High-resolution NMR analysis of the conformations of native and base analog substituted retroviral and LTR-retrotransposon PPT primers

scientific article published on March 2008

High-resolution NMR analysis of the conformations of native and base analog substituted retroviral and LTR-retrotransposon PPT primers is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.CHEMBIOL.2008.01.012
P932PMC publication ID2729084
P698PubMed publication ID18355725
P5875ResearchGate publication ID5496212

P2093author name stringStuart F J Le Grice
John P Marino
Robert G Brinson
Daniela Lener
Danielle M Brabazon
Hye Young Yi-Brunozzi
P2860cites workThe difluorotoluene debate--a decade laterQ36626648
Structural probing of the HIV-1 polypurine tract RNA:DNA hybrid using classic nucleic acid ligandsQ36649670
Using pyrrolo-deoxycytosine to probe RNA/DNA hybrids containing the human immunodeficiency virus type-1 3' polypurine tract.Q37518702
Comparison of the conformation of an oligonucleotide containing a central G-T base pair with the non-mismatch sequence by proton NMR.Q40566245
Interaction of p55 reverse transcriptase from the Saccharomyces cerevisiae retrotransposon Ty3 with conformationally distinct nucleic acid duplexesQ42625261
Identification of a sequence element immediately upstream of the polypurine tract that is essential for replication of simian immunodeficiency virusQ42648096
Pre-existing distortions in nucleic acid structure aid polypurine tract selection by HIV-1 reverse transcriptaseQ43903247
Mutating conserved residues in the ribonuclease H domain of Ty3 reverse transcriptase affects specialized cleavage eventsQ43982347
Nonpolar thymine isosteres in the Ty3 polypurine tract DNA template modulate processing and provide a model for its recognition by Ty3 reverse transcriptaseQ44429273
RNA probes of steric effects in active sites: high flexibility of HIV-1 reverse transcriptaseQ46241090
Comparison of the thermodynamic stabilities and solution conformations of DNA.RNA hybrids containing purine-rich and pyrimidine-rich strands with DNA and RNA duplexesQ71571731
Thermodynamic parameters to predict stability of RNA/DNA hybrid duplexesQ71709608
Mimicking the Structure and Function of DNA: Insights into DNA Stability and ReplicationQ73666805
Thermodynamics-structure relationship of single mismatches in RNA/DNA duplexesQ74311706
Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA:DNAQ24545723
An unusual sugar conformation in the structure of an RNA/DNA decamer of the polypurine tract may affect recognition by RNase HQ27642626
Gene silencing activity of siRNAs with a ribo-difluorotoluyl nucleotideQ27643284
Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate requirements by the human RISC Ago2 enzymeQ27648323
Solution structure of r(gaggacug):d(CAGTCCTC) hybrid: implications for the initiation of HIV-1 (+)-strand synthesisQ27739404
NMR solution structure of a DNA dodecamer containing single G.T mismatchesQ27765702
Solution structure of a DNA duplex containing a replicable difluorotoluene-adenine pairQ27765958
Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistanceQ27766086
The crystal structure of the RNA/DNA hybrid r(GAAGAGAAGC). d(GCTTCTCTTC) shows significant differences to that found in solutionQ27766391
NMRPipe: a multidimensional spectral processing system based on UNIX pipesQ27860859
Improved spectral resolution in cosy 1H NMR spectra of proteins via double quantum filteringQ29618846
Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNAQ29620616
Imino proton exchange and base-pair kinetics in RNA duplexesQ30657018
Hydrophobic, Non-Hydrogen-Bonding Bases and Base Pairs in DNAQ34157403
Experimental Measurement of Aromatic Stacking Affinities in the Context of Duplex DNAQ34157577
A ribose sugar conformational switch in the LTR-retrotransposon Ty3 polypurine tract-containing RNA/DNA hybridQ34312399
Reverse transcription of retroviruses and LTR retrotransposonsQ34385549
Purine analog substitution of the HIV-1 polypurine tract primer defines regions controlling initiation of plus-strand DNA synthesisQ35646719
'Binding, bending and bonding': polypurine tract-primed initiation of plus-strand DNA synthesis in human immunodeficiency virusQ35796073
Hydrolysis of RNA/DNA hybrids containing nonpolar pyrimidine isosteres defines regions essential for HIV type 1 polypurine tract selectionQ36160662
P433issue3
P921main subjectretrotransposonQ413988
P304page(s)254-262
P577publication date2008-03-01
P1433published inChemistry and BiologyQ15758410
P1476titleHigh-resolution NMR analysis of the conformations of native and base analog substituted retroviral and LTR-retrotransposon PPT primers
P478volume15

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cites work (P2860)
Q38294228Applying Thymine Isostere 2,4-Difluoro-5-Methylbenzene as a NMR Assignment Tool and Probe of Homopyrimidine/Homopurine Tract Structural Dynamics.
Q36972129Examining the ribonuclease H primer grip of HIV-1 reverse transcriptase by charge neutralization of RNA/DNA hybrids
Q37149739Fidelity of plus-strand priming requires the nucleic acid chaperone activity of HIV-1 nucleocapsid protein
Q47364014Mechanism of polypurine tract primer generation by HIV-1 reverse transcriptase
Q33574015Probing anomalous structural features in polypurine tract-containing RNA-DNA hybrids with neomycin B
Q34092798Reverse transcriptase in motion: conformational dynamics of enzyme-substrate interactions
Q35259898Revisiting plus-strand DNA synthesis in retroviruses and long terminal repeat retrotransposons: dynamics of enzyme: substrate interactions
Q34775658Role of HIV-1 nucleocapsid protein in HIV-1 reverse transcription
Q37272440SHAMS: combining chemical modification of RNA with mass spectrometry to examine polypurine tract-containing RNA/DNA hybrids
Q36649670Structural probing of the HIV-1 polypurine tract RNA:DNA hybrid using classic nucleic acid ligands
Q39287405Structural studies of RNA/DNA polypurine tracts.
Q27676917Structure of an RNA/DNA dodecamer corresponding to the HIV-1 polypurine tract at 1.6 Å resolution
Q41626539Synthesis and incorporation of 13C-labeled DNA building blocks to probe structural dynamics of DNA by NMR.
Q27689454Ty3 reverse transcriptase complexed with an RNA-DNA hybrid shows structural and functional asymmetry

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