Toll-like receptors in the induction of the innate immune response

scientific article (publication date: 17 August 2000)

Toll-like receptors in the induction of the innate immune response is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P6179Dimensions Publication ID1011195594
P356DOI10.1038/35021228
P3181OpenCitations bibliographic resource ID1273869
P698PubMed publication ID10963608
P5875ResearchGate publication ID12357672

P2093author name stringR J Ulevitch
A Aderem
P2860cites workThe kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathwayQ22009096
TLR6: A novel member of an expanding toll-like receptor familyQ22009499
MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4Q22009943
IRAK-M is a novel member of the Pelle/interleukin-1 receptor-associated kinase (IRAK) familyQ22010176
Host defense mechanisms triggered by microbial lipoproteins through toll-like receptorsQ22010442
ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathwayQ22010492
The Envelope of MycobacteriaQ22241995
Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 GeneQ22299417
A family of human receptors structurally related to Drosophila TollQ24321888
Structure and function of lipopolysaccharide binding proteinQ24324774
The human toll signaling pathway: divergence of nuclear factor kappaB and JNK/SAPK activation upstream of tumor necrosis factor receptor-associated factor 6 (TRAF6)Q24647122
Physical contact between lipopolysaccharide and toll-like receptor 4 revealed by genetic complementationQ24670236
A human homologue of the Drosophila Toll protein signals activation of adaptive immunityQ28131769
Innate immune recognition: mechanisms and pathwaysQ28138782
Phylogenetic perspectives in innate immunityQ28144345
The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adultsQ28289939
TRAF6 is a signal transducer for interleukin-1Q28291934
Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall componentsQ28511151
TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signalingQ28513445
Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complexQ28588629
MyD88: an adapter that recruits IRAK to the IL-1 receptor complexQ28611795
CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding proteinQ29615189
MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathwaysQ29616209
Mechanisms of phagocytosis in macrophagesQ29618100
Recognition of gram-negative bacteria and endotoxin by the innate immune systemQ33536549
Lipid A diversity and the innate host response to bacterial infectionQ33538559
Toll signaling pathways in the innate immune responseQ33840523
Signaling mechanisms in the antimicrobial host defense of DrosophilaQ33840625
Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharideQ33938936
The 18-wheeler mutation reveals complex antibacterial gene regulation in Drosophila host defenseQ34250201
Biochemistry of endotoxinsQ34564256
Identification and characterization of the dTDP-rhamnose biosynthesis and transfer genes of the lipopolysaccharide-related rfb locus in Leptospira interrogans serovar CopenhageniQ35620034
Signal transduction in macrophages by glycosylphosphatidylinositols of Plasmodium, Trypanosoma, and Leishmania: activation of protein tyrosine kinases and protein kinase C by inositolglycan and diacylglycerol moietiesQ36108842
Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)Q36367812
Toll-like receptor-2 mediates mycobacteria-induced proinflammatory signaling in macrophages.Q36746122
Receptor-dependent mechanisms of cell stimulation by bacterial endotoxinQ40402483
TAK1 mediates an activation signal from toll-like receptor(s) to nuclear factor-kappaB in lipopolysaccharide-stimulated macrophagesQ40900102
The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens.Q40919510
Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharideQ40990203
Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signallingQ41006478
Genetic organization of the lipopolysaccharide O-antigen biosynthetic locus of Leptospira borgpetersenii serovar Hardjobovis.Q42608444
Constitutive activation of toll-mediated antifungal defense in serpin-deficient DrosophilaQ43169504
Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products.Q55033421
Human toll-like receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide.Q64905980
Cutting edge: preferentially the R-stereoisomer of the mycoplasmal lipopeptide macrophage-activating lipopeptide-2 activates immune cells through a toll-like receptor 2- and MyD88-dependent signaling pathwayQ73330320
Unresponsiveness of MyD88-deficient mice to endotoxinQ78093558
P433issue6797
P407language of work or nameEnglishQ1860
P921main subjecttoll-like receptorQ408004
P304page(s)782-7
P577publication date2000-08-17
P1433published inNatureQ180445
P1476titleToll-like receptors in the induction of the innate immune response
P478volume406

Reverse relations

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Q64108120Dependence of the severity of the systemic inflammatory response on resistance to hypoxia in male Wistar rats
Q37564723Deregulation of SOCS5 suppresses dendritic cell function in chronic lymphocytic leukemia
Q39414910Detection of Lipid and Amphiphilic Biomarkers for Disease Diagnostics
Q81163070Deviation from major codons in the Toll-like receptor genes is associated with low Toll-like receptor expression
Q40332607Diesel exhaust enhances virus- and poly(I:C)-induced Toll-like receptor 3 expression and signaling in respiratory epithelial cells
Q90422421Diet-induced Generalized Periodontitis in Lewis Rats
Q31108939Dietary heme alters microbiota and mucosa of mouse colon without functional changes in host-microbe cross-talk
Q60305335Differential Expression of Woodchuck Toll-Like Receptors 1-10 in Distinct Forms of Infection and Stages of Hepatitis in Experimental Hepatitis B Virus Infection
Q39392957Differential cytokine production and Toll-like receptor signaling pathways by Candida albicans blastoconidia and hyphae
Q37675430Differential functional effects of biomaterials on dendritic cell maturation
Q35012183Differential induction of interleukin-10 and interleukin-12 in dendritic cells by microbial toll-like receptor activators and skewing of T-cell cytokine profiles.
Q40673400Differential modulation of Toll-like receptors by fatty acids: preferential inhibition by n-3 polyunsaturated fatty acids
Q40316849Differential modulatory effects of annexin 1 on nitric oxide synthase induction by lipopolysaccharide in macrophages
Q33893955Differential regulation of membrane CD14 expression and endotoxin-tolerance in alveolar macrophages
Q36819882Differential release of mast cell mediators and the pathogenesis of inflammation
Q35801720Differential role of MyD88 in macrophage-mediated responses to opportunistic fungal pathogens
Q37294179Differential roles of TLR2 and TLR4 in acute focal cerebral ischemia/reperfusion injury in mice
Q34596196Digging for innate immunity since Darwin and Metchnikoff
Q24796731Direct Toll-like receptor 2 mediated co-stimulation of T cells in the mouse system as a basis for chronic inflammatory joint disease
Q40596907Direct evidence that toll-like receptor 9 (TLR9) functionally binds plasmid DNA by specific cytosine-phosphate-guanine motif recognition.
Q47911048Direct recognition of LPS by human but not murine CD8+ T cells via TLR4 complex
Q36840989Discovery of new MD2 inhibitor from chalcone derivatives with anti-inflammatory effects in LPS-induced acute lung injury
Q35026979Disease and freeways drive genetic change in urban bobcat populations
Q24302174Distinct molecular mechanism for initiating TRAF6 signalling
Q38915803Distinctive responses of brain tumor cells to TLR2 ligands
Q34387583Disturbance of endothelial barrier function by bacterial toxins and atherogenic mediators: a role for Rho/Rho kinase
Q38881211Docosahexaenoic acid differentially affects TNFα and IL-6 expression in LPS-stimulated RAW 264.7 murine macrophages
Q45647163Does Toll-like receptor 3 play a biological role in virus infections?
Q28566143Double-stranded RNA-activated protein kinase is required for the LPS-induced activation of STAT1 inflammatory signaling in rat brain glial cells
Q35836325Down-regulation of IL-8 expression in human airway epithelial cells through helper-dependent adenoviral-mediated RNA interference
Q52587765Drosophila immunity: two paths to NF-kappaB.
Q34507042Drosophila innate immunity: an evolutionary perspective
Q52764230Drugs in Development for Hepatitis B.
Q50148121Dual effects of a CpG-DNAzyme targeting mutant EGFR transcripts in lung cancer cells: TLR9 activation and EGFR downregulation
Q38292261Duplicated binding sites for (1-->3)-beta-D-glucan in the horseshoe crab coagulation factor G: implications for a molecular basis of the pattern recognition in innate immunity
Q33789614Early Gut Microbiota Intervention Suppresses DSS-Induced Inflammatory Responses by Deactivating TLR/NLR Signalling in Pigs
Q35622686Early life stress inhibits expression of a novel innate immune pathway in the developing hippocampus
Q28587816Ecsit is required for Bmp signaling and mesoderm formation during mouse embryogenesis
Q55258929Effect of Lavender (Lavandula angustifolia) Essential Oil on Acute Inflammatory Response.
Q35686518Effect of anti-gliadin IgY antibody on epithelial intestinal integrity and inflammatory response induced by gliadin
Q36783170Effect of biliary drainage on inducible nitric oxide synthase, CD14 and TGR5 expression in obstructive jaundice rats
Q43577928Effect of carbon dioxide on neonatal mouse lung: a genomic approach.
Q40627929Effect of sesame antioxidants on LPS-induced NO production by BV2 microglial cells
Q41854179Effects of Thymol and Carvacrol, Constituents of Thymus vulgaris L. Essential Oil, on the Inflammatory Response.
Q42547849Effects of cis-9,trans-11 and trans-10,cis-12 conjugated linoleic acid, linoleic acid, phytanic acid and the combination of various fatty acids on proliferation and cytokine expression of bovine peripheral blood mononuclear cells
Q42239379Effects of cyanobacterial lipopolysaccharides from microcystis on glutathione-based detoxification pathways in the zebrafish (Danio rerio) embryo.
Q50483031Effects of dietary β-1,3/1,6-glucan on the antioxidant and digestive enzyme activities of Pacific red snapper (Lutjanus peru) after exposure to lipopolysaccharides.
Q36240129Effects of flagellin on innate and adaptive immunity
Q41823689Effects of ketamine on proinflammatory cytokines and nuclear factor kappaB in polymicrobial sepsis rats
Q57241187Effects of nonpathogenic bacteria on cytokine secretion by human intestinal mucosa
Q46111615Effects of trefoil peptide 3 on expression of TNF-alpha, TLR4, and NF-kappaB in trinitrobenzene sulphonic acid induced colitis mice
Q92527655Elderberry (Sambucus nigra L.) Fruit Extract Alleviates Oxidative Stress, Insulin Resistance, and Inflammation in Hypertrophied 3T3-L1 Adipocytes and Activated RAW 264.7 Macrophages
Q98771484Emerging Adjuvants for Cancer Immunotherapy
Q34093483Endoplasmic reticulum chaperone gp96 is required for innate immunity but not cell viability
Q37823734Endotoxin removal devices for the treatment of sepsis and septic shock
Q35027578Engagement of TLR2 reverses the suppressor function of conjunctiva CD4+CD25+ regulatory T cells and promotes herpes simplex virus epitope-specific CD4+CD25- effector T cell responses
Q35609384Enhanced Toll-like receptor (TLR) responses of TNFR-associated factor 3 (TRAF3)-deficient B lymphocytes
Q40463138Enhanced anti-inflammatory potential of cinnamate-zinc layered hydroxide in lipopolysaccharide-stimulated RAW 264.7 macrophages.
Q30730983Enhancement of antigen-specific immunity via the TLR4 ligands MPL adjuvant and Ribi.529.
Q34516610Enhancement of protein vaccine potency by in vivo electroporation mediated intramuscular injection
Q36780146Enhancing DNA vaccine potency by modifying the properties of antigen-presenting cells
Q33993768Enteric flora in health and disease
Q26830009Enterovirus and type 1 diabetes: What is the matter?
Q30852262Environmental changes, microbiota, and allergic diseases
Q46770898Epidermal growth factor receptor acts as a negative regulator for bacterium nontypeable Haemophilus influenzae-induced Toll-like receptor 2 expression via an Src-dependent p38 mitogen-activated protein kinase signaling pathway
Q36782388Epigenetic modification of TLR4 promotes activation of NF-κB by regulating methyl-CpG-binding domain protein 2 and Sp1 in gastric cancer
Q51837662Epistatic effect of TLR4 and IL4 genes on the risk of asthma in females.
Q51158560Epithelial-specific Toll-like Receptor (TLR)5 Activation Mediates Barrier Dysfunction in Experimental Ileitis.
Q36334853Eriodictyol, a plant flavonoid, attenuates LPS-induced acute lung injury through its antioxidative and anti-inflammatory activity
Q34726541Eritoran tetrasodium (E5564) treatment for sepsis: review of preclinical and clinical studies
Q33711439Escherichia coli and Staphylococcus aureus elicit differential innate immune responses following intramammary infection.
Q54421029Escherichia coli inoculation of porcine mammary glands affects local mRNA expression of Toll-like receptors and regulatory cytokines.
Q40306650Escherichia coli lipopolysaccharide inhibits renin activity in human mesangial cells.
Q50109313Essential role of MD-2 in LPS responsiveness and TLR4 distribution
Q41938509Essential role of STAT1 in caspase-independent cell death of activated macrophages through the p38 mitogen-activated protein kinase/STAT1/reactive oxygen species pathway
Q34478755Essential role of toll-like receptor 2 in morphine-induced microglia activation in mice
Q34174823Essential roles for NF-kappa B and a Toll/IL-1 receptor domain-specific signal(s) in the induction of I kappa B-zeta
Q24299305Establishment of a monoclonal antibody against human Toll-like receptor 3 that blocks double-stranded RNA-mediated signaling
Q45908855Estimation of sCD14 levels in saliva obtained from patients with various periodontal conditions.
Q26801531Evaluating the Oxidative Stress in Inflammation: Role of Melatonin
Q53549531Evaluation of a new inflammatory molecule (triggering receptor expressed on myeloid cells-1) in the diagnosis of pleural effusion.
Q40818856Evidence for an innate immune response in the immature human intestine: toll-like receptors on fetal enterocytes
Q28213451Evidence of a trimolecular complex involving LPS, LPS binding protein and soluble CD14 as an effector of LPS response
Q34401884Evolution of effectors and receptors of innate immunity
Q33755502Evolution of the Kdo2-lipid A biosynthesis in bacteria
Q34449973Evolutionary perspective on innate immune recognition
Q36959680Exploiting dendritic cells for active immunotherapy of cancer and chronic infections
Q43145583Exposure to mycotoxins increases the allergic immune response in a murine asthma model
Q54092600Expression analysis of toll-like receptors of Dengue-infected cornea by real-time polymerase chain reaction.
Q24645038Expression and distribution of Toll-like receptors 11-13 in the brain during murine neurocysticercosis
Q28255954Expression and function of Toll-like receptor on T cells
Q42732945Expression and functional characterization of P2X receptors in mouse alveolar macrophages
Q35749232Expression and regulation of Toll-like receptor 2 in rheumatoid arthritis synovium
Q88032383Expression and regulation of avian beta-defensin 8 protein in immune tissues and cell lines of chickens
Q44412922Expression and subcellular distribution of toll-like receptors TLR4, TLR5 and TLR9 on the gastric epithelium in Helicobacter pylori infection
Q30965642Expression cloning and biochemical characterization of a Rhizobium leguminosarum lipid A 1-phosphatase
Q31058781Expression cloning and characterization of the C28 acyltransferase of lipid A biosynthesis in Rhizobium leguminosarum
Q33622203Expression cloning of three Rhizobium leguminosarum lipopolysaccharide core galacturonosyltransferases
Q41853585Expression of Toll-like receptor 2 (TLR2), TLR4, and CD14 in biopsy samples of patients with inflammatory bowel diseases: upregulated expression of TLR2 in terminal ileum of patients with ulcerative colitis
Q40402030Expression of Toll-like receptor 9 and response to bacterial CpG oligodeoxynucleotides in human intestinal epithelium.
Q54442912Expression of Toll-like receptor 9 in bone marrow cells of myelodysplastic syndromes is down-regulated during transformation to overt leukemia.
Q38397625Expression of Toll-like receptors 2 and 4 and the OPG-RANKL-RANK system in inflammatory external root resorption and external cervical resorption.
Q42420306Expression of Toll-like receptors in verruca and molluscum contagiosum
Q24319761Expression of functional Toll-like receptor 2 on human epidermal keratinocytes
Q37402189Expression of toll-like receptors in human limbal and conjunctival epithelial cells.
Q89809904Expressionof langerhans cell and plasmacytoid dendritic cell markers, and toll-like receptor 7/9 signaling pathway proteins in verruca vulgaris lesions
Q36372642Extra-pulmonary aspects of acquired pulmonary alveolar proteinosis as predicted by granulocyte-macrophage colony-stimulating factor-deficient mice
Q50871361Extracellular Hsp70 inhibits pro-inflammatory cytokine production by IL-10 driven down-regulation of C/EBPβ and C/EBPδ.
Q34120273Extracellular antigens from Salmonella enteritidis induce effective immune response in mice after oral vaccination
Q33747385FXYD5 Is an Essential Mediator of the Inflammatory Response during Lung Injury
Q42243654Facile syntheses of functionalized toll-like receptor 7 agonists
Q34184601Factors predictive of the failure of medical treatment in patients with pleural infection
Q64938060Fermented dried Citrus unshiu peel extracts exert anti-inflammatory activities in LPS-induced RAW264.7 macrophages and improve skin moisturizing efficacy in immortalized human HaCaT keratinocytes.
Q41885000Ferulic acid exerts neuroprotective effects against cerebral ischemia/reperfusion-induced injury via antioxidant and anti-apoptotic mechanisms in vitro and in vivo
Q40476694Fever and circulating cytokines induced by double-stranded RNA in guinea pigs: dependence on the route of administration and effects of repeated injections.
Q28818652First Insights into the Subterranean Crustacean Bathynellacea Transcriptome: Transcriptionally Reduced Opsin Repertoire and Evidence of Conserved Homeostasis Regulatory Mechanisms
Q48248582First identification of Toll-like receptor-4 in avian brain: evolution of lipopolysaccharide recognition and inflammation-dependent responses
Q44813120Flagellin and lipopolysaccharide up-regulation of IL-6 and CXCLi2 gene expression in chicken heterophils is mediated by ERK1/2-dependent activation of AP-1 and NF-kappaB signaling pathways
Q40763973Flagellin fusion proteins as adjuvants or vaccines induce specific immune responses
Q34853145Flagellin of enteropathogenic Escherichia coli stimulates interleukin-8 production in T84 cells
Q34671311Flagellin perception: a paradigm for innate immunity
Q34572728Flagellin stimulates protective lung mucosal immunity: role of cathelicidin-related antimicrobial peptide
Q33535845Flagellin-induced corneal antimicrobial peptide production and wound repair involve a novel NF-kappaB-independent and EGFR-dependent pathway
Q92408896Fosfomycin Protects Mice From Staphylococcus aureus Pneumonia Caused by α-Hemolysin in Extracellular Vesicles by Inhibiting MAPK-Regulated NLRP3 Inflammasomes
Q36499980Fosfomycin enhances phagocyte-mediated killing of Staphylococcus aureus by extracellular traps and reactive oxygen species
Q34574870Free radical production requires both inducible nitric oxide synthase and xanthine oxidase in LPS-treated skin
Q54745927Full-length cDNA cloning of Toll-like receptor 4 in dogs and cats
Q41819144Function of C/EBPdelta in a regulatory circuit that discriminates between transient and persistent TLR4-induced signals
Q37941985Functional adaptations of the transcriptome to mastitis-causing pathogens: the mammary gland and beyond
Q36728683Functional diversification of the toll-like receptor gene family
Q35105388Functional interaction of heat shock protein 90 and Beclin 1 modulates Toll-like receptor-mediated autophagy.
Q40683270Functional polymorphisms of the TLR7 and TLR8 genes contribute to Mycobacterium tuberculosis infection.
Q36585913Fundamental mechanisms of host immune responses to infection
Q34990704Fungi, dendritic cells and receptors: a host perspective of fungal virulence
Q28551831G1-4A, a Polysaccharide from Tinospora cordifolia Inhibits the Survival of Mycobacterium tuberculosis by Modulating Host Immune Responses in TLR4 Dependent Manner
Q34342098GM-CSF priming drives bone marrow-derived macrophages to a pro-inflammatory pattern and downmodulates PGE2 in response to TLR2 ligands
Q43774205GM-CSF regulates alveolar macrophage differentiation and innate immunity in the lung through PU.1.
Q34053156Ganglioside embedded in reconstituted lipoprotein binds cholera toxin with elevated affinity
Q28572427Gangliosides trigger inflammatory responses via TLR4 in brain glia
Q39093045Gardiquimod inhibits the expression of calcium-induced differentiation markers in HaCaT cells
Q89494174Gaudichaudione H Inhibits Inflammatory Responses in Macrophages and Dextran Sodium Sulfate-Induced Colitis in Mice
Q92986340Gene conversion generates evolutionary novelty that fuels genetic conflicts
Q47820784Gene expression in the tuberculous granuloma: analysis by laser capture microdissection and real-time PCR.
Q44451024Gene expression of Toll-like receptors and associated molecules induced by inflammatory stimuli in the primary alveolar macrophage
Q38347887Gene expression profiling detects patterns of human macrophage responses following Mycobacterium tuberculosis infection
Q47137169Gene expression profiling in pbMEC - in search of molecular biomarkers to predict immunoglobulin production in bovine milk
Q61039261Gene expression profiling of plasma cell dyscrasias reveals molecular patterns associated with distinct IGH translocations in multiple myeloma
Q30316573Gene expression profiling of porcine mammary epithelial cells after challenge with Escherichia coli and Staphylococcus aureus in vitro
Q28647160Gene expression studies of a human monocyte cell line identify dissimilarities between differently manufactured glatiramoids
Q30898776Gene network and pathway analysis of bovine mammary tissue challenged with Streptococcus uberis reveals induction of cell proliferation and inhibition of PPARgamma signaling as potential mechanism for the negative relationships between immune [...]
Q45089227Gene set enrichment analysis highlights different gene expression profiles in whole blood samples X-irradiated with low and high doses
Q35904413Gene transfer approaches in cancer immunotherapy.
Q38526092Gene-Environment Interactions in Asthma: Genetic and Epigenetic Effects
Q44495386Generation and functional characterization of a clonal murine periportal Kupffer cell line from H-2Kb -tsA58 mice.
Q47677806Generation of B-cell chronic lymphocytic leukemia (B-CLL)-reactive T-cell lines and clones from HLA class I-matched donors using modified B-CLL cells as stimulators: implications for adoptive immunotherapy
Q50976764Generation of stable orthogonal gradients of chemical concentration and substrate stiffness in a microfluidic device.
Q41928314Genetic Diversity of CD14 Promoter Gene Polymorphism (rs2569190) is Associated With Regulation of Malaria Parasitemia and Susceptibility to Plasmodium falciparum Infection
Q35114084Genetic control of susceptibility to bacterial infections in mouse models
Q24800607Genetic control of the innate immune response
Q35684737Genetic disruption of Fra-1 decreases susceptibility to endotoxin-induced acute lung injury and mortality in mice
Q37411483Genetic polymorphism in CD14 gene, a co-receptor of TLR4 associated with non-alcoholic fatty liver disease
Q37426328Genetic polymorphisms in vitamin D receptor, vitamin D-binding protein, Toll-like receptor 2, nitric oxide synthase 2, and interferon-gamma genes and its association with susceptibility to tuberculosis
Q33302872Genetic polymorphisms of TLR3 are associated with Nasopharyngeal carcinoma risk in Cantonese population
Q34993039Genetic regulation of host responses to Salmonella infection in mice.
Q54323953Genetic susceptibility to S. aureus mastitis in sheep: differential expression of mammary epithelial cells in response to live bacteria or supernatant.
Q26852514Genetic update on inflammatory factors in ulcerative colitis: Review of the current literature
Q48252436Genetic variation and activity of mouse Nod2, a susceptibility gene for Crohn's disease
Q34805799Genetics, cytokines and human infectious disease: lessons from weakly pathogenic mycobacteria and salmonellae
Q54472829Genome-wide transcriptional profiling of mononuclear phagocytes recruited to mouse lungs in response to alveolar challenge with the TLR2 agonist Pam3CSK4.
Q34992951Genomic profile of Toll-like receptor pathways in traumatically brain-injured mice: effect of exogenous progesterone
Q42144631Genomics in cardiovascular diseases: analysis of the importance of the toll-like receptor signaling pathway
Q48612880Ginkgolide B reduces neuronal cell apoptosis in the traumatic rat brain: possible involvement of toll-like receptor 4 and nuclear factor kappa B pathway
Q89921503Glaucoma: A Degenerative Optic Neuropathy Related to Neuroinflammation?
Q44051995Glucan stimulates human dermal fibroblast collagen biosynthesis through a nuclear factor-1 dependent mechanism
Q24804336Glucocorticoids synergize with IL-1beta to induce TLR2 expression via MAP Kinase Phosphatase-1-dependent dual Inhibition of MAPK JNK and p38 in epithelial cells
Q93222337Glucosamine improves survival in a mouse model of sepsis and attenuates sepsis-induced lung injury and inflammation
Q27021500Gram-negative marine bacteria: structural features of lipopolysaccharides and their relevance for economically important diseases
Q37345439Granulocyte-macrophage-colony-stimulating factor-dependent peritoneal macrophage responses determine survival in experimentally induced peritonitis and sepsis in mice.
Q46187873Greater expression of TLR2, TLR4, and IL6 due to negative energy balance is associated with lower expression of HLA-DRA and HLA-A in bovine blood neutrophils after intramammary mastitis challenge with Streptococcus uberis
Q26828771Growth and Development Symposium: Endotoxin, inflammation, and intestinal function in livestock
Q28209082Gut flora in health and disease
Q28085158Gut microbiota and non-alcoholic fatty liver disease
Q85013360Gymnasterkoreayne F inhibits osteoclast formation by suppressing NFATc1 and DC-STAMP expression
Q35970108HIV-1 Structural Proteins Serve as PAMPs for TLR2 Heterodimers Significantly Increasing Infection and Innate Immune Activation
Q35675014HMGB1 Promotes Systemic Lupus Erythematosus by Enhancing Macrophage Inflammatory Response.
Q45347650HMGB1 increases permeability of the endothelial cell monolayer via RAGE and Src family tyrosine kinase pathways
Q37573376HMGB1 translocation and release mediate cigarette smoke-induced pulmonary inflammation in mice through a TLR4/MyD88-dependent signaling pathway
Q35206504HSPA12B inhibits lipopolysaccharide-induced inflammatory response in human umbilical vein endothelial cells
Q35649459Heat shock factor 1 protects against lung mycoplasma pneumoniae infection in mice
Q36246603Heat shock proteins and scavenger receptors: role in adaptive immune responses
Q35517948Heightened uterine mammalian target of rapamycin complex 1 (mTORC1) signaling provokes preterm birth in mice
Q37465299Hematopoietic cell-specific deletion of toll-like receptor 4 ameliorates hepatic and adipose tissue insulin resistance in high-fat-fed mice
Q33782559Hepatitis B virus protein X-induced expression of the CXC chemokine IP-10 is mediated through activation of NF-kappaB and increases migration of leukocytes
Q34507250Hepatitis B virus: new therapeutic perspectives.
Q36703983High Mobility Group Box-1 mediates hyperoxia-induced impairment of Pseudomonas aeruginosa clearance and inflammatory lung injury in mice
Q36661053High-throughput secretomic analysis of single cells to assess functional cellular heterogeneity
Q37003162Histamine directly and synergistically with lipopolysaccharide stimulates cyclooxygenase-2 expression and prostaglandin I(2) and E(2) production in human coronary artery endothelial cells
Q44589817Histamine downregulates CD14 expression via H2 receptors on human monocytes
Q45067683Histamine induces Toll-like receptor 2 and 4 expression in endothelial cells and enhances sensitivity to Gram-positive and Gram-negative bacterial cell wall components
Q28366668Histamine regulates cytokine production in maturing dendritic cells, resulting in altered T cell polarization
Q83327045Honokiol rescues sepsis-associated acute lung injury and lethality via the inhibition of oxidative stress and inflammation
Q47823098Host factors impacting the innate response in humans to the candidate adjuvants RC529 and monophosphoryl lipid A.
Q34393835Host immune reactivity and antifungal chemotherapy: the power of being together.
Q34120673Host immune response to Salmonella enterica serovar Typhimurium infection in mice derived from wild strains
Q36761305Host innate immune response to Mycobacterium tuberculosis
Q37099709Host responses to wild-type and attenuated herpes simplex virus infection in the absence of Stat1
Q36528708How bacteria and their products provide clues to vaccine and adjuvant development
Q34572120How can immunology contribute to the control of tuberculosis?
Q34132896How do you see CG?
Q57029063How is the phagocyte lectin keyboard played? Master class lesson by Mycobacterium tuberculosis
Q36258209Hsa-mir-499 rs3746444 T/C Polymorphism is Associated with Increased Risk of Coronary Artery Disease in a Chinese Population.
Q58566613Human Metapneumovirus: Mechanisms and Molecular Targets Used by the Virus to Avoid the Immune System
Q33923795Human Nod1 confers responsiveness to bacterial lipopolysaccharides
Q33930537Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition
Q40763230Human Toll-like receptor 2 mediates induction of the antimicrobial peptide human beta-defensin 2 in response to bacterial lipoprotein
Q40210460Human conjunctival epithelial cells lack lipopolysaccharide responsiveness due to deficient expression of MD2 but respond after interferon-gamma priming or soluble MD2 supplementation
Q35965043Human genetics of intracellular infectious diseases: molecular and cellular immunity against mycobacteria and salmonellae
Q24537191Human gingival CD14(+) fibroblasts primed with gamma interferon increase production of interleukin-8 in response to lipopolysaccharide through up-regulation of membrane CD14 and MyD88 mRNA expression
Q33731760Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9.
Q44840259Human mannose-binding lectin and L-ficolin function as specific pattern recognition proteins in the lectin activation pathway of complement
Q39532133Human metapneumovirus glycoprotein G inhibits TLR4-dependent signaling in monocyte-derived dendritic cells
Q36712803Human umbilical cord blood-derived mast cells: a unique model for the study of neuro-immuno-endocrine interactions
Q34636380Hyaluronan as an immune regulator in human diseases.
Q44667832Hydration, ionic valence and cross-linking propensities of cations determine the stability of lipopolysaccharide (LPS) membranes
Q37768423Hyperoxia sensing: from molecular mechanisms to significance in disease
Q28575809Hypertensive rats are susceptible to TLR4-mediated signaling following exposure to combustion source particulate matter
Q57092220Hypoxia Exacerbates Inflammatory Acute Lung Injury the Toll-Like Receptor 4 Signaling Pathway
Q24798167IL-4 dependent alternatively-activated macrophages have a distinctive in vivo gene expression phenotype
Q44550687IL-4 receptor signaling is required for mannose receptor expression by macrophages recruited to granulomata but not resident cells in mice infected with Schistosoma mansoni
Q34208574IRAK1 rs3027898 C/A polymorphism is associated with risk of rheumatoid arthritis.
Q35585674Identification and immune functional characterization of pigeon TLR7.
Q40617489Identification of Evolutionarily Conserved Md1 Splice Variants That Regulate Innate Immunity through Differential Induction of NF-кB.
Q50104203Identification of a Sequence in Human Toll-like Receptor 5 Required for the Binding of Gram-negative Flagellin
Q39184705Identification of a novel collagen type І-binding protein from Streptococcus suis serotype 2.
Q44002721Identification of diacylated ureas as a novel family of fungus-specific leukocyte-activating pathogen-associated molecules
Q24290976Identification of hTLR10: a novel human Toll-like receptor preferentially expressed in immune cells
Q37421827Identification of human metapneumovirus-induced gene networks in airway epithelial cells by microarray analysis
Q36725283Identification of immune genes and proteins involved in the response of bovine mammary tissue to Staphylococcus aureus infection
Q33226572Identifying components of the NF-kappaB pathway in the beneficial Euprymna scolopes-Vibrio fischeri light organ symbiosis
Q36732464IkappaB kinase is an essential component of the Tpl2 signaling pathway
Q42800171IkappaB-zeta, a new anti-inflammatory nuclear protein induced by lipopolysaccharide, is a negative regulator for nuclear factor-kappaB.
Q36765878Imaging the role of toll-like receptor 4 on cell proliferation and inflammation after cerebral ischemia by positron emission tomography
Q53942754Immune gene discovery by expressed sequence tags generated from hemocytes of the bacteria-challenged oyster, Crassostrea gigas.
Q35982434Immune regulation and colitis: suppression of acute inflammation allows the development of chronic inflammatory bowel disease
Q84072297Immunoadjuvant efficacy of plasmids with multiple copies of a CpG motif coadministrated with avian influenza vaccine in chickens
Q38181015Immunobiology of critical pediatric asthma
Q34653776Immunochemoradiotherapy for patients with oral squamous cell carcinoma: augmentation of OK-432-induced helper T cell 1 response by 5-FU and X-ray irradiation
Q55435478Immunohistochemical and mRNA expression of RANK, RANKL, OPG, TLR2 and MyD88 during apical periodontitis progression in mice.
Q51323708Immunological responses after immunisation of mice with microparticles containing antigen and single stranded RNA (polyuridylic acid).
Q33862003Immunological stimuli change expression of genes and neutrophil function in fathead minnow Pimephales promelas Rafinesque.
Q92345026Immunology of Adenoviral Vectors in Cancer Therapy
Q34116840Immunology of parasitic helminth infections
Q50886718Immunomodulatory Activity of Octenyl Succinic Anhydride Modified Porang (Amorphophallus oncophyllus) Glucomannan on Mouse Macrophage-Like J774.1 Cells and Mouse Primary Peritoneal Macrophages.
Q40249339Immunomodulatory effects of Pseudomonas aeruginosa quorum sensing small molecule probes on mammalian macrophages
Q38550639Immunopathogenesis of hepatitis B persistent infection: implications for immunotherapeutic strategies
Q34635889Immunoregulation of CNS autoimmunity by helminth and mycobacterial infections.
Q35574087Immunostimulatory Oligonucleotides: Ready for Immunotherapy Prime Time!
Q35813718Immunostimulatory activity of snake fruit peel extract on murine macrophage-like J774.1 cells
Q48335054Immunostimulatory effect of aqueous extract of Coriandrum sativum L. seed on macrophages.
Q39022571Immunostimulatory effect of dried bonito extract on mouse macrophage cell lines and mouse primary peritoneal macrophages.
Q38776941Immunostimulatory effect of spinach aqueous extract on mouse macrophage-like J774.1 cells and mouse primary peritoneal macrophages
Q35730784Immunotherapeutic uses of CpG oligodeoxynucleotides
Q34547881Immunotherapy of sepsis
Q48694325Impact of TLR5 rs5744174 on stroke risk, gene expression and on inflammatory cytokines, and lipid levels in stroke patients
Q87634045Impact of Toll-like receptor 4 deficiency on cerebrocardiac syndrome
Q37809892Impact of Toll-like receptor 4 polymorphisms on risk of cancer
Q45090402Impact of class A, B and C CpG-oligodeoxynucleotides on in vitro activation of innate immune cells in human immunodeficiency virus-1 infected individuals.
Q37060644Impaired clearance of apoptotic cells leads to HMGB1 release in the bone marrow of patients with myelodysplastic syndromes and induces TLR4-mediated cytokine production.
Q35740865Implications of microbiota and bile acid in liver injury and regeneration
Q36531831Improved Survival and Neurological Outcomes after Cardiopulmonary Resuscitation in Toll-like Receptor 4-mutant Mice
Q35722875In Ovo Administration of Silver Nanoparticles and/or Amino Acids Influence Metabolism and Immune Gene Expression in Chicken Embryos
Q39537395In Silico and In Vitro Studies of Truncated Forms of Flagellin (FliC) of Enteroaggregative Escherichia coli (EAEC).
Q38132218In vitro drug metabolism testing using blood-monocyte derivatives.
Q37667442In vitro immunogenic and immunostimulatory effects of zwitterionized 23-valent pneumococcal polysaccharide vaccine compared with nonzwitterionized vaccine
Q42181218In vitro immunomodulatory activity of oxymatrine on Toll-like receptor 9 signal pathway in chronic hepatitis B.
Q42452130Increased Levels of LPS-Binding Protein in Bovine Blood and Milk Following Bacterial Lipopolysaccharide Challenge
Q54622727Increased expression of Toll like receptor 4 on peripheral-blood mononuclear cells in patients with coronary arteriosclerosis disease.
Q86560479Increased expression of interleukin-8 is an independent indicator of poor prognosis in clear-cell renal cell carcinoma
Q50774855Increased levels of circulating soluble CD14 but not CD83 in infants are associated with early intestinal colonization with Staphylococcus aureus.
Q54531853Increased plasma concentration of surfactant protein D in chronic periodontitis independent of SFTPD genotype: potential role as a biomarker.
Q36429729Increased toll-like receptor 2 expression in peptidoglycan-treated blood monocytes is associated with insulin resistance in patients with nondiabetic rheumatoid arthritis
Q35988797Induction of antigen cross-presentation by Toll-like receptors
Q54447032Induction of cyclooxygenase-2 by heat shock protein 60 in macrophages and endothelial cells.
Q50045140Induction of cytokine formation by human intestinal bacteria in gut epithelial cell lines
Q37019629Induction of inflammatory and immune responses by HMGB1-nucleosome complexes: implications for the pathogenesis of SLE
Q30732295Induction of the cyclic nucleotide phosphodiesterase PDE4B is essential for LPS-activated TNF-alpha responses
Q40562231Induction of tolerance by Porphyromonas gingivalis on APCS: a mechanism implicated in periodontal infection
Q37159157Inductive and suppressive networks regulate TLR9-dependent gene expression in vivo
Q90401101Inflammation Induced by Platelet-Activating Viperid Snake Venoms: Perspectives on Thromboinflammation
Q37544889Inflammatory disease processes and interactions with nutrition
Q46935942Influence of the gut microbiota on blood acute-phase proteins
Q23919666Inhibition of nuclear factor kB by phenolic antioxidants: interplay between antioxidant signaling and inflammatory cytokine expression
Q34152480Inhibition of p38 MAPK by glucocorticoids via induction of MAPK phosphatase-1 enhances nontypeable Haemophilus influenzae-induced expression of toll-like receptor 2.
Q37322917Inhibition of poly (adenosine diphosphate-ribose) polymerase attenuates lung-kidney crosstalk induced by intratracheal lipopolysaccharide instillation in rats
Q36025944Inhibition of the NF-κB signaling pathway by the curcumin analog, 3,5-Bis(2-pyridinylmethylidene)-4-piperidone (EF31): anti-inflammatory and anti-cancer properties.
Q90400543Inhibitory Effects of Aucklandia lappa Decne. Extract on Inflammatory and Oxidative Responses in LPS-Treated Macrophages
Q87816969Inhibitory effect of selected medicinal plants on the release of pro-inflammatory cytokines in lipopolysaccharide-stimulated human peripheral blood mononuclear cells
Q38753842Inhibitory effects on the production of inflammatory mediators and reactive oxygen species by Mori folium in lipopolysaccharide-stimulated macrophages and zebrafish
Q36112137Innate and adaptive immune responses during acute M. tuberculosis infection in adult household contacts in Kampala, Uganda
Q37411862Innate immune reactivity of the liver in rats fed a choline-deficient L-amino-acid-defined diet
Q37878291Innate immune recognition of Mycobacterium tuberculosis
Q35970287Innate immune responses during infection
Q37610450Innate immune signaling pathways in animals: beyond reductionism
Q39072247Innate immunity against Legionella pneumophila during pulmonary infections in mice
Q37419472Innate immunity and heat shock response in islet transplantation
Q48050484Innate immunity and the evolution of resistance to an emerging infectious disease in a wild bird
Q38035032Innate immunity and the regulation and mobilization of keratinocyte stem cells: are the old players playing a new game?
Q30320786Innate immunity in plants and animals: emerging parallels between the recognition of general elicitors and pathogen-associated molecular patterns
Q44661444Innate immunity stimulates permeability barrier homeostasis
Q37263026Innate immunity to Paracoccidioides brasiliensis infection
Q27014127Innate immunity, decidual cells, and preeclampsia
Q36889564Innate immunogenetics: a tool for exploring new frontiers of host defence
Q26830891Innocent until proven guilty: mechanisms and roles of Streptococcus-Candida interactions in oral health and disease
Q36394688Instigation of endothelial Nlrp3 inflammasome by adipokine visfatin promotes inter-endothelial junction disruption: role of HMGB1.
Q59136363Integrating Immunology and Microfluidics for Single Immune Cell Analysis
Q40686330Integrin-nucleated Toll-like receptor (TLR) dimerization reveals subcellular targeting of TLRs and distinct mechanisms of TLR4 activation and signaling
Q35014476Interaction of Pattern Recognition Receptors with Mycobacterium Tuberculosis
Q36783810Interaction of lipopolysaccharide and phospholipid in mixed membranes: solid-state 31P-NMR spectroscopic and microscopic investigations
Q40718875Interaction of matrix with integrin receptors is required for optimal LPS-induced MAP kinase activation.
Q83350762Interference with nuclear factor kappa B and c-Jun NH2-terminal kinase signaling by TRAF6C small interfering RNA inhibits myeloma cell proliferation and enhances apoptosis
Q42079485Interferon-alpha and interleukin-12 are induced differentially by Toll-like receptor 7 ligands in human blood dendritic cell subsets
Q28207081Interferon-γ: an overview of signals, mechanisms and functions
Q34248184Internalization and phagosome escape required for Francisella to induce human monocyte IL-1beta processing and release
Q36324962Interplay between interferon and other cytokine systems in bone metabolism
Q36209709Intestinal macrophages: unique effector cells of the innate immune system
Q39333880Intracellular Staphylococcus aureus-induced NF-κB activation and proinflammatory responses of P815 cells are mediated by NOD2.
Q40545709Intracellular signaling and cytokine induction upon interactions of Porphyromonas gingivalis fimbriae with pattern-recognition receptors
Q36244190Intraperitoneal administration of poly(I:C) with polyethylenimine leads to significant antitumor immunity against murine ovarian tumors
Q40628602Intratumor CpG-Oligodeoxynucleotide Injection Induces Protective Antitumor T Cell Immunity
Q34727317Introduction: innate recognition of bacteria and protozoan parasites
Q35042912Introduction: rationale for using drotrecogin alfa (activated) in patients with severe sepsis
Q34416504Inulin and oligofructose: impact on intestinal diseases and disorders
Q56610443Invited review: Bacterial lipopolysaccharides and innate immunity
Q40633161Involvement of Leucine Residues at Positions 107, 112, and 115 in a Leucine-Rich Repeat Motif of Human Toll-Like Receptor 2 in the Recognition of Diacylated Lipoproteins and Lipopeptides and Staphylococcus aureus Peptidoglycans
Q24299651Involvement of TIRAP/MAL in signaling for the activation of interferon regulatory factor 3 by lipopolysaccharide
Q54601910Involvement of mitogen-activated protein kinase activation in cyclooxygenase-2 and transforming growth factor-β production in alveolar macrophage from chronic bronchitis rats.
Q34360749Is the class A macrophage scavenger receptor (SR-A) multifunctional? - The mouse's tale
Q34537221Isoflavones inhibit poly(I:C)-induced serum, brain, and skin inflammatory mediators - relevance to chronic fatigue syndrome
Q55231531Isosteviol sodium injection improves outcomes by modulating TLRs/NF-κB-dependent inflammatory responses following experimental traumatic brain injury in rats.
Q35409103KIM-1-mediated phagocytosis reduces acute injury to the kidney
Q34974449KOBAS server: a web-based platform for automated annotation and pathway identification
Q33993559Kdo2-Lipid A of Escherichia coli, a defined endotoxin that activates macrophages via TLR-4.
Q37227885Keratin 8 limits TLR-triggered inflammatory responses through inhibiting TRAF6 polyubiquitination
Q37401084Key role of macrophages in the pathogenesis of CD18 hypomorphic murine model of psoriasis
Q33676038Klebsiella pneumoniae capsule polysaccharide impedes the expression of beta-defensins by airway epithelial cells
Q39915508Klebsiella pneumoniae increases the levels of Toll-like receptors 2 and 4 in human airway epithelial cells
Q47392369LPS induces IL-8 expression through TLR4, MyD88, NF-kappaB and MAPK pathways in human dental pulp stem cells
Q34189313LPS induction of gene expression in human monocytes
Q41821136LPS-induced IL-6, IL-8, VCAM-1, and ICAM-1 expression in human lymphatic endothelium
Q36240643LPS-induced modules of co-expressed genes in equine peripheral blood mononuclear cells
Q52994753Lack of antigen-specific Th1 response alters granuloma formation and composition in Schistosoma mansoni-infected MyD88-/- mice.
Q45039592Lack of association of the 3'-UTR polymorphism in the NFKBIA gene with Crohn's disease in an Israeli cohort
Q44545274Lactobacillus brevis G-101 ameliorates colitis in mice by inhibiting NF-κB, MAPK and AKT pathways and by polarizing M1 macrophages to M2-like macrophages
Q33928149Lactobacillus saerimneri and Lactobacillus ruminis: novel human-derived probiotic strains with immunomodulatory activities
Q35586928Late repression of NF-κB activity by invasive but not non-invasive meningococcal isolates is required to display apoptosis of epithelial cells
Q40701954Leishmania major activates IL-1 alpha expression in macrophages through a MyD88-dependent pathway
Q41753270Leonurine exerts anti-inflammatory effect by regulating inflammatory signaling pathways and cytokines in LPS-induced mouse mastitis
Q33940165Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism.
Q35080370Lignin-rich enzyme lignin (LREL), a cellulase-treated lignin-carbohydrate derived from plants, activates myeloid dendritic cells via Toll-like receptor 4 (TLR4)
Q34114211Ligusticum wallichii Extract Inhibited the Expression of IL-1β after AMI in Rats
Q91831291Linarin down-regulates phagocytosis, pro-inflammatory cytokine production, and activation marker expression in RAW264.7 macrophages
Q30163861Lipid trafficking controls endotoxin acylation in outer membranes of Escherichia coli
Q48402759Lipopolysaccharide (LPS)-stimulated iNOS Induction Is Increased by Glucosamine under Normal Glucose Conditions but Is Inhibited by Glucosamine under High Glucose Conditions in Macrophage Cells
Q38758056Lipopolysaccharide Structure and Biosynthesis in Helicobacter pylori
Q40772877Lipopolysaccharide and CpG DNA synergize for tumor necrosis factor-alpha production through activation of NF-kappaB.
Q39656127Lipopolysaccharide desensitization of macrophages provides protection against Yersinia enterocolitica-induced apoptosis
Q24650970Lipopolysaccharide endotoxins
Q24306498Lipopolysaccharide from enterohemorrhagic Escherichia coli binds to platelets through TLR4 and CD62 and is detected on circulating platelets in patients with hemolytic uremic syndrome
Q48246662Lipopolysaccharide inhibits hepatic gluconeogenesis in rats: The role of immune cells
Q24290990Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex. transfer from CD14 to TLR4 and MD-2
Q40690745Lipopolysaccharide modulation of normal enterocyte turnover by toll-like receptors is mediated by endogenously produced tumour necrosis factor alpha
Q48708314Lipopolysaccharide-binding protein modulates hepatic damage and the inflammatory response after hemorrhagic shock and resuscitation
Q37084615Lipopolysaccharides from distinct pathogens induce different classes of immune responses in vivo
Q45223612Liposomal amphotericin B activates antifungal resistance with reduced toxicity by diverting Toll-like receptor signalling from TLR-2 to TLR-4.
Q40063735Lipoteichoic acid is important in innate immune responses to gram-positive bacteria.
Q44830110Lipoteichoic acid-stimulated p42/p44 MAPK activation via Toll-like receptor 2 in tracheal smooth muscle cells
Q39654596Lipoteichoic acids from Lactobacillus johnsonii strain La1 and Lactobacillus acidophilus strain La10 antagonize the responsiveness of human intestinal epithelial HT29 cells to lipopolysaccharide and gram-negative bacteria
Q35040127Liver in sepsis and systemic inflammatory response syndrome
Q34207769Localization of type I interferon receptor limits interferon-induced TLR3 in epithelial cells
Q42128315Long-lasting effect of infant rats endotoxemia on heat shock protein 60 in the pancreatic acinar cells: involvement of toll-like receptor 4
Q37067662Low-density lipoprotein receptors regulate microglial inflammation through c-Jun N-terminal kinase
Q40058386Luteolin suppresses inflammation-associated gene expression by blocking NF-kappaB and AP-1 activation pathway in mouse alveolar macrophages
Q28511286MAIL, a novel nuclear I kappa B protein that potentiates LPS-induced IL-6 production
Q52594626MAP kinase signalling cascade in Arabidopsis innate immunity.
Q35850011MFHAS1 Is Associated with Sepsis and Stimulates TLR2/NF-κB Signaling Pathway Following Negative Regulation
Q36520311Macrophage SR-BI regulates LPS-induced pro-inflammatory signaling in mice and isolated macrophages
Q90234765Macrophage Signaling Pathways in Pulmonary Nontuberculous Mycobacteria Infections
Q34628945Macrophage defences against respiratory tract infections.
Q34727502Macrophage signaling by glycosylphosphatidylinositol-anchored mucin-like glycoproteins derived from Trypanosoma cruzi trypomastigotes.
Q54473983Macrophage tumor necrosis factor-alpha induces epithelial expression of granulocyte-macrophage colony-stimulating factor: impact on alveolar epithelial repair.
Q40774148Macrophage-oriented cytotoxic activity of novel triterpene saponins extracted from roots of Securidaca inappendiculata
Q24291852Macrophages exposed continuously to lipopolysaccharide and other agonists that act via toll-like receptors exhibit a sustained and additive activation state
Q28473589Macrophages recognize size and shape of their targets
Q78699977Mammalian Toll-like receptors
Q33816520Mammary gene expression profiles during an intramammary challenge reveal potential mechanisms linking negative energy balance with impaired immune response
Q45150408Marantodes pumilum (Blume) Kuntze Inhibited Secretion of Lipopolysaccharide- and Monosodium Urate Crystal-stimulated Cytokines and Plasma Prostaglandin E2.
Q83029950Mast cells and inflammation
Q35541889Mastitis increases mammary mRNA abundance of beta-defensin 5, toll-like-receptor 2 (TLR2), and TLR4 but not TLR9 in cattle.
Q30544940Maternal immune activation promotes hippocampal kindling epileptogenesis in mice
Q33864957Maternal smoking in pregnancy: do the effects on innate (toll-like receptor) function have implications for subsequent allergic disease?
Q52604201Maternal transfer of strain-specific immunity in an invertebrate.
Q40962051Mathematical Model of Innate and Adaptive Immunity of Sepsis: A Modeling and Simulation Study of Infectious Disease
Q39686934Mechanical ventilation modulates TLR4 and IRAK-3 in a non-infectious, ventilator-induced lung injury model.
Q84070132Mechanical ventilation modulates Toll-like receptor signaling pathway in a sepsis-induced lung injury model
Q34497596Mechanism and inhibition of LpxC: an essential zinc-dependent deacetylase of bacterial lipid A synthesis.
Q34585655Mechanisms of bacterial pathogenicity
Q34233176Mechanisms of decreased intestinal epithelial proliferation and increased apoptosis in murine acute lung injury
Q34449816Mechanisms of fever production and lysis: lessons from experimental LPS fever
Q34589977Mechanisms of tissue injury in sepsis: contrasts between gram positive and gram negative infection
Q36232209Mechanisms of triglyceride accumulation in activated macrophages
Q84969771Medicinal Chemistry of siRNA Delivery
Q28552464Membrane Insertion for the Detection of Lipopolysaccharides: Exploring the Dynamics of Amphiphile-in-Lipid Assays
Q37296981Metastatic-promoting effects of LPS: sexual dimorphism and mediation by catecholamines and prostaglandins
Q37866669MicroRNA involvement in immune activation during heart failure
Q38823315MicroRNA regulation of macrophages in human pathologies
Q90221850MicroRNA-1294 inhibited oral squamous cell carcinoma growth by targeting c-Myc
Q35883959MicroRNA-induced negative regulation of TLR-5 in grass carp, Ctenopharyngodon idella
Q34261814Microarray analysis of the effect of Streptococcus equi subsp. zooepidemicus M-like protein in infecting porcine pulmonary alveolar macrophage
Q40014245Microarray analysis reveals induction of lipoprotein genes in mucoid Pseudomonas aeruginosa: implications for inflammation in cystic fibrosis.
Q34154041Microbial glycan microarrays define key features of host-microbial interactions
Q34006644Micrococcus luteus teichuronic acids activate human and murine monocytic cells in a CD14- and toll-like receptor 4-dependent manner
Q34580887Models of white matter injury: comparison of infectious, hypoxic-ischemic, and excitotoxic insults
Q79750884Modification of TLR-induced activation of human dendritic cells by type I IFN: synergistic interaction with TLR4 but not TLR3 agonists
Q64936452Modifying clonal selection theory with a probabilistic cell.
Q35737359Modulating LPS signal transduction at the LPS receptor complex with synthetic Lipid A analogues
Q40453387Modulating endotoxin activity by combinatorial bioengineering of meningococcal lipopolysaccharide.
Q28077242Modulation of Immunoregulatory Properties of Mesenchymal Stromal Cells by Toll-Like Receptors: Potential Applications on GVHD
Q48348468Modulation of Innate Immunity by lignin-Carbohydrate, a Novel TLR4 Ligand, Results in Augmentation of Mucosal IgA and Systemic IgG Production.
Q39663303Modulation of cytosolic Ca(2+) concentration in airway epithelial cells by Pseudomonas aeruginosa
Q50060087Modulation of toll-like receptor signaling by antimicrobial peptides
Q39693467Moesin-induced signaling in response to lipopolysaccharide in macrophages
Q35119884Molecular Mechanisms of B Cell Antigen Receptor Trafficking
Q45857334Molecular evolution of daphnia immunity genes: polymorphism in a gram-negative binding protein gene and an alpha-2-macroglobulin gene
Q40580696Molecular immunology profiles of monkeys following xenografting with the islets and heart of α-1,3-galactosyltransferase knockout pigs
Q78625788Molecular sensing of bacteria in plants. The highly conserved RNA-binding motif RNP-1 of bacterial cold shock proteins is recognized as an elicitor signal in tobacco
Q36294297Molecular targets related to inflammation and insulin resistance and potential interventions
Q90776144Molybdenum bupropion combined neurotoxicity in rats
Q37869249Monocytes heterozygous for the Asp299Gly and Thr399Ile mutations in the Toll-like receptor 4 gene show no deficit in lipopolysaccharide signalling.
Q35176410Mouse mammary tumor virus and the immune system
Q27491017Mouse models for human otitis media
Q26830597Mucins and toll-like receptors: kith and kin in infection and cancer
Q35192183Mucosal adjuvants and anti-infection and anti-immunopathology vaccines based on cholera toxin, cholera toxin B subunit and CpG DNA.
Q46448145Mutational analysis of membrane and soluble forms of human MD-2.
Q28345340Mutations in the Drosophila dTAK1 gene reveal a conserved function for MAPKKKs in the control of rel/NF-kappaB-dependent innate immune responses
Q37286394MyD88 controls human metapneumovirus-induced pulmonary immune responses and disease pathogenesis
Q40630648MyD88 is essential for clearance of Leishmania major: possible role for lipophosphoglycan and Toll‐like receptor 2 signaling
Q54766646Mycobacterial infection in TLR2 and TLR6 knockout mice.
Q24337789Mycobacterium bovis BCG cell wall and lipopolysaccharide induce a novel gene, BIGM103, encoding a 7-TM protein: identification of a new protein family having Zn-transporter and Zn-metalloprotease signatures
Q24290992Mycobacterium bovis Bacillus Calmette-Guerin and its cell wall complex induce a novel lysosomal membrane protein, SIMPLE, that bridges the missing link between lipopolysaccharide and p53-inducible gene, LITAF(PIG7), and estrogen-inducible gene, EET-1
Q48124372Mycobacterium tuberculosis Molecular Determinants of Infection, Survival Strategies, and Vulnerable Targets
Q36155020Mycobacterium tuberculosis Rv2882c Protein Induces Activation of Macrophages through TLR4 and Exhibits Vaccine Potential
Q33811658Mycobacterium tuberculosis, macrophages, and the innate immune response: does common variation matter?
Q34658552Myeloid differentiation (MyD) primary response genes in hematopoiesis
Q28215099Myeloid differentiation (MyD)/growth arrest DNA damage (GADD) genes in tumor suppression, immunity and inflammation
Q34518568Myristoylation negative msbB-mutants of probiotic E. coli Nissle 1917 retain tumor specific colonization properties but show less side effects in immunocompetent mice.
Q43910356N-(3-oxo-acyl)homoserine lactones signal cell activation through a mechanism distinct from the canonical pathogen-associated molecular pattern recognition receptor pathways.
Q33946526N-linked glycosylation at Asn3 and the positively charged residues within the amino-terminal domain of the c1 inhibitor are required for interaction of the C1 Inhibitor with Salmonella enterica serovar typhimurium lipopolysaccharide and lipid A.
Q46024987NADPH oxidase 4 modulates hepatic responses to lipopolysaccharide mediated by Toll-like receptor-4.
Q40488596NF-kappaB- and C/EBPbeta-driven interleukin-1beta gene expression and PAK1-mediated caspase-1 activation play essential roles in interleukin-1beta release from Helicobacter pylori lipopolysaccharide-stimulated macrophages
Q28187604NF-kappaB1/p105 regulates lipopolysaccharide-stimulated MAP kinase signaling by governing the stability and function of the Tpl2 kinase
Q38044173NOD2 signaling and role in pathogenic mycobacterium recognition, infection and immunity
Q64077595Nano-mediated delivery of double-stranded RNA for gene therapy of glioblastoma multiforme
Q92256337Nanomaterials for Biosensing Lipopolysaccharide
Q35035726Natural killer cell activation receptors in innate immunity to infection
Q38127782Natural resolution of inflammation
Q35630589Necrotroph attacks on plants: wanton destruction or covert extortion?
Q40501729Negative regulation of JNK signaling by the tumor suppressor CYLD.
Q36342098Neuropeptide PACAP in mouse liver ischemia and reperfusion injury: immunomodulation by the cAMP-PKA pathway
Q58905565New Aspects in Immunopathology of Mycobacterium tuberculosis
Q35159086New approaches in vaccine development
Q35161743New aspects of IFN-alpha/beta signalling in immunity, oncogenesis and bone metabolism
Q38166953New paradigms in inflammatory signaling in vascular endothelial cells
Q40683593Nitric oxide and resolution of inflammation.
Q35963562Nitric oxide contributes to induction of innate immune responses to gram-negative bacteria in Drosophila.
Q75196844Nitric oxide release by hemocytes of the mussel Mytilus galloprovincialis Lmk was provoked by interleukin-2 but not by lipopolysaccharide
Q39788177Nitric oxide synthase 1 and cyclooxygenase-2 enzymes are targets of muscarinic activation in normal and inflamed NIH3T3 cells
Q82700322No evidence for association between the interferon regulatory factor 1 (IRF1) gene and clinical tuberculosis
Q46057413Non-invasive monitoring of redox status in mice with dextran sodium sulphate-induced colitis
Q42556466Non-synonymous genetic variation in exonic regions of canine Toll-like receptors
Q39403634Norkurarinol inhibits toll-like receptor 3 (TLR3)-mediated pro-inflammatory signaling pathway and rotavirus replication
Q57174623Normal Development of the Gut-Associated Lymphoid Tissue Except Peyer's Patch in MyD88-Deficient Mice
Q27477518Novel Role of Toll-Like Receptor 3 in Hepatitis C-Associated Glomerulonephritis
Q37812128Novel adjuvants and delivery systems for enhancing immune responses induced by immunogens
Q37367885Novel pharmacologic approaches to the management of sepsis: targeting the host inflammatory response
Q34272259Now I know my CpGs
Q34333586Nuclear factor kappa-B and the heart
Q34429415Nucleotide oligomerization domain 2 (Nod2) is not involved in the pattern recognition of Candida albicans
Q26774779Obesity-Driven Gut Microbiota Inflammatory Pathways to Metabolic Syndrome
Q46841537Obstructive jaundice increases sensitivity to lipopolysaccharide via TLR4 upregulation: possible involvement in gut-derived hepatocyte growth factor-protection of hepatocytes
Q74499741Of mice and men: species variations of Toll-like receptor expression
Q36376473Oligosaccharides of Hyaluronan activate dendritic cells via toll-like receptor 4.
Q46751975On the role and fate of LPS-dephosphorylating activity in the rat liver
Q38360283Opposing roles of activator protein-1 and CCAAT/enhancer binding protein beta in the regulation of inducible granulysin gene expression in a human monocytic cell line, THP-1.
Q39871614Oral administration of poly-gamma-glutamate induces TLR4- and dendritic cell-dependent antitumor effect
Q35963446Oral inflammatory diseases and systemic inflammation: role of the macrophage.
Q34195537Oral-derived bacterial flora defends its domain by recognizing and killing intruders--a molecular analysis using Escherichia coli as a model intestinal bacterium
Q33385144Organism-specific platelet response and factors affecting survival in thrombocytopenic very low birth weight babies with sepsis
Q34191665Origin of lipid A species modified with 4-amino-4-deoxy-L-arabinose in polymyxin-resistant mutants of Escherichia coli. An aminotransferase (ArnB) that generates UDP-4-deoxyl-L-arabinose
Q41984008Orostachys japonicus Inhibits Expression of the TLR4, NOD2, iNOS, and COX-2 Genes in LPS-Stimulated Human PMA-Differentiated THP-1 Cells by Inhibiting NF-κB and MAPK Activation.
Q53509790Ostericum koreanum Reduces LPS-Induced Bone Loss Through Inhibition of Osteoclastogenesis.
Q35874571Outer membrane protein A (OmpA) of Shigella flexneri 2a links innate and adaptive immunity in a TLR2-dependent manner and involvement of IL-12 and nitric oxide
Q42581877Outer membrane protein A of Escherichia coli O157:H7 stimulates dendritic cell activation.
Q34659235Over-expression of TLR4-CD14, pro-inflammatory cytokines, metabolic markers and NEFAs in obese non-diabetic Mexicans
Q34101511Oxidative decarboxylation of UDP-glucuronic acid in extracts of polymyxin-resistant Escherichia coli. Origin of lipid a species modified with 4-amino-4-deoxy-L-arabinose
Q48681818Oxidative stress and cellular pathways of asthma and inflammation: Therapeutic strategies and pharmacological targets
Q34095777Oxygen-glucose deprivation of neurons transfected with toll-like receptor 3-siRNA: Determination of an optimal transfection sequence.
Q83053583Oxymatrine reduces neuronal cell apoptosis by inhibiting Toll-like receptor 4/nuclear factor kappa-B-dependent inflammatory responses in traumatic rat brain injury
Q90164388PKCδ Mediates NF-κB Inflammatory Response and Downregulates SIRT1 Expression in Liver Fibrosis
Q27489023PR3-ANCA in Wegener's granulomatosis prime human mononuclear cells for enhanced activation via TLRs and NOD1/2
Q28588062PTX3 function as an opsonin for the dectin-1-dependent internalization of zymosan by macrophages
Q50075097Pancreatic cancer and associated exosomes
Q36032639Pathogen-host interactions in Pseudomonas aeruginosa pneumonia
Q34449857Pathogenesis and therapeutic approaches for non-alcoholic fatty liver disease
Q42236324Pattern recognition receptors and cytokines in Mycobacterium tuberculosis infection--the double-edged sword?
Q30320728Pep-13, a plant defense-inducing pathogen-associated pattern from Phytophthora transglutaminases.
Q38668711Peptide Arrays for Kinome Analysis of Livestock Species
Q33194302Peptidoglycan Recognition Proteins Involved in 1,3-β-D-Glucan-dependent Prophenoloxidase Activation System of Insect
Q54343497Peptidoglycan and lipopolysaccharide synergistically enhance bone resorption and osteoclastogenesis.
Q39644376Peptidoglycan induces interleukin‐6 expression through the TLR2 receptor, JNK, c‐Jun, and AP‐1 pathways in microglia
Q24291457Peptidoglycan recognition proteins: a novel family of four human innate immunity pattern recognition molecules
Q46311445Perinatal periodontal disease reduces social behavior in male offspring.
Q28484797Periplasmic cleavage and modification of the 1-phosphate group of Helicobacter pylori lipid A
Q28365786Peroxisome proliferator-activated receptor-gamma haploinsufficiency enhances B cell proliferative responses and exacerbates experimentally induced arthritis
Q37619071Pestiviruses: how to outmaneuver your hosts.
Q44871413Phagocytosis and the inflammatory response
Q34733255Phagocytosis by invertebrate hemocytes: causes of individual variation in Panorpa vulgaris scorpionflies
Q50853469Phenotypic differences in leucocyte populations among healthy preterm and full-term newborns.
Q73914538Phorbol esters induce translocation of the nPKC p105 to membrane in mussel hemocytes
Q40636829Phosphatidic acid regulates systemic inflammatory responses by modulating the Akt-mammalian target of rapamycin-p70 S6 kinase 1 pathway
Q37106060Phosphodiesterase 4 inhibition but not beta-adrenergic stimulation suppresses tumor necrosis factor-alpha release in peripheral blood mononuclear cells in septic shock
Q37106913Physical and functional interactions between Drosophila TRAF2 and Pelle kinase contribute to Dorsal activation.
Q44804213Physiopathology of severe sepsis
Q57057886Phytochemicals as a potential source for TNF-α inhibitors
Q34646875Pig immune response to general stimulus and to porcine reproductive and respiratory syndrome virus infection: a meta-analysis approach
Q28207107Plant pathogens and integrated defence responses to infection
Q35981238Plasmacytoid dendritic cell precursors/type I interferon-producing cells sense viral infection by Toll-like receptor (TLR) 7 and TLR9.
Q37769441Plasmacytoid dendritic cells in antiviral immunity and autoimmunity
Q28215261Platelet-activating factor receptor and ADAM10 mediate responses to Staphylococcus aureus in epithelial cells
Q40286909Platonin attenuates LPS-induced CAT-2 and CAT-2B induction in stimulated murine macrophages
Q36249205Pleurotus giganteus (Berk. Karun & Hyde), the giant oyster mushroom inhibits NO production in LPS/H2O2 stimulated RAW 264.7 cells via STAT 3 and COX-2 pathways
Q35206508Poly (I:C) therapy decreases cerebral ischaemia/reperfusion injury via TLR3-mediated prevention of Fas/FADD interaction
Q57253880Polymorphisms in Toll-Like Receptor 4 Are Not Associated with Asthma or Atopy-related Phenotypes
Q73425582Polymorphisms in lymphotoxin alpha and CD14 genes influence TNFalpha production induced by Gram-positive and Gram-negative bacteria
Q28570130Polyunsaturated fatty acid supplementation alters proinflammatory gene expression and reduces the incidence of necrotizing enterocolitis in a neonatal rat model
Q38589507Possible evidence of systemic lupus erythematosus and periodontal disease association mediated by Toll-like receptors 2 and 4.
Q44031567Possible participation of intracellular platelet-activating factor in NF-kappaB activation in rat peritoneal macrophages.
Q41874084Postconditioning improvement effects of ulinastatin on brain injury following cardiopulmonary resuscitation
Q39700445Potentiation of protein kinase C zeta activity by 15-deoxy-delta(12,14)-prostaglandin J(2) induces an imbalance between mitogen-activated protein kinases and NF-kappa B that promotes apoptosis in macrophages.
Q40551790Prebiotics in infant milk formulas: new perspectives
Q33862295Preclinical Studies and Translational Applications of Intracerebral Hemorrhage.
Q38011249Preclinical development of TLR ligands as drugs for the treatment of chronic viral infections.
Q36667000Preclinical investigations reveal the broad-spectrum neutralizing activity of peptide Pep19-2.5 on bacterial pathogenicity factors
Q34374495Predisposing factors in the spondyloarthropathies: new insights into the role of HLA-B27.
Q46154692Prenatal exposure to TAK242 affects the childhood autism in offspring in animal models of autism spectrum disorder
Q83806435Preparation and identification of the lipopolysaccharide binding protein mimic epitope peptide vaccine that prevents endotoxin-induced acute lung injury in mice
Q55470658Presentation matters: Impact of association of amphiphilic LPS with serum carrier proteins on innate immune signaling.
Q42481158Primed monocytes: putative culprits of chronic low-grade inflammation and impaired innate immune responses in patients on hemodialysis
Q54296064Pro-inflammatory properties of shark cartilage supplement.
Q34665535Probiotics and immune response.
Q41975206Probiotics inhibit TNF-alpha-induced interleukin-8 secretion of HT29 cells.
Q37013252Production of interleukin-27 by human neutrophils regulates their function during bacterial infection
Q35678201Profiles of carbohydrate ligands associated with adsorbed proteins on self-assembled monolayers of defined chemistries
Q37418300Profiling CD antigens on leukaemias with an antibody microarray
Q37454121Profiling carbohydrate-receptor interaction with recombinant innate immunity receptor-Fc fusion proteins
Q36370942Progress in understanding postnatal immune dysregulation in allergic disease
Q30847857Prolonged exposure to bacterial toxins downregulated expression of toll-like receptors in mesenchymal stromal cell-derived osteoprogenitors.
Q36240300Propentofylline Prevents Sickness Behavior and Depressive-Like Behavior Induced by Lipopolysaccharide in Rats via Neuroinflammatory Pathway
Q35174754Proposed mechanisms of action for prostate cancer vaccines.
Q42767187Protection from lethal septic peritonitis by neutralizing the biological function of interleukin 27.
Q61812585Protective Effects of Astragaloside IV against LPS-Induced Endometritis in Mice through Inhibiting Activation of the NF-κB, p38 and JNK Signaling Pathways
Q41138304Protective effects of hyperbaric oxygen treatment against spinal cord injury in rats via toll-like receptor 2/nuclear factor-κB signaling
Q79314823Protective effects of nafamostat mesilate on liver injury induced by lipopolysaccharide in rats: possible involvement of CD14 and TLR-4 downregulation on Kupffer cells
Q40706119Protective role of phospholipid oxidation products in endotoxin-induced tissue damage
Q40240877Protein kinase C zeta plays an essential role for Mycobacterium tuberculosis-induced extracellular signal-regulated kinase 1/2 activation in monocytes/macrophages via Toll-like receptor 2.
Q34330109Protein kinase D1 is essential for the proinflammatory response induced by hypersensitivity pneumonitis-causing thermophilic actinomycetes Saccharopolyspora rectivirgula.
Q36984340Protein kinase D1: a new component in TLR9 signaling
Q34978109Protein signaling networks from single cell fluctuations and information theory profiling
Q28079325Proteomic discovery of host kinase signaling in bacterial infections
Q40618435Pseudomonas aeruginosa Flagella Activate Airway Epithelial Cells through asialoGM1 and Toll-Like Receptor 2 as well as Toll-Like Receptor 5
Q41470430Puerarin protects brain tissue against cerebral ischemia/reperfusion injury by inhibiting the inflammatory response
Q36212676Pulmonary DNA vaccination: concepts, possibilities and perspectives
Q33597147Pulmonary infection with an interferon-gamma-producing Cryptococcus neoformans strain results in classical macrophage activation and protection
Q54307096Pulmonary intravascular macrophages as proinflammatory cells in heaves, an asthma-like equine disease.
Q39029483Punicalagin inhibits inflammation in LPS-induced RAW264.7 macrophages via the suppression of TLR4-mediated MAPKs and NF-κB activation
Q28579018Pyrexia, anorexia, adipsia, and depressed motor activity in rats during systemic inflammation induced by the Toll-like receptors-2 and -6 agonists MALP-2 and FSL-1
Q35101552Quantification of poly(I:C)-mediated protection against genital herpes simplex virus type 2 infection.
Q41860012Quiescent hepatic stellate cells functionally contribute to the hepatic innate immune response via TLR3.
Q34311133RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation
Q24303890RNA interference of interferon regulatory factor-1 gene expression in THP-1 cell line leads to Toll-like receptor-4 overexpression/activation as well as up-modulation of annexin-II
Q47592083Radiation-enhanced delivery of systemically administered amphiphilic-CpG oligodeoxynucleotide
Q38352474Ras participates in CpG oligodeoxynucleotide signaling through association with toll-like receptor 9 and promotion of interleukin-1 receptor-associated kinase/tumor necrosis factor receptor-associated factor 6 complex formation in macrophages
Q34441157Recent advances in vaccinology
Q34376294Recent developments in adjuvants for vaccines against infectious diseases
Q79717125Receptor mediated targeting of M-cells
Q64976151Recognition of Lipopolysaccharide and Activation of NF-κB by Cytosolic Sensor NOD1 in Teleost Fish.
Q24530569Recognition of Staphylococcus aureus by the innate immune system
Q35044748Recognition of pathogen-associated molecular patterns by TLR family
Q47547441Recombinant Mtb9.8 of Mycobacterium bovis stimulates TNF-α and IL-1β secretion by RAW264.7 macrophages through activation of NF-κB pathway via TLR2.
Q49885466Recombinant expressed vasoactive intestinal peptide analogue ameliorates TNBS-induced colitis in rats
Q42748123Rectal administration of lipopolysaccharide and ovalbumin ameliorates acute murine colitis
Q98205141Reduced Mrp2 surface availability as PI3Kγ-mediated hepatocytic dysfunction reflecting a hallmark of cholestasis in sepsis
Q47776450Reduced levels of soluble CD14 in atopic children
Q36316635Reducing the immunostimulatory activity of CpG-containing plasmid DNA vectors for non-viral gene therapy
Q41658682Redundant and cooperative interactions between TLR5 and NLRC4 in protective lung mucosal immunity against Pseudomonas aeruginosa.
Q34355187Regulation of Fasting Fuel Metabolism by Toll-Like Receptor 4
Q40788714Regulation of MARCKS and MARCKS-related protein expression in BV-2 microglial cells in response to lipopolysaccharide
Q37363311Regulation of TREM expression in hepatic macrophages and endothelial cells during acute endotoxemia
Q39817421Regulation of Toll-like receptor 4-associated MD-2 in intestinal epithelial cells: a comprehensive analysis.
Q73801052Regulation of macrophage inflammatory protein-2 gene expression in response to oligodeoxynucleotide containing CpG motifs in RAW 264.7 cells
Q35839848Regulation of macrophage procoagulant responses by the tissue factor cytoplasmic domain in endotoxemia.
Q33770420Regulation of the deubiquitinating enzyme CYLD by IkappaB kinase gamma-dependent phosphorylation
Q60045612Regulators of Salmonella-host interaction identified by peripheral blood transcriptome profiling: roles of TGFB1 and TRP53 in intracellular Salmonella replication in pigs
Q28646148Relationship between structures and biological activities of mycoplasmal diacylated lipopeptides and their recognition by toll-like receptors 2 and 6
Q78297202Relationship of changes in interleukin-8 levels and granulocyte elastase activity in gingival crevicular fluid to subgingival periodontopathogens following non-surgical periodontal therapy in subjects with chronic periodontitis
Q33948196Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney
Q35037398Resistance and susceptibility of plants to fungal pathogens.
Q40572941Respiratory epithelial cells regulate lung inflammation in response to inhaled endotoxin
Q34114119Resveratrol differentially modulates inflammatory responses of microglia and astrocytes
Q38865511Review article: novel therapies for hepatitis B virus cure - advances and perspectives.
Q23913728Risk of lung cancer in relation to contiguous windows of endotoxin exposure among female textile workers in Shanghai
Q36237080Robust spinal neuroinflammation mediates mechanical allodynia in Walker 256 induced bone cancer rats
Q33564362Role of CD14 in a mouse model of acute lung inflammation induced by different lipopolysaccharide chemotypes
Q34683318Role of Kupffer cells in alcoholic hepatitis
Q37254135Role of TLR-4 in liver macrophage and endothelial cell responsiveness during acute endotoxemia
Q35585041Role of TLR4/MD-2 and RP105/MD-1 in innate recognition of lipopolysaccharide
Q34715566Role of Toll-like receptor signaling in the apoptotic response of macrophages to Yersinia infection
Q33934368Role of Toll-like receptors 2 and 4 in the induction of cyclooxygenase-2 in vascular smooth muscle
Q33670586Role of direct estrogen receptor signaling in wear particle-induced osteolysis.
Q34143200Role of flagellin and the two-component CheA/CheY system of Listeria monocytogenes in host cell invasion and virulence.
Q37611857Role of gut microbiota in Crohn's disease
Q43753965Role of host response during severe bacterial infection
Q36211187Role of lipid rafts and flagellin in invasion of colonic epithelial cells by Shiga-toxigenic Escherichia coli O113:H21.
Q35949657Role of primary human alveolar epithelial cells in host defense against Francisella tularensis infection
Q39125631Role of the lpxM lipid A biosynthesis pathway gene in pathogenicity of avian pathogenic Escherichia coli strain E058 in a chicken infection model
Q40557136Role of vav1 in the lipopolysaccharide-mediated upregulation of inducible nitric oxide synthase production and nuclear factor for interleukin-6 expression activity in murine macrophages
Q38522801Role of virulence factors on host inflammatory response induced by diarrheagenic Escherichia coli pathotypes
Q38179139Roles for TNF-receptor associated factor 3 (TRAF3) in lymphocyte functions
Q34368121Roles of Toll-like receptors in innate immune responses
Q35024774Roles of toll-like receptors in natural interferon-producing cells as sensors in immune surveillance
Q33916066Ron receptor deficient alveolar myeloid cells exacerbate LPS-induced acute lung injury in the murine lung
Q28571181Rotavirus double-stranded RNA induces apoptosis and diminishes wound repair in rat intestinal epithelial cells
Q37969905S-nitrosylation of surfactant protein D as a modulator of pulmonary inflammation
Q35917608SLAM is a microbial sensor that regulates bacterial phagosome functions in macrophages.
Q78518680SOCS-1 participates in negative regulation of LPS responses
Q42166061Safety and pharmacokinetics of an endotoxin-binding phospholipid emulsion
Q40701269Safflower polysaccharides activate the transcription factor NF-kappa B via Toll-like receptor 4 and induce cytokine production by macrophages
Q37004706Salivary agglutinin/glycoprotein-340/DMBT1: a single molecule with variable composition and with different functions in infection, inflammation and cancer
Q36055459Scavenger receptor A (SR-A) is required for LPS-induced TLR4 mediated NF-κB activation in macrophages
Q36312557Scavenger receptor class a plays a central role in mediating mortality and the development of the pro-inflammatory phenotype in polymicrobial sepsis
Q34959344Schistosome glycoconjugates in host-parasite interplay
Q24555143Secreted MD-2 is a large polymeric protein that efficiently confers lipopolysaccharide sensitivity to Toll-like receptor 4
Q28345219Selective induction of phospholipase D1 in pathogen-activated human monocytes
Q50017340Selenium suppresses inflammation by inducing microRNA-146a in Staphylococcus aureus-infected mouse mastitis model
Q44253547Sensitizing anthrax lethal toxin-resistant macrophages to lethal toxin-induced killing by tumor necrosis factor-alpha
Q28182897Separate Functional Domains of Human MD-2 Mediate Toll-Like Receptor 4-Binding and Lipopolysaccharide Responsiveness
Q37093580Sepsis: from bench to bedside
Q35014302Sequence analysis of multidomain proteins: past perspectives and future directions
Q84066576Sequence variants of Toll-like receptor 4 (TLR4) and the risk of prostate cancer in Korean men
Q40690228Sequential activation of signaling pathways during innate immune responses in Drosophila.
Q57240705Shaping the T cell response to influenza virus
Q33963113Shiga toxin 2 and flagellin from shiga-toxigenic Escherichia coli superinduce interleukin-8 through synergistic effects on host stress-activated protein kinase activation
Q33397541Shiga toxin pathogenesis: kidney complications and renal failure
Q34120536Shigella flexneri Interactions with the Basolateral Membrane Domain of Polarized Model Intestinal Epithelium: Role of Lipopolysaccharide in Cell Invasion and in Activation of the Mitogen-Activated Protein Kinase ERK
Q33695664Short- and long-term changes in gene expression mediated by the activation of TLR9
Q36370978Signal 3 determines tolerance versus full activation of naive CD8 T cells: dissociating proliferation and development of effector function
Q30320937Signal transmission in the plant immune response
Q34974107Signaling networks controlling mucin production in response to Gram-positive and Gram-negative bacteria
Q43913217Signaling pathways involved in the physiological response of mussel hemocytes to bacterial challenge: the role of stress-activated p38 MAP kinases
Q40703200Signalling mechanisms involved in the induction of inducible nitric oxide synthase by Lactobacillus rhamnosus GG, endotoxin, and lipoteichoic acid
Q44147242Significant correlation of TLR4 expression with the clinicopathological features of invasive ductal carcinoma of the breast
Q41957004Similarity of gene expression patterns in human alveolar macrophages in response to Pseudomonas aeruginosa and Burkholderia cepacia
Q77615220Simple genotype analysis of the Asp299Gly polymorphism of the Toll-like receptor-4 gene that is associated with lipopolysaccharide hyporesponsiveness
Q33894934Single nucleotide polymorphisms of Toll-like receptor 4 decrease the risk of development of hepatocellular carcinoma
Q39419036Single-nucleotide polymorphism of Toll-like receptor 4 and interleukin-10 in response to interferon-based therapy in Egyptian chronic hepatitis C patients.
Q28710245Single-nucleotide polymorphisms reveal patterns of allele sharing across the species boundary between rhesus (Macaca mulatta) and cynomolgus (M. fascicularis) macaques
Q28216760Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway
Q41546228Small intestinal bacterial overgrowth and toll-like receptor signaling in patients with non-alcoholic fatty liver disease.
Q41872741Soluble CD14 and CD83 from human neonatal antigen-presenting cells are inducible by commensal bacteria and suppress allergen-induced human neonatal Th2 differentiation
Q34621151Soluble CD14 enriched in colostrum and milk induces B cell growth and differentiation
Q27639729Solution structure and dynamics of the outer membrane enzyme PagP by NMR.
Q48238642Spatio-temporal distribution of inflammatory reaction and expression of TLR2/4 signaling pathway in rat brain following permanent focal cerebral ischemia
Q42439173Species-specific regulation of Toll-like receptor 3 genes in men and mice.
Q28202460Specific missense mutations in NEMO result in hyper-IgM syndrome with hypohydrotic ectodermal dysplasia
Q98465703Specificity of the T Cell Response to Protein Biopharmaceuticals
Q47294548Sperm binding to porcine oviductal cells is mediated by SRCR domains contained in DMBT1.
Q36331056Spermidine Protects against Oxidative Stress in Inflammation Models Using Macrophages and Zebrafish
Q36268287Spleen tyrosine kinase (Syk) as a novel target for allergic asthma and rhinitis
Q44872565Spotted Gar and the Evolution of Innate Immune Receptors.
Q35679540Stachybotrys chartarum-induced hypersensitivity pneumonitis is TLR9 dependent
Q44972574Starch microparticles as an adjuvant in immunisation: effect of route of administration on the immune response in mice
Q37641808Streptococcal co-infection augments Candida pathogenicity by amplifying the mucosal inflammatory response.
Q27702040Structural basis for specific recognition of single-stranded RNA by Toll-like receptor 13
Q45248721Structural origin of endotoxin neutralization and antimicrobial activity of a lactoferrin-based peptide
Q36961012Structural requirements and applications of inhibitory oligodeoxyribonucleotides
Q38671627Structure of the mouse Toll-like receptor 13 ectodomain in complex with a conserved sequence from bacterial 23S ribosomal RNA.
Q55069592Studies on mitogen-activated protein kinase signaling pathway in the alveolar macrophages of chronic bronchitis rats.
Q28397617Subcellular organelle lipidomics in TLR-4-activated macrophages
Q42261747Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens
Q34158166Summary and comparison of the signaling mechanisms of the Toll/interleukin-1 receptor family
Q34402156Sunlight and Vitamin D: A global perspective for health
Q36781277Suppression of inflammation and acute lung injury by Miz1 via repression of C/EBP-δ.
Q59798948Surface engineered polyanhydride-based oral Salmonella subunit nanovaccine for poultry
Q39404432Surfactant protein D inhibits lipopolysaccharide-induced monocyte chemoattractant protein-1 expression in human renal tubular epithelial cells: implication for tubulointerstitial fibrosis
Q40125359Susceptibility to HIV-1 infection is influenced by toll like receptor-2 (-196 to -174) polymorphism in a north Indian population
Q39370971Synergism between interleukin (IL)-17 and Toll-like receptor 2 and 4 signals to induce IL-8 expression in cystic fibrosis airway epithelial cells.
Q39519164Synergistic effect of muramyldipeptide with lipopolysaccharide or lipoteichoic acid to induce inflammatory cytokines in human monocytic cells in culture
Q44885438Synergistic effects of lipopolysaccharide and interferon-gamma in inducing interleukin-8 production in human monocytic THP-1 cells is accompanied by up-regulation of CD14, Toll-like receptor 4, MD-2 and MyD88 expression
Q35545269Synergistic up-regulation of vascular endothelial growth factor (VEGF) expression in macrophages by adenosine A2A receptor agonists and endotoxin involves transcriptional regulation via the hypoxia response element in the VEGF promoter
Q37352457Synthetic resveratrol aliphatic acid inhibits TLR2-mediated apoptosis and an involvement of Akt/GSK3beta pathway
Q47878215Systemic TLR2 Antibody Application in Renal Ischaemia and Reperfusion Injury Decreases AKT Phosphorylation and Increases Apoptosis in the Mouse Kidney
Q35105277Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses
Q35608835T lymphocyte dependence of the antibody response to 'T lymphocyte independent type 2' antigens.
Q37298275TAT-Hsp70 induces neuroprotection against stroke via anti-inflammatory actions providing appropriate cellular microenvironment for transplantation of neural precursor cells
Q53089569TGF-β1 re-programs TLR4 signaling in L. donovani infection: enhancement of SHP-1 and ubiquitin-editing enzyme A20.
Q40675827TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction
Q28214613TIRAP: an adapter molecule in the Toll signaling pathway
Q28201815TIRP, a novel Toll/interleukin-1 receptor (TIR) domain-containing adapter protein involved in TIR signaling
Q39333116TLR-2 and TLR-4 transcriptions in unstimulated blood from dogs with leishmaniosis due to Leishmania infantum at the time of diagnosis and during follow-up treatment
Q35389014TLR-3 is present in human adipocytes, but its signalling is not required for obesity-induced inflammation in adipose tissue in vivo
Q50711764TLR-7 and -9 Stimulation of Peripheral Blood B Cells Indicate Altered TLR Signalling in Primary Sjögren's Syndrome Patients by Increased Secretion of Cytokines.
Q30841825TLR-exosomes exhibit distinct kinetics and effector function.
Q54350178TLR2 and TLR4 gene promoter methylation status during chronic periodontitis.
Q41810950TLR2 and TLR4 signaling pathways are required for recombinant Brucella abortus BCSP31-induced cytokine production, functional upregulation of mouse macrophages, and the Th1 immune response in vivo and in vitro
Q36853515TLR2 is expressed on activated T cells as a costimulatory receptor
Q40555493TLR2 is mobilized into an apical lipid raft receptor complex to signal infection in airway epithelial cells
Q35118932TLR2 ligand induces protection against cerebral ischemia/reperfusion injury via activation of phosphoinositide 3-kinase/Akt signaling
Q34062721TLR2 ligands induce cardioprotection against ischaemia/reperfusion injury through a PI3K/Akt-dependent mechanism
Q39331395TLR2 signaling subpathways regulate TLR9 signaling for the effective induction of IL-12 upon stimulation by heat-killed Brucella abortus
Q33486526TLR2-dependent inhibition of macrophage responses to IFN-gamma is mediated by distinct, gene-specific mechanisms
Q49865104TLR3 Mediates Repair and Regeneration of Damaged Neonatal Heart through Glycolysis Dependent YAP1 Regulated miR-152 Expression
Q35017176TLR4 +896A>G (Asp299Gly) polymorphism is not associated with asthma: a update meta-analysis
Q36985378TLR4 Deficiency Impairs Oligodendrocyte Formation in the Injured Spinal Cord
Q36666867TLR4 links podocytes with the innate immune system to mediate glomerular injury
Q44004513TLR4-dependent lipopolysaccharide signalling in epithelial cells is independent of extracellular protease activity
Q54540160TLR4-dependent recognition of lipopolysaccharide by epithelial cells requires sCD14.
Q39745001TLR4: the receptor bridging Acanthamoeba challenge and intracellular inflammatory responses in human corneal cell lines
Q90430895TLR5 is a new reporter for triple-negative breast cancer indicated by radioimmunoimaging and fluorescent staining
Q59804792TLR9 Signaling Suppresses the Canonical Plasma Cell Differentiation Program in Follicular B Cells
Q34775922TLR9 promoter polymorphism is associated with both an increased susceptibility to gastric carcinoma and poor prognosis
Q42427813TLR9-dependent IL-23/IL-17 is required for the generation of Stachybotrys chartarum-induced hypersensitivity pneumonitis
Q37004059TNF-alpha-mediated inflammation in cerebral aneurysms: a potential link to growth and rupture
Q37678189TNF-alpha/NF-kappaB/Snail pathway in cancer cell migration and invasion
Q39060065TRAF5 negatively regulates TLR signaling in B lymphocytes
Q28177538TREM-1 (triggering receptor expressed on myeloid cells): a new player in acute inflammatory responses
Q28185818TREM-1 amplifies inflammation and is a crucial mediator of septic shock
Q74531846TREM-1 in sepsis
Q36387097TRPV4 Mechanosensitive Ion Channel Regulates Lipopolysaccharide-Stimulated Macrophage Phagocytosis
Q90862887Targeting cell signaling in allergic asthma
Q35549421Targeting dendritic cells for priming cellular immune responses
Q102210856Targeting nuclear acid-mediated immunity in cancer immune checkpoint inhibitor therapies
Q40544969Targeting of scavenger receptor class B type I by synthetic amphipathic alpha-helical-containing peptides blocks lipopolysaccharide (LPS) uptake and LPS-induced pro-inflammatory cytokine responses in THP-1 monocyte cells
Q89060807Targeting toll-like receptor-4 (TLR4)-an emerging therapeutic target for persistent pain states
Q78045545Tetanus antigen modulates the gene expression profile of aluminum phosphate adjuvant in spleen lymphocytes in vivo
Q35215350Th1 cytokine-secreting recombinant Mycobacterium bovis bacillus Calmette-Guérin and prospective use in immunotherapy of bladder cancer.
Q54708356The 3020insC mutation of the NOD2/CARD15 gene in patients with periodontal disease.
Q99591180The Anti-Inflammatory Effect of Taurine on Cardiovascular Disease
Q39134389The Anti-inflammatory Activities of Two Major Withanolides from Physalis minima Via Acting on NF-κB, STAT3, and HO-1 in LPS-Stimulated RAW264.7 Cells.
Q54696973The CD14 -159C-to-T promoter polymorphism in periodontal disease.
Q31051692The Escherichia coli gene encoding the UDP-2,3-diacylglucosamine pyrophosphatase of lipid A biosynthesis
Q89658487The Impact of IL-6 and IL-10 Gene Polymorphisms in Diffuse Large B-Cell Lymphoma Risk and Overall Survival in an Arab Population: A Case-Control Study
Q33322613The Innate Immune Database (IIDB)
Q38913922The N terminus of type III secretion needle protein YscF from Yersinia pestis functions to modulate innate immune responses
Q48625224The PI3K/Akt pathway is required for LPS activation of microglial cells
Q36053487The Poly-γ-d-Glutamic Acid Capsule Surrogate of the Bacillus anthracis Capsule Is a Novel Toll-Like Receptor 2 Agonist
Q92704712The Postembryonic Development of the Immunological Barrier in the Chicken Spleens
Q90019825The Protective Effects of Terpinen-4-ol on LPS-Induced Acute Lung Injury via Activating PPAR-γ
Q41832550The Rhizome Mixture of Anemarrhena asphodeloides and Coptidis chinensis Ameliorates Acute and Chronic Colitis in Mice by Inhibiting the Binding of Lipopolysaccharide to TLR4 and IRAK1 Phosphorylation
Q28203717The TNF and TNF receptor superfamilies: integrating mammalian biology
Q37456375The TRIF-dependent signaling pathway is not required for acute cerebral ischemia/reperfusion injury in mice
Q28249049The Toll pathway is important for an antiviral response in Drosophila
Q34135174The Toll receptor family.
Q73361348The Toll-Like Receptor 5 Stimulus Bacterial Flagellin Induces Maturation and Chemokine Production in Human Dendritic Cells
Q42235635The activation of macrophage and upregulation of CD40 costimulatory molecule in lipopolysaccharide-induced acute lung injury.
Q28511605The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors
Q34770567The aetiology of bacterial vaginosis.
Q35190410The airway microbiome of intubated premature infants: characteristics and changes that predict the development of bronchopulmonary dysplasia
Q40520876The amino-terminal region of toll-like receptor 4 is essential for binding to MD-2 and receptor translocation to the cell surface
Q46575214The anti-endotoxic effects of the KSL-W decapeptide on Escherichia coli O55:B5 and various oral lipopolysaccharides
Q36122823The anti-inflammatory effect and potential mechanism of cardamonin in DSS-induced colitis
Q34297072The arms race is ancient history in Arabidopsis, the wildflower
Q35166994The association between inflammation-related genes and serum androgen levels in men: the prostate, lung, colorectal, and ovarian study
Q35419069The association of polymorphisms of TLR4 and CD14 genes with susceptibility to sepsis in a Chinese population
Q40112182The bacterium, nontypeable Haemophilus influenzae, enhances host antiviral response by inducing Toll-like receptor 7 expression: evidence for negative regulation of host anti-viral response by CYLD.
Q77228404The biology of endotoxin
Q53914180The calcineurin inhibitor RCAN1 is involved in cultured macrophage and in vivo immune response
Q35169987The chaperone balance hypothesis: the importance of the extracellular to intracellular HSP70 ratio to inflammation-driven type 2 diabetes, the effect of exercise, and the implications for clinical management
Q34129320The control and facilitation of MHC class II antigen processing by the BCR.
Q34595364The critical role of mast cells in allergy and inflammation
Q82252842The delayed response of Toll-like receptors may relate to Pseudomonas aeruginosa keratitis exacerbating rapidly at the early stages of infection
Q34330221The domains of apoptosis: a genomics perspective
Q42957702The effect of CpG-ODN on antigen presenting cells of the foal
Q35619585The effect of dexmedetomidine on inflammatory response of septic rats
Q54329253The effect of microbial-nutrient interaction on the immune system of young chicks after early probiotic and organic acid administration.
Q43770319The effects of IL-6 and TNF-alpha as molecular adjuvants on immune responses to FMDV and maturation of dendritic cells by DNA vaccination
Q90651199The emerging chemical patterns applied in predicting human toll-like receptor 8 agonists
Q34120383The endoplasmic reticulum-resident heat shock protein Gp96 activates dendritic cells via the Toll-like receptor 2/4 pathway
Q34573771The enemy within: keeping self-reactive T cells at bay in the periphery
Q24530086The evolution of vertebrate Toll-like receptors
Q81077941The expression of E-selectin and chemokines in the cultured human lymphatic endothelium with lipopolysaccharides
Q28504661The extracellular matrix protein mindin is a pattern-recognition molecule for microbial pathogens
Q24296402The extracellular toll-like receptor 2 domain directly binds peptidoglycan derived from Staphylococcus aureus
Q34647328The front line of enteric host defense against unwelcome intrusion of harmful microorganisms: mucins, antimicrobial peptides, and microbiota
Q28592020The function of heme-regulated eIF2alpha kinase in murine iron homeostasis and macrophage maturation
Q39364591The homeobox transcription factor VentX controls human macrophage terminal differentiation and proinflammatory activation
Q97530291The immune response to infection in the bladder
Q35144175The immunopathogenesis of meningococcal disease
Q29622909The immunopathogenesis of sepsis
Q44929546The impact of hyperoxia on the neonatal and adult developing dendritic cell
Q33531757The induction of colitis and ileitis in mice is associated with marked increases in intestinal concentrations of stimulants of TLRs 2, 4, and 5
Q28185796The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
Q38162221The innate immune system in Alzheimer's disease.
Q35548901The intestine and its microflora are partners for the protection of the host: report on the Danone Symposium “The Intelligent Intestine,” held in Paris, June 14, 2002
Q54430820The investigation of toll-like receptor 3, 9 and 10 gene polymorphisms in Turkish rheumatoid arthritis patients.
Q84289753The involvement of TLR2 in cytokine and reactive oxygen species (ROS) production by PBMCs in response to Leishmania major phosphoglycans (PGs)
Q77291248The lipopolysaccharide co-receptor CD14 is present and functional in seminal plasma and expressed on spermatozoa
Q34502370The many roles of the class A macrophage scavenger receptor
Q34493037The molecular basis of innate immunity in the horseshoe crab
Q40816643The p38 mitogen-activated kinase pathway regulates the human interleukin-10 promoter via the activation of Sp1 transcription factor in lipopolysaccharide-stimulated human macrophages
Q33813977The personal touch: strategies toward personalized vaccines and predicting immune responses to them
Q35571920The plasmacytoid monocyte/interferon producing cells
Q35843784The potential for Toll-like receptors to collaborate with other innate immune receptors
Q41463392The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4.
Q80052002The quest for new therapies in patients with cirrhosis and sepsis. Time to move from the lab to the bedside
Q38424338The regulatory roles of NADPH oxidase, intra- and extra-cellular HSP70 in pancreatic islet function, dysfunction and diabetes.
Q44437737The role of Toll-like receptor (TLR) 2 and 9 in renal ischemia and reperfusion injury
Q36559267The role of Toll-like receptors in non-infectious lung injury
Q40711946The role of adsorbed endotoxin in particle-induced stimulation of cytokine release
Q34313156The role of endotoxin and its receptors in allergic disease
Q36994006The role of gut microbiota on insulin resistance
Q34731185The role of human T-lymphocyte-monocyte contact in inflammation and tissue destruction
Q35940078The role of immune tolerance in preventing and treating arthritis
Q37478120The role of inflammatory mediators in the pathogenesis of otitis media and sequelae
Q37834316The role of lipopolysaccharide/toll-like receptor 4 signaling in chronic liver diseases.
Q40359173The role of toll-like and protease-activated receptors and associated intracellular signaling in Porphyromonas gingivalis-infected gingival fibroblasts
Q44014087The role of toll-like receptor 2 in the recognition of Aggregatibacter actinomycetemcomitans
Q35575072The role of toll-like receptor variants in acute anterior uveitis
Q52964856The role of toll-like receptors (TLRs) in bacteria-induced maturation of murine dendritic cells (DCS). Peptidoglycan and lipoteichoic acid are inducers of DC maturation and require TLR2.
Q34546023The signaling adaptor TRAF1 negatively regulates Toll-like receptor signaling and this underlies its role in rheumatic disease.
Q40675160The t-SNARE syntaxin 4 is regulated during macrophage activation to function in membrane traffic and cytokine secretion.
Q34380094The tumor microenvironment of colorectal cancer: stromal TLR-4 expression as a potential prognostic marker
Q37942501The type I interferon response during viral infections: a "SWOT" analysis
Q84504653Therapeutic HPV DNA vaccines
Q35194755Therapeutic approaches to innate immunity: severe sepsis and septic shock
Q34441123Therapeutic aspects of tolerance.
Q56082684Thermal biology in insect-parasite interactions
Q33556819Thioredoxin peroxidase secreted by Fasciola hepatica induces the alternative activation of macrophages
Q33690260Tickling the TLR7 to cure viral hepatitis
Q46460985Time-course expression of Toll-like receptors 2 and 4 in inflammatory bowel disease and homeostatic effect of VIP.
Q34260232Toll meets bacterial CpG-DNA.
Q73739736Toll of allergy reduced by probiotics
Q27313529Toll-Like Receptor 4 Deficiency Impairs Motor Coordination
Q35585033Toll-like Receptors and Their Signaling Mechanisms
Q54732972Toll-like receptor (TLR) 2 and 4 mutations in periodontal disease.
Q40080719Toll-like receptor (TLR) 2 induced through TLR4 signaling initiated by Helicobacter pylori cooperatively amplifies iNOS induction in gastric epithelial cells
Q35008279Toll-like receptor (TLR)-mediated innate immune responses in the control of hepatitis B virus (HBV) infection
Q53449726Toll-like receptor 1 gene polymorphisms in childhood IgA nephropathy: a case-control study in the Korean population
Q34194793Toll-like receptor 2 deficiency delays pneumococcal phagocytosis and impairs oxidative killing by granulocytes
Q37144975Toll-like receptor 2 deficiency is associated with enhanced severity of group B streptococcal disease
Q54476642Toll-like receptor 2 gene polymorphism and its relationship with SCS in dairy cattle.
Q33527571Toll-like receptor 2 gene polymorphisms, pulmonary tuberculosis, and natural killer cell counts
Q40705550Toll-like receptor 2 is required for optimal control of Listeria monocytogenes infection
Q35870750Toll-like receptor 2 promotes T helper 17 cells response in hepatitis B virus infection
Q43807744Toll-like receptor 2 siRNA suppresses corneal inflammation and attenuates Aspergillus fumigatus keratitis in rats
Q30500126Toll-like receptor 2-dependent NF-kappaB activation is involved in nontypeable Haemophilus influenzae-induced monocyte chemotactic protein 1 up-regulation in the spiral ligament fibrocytes of the inner ear.
Q40819427Toll-like receptor 2-mediated NF-kappa B activation requires a Rac1-dependent pathway
Q36825545Toll-like receptor 3 plays a central role in cardiac dysfunction during polymicrobial sepsis
Q80965217Toll-like receptor 3 regulates Mx expression in rare minnow Gobiocypris rarus after viral infection
Q35697425Toll-like receptor 3: a link between toll-like receptor, interferon and viruses
Q36423082Toll-like receptor 4 expression in the epithelium of inflammatory periapical lesions. An immunohistochemical study
Q53674487Toll-like receptor 4 is involved in bacterial endotoxin-induced endothelial cell injury and SOC-mediated calcium regulation.
Q45710826Toll-like receptor 4 is not involved in host defense against respiratory tract infection with Sendai virus
Q24294920Toll-like receptor 4 is required for optimal development of Th2 immune responses: role of dendritic cells
Q37188449Toll-like receptor 4 mediates chronic restraint stress-induced immune suppression
Q33711540Toll-like receptor 4 mediates the antitumor host response induced by a 55-kilodalton protein isolated from Aeginetia indica L., a parasitic plant
Q35165860Toll-like receptor 4 plays an anti-HBV role in a murine model of acute hepatitis B virus expression
Q44457578Toll-like receptor 4 plays no role in susceptibility of mice to Mycobacterium tuberculosis infection
Q33851201Toll-like receptor 4 polymorphisms are associated with resistance to Legionnaires' disease
Q40216944Toll-like receptor 4 region Glu24-Lys47 is a site for MD-2 binding: importance of CYS29 and CYS40.
Q91689817Toll-like receptor 6 expression, sequence variants, and their association with colorectal cancer risk
Q34406452Toll-like receptor 9 gene mutations and polymorphisms in Japanese ulcerative colitis patients
Q37498029Toll-like receptor 9 is required for chronic stress-induced immune suppression
Q36747187Toll-like receptor 9 regulates the lung macrophage phenotype and host immunity in murine pneumonia caused by Legionella pneumophila
Q44592739Toll-like receptor 9 triggers an innate immune response to helper-dependent adenoviral vectors.
Q40055987Toll-like receptor 9-dependent macrophage activation by Entamoeba histolytica DNA.
Q42007907Toll-like receptor polymorphisms compromise the inflammatory response against bacterial antigen translocation in cirrhosis.
Q35189960Toll-like receptor signaling
Q35111610Toll-like receptor-1 and receptor-2 and Beta-defensin in postcholecystectomy bile duct injury
Q40815279Toll-like receptor-2 mediates Treponema glycolipid and lipoteichoic acid-induced NF-kappaB translocation
Q34443986Toll-like receptor-4 pathway is required for the pathogenesis of human chronic endometritis
Q51158850Toll-like receptor-associated keratitis and strategies for its management.
Q52858571Toll-like receptor-mediated responses of primary intestinal epithelial cells during the development of colitis.
Q40056654Toll-like receptors (TLRs) expression and function in response to inactivate hyphae of Fusarium solani in immortalized human corneal epithelial cells.
Q82776333Toll-like receptors 2 and 4 in renal ischemia/reperfusion injury
Q40055691Toll-like receptors 2 and 4 mediate Abeta(1-42) activation of the innate immune response in a human monocytic cell line
Q24624348Toll-like receptors and B-cell receptors synergize to induce immunoglobulin class-switch DNA recombination: relevance to microbial antibody responses
Q47820000Toll-like receptors and TLR-mediated signaling: more questions than answers
Q38151944Toll-like receptors and liver disease
Q82973353Toll-like receptors and the eye
Q37469924Toll-like receptors as targets in chronic liver diseases
Q28070077Toll-like receptors in pathophysiology of liver diseases
Q35495496Toll-like receptors in secondary obstructive cholangiopathy
Q29615190Toll-like receptors: critical proteins linking innate and acquired immunity
Q34493051Toll-like receptors: key mediators of microbe detection.
Q37810952Toll-like receptors: new players in myocardial ischemia/reperfusion injury
Q24297037Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3...
Q80620358Tomato transcriptional changes in response to Clavibacter michiganensis subsp. michiganensis reveal a role for ethylene in disease development
Q35059633Topical ALA-Photodynamic Therapy for Acne Can Induce Apoptosis of Sebocytes and Down-regulate Their TLR-2 and TLR-4 Expression
Q54120276Topical Dexamethasone Administration Impairs Protein Synthesis and Neuronal Regeneration in the Olfactory Epithelium.
Q33267137Topomimetics of amphipathic beta-sheet and helix-forming bactericidal peptides neutralize lipopolysaccharide endotoxins
Q43018197Total synthesis of an immunomodulatory phosphoglycolipid from thermophilic bacteria
Q39627759Towards Alzheimer's root cause: ECSIT as an integrating hub between oxidative stress, inflammation and mitochondrial dysfunction. Hypothetical role of the adapter protein ECSIT in familial and sporadic Alzheimer's disease pathogenesis
Q52139531Trans-Cinnamaldehyde, An Essential Oil in Cinnamon Powder, Ameliorates Cerebral Ischemia-Induced Brain Injury via Inhibition of Neuroinflammation Through Attenuation of iNOS, COX-2 Expression and NFκ-B Signaling Pathway.
Q34157917Transcription analysis on response of porcine alveolar macrophages to Haemophilus parasuis.
Q46538908Transcriptional Profiling of Banana Shrimp Fenneropenaeus merguiensis with Differing Levels of Viral Load
Q37343959Transcriptional regulation of the novel Toll-like receptor Tlr13.
Q38651876Transcriptomes and expression profiling of deep-sea corals from the Red Sea provide insight into the biology of azooxanthellate corals
Q33792003Treatment with LL-37 peptide enhances antitumor effects induced by CpG oligodeoxynucleotides against ovarian cancer
Q33931633Trehalose 6,6'-dimycolate (cord factor) of Mycobacterium tuberculosis induces foreign-body- and hypersensitivity-type granulomas in mice
Q44567851Treponemal phospholipids inhibit innate immune responses induced by pathogen-associated molecular patterns
Q28258400Triad3A, an E3 ubiquitin-protein ligase regulating Toll-like receptors
Q55363854Trichomonas vaginalis Induces Production of Proinflammatory Cytokines in Mouse Macrophages Through Activation of MAPK and NF-κB Pathways Partially Mediated by TLR2.
Q36041852Triggering receptor expressed on myeloid cells and 5'adenosine monophosphate-activated protein kinase in the inflammatory response: a potential therapeutic target
Q34744159Tumour growth inhibition by an imidazoquinoline is associated with c-Myc down-regulation in urothelial cell carcinoma
Q36406626Tumour necrosis factor alpha downregulates human hemojuvelin expression via a novel response element within its promoter.
Q90726349Unmethylated CpG motif-containing genomic DNA fragment of Bacillus calmette-guerin promotes macrophage functions through TLR9-mediated activation of NF-κB and MAPKs signaling pathways
Q35692150Up in Arms: Immune and Nervous System Response to Sea Star Wasting Disease
Q34032259Upregulated expression of S100A8 in mice brain after focal cerebral ischemia reperfusion
Q35826404Use of CpG oligodeoxynucleotides as immune adjuvants
Q42733178Use of lipolanthionine peptide, a toll-like receptor 2 inhibitor, enhances transdermal delivery efficiency
Q53949766Vaccination of mice against invasive aspergillosis with recombinant Aspergillus proteins and CpG oligodeoxynucleotides as adjuvants.
Q35557428Vaccine adjuvants: role and mechanisms of action in vaccine immunogenicity
Q37179294Vasoactive intestinal peptide attenuates liver ischemia/reperfusion injury in mice via the cyclic adenosine monophosphate-protein kinase a pathway
Q37043527VdNEP, an elicitor from Verticillium dahliae, induces cotton plant wilting.
Q36978505Ventilator-induced lung injury. Similarity and differences between children and adults
Q43593256Vinpocetine alleviate cerebral ischemia/reperfusion injury by down-regulating TLR4/MyD88/NF-κB signaling
Q35206853Viruses and Toll-like receptors.
Q28220397Viruses and interferon: a fight for supremacy
Q90042760WISP1 and TLR4 on Macrophages Contribute to Ventilator-Induced Lung Injury
Q33983437War and peace at mucosal surfaces
Q39068343Wedelolactone inhibits LPS-induced pro-inflammation via NF-kappaB pathway in RAW 264.7 cells
Q46240258Why does Crohn's disease usually occur in terminal ileum?
Q28205553With a mere nod, uveitis enters a new era
Q40446467Withanolides against TLR4-Activated Innate Inflammatory Signalling Pathways: A Comparative Computational and Experimental Study.
Q34369064Women and autoimmune diseases
Q42732189Wound healing of intestinal epithelial cells
Q34145003Xanthomonas oryzae pv oryzae triggers immediate transcriptomic modulations in rice
Q36371199Yersinia V-antigen exploits toll-like receptor 2 and CD14 for interleukin 10-mediated immunosuppression
Q34261331Zebrafish--an emerging genetic model for the study of cytokines and hematopoiesis in the era of functional genomics
Q35182043Zinc prevents sickness behavior induced by lipopolysaccharides after a stress challenge in rats.
Q81761827[Pathophysiology of acne]
Q75356546[Role of the innate immune response in sepsis]
Q31159559allograft inflammatory factor 1 functions as a pro-inflammatory cytokine in the oyster, Crassostrea ariakensis
Q45085694beta2-adrenergic receptor stimulation-induced immunosuppressive effects possibly through down-regulation of co-stimulatory molecules, ICAM-1, CD40 and CD14 on monocytes
Q57675135c-Fos suppresses systemic inflammatory response to endotoxin
Q42913373c-Fos-deficient mice are susceptible to Salmonella enterica serovar Typhimurium infection
Q38735267c-Jun Is Required for Nuclear Factor-κB-Dependent, LPS-Stimulated Fos-Related Antigen-1 Transcription in Alveolar Macrophages
Q90724296β-1,3/1,6-glucans and Immunity: State of the Art and Future Directions
Q41928484β-2 microglobulin is unsuitable as an internal reference gene for the analysis of gene expression in human colorectal cancer