectively upregulates intercellular adhesion molecule-1 expression in cultured human vascular endothelial cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1172/JCI117410
P932PMC publication ID296171
P698PubMed publication ID7518844

P2093author name stringC F Dewey
M A Gimbrone
W J Atkinson
T Nagel
N Resnick
P2860cites workDirect expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytesQ24339405
SelectinsQ24602099
Integrins: versatility, modulation, and signaling in cell adhesionQ27860844
Adhesion receptors of the immune systemQ29616393
Fluid shear stress differentially modulates expression of genes encoding basic fibroblast growth factor and platelet-derived growth factor B chain in vascular endotheliumQ33905997
Mechanotransduction Across the Cell Surface and Through the CytoskeletonQ34306171
Regulation of genetic expression in shear stress-stimulated endothelial cellsQ35446683
Turbulent fluid shear stress induces vascular endothelial cell turnover in vitroQ35597409
Vascular fluid mechanics, the arterial wall, and atherosclerosisQ35822929
Functional analysis of the human vascular cell adhesion molecule 1 promoterQ36232054
Platelet-derived growth factor B chain promoter contains a cis-acting fluid shear-stress-responsive element.Q36306770
Regulation of endothelin 1 gene by fluid shear stress is transcriptionally mediated and independent of protein kinase C and cAMP.Q36388240
Culture of vascular endotheliumQ37051954
The role of endothelial cells in inflammationQ37970834
Endothelial dysfunction and atherosclerosisQ38246984
An NF kappa B-like factor is essential but not sufficient for cytokine induction of endothelial leukocyte adhesion molecule 1 (ELAM-1) gene transcriptionQ40503880
Mechanical stress mechanisms and the cell. An endothelial paradigmQ40868429
Endothelial nuclear factor-kappa B and the initiation of the atherosclerotic lesionQ40909179
Cloning and characterization of the 5'-transcriptional regulatory region of the human intercellular adhesion molecule 1 geneQ42464518
Pulsatile and steady flow induces c-fos expression in human endothelial cellsQ42509401
Overlapping patterns of activation of human endothelial cells by interleukin 1, tumor necrosis factor, and immune interferonQ42511354
The requirement for lymphocyte function-associated antigen 1 in homotypic leukocyte adhesion stimulated by phorbol esterQ42938027
Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesisQ44121998
Shear stress increases endothelial platelet-derived growth factor mRNA levelsQ44918327
The Effect of Flow on the Expression of Vascular Adhesion Molecule-1 by Cultured Mouse Endothelial CellsQ54740883
Vascular endothelium responds to fluid shear stress gradientsQ67570891
Physiological fluid shear stress causes downregulation of endothelin-1 mRNA in bovine aortic endotheliumQ68030565
The Dynamic Response of Vascular Endothelial Cells to Fluid Shear StressQ70917222
Application of Heated-Film Velocity and Shear Probes to Hemodynamic StudiesQ72232464
Endothelial expression of thrombomodulin is reversibly regulated by fluid shear stressQ72360213
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectendotheliumQ111140
P304page(s)885-891
P577publication date1994-08-01
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleShear stress selectively upregulates intercellular adhesion molecule-1 expression in cultured human vascular endothelial cells
P478volume94

Reverse relations

cites work (P2860)
Q35770072A comparison of stent-induced stenosis in coronary and peripheral arteries
Q42141906A microfluidic membrane device to mimic critical components of the vascular microenvironment
Q24309485A mitogenic action for fibrinogen mediated through intercellular adhesion molecule-1
Q44149000A new dynamic in vitro model for the multidimensional study of astrocyte-endothelial cell interactions at the blood-brain barrier
Q33719370A spatial approach to transcriptional profiling: mechanotransduction and the focal origin of atherosclerosis
Q30453215Activation of Rac1 by shear stress in endothelial cells mediates both cytoskeletal reorganization and effects on gene expression.
Q46270359Allopurinol protects human glomerular endothelial cells from high glucose-induced reactive oxygen species generation, p53 overexpression and endothelial dysfunction.
Q47224745Alternative RNA splicing in the endothelium mediated in part by Rbfox2 regulates the arterial response to low flow
Q44451394An intravital model to monitor steps of metastatic tumor cell adhesion within the hepatic microcirculation
Q51798668Analysis of the effect of disturbed flow on monocytic adhesion to endothelial cells
Q30538407Arterial embolism caused by large mobile aortic thrombus in the absence of atherosclerosis, associated with iron deficiency anemia
Q38730458Assembly and reorientation of stress fibers drives morphological changes to endothelial cells exposed to shear stress.
Q37450201Association of HIV viral load with monocyte chemoattractant protein-1 and atherosclerosis burden measured by magnetic resonance imaging
Q78023007Atherosclerosis and inflammation mononuclear cell recruitment and adhesion molecules with reference to the implication of ICAM-1/LFA-1 pathway in atherogenesis
Q33876515Autoimmunity and vascular involvement in systemic sclerosis (SSc).
Q44070275Beraprost sodium, prostacyclin analogue, attenuates glomerular hyperfiltration and glomerular macrophage infiltration by modulating ecNOS expression in diabetic rats
Q35808632Beyond cholesterol--inflammatory cytokines, the key mediators in atherosclerosis
Q37365799Biomechanical activation: an emerging paradigm in endothelial adhesion biology
Q33544042Blood flow and vascular gene expression: fluid shear stress as a modulator of endothelial phenotype
Q36224629Blood flow modulation of vascular dynamics.
Q33843636C-reactive protein, inflammation, and coronary risk
Q79299389C-reactive protein, inflammation, and coronary risk
Q33686005Cellular adhesion molecules and atherogenesis
Q33396892Cellular and molecular mechanism regulating blood flow recovery in acute versus gradual femoral artery occlusion are distinct in the mouse
Q38103602Cellular and pharmacological targets to induce coronary arteriogenesis
Q35106977Cellular mechanics and gene expression in blood vessels
Q33772440Chemokines and atherosclerosis
Q42367553Chronic administration of mitochondrion-targeted peptide SS-31 prevents atherosclerotic development in ApoE knockout mice fed Western diet
Q64381708Chronic in vitro shear stress stimulates endothelial cell retention on prosthetic vascular grafts and reduces subsequent in vivo neointimal thickness
Q34561325Chronic venous insufficiency and the therapeutic effects of Daflon 500 mg.
Q39785458Circumferential deformation and shear stress induce differential responses in saphenous vein endothelium exposed to arterial flow
Q36602479Coexisting proinflammatory and antioxidative endothelial transcription profiles in a disturbed flow region of the adult porcine aorta.
Q35378416Comparative endothelial cell response on topographically patterned titanium and silicon substrates with micrometer to sub-micrometer feature sizes
Q33575988Correlation between the levels of circulating adhesion molecules and atherosclerosis in type-2 diabetic normotensive patients: circulating adhesion molecules and atherosclerosis
Q46528248Cyclic mechanical stretch induces VEGF and FGF-2 expression in pulmonary vascular smooth muscle cells
Q77975393Cyclic-strain-induced endothelial cell expression of adhesion molecules and their roles in monocyte-endothelial interaction
Q39425813Cyclosporine enhances leukocyte adhesion to vascular endothelium under physiologic flow conditions
Q33929217DNA microarray reveals changes in gene expression of shear stressed human umbilical vein endothelial cells
Q64018871DNA microarray study on gene expression profiles in co-cultured endothelial and smooth muscle cells in response to 4- and 24-h shear stress
Q42039182Decreased blood flow rate disrupts endothelial repair in vivo
Q46107491Decreased surfactant proteins in lambs with pulmonary hypertension secondary to increased blood flow
Q56891620Development of an in vitro model to study the response of saphenous vein endothelium to pulsatile arterial flow and circumferential deformation
Q42528763Differential effect of shear stress on extracellular signal-regulated kinase and N-terminal Jun kinase in endothelial cells. Gi2- and Gbeta/gamma-dependent signaling pathways
Q35832018Differentiation and Distribution of Marrow Stem Cells in Flex-Flow Environments Demonstrate Support of the Valvular Phenotype
Q35049081Differing mechanisms of leukocyte recruitment and sensitivity to conditioning by shear stress for endothelial cells treated with tumour necrosis factor-alpha or interleukin-1beta
Q33849349Distinct roles for the small GTPases Cdc42 and Rho in endothelial responses to shear stress
Q79117080Divergent effects of GM‐CSF and TGFβ1on bone marrow‐ derived macrophage arginase‐1 activity, MCP‐1 expression, and matrix‐metalloproteinase‐12: a potential role during arteriogenesis
Q48282416Divergent endothelial function but similar platelet microvesicle responses following eccentric and concentric cycling at a similar aerobic power output.
Q73846801Effect of retroviral transduction on human endothelial cell phenotype and adhesion to Dacron vascular grafts
Q44006946Effect of shear stress on migration and integrin expression in macaque trophoblast cells
Q42458736Effects of AT1 receptor antagonist losartan on sICAM-1 and TNF-alpha levels in uncomplicated hypertensive patients
Q37137604Effects of Swedish massage therapy on blood pressure, heart rate, and inflammatory markers in hypertensive women
Q34107251Effects of diet and of dietary components on endothelial leukocyte adhesion molecules
Q40421153Elucidation of the role of plaque instability and rupture in acute coronary events
Q38108841Emerging understanding of roles for arterioles in inflammation
Q57445695Endothelial Cell ICAM-1 Staining in Human Carotid Arteries
Q37280276Endothelial heterogeneity associated with regional athero-susceptibility and adaptation to disturbed blood flow in vivo
Q34670556Endothelial protein kinase C isoform identity and differential activity of PKCzeta in an athero-susceptible region of porcine aorta
Q36198419Endothelialization of small-diameter vascular prostheses
Q39806745Enhanced expression of heat shock protein 70 (hsp70) and heat shock factor 1 (HSF1) activation in rheumatoid arthritis synovial tissue. Differential regulation of hsp70 expression and hsf1 activation in synovial fibroblasts by proinflammatory cytoki
Q35798412Enhanced expression of intracellular adhesion molecule-1 and P-selectin in the diabetic human retina and choroid.
Q44429133Epinephrine promotes pulmonary angiitis: evidence for a β1-adrenoreceptor-mediated mechanism
Q43901229Estradiol down-regulates MCP-1 expression in human coronary artery endothelial cells
Q47910445Expression of vascular adhesion molecules in saphenous vein coronary bypass grafts
Q28261711Flow-Dependent Epigenetic DNA Methylation in Endothelial Gene Expression and Atherosclerosis
Q28482807Flow-dependent mass transfer may trigger endothelial signaling cascades
Q73676316Flow-induced arterial enlargement is inhibited by suppression of nitric oxide synthase activity in vivo
Q34648558Flow-mediated endothelial mechanotransduction
Q34414377Fluid Mechanics, Arterial Disease, and Gene Expression
Q39805402Fluid shear stress activation of egr-1 transcription in cultured human endothelial and epithelial cells is mediated via the extracellular signal-related kinase 1/2 mitogen-activated protein kinase pathway
Q33788648Fluid shear stress as a regulator of gene expression in vascular cells: possible correlations with diabetic abnormalities
Q74255870Gene expression of inflammatory mediators in different chambers of the human heart
Q48616351Genomic analysis of immediate/early response to shear stress in human coronary artery endothelial cells
Q36210221Glycocalyx Degradation Induces a Proinflammatory Phenotype and Increased Leukocyte Adhesion in Cultured Endothelial Cells under Flow
Q37796322Hemodynamic forces in endothelial dysfunction and vascular aging
Q71331971Hemodynamic modulation of monocytic cell adherence to vascular endothelium
Q78256782Identification of stretch-responsive genes in pulmonary artery smooth muscle cells by a two arbitrary primer-based mRNA differential display approach
Q37341184Identification of vascular endothelial genes differentially responsive to fluid mechanical stimuli: cyclooxygenase-2, manganese superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear str
Q31122079Impact of Hemoglobin Levels and Anemia on Mortality in Acute Stroke: Analysis of UK Regional Registry Data, Systematic Review, and Meta-Analysis
Q64054924Impact of combined plaque structural stress and wall shear stress on coronary plaque progression, regression, and changes in composition
Q35627752In vitro recapitulation of functional microvessels for the study of endothelial shear response, nitric oxide and [Ca2+]i
Q48027890In vivo assessment of angioarchitecture and microcirculation in experimental liver cancer: a new model in rats
Q42126892In vivo imaging of endothelial cell adhesion molecule expression after radiosurgery in an animal model of arteriovenous malformation.
Q34735484In vivo nanoparticle assessment of pathological endothelium predicts the development of inflow stenosis in murine arteriovenous fistula
Q46022159Increased pulmonary blood flow does not alter surfactant protein gene expression in lambs within the first week of life.
Q41730620Influence of stenosis morphology on flow through severely stenotic vessels: implications for plaque rupture
Q37071944Inhibition of endothelial nitric oxide synthase decreases breast cancer cell MDA-MB-231 adhesion to intact microvessels under physiological flows
Q41287170Inhibitors of endothelin
Q27324561Inhibitory Effect of Serotonin Antagonist on Leukocyte-Endothelial Interactions In Vivo and In Vitro
Q37634928Interaction between integrin α5 and PDE4D regulates endothelial inflammatory signalling
Q44599812Intercellular Adhesion Molecule-1–Deficient Mice Are Resistant Against Renal Injury After Induction of Diabetes
Q58366450Intercellular adhesion molecule-1 plays a critical role in glomerulosclerosis after subtotal nephrectomy
Q40957917Intercellular adhesion molecule-1.
Q50438378Kruppel-like factors in an endothelial and vascular smooth muscle cell coculture model: impact of a diabetic environment and vitamin D.
Q44172121Laminar flow induction of antioxidant response element-mediated genes in endothelial cells. A novel anti-inflammatory mechanism
Q33746665Leukocyte adhesion molecules in atherogenesis
Q77584938Leukocyte-endothelium adhesion molecules in atherosclerosis
Q34873268Local delivery of polarized macrophages improves reperfusion recovery in a mouse hind limb ischemia model
Q30432582Matrix-specific protein kinase A signaling regulates p21-activated kinase activation by flow in endothelial cells
Q46066067Mechanical strain increases expression of the brain natriuretic peptide gene in rat cardiac myocytes
Q73268508Mechanical stretching induces interleukin-8 gene expression in fetal membranes: a possible role for the initiation of human parturition
Q30278752Mechanisms of Amplified Arteriogenesis in Collateral Artery Segments Exposed to Reversed Flow Direction
Q44118160Mechanisms of endothelial survival under shear stress.
Q49191713MicroRNA-146a Regulates Perfusion Recovery in Response to Arterial Occlusion via Arteriogenesis
Q54614366Microarray analysis of a reversible model and an irreversible model of anti-Thy-1 nephritis.
Q37580782Microvesicles Derived from Inflammation-Challenged Endothelial Cells Modulate Vascular Smooth Muscle Cell Functions
Q41715190Molecular biology of atherosclerosis
Q37421757Molecular mechanisms responsible for the atheroprotective effects of laminar shear stress.
Q37296292Monocyte transplantation for neural and cardiovascular ischemia repair
Q35753478Mouse model of venous bypass graft arteriosclerosis
Q44323109NOS inhibition accelerates atherogenesis: reversal by exercise
Q35589747Neutrophils and leucocyte adhesion molecules in sickle cell retinopathy
Q36273957Novel cytokine-independent induction of endothelial adhesion molecules regulated by platelet/endothelial cell adhesion molecule (CD31).
Q35753630Nuclear factor-kappa B interacts functionally with the platelet-derived growth factor B-chain shear-stress response element in vascular endothelial cells exposed to fluid shear stress.
Q43900719Numerical analysis of flow through a severely stenotic carotid artery bifurcation
Q38876119Omics-based approaches to understand mechanosensitive endothelial biology and atherosclerosis
Q36375890P-Selectin or intercellular adhesion molecule (ICAM)-1 deficiency substantially protects against atherosclerosis in apolipoprotein E-deficient mice
Q37297380PECAM-1 is necessary for flow-induced vascular remodeling
Q35575626Prediction of sites of coronary atherosclerosis progression:In vivo profiling of endothelial shear stress, lumen, and outer vessel wall characteristics to predict vascular behavior
Q70792836Reduction of monocyte adhesion to xenogenic tissue by endothelialization: an adhesion molecule and time-dependent mechanism
Q40990159Regulation and selectivity of leukocyte emigration
Q43122031Regulation of ICAM-1 in cells of the monocyte/macrophage system in microgravity
Q41120279Regulation of expression of the human monocyte chemotactic protein-1 receptor (hCCR2) by cytokines
Q50880190Relationship between aortic stiffness and the development of coronary collateral in patients with coronary artery disease.
Q36095665Relative reduction of endothelial nitric-oxide synthase expression and transcription in atherosclerosis-prone regions of the mouse aorta and in an in vitro model of disturbed flow.
Q73400434Rheologic considerations in organ preservation
Q38715461Role of biomechanical forces in the natural history of coronary atherosclerosis.
Q40825416Role of shear stress and immune responses in liver regeneration after a partial hepatectomy
Q31004986Selection of phage-displayed peptides on live adherent cells in microfluidic channels
Q46138182Serum level of soluble intercellular adhesion molecule-1 correlates with pulmonary arterial pressure in children with congenital heart disease
Q44491403Shear stress increases expression of a KATP channel in rat and bovine pulmonary vascular endothelial cells
Q37363474Shear stress induction of the tissue factor gene
Q21134771Shear stress modulation of IL-1β-induced E-selectin expression in human endothelial cells
Q47743000Shear stress-induced shedding of soluble intercellular adhesion molecule-1 from saphenous vein endothelium
Q42477880Shear stress-mediated changes in the expression of leukocyte adhesion receptors on human umbilical vein endothelial cells in vitro
Q38235814Single-cell imaging of mechanotransduction in endothelial cells
Q34625853Skeletal muscle cells express ICAM-1 after muscle overload and ICAM-1 contributes to the ensuing hypertrophic response
Q89982955Sonoselective transfection of cerebral vasculature without blood-brain barrier disruption
Q90241493Strategies for Selecting Membrane Protein-Specific Antibodies using Phage Display with Cell-Based Panning
Q88766282Stress phase angle regulates differentiation of human adipose-derived stem cells toward endothelial phenotype
Q30305621Stretch-activated signaling of nerve growth factor secretion in bladder and vascular smooth muscle cells from hypertensive and hyperactive rats
Q42196490Systems analysis of the role of bone morphogenic protein 4 in endothelial inflammation
Q58555364TNF-α-Induced YAP/TAZ Activity Mediates Leukocyte-Endothelial Adhesion by Regulating VCAM1 Expression in Endothelial Cells
Q37318182Targeting and imaging signature caveolar molecules in lungs
Q95643268Targeting functionalized nanoparticles to activated endothelial cells under high wall shear stress
Q39328028Targeting of ICAM-1 on vascular endothelium under static and shear stress conditions using a liposomal Gd-based MRI contrast agent
Q51066077The Assembly and Application of 'Shear Rings': A Novel Endothelial Model for Orbital, Unidirectional and Periodic Fluid Flow and Shear Stress.
Q34048522The Gordon Wilson lecture. Understanding vascular endothelium: a pilgrim's progress. Endothelial dysfunction, biomechanical forces and the pathobiology of atherosclerosis.
Q35193982The NF-kappa B signal transduction pathway in aortic endothelial cells is primed for activation in regions predisposed to atherosclerotic lesion formation.
Q36837870The chemokine system in arteriogenesis and hind limb ischemia
Q34028211The cis-acting phorbol ester "12-O-tetradecanoylphorbol 13-acetate"-responsive element is involved in shear stress-induced monocyte chemotactic protein 1 gene expression
Q27335910The direction of migration of T-lymphocytes under flow depends upon which adhesion receptors are engaged
Q35822234The local physicochemical environment conditions the proinflammatory response of endothelial cells and thus modulates leukocyte recruitment
Q33843570The pathophysiology of the collateral circulation (arteriogenesis).
Q24629974The response-to-retention hypothesis of early atherogenesis
Q36563042The role of endothelial mechanosensitive genes in atherosclerosis and omics approaches
Q28087578The role of epigenetics in the endothelial cell shear stress response and atherosclerosis
Q33870602The role of plaque rupture and thrombosis in coronary artery disease
Q42022713Therapeutic angiogenesis in cardiovascular disease
Q36507703Thermal facilitation of lymphocyte trafficking involves temporal induction of intravascular ICAM-1.
Q35040815Tissue engineering strategies for in vivo neovascularisation
Q46423068Tryptophan depletion under conditions that imitate insulin resistance enhances fatty acid oxidation and induces endothelial dysfunction through reactive oxygen species-dependent and independent pathways.
Q42548612Use of a special bioreactor for the cultivation of a new flexible polyurethane scaffold for aortic valve tissue engineering
Q36751693Vasa vitae--keeping the channels open
Q53578881Vascular bed origin dictates flow pattern regulation of endothelial adhesion molecule expression.
Q33679387Vascular endothelium, hemodynamic forces, and atherogenesis
Q30276705Vascular growth responses to chronic arterial occlusion are unaffected by myeloid specific focal adhesion kinase (FAK) deletion
Q56891683Vasoactive effects of fibrinogen on saphenous vein
Q41669799Vein grafts: haemodynamic forces on the endothelium--a review
Q38601415Wall shear stress in the human eye microcirculation in vivo, segmental heterogeneity and performance of in vitro cerebrovascular models
Q80106732[Inflammation in acute coronary syndromes: mechanisms and clinical implications]