Retina-specific GTPase accelerator RGS11/G beta 5S/R9AP is a constitutive heterotrimer selectively targeted to mGluR6 in ON-bipolar neurons

scientific article published on July 2009

Retina-specific GTPase accelerator RGS11/G beta 5S/R9AP is a constitutive heterotrimer selectively targeted to mGluR6 in ON-bipolar neurons is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1523/JNEUROSCI.1367-09.2009
P932PMC publication ID2731308
P698PubMed publication ID19625520
P5875ResearchGate publication ID26688976

P50authorAlapakkam P SampathQ89219213
P2093author name stringPaul J Kammermeier
Yan Cao
Takahisa Furukawa
Kirill A Martemyanov
Takayoshi Inoue
Ikuo Masuho
Haruhisa Okawa
Dennis M Maddox
Junko Asami
Keqiang Xie
P2860cites workA G protein γ subunit-like domain shared between RGS11 and other RGS proteins specifies binding to G β5 subunitsQ22004020
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Neurochemical organization of the first visual synapseQ78350880
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R7BP, a novel neuronal protein interacting with RGS proteins of the R7 familyQ81230034
Controlling the gain of rod-mediated signals in the Mammalian retinaQ83150052
The DEP Domain Determines Subcellular Targeting of the GTPase Activating Protein RGS9In VivoQ28183847
RGS9-2 is a negative modulator of mu-opioid receptor functionQ28242513
A role of RGS proteins in drug addictionQ28249710
Regulators of G-Protein Signaling (RGS) Proteins: Region-Specific Expression of Nine Subtypes in Rat BrainQ28250219
Absence of the RGS9.Gbeta5 GTPase-activating complex in photoreceptors of the R9AP knockout mouseQ28505673
Pikachurin, a dystroglycan ligand, is essential for photoreceptor ribbon synapse formationQ28507319
Palmitoylation regulates plasma membrane-nuclear shuttling of R7BP, a novel membrane anchor for the RGS7 familyQ28512296
The GTPase activating factor for transducin in rod photoreceptors is the complex between RGS9 and type 5 G protein beta subunitQ28609908
Cellular regulation of RGS proteins: modulators and integrators of G protein signalingQ28646133
RIBEYE, a Component of Synaptic RibbonsQ29540824
Expression patterns of the RGS9-1 anchoring protein R9AP in the chicken and mouse suggest multiple roles in the nervous systemQ31031856
Targeting of RGS7/Gbeta5 to the dendritic tips of ON-bipolar cells is independent of its association with membrane anchor R7BP.Q33374783
The light response of ON bipolar neurons requires G[alpha]o.Q33928816
D2 dopamine receptors colocalize regulator of G-protein signaling 9-2 (RGS9-2) via the RGS9 DEP domain, and RGS9 knock-out mice develop dyskinesias associated with dopamine pathways.Q34397299
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Gbeta5-RGS complexes co-localize with mGluR6 in retinal ON-bipolar cellsQ36731468
Optimization of single-photon response transmission at the rod-to-rod bipolar synapseQ36910759
The outer segment serves as a default destination for the trafficking of membrane proteins in photoreceptorsQ36955713
Regulation of ON bipolar cell activity.Q37077529
Generation, identification and functional characterization of the nob4 mutation of Grm6 in the mouse.Q37164641
The membrane anchor R7BP controls the proteolytic stability of the striatal specific RGS protein, RGS9-2.Q40198648
Subcellular targeting of RGS9-2 is controlled by multiple molecular determinants on its membrane anchor, R7BP.Q40297867
A retinal-specific regulator of G-protein signaling interacts with Galpha(o) and accelerates an expressed metabotropic glutamate receptor 6 cascade.Q40541998
RGS6, RGS7, RGS9, and RGS11 stimulate GTPase activity of Gi family G-proteins with differential selectivity and maximal activityQ42049270
Neurochemistry of the mammalian cone `synaptic complex'Q42458303
Assay of RGS Protein Activity in Vitro Using Purified ComponentsQ43842122
Types of bipolar cells in the mouse retinaQ44702170
Gbeta5 is required for normal light responses and morphology of retinal ON-bipolar cells.Q44934687
Cell communication mechanisms in the vertebrate retina the proctor lectureQ46226287
Allelic variance between GRM6 mutants, Grm6nob3 and Grm6nob4 results in differences in retinal ganglion cell visual responsesQ46440209
Recoverin improves rod-mediated vision by enhancing signal transmission in the mouse retinaQ46480734
Expression and localization of RGS9-2/G 5/R7BP complex in vivo is set by dynamic control of its constitutive degradation by cellular cysteine proteases.Q46840630
Cadherin-6 in the developing mouse brain: Expression along restricted connection systems and synaptic localization suggest a potential role in neuronal circuitryQ48479674
Identification and characterization of alternatively spliced murine Rgs11 isoforms: genomic structure and gene analysisQ48682368
Specific deficit of the ON response in visual transmission by targeted disruption of the mGluR6 geneQ52511684
Suppression by glutamate of cGMP-activated conductance in retinal bipolar cellsQ59081517
Glutamate receptors of rod bipolar cells are linked to a cyclic GMP cascade via a G-proteinQ67684264
Developmentally regulated postsynaptic localization of a metabotropic glutamate receptor in rat rod bipolar cellsQ72414967
RGS9-G beta 5 substrate selectivity in photoreceptors. Opposing effects of constituent domains yield high affinity of RGS interaction with the G protein-effector complexQ74338873
Identification of the Gβ5-RGS7 Protein Complex in the RetinaQ77219490
The metabotropic receptor mGluR6 may signal through G(o), but not phosphodiesterase, in retinal bipolar cellsQ77223746
P4510describes a project that usesImageQuantQ112270642
P433issue29
P407language of work or nameEnglishQ1860
P304page(s)9301-9313
P577publication date2009-07-01
P1433published inJournal of NeuroscienceQ1709864
P1476titleRetina-specific GTPase accelerator RGS11/G beta 5S/R9AP is a constitutive heterotrimer selectively targeted to mGluR6 in ON-bipolar neurons
P478volume29

Reverse relations

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