Hemodynamic forces in endothelial dysfunction and vascular aging

scientific article published on October 2010

Hemodynamic forces in endothelial dysfunction and vascular aging is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.EXGER.2010.09.010
P932PMC publication ID3026900
P698PubMed publication ID20888896
P5875ResearchGate publication ID47299447

P2093author name stringEllie Tzima
Caitlin Collins
P2860cites workIncrease of reactive oxygen species (ROS) in endothelial cells by shear flow and involvement of ROS in shear-induced c-fos expressionQ42544016
Shear stress-induced endothelial cell polarization is mediated by Rho and Rac but not Cdc42 or PI 3-kinasesQ42917027
Shear stress-mediated cytoskeletal remodeling and cortactin translocation in pulmonary endothelial cellsQ43936976
A mechanosensory complex that mediates the endothelial cell response to fluid shear stressQ46494451
Localized cdc42 activation, detected using a novel assay, mediates microtubule organizing center positioning in endothelial cells in response to fluid shear stress.Q46499640
Tyrosine phosphorylation of platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) in mechanically stimulated vascular endothelial cellsQ48053148
Mechanism of endothelial cell shape change and cytoskeletal remodeling in response to fluid shear stress.Q52520253
The elongation and orientation of cultured endothelial cells in response to shear stress.Q53769156
Haemodynamic shear stress activates a K+ current in vascular endothelial cells.Q54128151
Wall shear stress rather than shear rate regulates cytoplasmic Ca++ responses to flow in vascular endothelial cellsQ70575563
Shear stress modulates endothelial cell morphology and F-actin organization through the regulation of focal adhesion-associated proteinsQ71682428
Fluid shear stress stimulates mitogen-activated protein kinase in endothelial cellsQ71730250
Endothelial cell signaling and cytoskeletal changes in response to shear stressQ72812136
Platelet-derived growth factor B chain promoter contains a cis-acting fluid shear-stress-responsive elementQ72890972
Involvement of stretch-activated ion channels in Ca2+ mobilization to mechanical stretch in endothelial cellsQ72965878
Nitric oxide activates telomerase and delays endothelial cell senescenceQ73015354
PKC-epsilon is required for mechano-sensitive activation of ERK1/2 in endothelial cellsQ73934960
Fluid shear stress activates Ca(2+) influx into human endothelial cells via P2X4 purinoceptorsQ24290168
Endothelial cell senescence in human atherosclerosis: role of telomere in endothelial dysfunctionQ24292963
Prolonged fluid shear stress induces a distinct set of endothelial cell genes, most specifically lung Krüppel-like factor (KLF2)Q28217790
Fluid shear stress activation of focal adhesion kinase. Linking to mitogen-activated protein kinasesQ28255035
Focal adhesions, contractility, and signalingQ28299775
Activation of integrins in endothelial cells by fluid shear stress mediates Rho-dependent cytoskeletal alignmentQ28348367
Activation of Rac1 by shear stress in endothelial cells mediates both cytoskeletal reorganization and effects on gene expression.Q30453215
Hydrodynamic hyperpolarization of endothelial cellsQ33559943
Distinct roles for the small GTPases Cdc42 and Rho in endothelial responses to shear stressQ33849349
Shear stress regulates the endothelial Kir2.1 ion channelQ34065567
L-arginine as a nutritional prophylaxis against vascular endothelial dysfunction with agingQ34070390
Shear stress selectively upregulates intercellular adhesion molecule-1 expression in cultured human vascular endothelial cellsQ34229735
Mechanotransduction Across the Cell Surface and Through the CytoskeletonQ34306171
Flow-mediated endothelial mechanotransductionQ34648558
G protein-coupled receptors sense fluid shear stress in endothelial cellsQ35108277
Nuclear factor-kappa B interacts functionally with the platelet-derived growth factor B-chain shear-stress response element in vascular endothelial cells exposed to fluid shear stress.Q35753630
Modulation of GTPase activity of G proteins by fluid shear stress and phospholipid compositionQ35924452
Role of small GTPases in endothelial cytoskeletal dynamics and the shear stress responseQ36385575
Regulation of endothelin 1 gene by fluid shear stress is transcriptionally mediated and independent of protein kinase C and cAMP.Q36388240
KLF2 Is a novel transcriptional regulator of endothelial proinflammatory activationQ36399199
Vascular cell senescence: contribution to atherosclerosisQ36699740
Shear-stress causes polarized change in cytoplasmic calcium concentration in human umbilical vein endothelial cells (HUVECs).Q36885997
Adaptation of endothelium to exercise training: insights from experimental studies.Q36991791
Oxidative stress in vascular disease: causes, defense mechanisms and potential therapiesQ37156415
Aging impairs flow-induced dilation in coronary arterioles: role of NO and H(2)O(2).Q37372348
Roles of oxidative stress and redox regulation in atherosclerosisQ37596240
The effect of physical exercise on endothelial function.Q37598237
Hemodynamic shear stress and its role in atherosclerosisQ40786692
Cellular tensegrity: defining new rules of biological design that govern the cytoskeleton.Q40817771
A flow-activated chloride-selective membrane current in vascular endothelial cellsQ41698008
Shear stress-mediated changes in the expression of leukocyte adhesion receptors on human umbilical vein endothelial cells in vitroQ42477880
P433issue2-3
P921main subjectendotheliumQ111140
hemodynamicsQ1642137
P304page(s)185-188
P577publication date2010-10-01
P1433published inExperimental GerontologyQ15766996
P1476titleHemodynamic forces in endothelial dysfunction and vascular aging
P478volume46

Reverse relations

cites work (P2860)
Q91767659Age-Related Impairment of Structure and Function of Iliac Artery Endothelium in Rats Is Improved by Elevated Fluid Shear Stress
Q36528268Aging enhances contraction to thromboxane A2 in aorta from female senescence-accelerated mice
Q49449955Carotid artery wall shear stress is independently correlated with renal function in the elderly
Q36515203Central hemodynamics in prehypertension: effect of the β-adrenergic antagonist nebivolol
Q57821391Computing of Low Shear Stress-Driven Endothelial Gene Network Involved in Early Stages of Atherosclerotic Process
Q42423656Endothelial cell senescence is associated with disrupted cell-cell junctions and increased monolayer permeability
Q35713002Endothelial nitric oxide and 15-lipoxygenase-1 metabolites independently mediate relaxation of the rabbit aorta
Q93033891Endothelial progerin expression causes cardiovascular pathology through an impaired mechanoresponse
Q64928360Endothelial senescence is induced by phosphorylation and nuclear export of telomeric repeat binding factor 2-interacting protein.
Q47309866Mechanisms of Hypothermic Machine Perfusion to Decrease Donation After Cardiac Death Graft Inflammation: Through the Pathway of Upregulating Expression of KLF2 and Inhibiting TGF-β Signaling
Q35324163Mechanistic analysis of nonoxygenated hypothermic machine perfusion's protection on warm ischemic kidney uncovers greater eNOS phosphorylation and vasodilation
Q35749601Mechanosignaling in the vasculature: emerging concepts in sensing, transduction and physiological responses
Q47177685Opportunities for Therapeutic Intervention During Machine Perfusion
Q48214383Pretreatment Donors after Circulatory Death with Simvastatin Alleviates Liver Ischemia Reperfusion Injury through a KLF2-Dependent Mechanism in Rat.
Q33570472Selected activities of Citrus maxima Merr. fruits on human endothelial cells: enhancing cell migration and delaying cellular aging
Q37999318The Splicing Factor SRSF1 as a Marker for Endothelial Senescence
Q36577694The interrelationship between air temperature and humidity as applied locally to the skin: the resultant response on skin temperature and blood flow with age differences
Q36006533The intersection between aging and cardiovascular disease
Q99629066Time-dependent replicative senescence vs. disturbed flow-induced pre-mature aging in atherosclerosis