The direction of migration of T-lymphocytes under flow depends upon which adhesion receptors are engaged

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The direction of migration of T-lymphocytes under flow depends upon which adhesion receptors are engaged is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1039/C4IB00201F
P8608Fatcat IDrelease_uwijhrmhyrcrrdcqz7juhplksy
P932PMC publication ID4746477
P698PubMed publication ID25674729
P5875ResearchGate publication ID271601033

P50authorGeorge A DominguezQ63737225
P2093author name stringDaniel A Hammer
Nicholas R Anderson
P2860cites workEffect of adhesion and chemokine presentation on T-lymphocyte haptokinesisQ27335954
Structure of a Complete Integrin Ectodomain in a Physiologic Resting State and Activation and Deactivation by Applied ForcesQ27653293
Cell migration: integrating signals from front to backQ27860670
Lymph node chemokines promote sustained T lymphocyte motility without triggering stable integrin adhesiveness in the absence of shear forcesQ28115946
T-Cell Function and Migration — Two Sides of the Same CoinQ29041098
Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigmQ29547181
Getting to the site of inflammation: the leukocyte adhesion cascade updatedQ29547271
Lymphocyte homing and homeostasisQ29619924
Integrin-ligand binding properties govern cell migration speed through cell-substratum adhesivenessQ29620446
Activated integrin VLA-4 localizes to the lamellipodia and mediates T cell migration on VCAM-1.Q30489732
Shear stress selectively upregulates intercellular adhesion molecule-1 expression in cultured human vascular endothelial cellsQ34229735
Cell motility: can Rho GTPases and microtubules point the way?Q34446699
Interplay between shear stress and adhesion on neutrophil locomotionQ35545470
A two-step adhesion cascade for T cell/endothelial cell interactions under flow conditionsQ35824653
Intracellular signalling controlling integrin activation in lymphocytesQ36167584
The integrin VLA-4 supports tethering and rolling in flow on VCAM-1.Q36235481
Immune cell migration in inflammation: present and future therapeutic targetsQ36348737
Cytokines and endothelial cell biologyQ36565690
Maintenance and modulation of T cell polarityQ36629861
Force as a facilitator of integrin conformational changes during leukocyte arrest on blood vessels and antigen-presenting cellsQ36714858
Mechanisms of Leukocyte Transendothelial MigrationQ36772665
Leukocyte integrins and their ligand interactionsQ37382190
Modulation of T cell signaling by the actin cytoskeleton.Q38101924
Low shear stress up-regulation of proinflammatory gene expression in human retinal microvascular endothelial cellsQ38152852
Vascular Endothelial Morphology as an Indicator of the Pattern of Blood FlowQ39363540
The microcirculation and inflammation: modulation of leukocyte-endothelial cell adhesion.Q40752165
Alpha 4 beta 1 integrin/VCAM-1 interaction activates alpha L beta 2 integrin-mediated adhesion to ICAM-1 in human T cellsQ40908069
The spontaneously adhesive leukocyte function-associated antigen-1 (LFA-1) integrin in effector T cells mediates rapid actin- and calmodulin-dependent adhesion strengthening to ligand under shear flowQ41016914
Rap1 translates chemokine signals to integrin activation, cell polarization, and motility across vascular endothelium under flowQ41789594
Chemoattractants induce a rapid and transient upregulation of monocyte alpha4 integrin affinity for vascular cell adhesion molecule 1 which mediates arrest: an early step in the process of emigrationQ42021031
Integrin cross talk: activation of lymphocyte function-associated antigen-1 on human T cells alters alpha4beta1- and alpha5beta1-mediated function.Q42795898
T lymphocytes orient against the direction of fluid flow during LFA-1-mediated migrationQ42929091
alpha 4 integrins mediate lymphocyte attachment and rolling under physiologic flowQ46523925
Volume flow and wall shear stress quantification in the human conjunctival capillaries and post-capillary venules in vivo.Q50653217
Transendothelial migration of lymphocytes mediated by intraendothelial vesicle stores rather than by extracellular chemokine depots.Q50979816
Differential roles for endothelial ICAM-1, ICAM-2, and VCAM-1 in shear-resistant T cell arrest, polarization, and directed crawling on blood-brain barrier endothelium.Q51036574
Homeostatic lymphoid chemokines synergize with adhesion ligands to trigger T and B lymphocyte chemokinesis.Q51151692
The Dynamic Response of Vascular Endothelial Cells to Fluid Shear StressQ70917222
Expression of ICAM-1 and VCAM-1 and monocyte adherence in arteries exposed to altered shear stressQ71693098
Endothelial P-selectin and VCAM-1 each can function as primary adhesive mechanisms for T cells under conditions of flowQ73043027
The LFA-1 integrin supports rolling adhesions on ICAM-1 under physiological shear flow in a permissive cellular environmentQ73910781
VLA-4 (alpha(4)beta(1)) engagement defines a novel activation pathway for beta(2) integrin-dependent leukocyte adhesion involving the urokinase receptorQ73971405
The affinity of integrin alpha(4)beta(1) governs lymphocyte migrationQ74388291
High affinity very late antigen-4 subsets expressed on T cells are mandatory for spontaneous adhesion strengthening but not for rolling on VCAM-1 in shear flowQ77899695
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectbiophysicsQ7100
P304page(s)345-355
P577publication date2015-02-12
P1433published inIntegrative BiologyQ1524032
P1476titleThe direction of migration of T-lymphocytes under flow depends upon which adhesion receptors are engaged
P478volume7

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cites work (P2860)
Q98394720Evaluation of cytotoxic T lymphocyte-mediated anticancer response against tumor interstitium-simulating physical barriers
Q90490062Human Neutrophils Will Crawl Upstream on ICAM-1 If Mac-1 Is Blocked
Q36329068Human cytotoxic T-lymphocyte membrane-camouflaged nanoparticles combined with low-dose irradiation: a new approach to enhance drug targeting in gastric cancer
Q92002622Integrating Biological Advances Into the Clinical Management of Breast Cancer Related Lymphedema
Q54207309LFA-1 in T Cell Migration and Differentiation.
Q47309416Migration against the direction of flow is LFA-1-dependent in human hematopoietic stem and progenitor cells
Q91223287Regulation of cell adhesion: a collaborative effort of integrins, their ligands, cytoplasmic actors, and phosphorylation
Q92065304Stable contacts of naïve CD4 T cells with migratory dendritic cells are ICAM-1-dependent but dispensable for proliferation in vivo
Q39008870Stem Cells as a Promising Tool for the Restoration of Brain Neurovascular Unit and Angiogenic Orientation.
Q64902321T lymphocytes migrate upstream after completing the leukocyte adhesion cascade.
Q92698849The Inflammatory Response After Ischemic Stroke: Targeting β2 and β1 Integrins
Q48353956The opposing forces of shear flow and sphingosine-1-phosphate control marginal zone B cell shuttling
Q64993454Tumor progression mechanisms: Insights from the central immune regulation of tissue homeostasis.

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