TAT-Hsp70 induces neuroprotection against stroke via anti-inflammatory actions providing appropriate cellular microenvironment for transplantation of neural precursor cells

scientific article published on 24 July 2013

TAT-Hsp70 induces neuroprotection against stroke via anti-inflammatory actions providing appropriate cellular microenvironment for transplantation of neural precursor cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/JCBFM.2013.126
P932PMC publication ID3824176
P698PubMed publication ID23881248
P5875ResearchGate publication ID251569032

P2093author name stringMathias Bähr
Dirk M Hermann
Britta Kaltwasser
Thorsten R Doeppner
Jin Fengyan
P2860cites workThe molecular chaperone Hsp90 plays a role in the assembly and maintenance of the 26S proteasomeQ24681597
Toll-like receptors in the induction of the innate immune responseQ28144797
Heat shock proteins and protection of the nervous systemQ28237891
Anti-inflammatory effects of the 70 kDa heat shock protein in experimental strokeQ28576568
Neuroprotection achieved with a novel proteasome inhibitor which blocks NF-kappaB activationQ30839042
Optimizing the success of cell transplantation therapy for strokeQ33636930
Combination treatment with VELCADE and low-dose tissue plasminogen activator provides potent neuroprotection in aged rats after embolic focal ischemiaQ33814642
Delivery of bioactive molecules into the cell: the Trojan horse approachQ34358962
Heat shock protein 72 (Hsp72) improves long term recovery after focal cerebral ischemia in miceQ34505543
The NF-kappa B activation pathway: a paradigm in information transfer from membrane to nucleusQ34543723
Roles of heat-shock proteins in innate and adaptive immunityQ34576423
Enhancement of endogenous neurogenesis in ephrin-B3 deficient mice after transient focal cerebral ischemiaQ35795169
Toll-like receptor 2 deficiency leads to delayed exacerbation of ischemic injury.Q36281490
Neuroprotection with the proteasome inhibitor MLN519 in focal ischemic brain injury: relation to nuclear factor kappaB (NF-kappaB), inflammatory gene expression, and leukocyte infiltrationQ36499413
Regulation of apoptotic and inflammatory cell signaling in cerebral ischemia: the complex roles of heat shock protein 70Q36923921
Synthesis of cell-penetrating peptides and their application in neurobiologyQ37098169
Protein aggregation and proteasome dysfunction after brain ischemiaQ37161571
Toll-like receptor signaling in endogenous neuroprotection and strokeQ37171364
Anti-inflammatory properties and pharmacological induction of Hsp70 after brain injuryQ37975959
The novel proteasome inhibitor BSc2118 protects against cerebral ischaemia through HIF1A accumulation and enhanced angioneurogenesisQ38061412
Chronic behavioral testing after focal ischemia in the mouse: functional recovery and the effects of genderQ39128180
Transduction of neural precursor cells with TAT-heat shock protein 70 chaperone: therapeutic potential against ischemic stroke after intrastriatal and systemic transplantationQ39347126
Quantitative evaluation of chaperone activity and neuroprotection by different preparations of a cell-penetrating Hsp70.Q39985518
Tat-Hsp70 protects dopaminergic neurons in midbrain cultures and in the substantia nigra in models of Parkinson's disease.Q40027318
Neuroprotective effects of virally delivered HSPs in experimental strokeQ40389152
Mice overexpressing rat heat shock protein 70 are protected against cerebral infarctionQ41741332
Acute hepatocyte growth factor treatment induces long-term neuroprotection and stroke recovery via mechanisms involving neural precursor cell proliferation and differentiation.Q42030894
Cold-induced apoptosis of rat liver endothelial cells: involvement of the proteasomeQ44493615
Delayed post-ischaemic neuroprotection following systemic neural stem cell transplantation involves multiple mechanismsQ44736716
Human neural stem cells improve sensorimotor deficits in the adult rat brain with experimental focal ischemiaQ44972813
TAT-Hsp70-mediated neuroprotection and increased survival of neuronal precursor cells after focal cerebral ischemia in miceQ46041604
Tripeptide mimetics inhibit the 20 S proteasome by covalent bonding to the active threoninesQ46513051
Transplantation of TAT-Bcl-xL-transduced neural precursor cells: long-term neuroprotection after strokeQ48163222
Spatio-temporal distribution of inflammatory reaction and expression of TLR2/4 signaling pathway in rat brain following permanent focal cerebral ischemiaQ48238642
Reduced cerebral ischemia-reperfusion injury in Toll-like receptor 4 deficient miceQ48328543
A test for detecting long-term sensorimotor dysfunction in the mouse after focal cerebral ischemiaQ48558910
Recombinant tissue plasminogen activator induces blood-brain barrier breakdown by a matrix metalloproteinase-9-independent pathway after transient focal cerebral ischemia in mouseQ48914597
Anti-VEGF receptor antagonist (VGA1155) reduces infarction in rat permanent focal brain ischemiaQ48937703
Early blood-brain barrier disruption in human focal brain ischemiaQ80609599
Toll-like receptor 2 mediates CNS injury in focal cerebral ischemiaQ81249251
P4510describes a project that usesImageJQ1659584
P433issue11
P921main subjectinflammationQ101991
P304page(s)1778-1788
P577publication date2013-07-24
P1433published inJournal of Cerebral Blood Flow & MetabolismQ14663525
P1476titleTAT-Hsp70 induces neuroprotection against stroke via anti-inflammatory actions providing appropriate cellular microenvironment for transplantation of neural precursor cells
P478volume33

Reverse relations

cites work (P2860)
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Q34566120Extracellular mycobacterial DnaK polarizes macrophages to the M2-like phenotype
Q91643282From Tumor Metastasis towards Cerebral Ischemia-Extracellular Vesicles as a General Concept of Intercellular Communication Processes
Q90435042Gallic acid, a common dietary phenolic protects against high fat diet induced DNA damage
Q91649590Heat shock protein 70 increases cell proliferation, neuroblast differentiation, and the phosphorylation of CREB in the hippocampus
Q30395196Heat shock protein concentration and clarity of porcine lenses incubated at elevated temperatures
Q48488593Ischemic Post-Conditioning Induces Post-Stroke Neuroprotection via Hsp70-Mediated Proteasome Inhibition and Facilitates Neural Progenitor Cell Transplantation.
Q38250196Molecular regulation of cell fate in cerebral ischemia: role of the inflammasome and connected pathways
Q53757262Neural stem cell therapies and hypoxic-ischemic brain injury.
Q41087764Preinduction of heat shock protein 70 protects mice against post-infection irritable bowel syndrome via NF-κB and NOS/NO signaling pathways
Q35612189TAT-HSP70 Attenuates Experimental Lung Injury
Q36350527The indirect NMDAR antagonist acamprosate induces postischemic neurologic recovery associated with sustained neuroprotection and neuroregeneration.
Q42269178The indirect NMDAR inhibitor flupirtine induces sustained post-ischemic recovery, neuroprotection and angioneurogenesis.

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