RGS9-G beta 5 substrate selectivity in photoreceptors. Opposing effects of constituent domains yield high affinity of RGS interaction with the G protein-effector complex

scientific article published on 08 August 2001

RGS9-G beta 5 substrate selectivity in photoreceptors. Opposing effects of constituent domains yield high affinity of RGS interaction with the G protein-effector complex is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M106431200
P698PubMed publication ID11495924

P2093author name stringA Bohm
N P Skiba
V Y Arshavsky
W F Simonds
A Elfenbein
J A Hopp
K A Martemyanov
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Flow of information in the light-triggered cyclic nucleotide cascade of visionQ24635148
Gbeta5 prevents the RGS7-Galphao interaction through binding to a distinct Ggamma-like domain found in RGS7 and other RGS proteinsQ24644618
Structural basis of the recognition of the dishevelled DEP domain in the Wnt signaling pathwayQ27628766
Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 AQ27630282
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Regulators of G protein signaling 6 and 7. Purification of complexes with gbeta5 and assessment of their effects on g protein-mediated signaling pathwaysQ28116135
RGS7 is palmitoylated and exists as biochemically distinct formsQ28141269
GTPase-activating proteins for heterotrimeric G proteins: regulators of G protein signaling (RGS) and RGS-like proteinsQ28145018
The regulator of G protein signaling familyQ28145604
A novel form of the G protein β Subunit Gβ5 is specifically expressed in the vertebrate retinaQ28296250
Complexes of the G protein subunit gbeta 5 with the regulators of G protein signaling RGS7 and RGS9. Characterization in native tissues and in transfected cellsQ28583318
The GTPase activating factor for transducin in rod photoreceptors is the complex between RGS9 and type 5 G protein beta subunitQ28609908
RGS9, a GTPase accelerator for phototransductionQ28610017
Regulators of G Protein SignalingQ29302980
Prediction and confirmation of a site critical for effector regulation of RGS domain activityQ32063831
RGS proteins: lessons from the RGS9 subfamilyQ34047832
Ggamma-like (GGL) domains: new frontiers in G-protein signaling and beta-propeller scaffolding.Q34237416
Activation of the retinal cGMP-specific phosphodiesterase by the GDP-loaded alpha-subunit of transducin.Q34338398
Characterization and analysis of frog photoreceptor membranesQ36428494
Lifetime regulation of G protein-effector complex: emerging importance of RGS proteinsQ41698565
RGS7 complex formation and colocalization with the Gbeta5 subunit in the adult rat brain and influence on Gbeta5gamma2-mediated PLCbeta signalingQ42485202
Pleckstrin's repeat performance: a novel domain in G-protein signaling?Q48062692
Regulation of deactivation of photoreceptor G protein by its target enzyme and cGMPQ59075084
The isolation and purification of osmotically intact discs from retinal rod outer segmentsQ66893499
Transducin GTPase provides for rapid quenching of the cGMP cascade in rod outer segmentsQ69353138
A GTPase-accelerating factor for transducin, distinct from its effector cGMP phosphodiesterase, in rod outer segment membranesQ72608788
Activation of transducin guanosine triphosphatase by two proteins of the RGS familyQ73456091
Enzymology of GTPase acceleration in phototransductionQ73591669
Rapid kinetics of regulator of G-protein signaling (RGS)-mediated Galphai and Galphao deactivation. Galpha specificity of RGS4 AND RGS7Q74172895
The effector enzyme regulates the duration of G protein signaling in vertebrate photoreceptors by increasing the affinity between transducin and RGS proteinQ74270254
Modules in the photoreceptor RGS9-1.Gbeta 5L GTPase-accelerating protein complex control effector coupling, GTPase acceleration, protein folding, and stabilityQ74291097
The alpha-helical domain of Galphat determines specific interaction with regulator of G protein signaling 9Q74620373
Identification of the Gbeta5-RGS7 protein complex in the retinaQ77219490
Modulation of transducin GTPase activity by chimeric RGS16 and RGS9 regulators of G protein signaling and the effector moleculeQ77357796
P433issue40
P407language of work or nameEnglishQ1860
P1104number of pages8
P304page(s)37365-37372
P577publication date2001-08-08
P1433published inJournal of Biological ChemistryQ867727
P1476titleRGS9-G beta 5 substrate selectivity in photoreceptors. Opposing effects of constituent domains yield high affinity of RGS interaction with the G protein-effector complex
P478volume276

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cites work (P2860)
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