| scholarly article | Q13442814 |
| retracted paper | Q45182324 |
| P50 | author | Sivareddy Kotla | Q58836521 |
| P2093 | author name string | Gadiparthi N Rao | |
| Nikhlesh K Singh | |||
| Mark R Heckle | |||
| Ravisekhar Gadepalli | |||
| Shailendra K Verma | |||
| P2860 | cites work | Thrombin-activated human endothelial cells support monocyte adhesion in vitro following expression of intercellular adhesion molecule-1 (ICAM-1; CD54) and vascular cell adhesion molecule-1 (VCAM-1; CD106). | Q47725276 |
| TRAIL/Apo2L mediates the release of procoagulant endothelial microparticles induced by thrombin in vitro: a potential mechanism linking inflammation and coagulation. | Q51782206 | ||
| Thrombin and protease-activated receptors (PARs) in atherothrombosis. | Q53497901 | ||
| Early inflammatory reactions in atherosclerosis are induced by proline-rich tyrosine kinase/reactive oxygen species-mediated release of tumor necrosis factor-alpha and subsequent activation of the p21Cip1/Ets-1/p300 system | Q56557773 | ||
| Macrophages and Platelets Are the Major Source of Protease Nexin-1 in Human Atherosclerotic Plaque | Q58425841 | ||
| Thrombin regulation of platelet interaction with damaged vessel wall and isolated collagen type I at arterial flow conditions in a porcine model: effects of hirudins, heparin, and calcium chelation | Q60924678 | ||
| The Adaptor Protein Gab1 Couples the Stimulation of Vascular Endothelial Growth Factor Receptor-2 to the Activation of Phosphoinositide 3-Kinase | Q64355677 | ||
| The adaptor protein Gab1 couples the stimulation of vascular endothelial growth factor receptor-2 to the activation of phosphoinositide 3-kinase | Q64377712 | ||
| Monocytes in atherosclerosis: subsets and functions | Q22251045 | ||
| Activation of gp130 transduces hypertrophic signal through interaction of scaffolding/docking protein Gab1 with tyrosine phosphatase SHP2 in cardiomyocytes | Q24307683 | ||
| Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency | Q24313425 | ||
| Identification of a novel guanine nucleotide exchange factor for the Rho GTPase | Q24324614 | ||
| Galpha 12 activates Rho GTPase through tyrosine-phosphorylated leukemia-associated RhoGEF. | Q24541352 | ||
| The Gab1 PH domain is required for localization of Gab1 at sites of cell-cell contact and epithelial morphogenesis downstream from the met receptor tyrosine kinase | Q24554529 | ||
| Essential role of Gab1 for signaling by the c-Met receptor in vivo | Q24685688 | ||
| PAR-1 and thrombin: the ties that bind the microenvironment to melanoma metastasis | Q27001552 | ||
| Rho GTPases in cell biology | Q27860969 | ||
| Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor | Q28238303 | ||
| Protease-activated receptors (PAR1 and PAR2) contribute to tumor cell motility and metastasis | Q28274536 | ||
| Grb2 forms an inducible protein complex with CD28 through a Src homology 3 domain-proline interaction | Q28278858 | ||
| The adaptor protein Nck links receptor tyrosine kinases with the serine-threonine kinase Pak1 | Q28289174 | ||
| Proline-rich tyrosine kinase 2 regulates osteoprogenitor cells and bone formation, and offers an anabolic treatment approach for osteoporosis | Q28507090 | ||
| Dissecting activation of the PAK1 kinase at protrusions in living cells | Q28576912 | ||
| Thrombin induces expression of FGF-2 via activation of PI3K-Akt-Fra-1 signaling axis leading to DNA synthesis and motility in vascular smooth muscle cells | Q28581725 | ||
| Rho and Rac take center stage | Q28645748 | ||
| Inflammation, atherosclerosis, and coronary artery disease | Q29547232 | ||
| Heart disease and stroke statistics--2011 update: a report from the American Heart Association | Q29547236 | ||
| GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors | Q29547630 | ||
| Biology of the p21-activated kinases | Q29616035 | ||
| Progress and challenges in translating the biology of atherosclerosis | Q29619982 | ||
| To stabilize neutrophil polarity, PIP3 and Cdc42 augment RhoA activity at the back as well as signals at the front | Q30480454 | ||
| Regulation of myosin activation during cell-cell contact formation by Par3-Lgl antagonism: entosis without matrix detachment | Q30514271 | ||
| Signal transduction involved in MCP-1-mediated monocytic transendothelial migration | Q31819029 | ||
| Low density lipoprotein receptor-related protein (LRP1) regulates Rac1 and RhoA reciprocally to control Schwann cell adhesion and migration | Q33824976 | ||
| Distinct recruitment and function of Gab1 and Gab2 in Met receptor-mediated epithelial morphogenesis | Q33899291 | ||
| G13alpha-mediated PYK2 activation. PYK2 is a mediator of G13alpha -induced serum response element-dependent transcription. | Q33902691 | ||
| Proteinase-activated receptors. | Q33947141 | ||
| Identification of MCM4 as a Target of the DNA Replication Block Checkpoint System | Q34192831 | ||
| Protease activated receptors: theme and variations | Q34225983 | ||
| Membrane targeting of Grb2-associated binder-1 (Gab1) scaffolding protein through Src myristoylation sequence substitutes for Gab1 pleckstrin homology domain and switches an epidermal growth factor response to an invasive morphogenic program | Q34926469 | ||
| The "Gab" in signal transduction. | Q35082143 | ||
| Protease-activated receptors: new concepts in regulation of G protein-coupled receptor signaling and trafficking | Q35215957 | ||
| Development of Proteinase-Activated Receptor 1 Antagonists as Therapeutic Agents for Thrombosis, Restenosis and Inflammatory Diseases | Q35551904 | ||
| Thrombin receptor expression in normal and atherosclerotic human arteries | Q35607594 | ||
| The genetics of Pak. | Q35872596 | ||
| Activation of p115-RhoGEF requires direct association of Gα13 and the Dbl homology domain | Q36127073 | ||
| Protease-activated receptors in hemostasis, thrombosis and vascular biology | Q36230881 | ||
| The tyrosine phosphatase SHP2 regulates recovery of endothelial adherens junctions through control of β-catenin phosphorylation | Q36356541 | ||
| Scaffolding protein Grb2-associated binder 1 sustains epidermal growth factor-induced mitogenic and survival signaling by multiple positive feedback loops | Q36559220 | ||
| Catching a GEF by its tail | Q36663439 | ||
| PDZ-RhoGEF and LARG are essential for embryonic development and provide a link between thrombin and LPA receptors and Rho activation | Q36796926 | ||
| CD36 modulates migration of mouse and human macrophages in response to oxidized LDL and may contribute to macrophage trapping in the arterial intima | Q37036080 | ||
| KDR stimulates endothelial cell migration through heterotrimeric G protein Gq/11-mediated activation of a small GTPase RhoA. | Q38362761 | ||
| GPCR activation of Ras and PI3Kc in neutrophils depends on PLCb2/b3 and the RasGEF RasGRP4. | Q39326099 | ||
| The structure of the macrophage actin skeleton | Q39338615 | ||
| Signals from the Ras, Rac, and Rho GTPases converge on the Pak protein kinase in Rat-1 fibroblasts | Q39444795 | ||
| G alpha 12 inhibits alpha2 beta1 integrin-mediated Madin-Darby canine kidney cell attachment and migration on collagen-I and blocks tubulogenesis | Q39795915 | ||
| Specificity and mechanism of action of EHT 1864, a novel small molecule inhibitor of Rac family small GTPases. | Q40068834 | ||
| Macrophage colony-stimulating factor rapidly enhances beta-migrating very low density lipoprotein metabolism in macrophages through activation of a Gi/o protein signaling pathway | Q40858069 | ||
| Thrombin promotes actin polymerization in U937 human monocyte-macrophage cells. Analysis of the signalling mechanisms mediating actin polymerization | Q41603026 | ||
| Rho and Rho kinase mediate thrombin-stimulated vascular smooth muscle cell DNA synthesis and migration | Q41668247 | ||
| Novel role of proline-rich nonreceptor tyrosine kinase 2 in vascular wall remodeling after balloon injury | Q41859541 | ||
| A role for Gab1/SHP2 in thrombin activation of PAK1: gene transfer of kinase-dead PAK1 inhibits injury-induced restenosis | Q42926016 | ||
| The p38 mitogen-activated protein kinase pathway plays a critical role in thrombin-induced endothelial chemokine production and leukocyte recruitment | Q43684711 | ||
| Common signaling pathways link activation of murine PAR-1, LPA, and S1P receptors to proliferation of astrocytes. | Q44628572 | ||
| Involvement of phosphoinositide 3-kinase gamma, Rac, and PAK signaling in chemokine-induced macrophage migration | Q45005871 | ||
| Thrombin induces long-term potentiation of reactivity to afferent stimulation and facilitates epileptic seizures in rat hippocampal slices: toward understanding the functional consequences of cerebrovascular insults. | Q46804891 | ||
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P433 | issue | 43 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | cell migration | Q189092 |
| P1104 | number of pages | 17 | |
| P304 | page(s) | 30815-30831 | |
| P577 | publication date | 2013-09-11 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Novel role for p21-activated kinase 2 in thrombin-induced monocyte migration | |
| P478 | volume | 288 |
| Q39724484 | Angiopoietin-2 mediates thrombin-induced monocyte adhesion and endothelial permeability |
| Q94544490 | CX3CL1 Induces Vertebral Microvascular Barrier Dysfunction via the Src/P115-RhoGEF/ROCK Signaling Pathway |
| Q33809148 | Gastrointestinal hormones/neurotransmitters and growth factors can activate P21 activated kinase 2 in pancreatic acinar cells by novel mechanisms |
| Q96640278 | Gα12/13 signaling in metabolic diseases |
| Q91907118 | Long non-coding RNA ZEB1-AS1 promotes colon adenocarcinoma malignant progression via miR-455-3p/PAK2 axis |
| Q34120393 | Motility of select ovarian cancer cell lines: effect of extra-cellular matrix proteins and the involvement of PAK2 |
| Q64271833 | P21 activated kinase 2 promotes pancreatic cancer growth and metastasis |
| Q28274555 | P21-activated kinase 2 (PAK2) regulates glucose uptake and insulin sensitivity in neuronal cells |
| Q34032604 | P21-activated kinase in inflammatory and cardiovascular disease |
| Q41941690 | PTEN plays an important role in thrombin-mediated lung cancer cell functions |
| Q26823650 | Phosphorylation-mediated regulation of GEFs for RhoA |
| Q38262626 | Protease activated receptor-1 regulates macrophage-mediated cellular senescence: a risk for idiopathic pulmonary fibrosis |
| Q88732568 | Protease-activated receptor 1 inhibits cholesterol efflux and promotes atherogenesis via cullin 3-mediated degradation of the ABCA1 transporter |
| Q89506730 | Protein Kinase Cθ Via Activating Transcription Factor 2-Mediated CD36 Expression and Foam Cell Formation of Ly6Chi Cells Contributes to Atherosclerosis |
| Q40792797 | Rac1 regulates bacterial toxin-induced thrombin generation |
| Q40464595 | Scaffolding protein Gab1 regulates myeloid dendritic cell migration in allergic asthma. |
| Q38224525 | Sphingosine 1-phosphate as a link between blood coagulation and inflammation |
| Q39024744 | Targeting coagulation factor receptors - protease-activated receptors in idiopathic pulmonary fibrosis |
| Q35216552 | The Role of Thrombin and Cell Contractility in Regulating Clustering and Collective Migration of Corneal Fibroblasts in Different ECM Environments |
| Q104790197 | Thrombin generation and activity in multiple sclerosis |
| Q37709136 | Thrombin inhibition and cisplatin block tumor progression in ovarian cancer by alleviating the immunosuppressive microenvironment |
| Q92569861 | Thrombin stimulates gene expression and secretion of IL-11 via protease-activated receptor-1 and regulates extravillous trophoblast cell migration |
| Q89741064 | Transcriptomic and functional studies reveal undermined chemotactic and angiostimulatory properties of aged microglia during stroke recovery |
| Q90336791 | miR-26a inhibits proliferation and promotes apoptosis in porcine immature Sertoli cells by targeting the PAK2 gene |
| Q36825803 | p21-activated kinase 2 regulates HSPC cytoskeleton, migration, and homing via CDC42 activation and interaction with β-Pix |
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