Ptc1 protein phosphatase 2C contributes to glucose regulation of SNF1/AMP-activated protein kinase (AMPK) in Saccharomyces cerevisiae

scientific article published on 09 September 2013

Ptc1 protein phosphatase 2C contributes to glucose regulation of SNF1/AMP-activated protein kinase (AMPK) in Saccharomyces cerevisiae is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M113.503763
P932PMC publication ID3829418
P698PubMed publication ID24019512

P2093author name stringMarian Carlson
Amparo Ruiz
Xinjing Xu
P2860cites workDissecting the role of 5'-AMP for allosteric stimulation, activation, and deactivation of AMP-activated protein kinaseQ50337120
A constraint network of interactions: protein-protein interaction analysis of the yeast type II phosphatase Ptc1p and its adaptor protein Nbp2p.Q53286334
Transcriptional Profiling of the Protein Phosphatase 2C Family in Yeast Provides Insights into the Unique Functional Roles of Ptc1Q61807883
Role of protein phosphatases 2C on tolerance to lithium toxicity in the yeast Saccharomyces cerevisiaeQ80221202
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Ppm1E is an in cellulo AMP-activated protein kinase phosphataseQ24297838
AMP-activated protein kinase: an energy sensor that regulates all aspects of cell functionQ26865723
ADP Regulates SNF1, the Saccharomyces cerevisiae Homolog of AMP-Activated Protein KinaseQ27675159
A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiaeQ27860636
Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysisQ27860815
Regulation of Snf1 kinase. Activation requires phosphorylation of threonine 210 by an upstream kinase as well as a distinct step mediated by the Snf4 subunitQ27931918
Nutrients, via the Tor proteins, stimulate the association of Tap42 with type 2A phosphatasesQ27932611
Mutational analysis of the Saccharomyces cerevisiae SNF1 protein kinase and evidence for functional interaction with the SNF4 proteinQ27932928
Identification of multicopy suppressors of cell cycle arrest at the G1-S transition in Saccharomyces cerevisiae.Q27935361
Yeast SNF1 is functionally related to mammalian AMP-activated protein kinase and regulates acetyl-CoA carboxylase in vivo.Q27936729
The SAP, a new family of proteins, associate and function positively with the SIT4 phosphataseQ27938022
The SIT4 protein phosphatase functions in late G1 for progression into S phaseQ27938661
A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vectorQ28131601
Regulatory interactions between the Reg1-Glc7 protein phosphatase and the Snf1 protein kinaseQ30453592
Snf1p regulates Gcn5p transcriptional activity by antagonizing Spt3pQ33628559
Snf1 promotes phosphorylation of the alpha subunit of eukaryotic translation initiation factor 2 by activating Gcn2 and inhibiting phosphatases Glc7 and Sit4.Q33877596
Roles of two protein phosphatases, Reg1-Glc7 and Sit4, and glycogen synthesis in regulation of SNF1 protein kinaseQ34836353
Alterations at dispersed sites cause phosphorylation and activation of SNF1 protein kinase during growth on high glucoseQ35067886
Ubp8 and SAGA regulate Snf1 AMP kinase activity.Q35139409
New 'marker swap' plasmids for converting selectable markers on budding yeast gene disruptions and plasmidsQ35191795
Access denied: Snf1 activation loop phosphorylation is controlled by availability of the phosphorylated threonine 210 to the PP1 phosphataseQ35630441
Subunit and domain requirements for adenylate-mediated protection of Snf1 kinase activation loop from dephosphorylationQ35639796
Heterotrimer-independent regulation of activation-loop phosphorylation of Snf1 protein kinase involves two protein phosphatasesQ36001396
SNF1/AMPK pathways in yeastQ36992466
Glucose-regulated interaction of a regulatory subunit of protein phosphatase 1 with the Snf1 protein kinase in Saccharomyces cerevisiaeQ37393837
Type 2C protein phosphatases in fungiQ37809415
Normal function of the yeast TOR pathway requires the type 2C protein phosphatase Ptc1.Q38356043
The PP1-R6 protein phosphatase holoenzyme is involved in the glucose-induced dephosphorylation and inactivation of AMP-activated protein kinase, a key regulator of insulin secretion, in MIN6 beta cellsQ39665473
The ubiquitin-associated domain of AMPK-related kinases regulates conformation and LKB1-mediated phosphorylation and activationQ40333412
REG1 binds to protein phosphatase type 1 and regulates glucose repression in Saccharomyces cerevisiae.Q40790102
Interaction of SNF1 protein kinase with its activating kinase Sak1.Q42023558
Investigating the mechanism for AMP activation of the AMP-activated protein kinase cascadeQ42160057
Functional overlap and regulatory links shape genetic interactions between signaling pathways.Q42713526
Function of mammalian LKB1 and Ca2+/calmodulin-dependent protein kinase kinase alpha as Snf1-activating kinases in yeastQ46438638
P4510describes a project that usesImageJQ1659584
P433issue43
P407language of work or nameEnglishQ1860
P921main subjectglucoseQ37525
Saccharomyces cerevisiaeQ719725
P304page(s)31052-31058
P577publication date2013-09-09
P1433published inJournal of Biological ChemistryQ867727
P1476titlePtc1 protein phosphatase 2C contributes to glucose regulation of SNF1/AMP-activated protein kinase (AMPK) in Saccharomyces cerevisiae
P478volume288

Reverse relations

cites work (P2860)
Q30394876AMPK in Yeast: The SNF1 (Sucrose Non-fermenting 1) Protein Kinase Complex
Q36090408Cross-Talk between Carbon Metabolism and the DNA Damage Response in S. cerevisiae
Q35860533Feedback Control of Snf1 Protein and Its Phosphorylation Is Necessary for Adaptation to Environmental Stress
Q99404632Fine-Tuning of Energy Levels Regulates SUC2 via a SNF1-Dependent Feedback Loop
Q51111713Glucose de-repression by yeast AMP-activated protein kinase SNF1 is controlled via at least two independent steps.
Q38218118Mechanisms of regulation of SNF1/AMPK/SnRK1 protein kinases
Q99572208Mig1 localization exhibits biphasic behavior which is controlled by both metabolic and regulatory roles of the sugar kinases
Q47650414Mitochondrial Voltage-Dependent Anion Channel Protein Por1 Positively Regulates the Nuclear Localization of Saccharomyces cerevisiae AMP-Activated Protein Kinase
Q38494538Molecular communication: crosstalk between the Snf1 and other signaling pathways
Q34548962Nutrient sensing and signaling in the yeast Saccharomyces cerevisiae
Q42987213Phosphatases Generate Signal Specificity Downstream of Ssp1 Kinase in Fission Yeast
Q27935716Protein kinase Snf1 is involved in the proper regulation of the unfolded protein response in Saccharomyces cerevisiae
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Q39772044SUMOylation represses SnRK1 signaling in Arabidopsis.
Q64094867Ser/Thr protein phosphatases in fungi: structure, regulation and function
Q39774166The Saccharomyces cerevisiae Ptc1 protein phosphatase attenuates G2-M cell cycle blockage caused by activation of the cell wall integrity pathway.
Q39011337The plant energy sensor: evolutionary conservation and divergence of SnRK1 structure, regulation, and function
Q51328031Trehalose-6-phosphate synthesis controls yeast gluconeogenesis downstream and independent of SNF1.
Q42040234Wide-Ranging Effects of the Yeast Ptc1 Protein Phosphatase Acting Through the MAPK Kinase Mkk1.