Overexpression of gelsolin reduces the proliferation and invasion of colon carcinoma cells

scientific article published on 19 August 2016

Overexpression of gelsolin reduces the proliferation and invasion of colon carcinoma cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3892/MMR.2016.5652
P932PMC publication ID5042772
P698PubMed publication ID27573444

P2093author name stringWei-Xin Niu
Xin-Yu Qin
Tuo Yi
Wen-Xiang Li
Sheng-Li Lin
Tian-Geng Dong
Meng-Xuan Yang
Xin-Qiang Hong
P2860cites workGelsolin: a candidate for suppressor of human bladder cancer.Q41319586
Holo-retinol-binding protein and its receptor STRA6 drive oncogenic transformation.Q42971403
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Tissue microarray analysis of cytoskeletal actin-associated biomarkers gelsolin and E-cadherin in urothelial carcinomaQ46818029
Atypical cutaneous lymphoid hyperplasia induced by chemotherapy in a patient with advanced colon carcinomaQ46881599
Colorectal cancerQ57191694
Control of cytoplasmic actin gel–sol transformation by gelsolin, a calcium-dependent regulatory proteinQ59064148
Gelsolin functions as a metastasis suppressor in B16-BL6 mouse melanoma cells and requirement of the carboxyl-terminus for its effectQ64129099
Carcinoma of the colon: long-term survival and prognosis after surgical treatment in a series of 798 patientsQ68551569
Frequent loss of gelsolin expression in non-small cell lung cancers of heavy smokersQ74093433
Cancer metastasis: a search for therapeutic inhibitionQ74553302
STAT3 controls matrix metalloproteinase-1 expression in colon carcinoma cells by both direct and AP-1-mediated interaction with the MMP-1 promoterQ83629989
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodQ25938999
Gelsolin, a multifunctional actin regulatory proteinQ28137815
Gelsolin inhibits apoptosis by blocking mitochondrial membrane potential loss and cytochrome c releaseQ28144360
The matrix corroded: podosomes and invadopodia in extracellular matrix degradationQ28286690
Targeting signal-transducer-and-activator-of-transcription-3 for prevention and therapy of cancer: modern target but ancient solutionQ28291780
Cancer statistics, 2005Q29617572
STAT 3 as a target for cancer drug discoveryQ33333915
Functions of gelsolin: motility, signaling, apoptosis, cancerQ33536511
Critical determinants of cancer metastasis: rationale for therapyQ33651963
Colon cancer survival rates with the new American Joint Committee on Cancer sixth edition stagingQ33982101
Adipokine regulation of colon cancer: adiponectin attenuates interleukin-6-induced colon carcinoma cell proliferation via STAT-3Q34013713
Activated STAT signaling in human tumors provides novel molecular targets for therapeutic interventionQ34595904
Altered expression of miR-21, miR-31, miR-143 and miR-145 is related to clinicopathologic features of colorectal cancerQ34736348
Heparanase powers a chronic inflammatory circuit that promotes colitis-associated tumorigenesis in miceQ34876266
RKIP phosphorylation and STAT3 activation is inhibited by oxaliplatin and camptothecin and are associated with poor prognosis in stage II colon cancer patientsQ35010521
Cell migration in the forebrainQ35081536
Signal transducer and activator of transcription-3, inflammation, and cancer: how intimate is the relationship?.Q35120899
Systemic therapy for colorectal cancerQ36029007
A role for gelsolin in actuating epidermal growth factor receptor-mediated cell motilityQ36237218
Touched and moved by STAT3.Q36533730
Regulation of the actin cytoskeleton in cancer cell migration and invasionQ36574131
Efficient killing of SW480 colon carcinoma cells by a signal transducer and activator of transcription (STAT) 3 hairpin decoy oligodeoxynucleotide--interference with interferon-gamma-STAT1-mediated killing.Q38353710
Gelsolin as a negative prognostic factor and effector of motility in erbB-2-positive epidermal growth factor receptor-positive breast cancersQ38460154
Anti-EGFR therapeutic efficacy correlates directly with inhibition of STAT3 activity.Q39022069
Pien Tze Huang suppresses IL-6-inducible STAT3 activation in human colon carcinoma cells through induction of SOCS3.Q39268105
Electrostatic assembly of a DNA superparamagnetic nano-tool for simultaneous intracellular delivery and in situ monitoringQ39411561
Cell–cell contacts induce STAT3 activity in colon carcinoma cells through an autocrine stimulation loopQ39657328
Prognosis in patients with obstructing colorectal carcinomaQ40333463
siRNA gelsolin knockdown induces epithelial-mesenchymal transition with a cadherin switch in human mammary epithelial cellsQ40363300
Mechanisms of gelsolin-dependent and -independent EGF-stimulated cell motility in a human lung epithelial cell lineQ40415933
The plasma and cytoplasmic forms of human gelsolin differ in disulfide structureQ41182724
P433issue4
P921main subjectoverexpressionQ61643320
colon carcinomaQ18554829
P304page(s)3059-3065
P577publication date2016-08-19
P1433published inMolecular Medicine ReportsQ26842180
P1476titleOverexpression of gelsolin reduces the proliferation and invasion of colon carcinoma cells
P478volume14

Reverse relations

cites work (P2860)
Q51081156Epithelial cell types and their proposed roles in maintaining the mucosal barrier in human chagasic-megacolonic mucosa.
Q94593576Gelsolin Promotes Cancer Progression by Regulating Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma and Correlates with a Poor Prognosis
Q47364413Gelsolin regulates proliferation, apoptosis and invasion in NK/T-cell lymphoma cells.
Q64237899Lower Expression of Gelsolin in Colon Cancer and Its Diagnostic Value in Colon Cancer Patients
Q58702505Plasma Gelsolin: Indicator of Inflammation and Its Potential as a Diagnostic Tool and Therapeutic Target

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