An N-terminal region of Caenorhabditis elegans RGS proteins EGL-10 and EAT-16 directs inhibition of G(alpha)o versus G(alpha)q signaling

scientific article published on 26 September 2002

An N-terminal region of Caenorhabditis elegans RGS proteins EGL-10 and EAT-16 directs inhibition of G(alpha)o versus G(alpha)q signaling is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.M208186200
P698PubMed publication ID12354761

P2093author name stringMichael R Koelle
Georgia A Patikoglou
P2860cites workSlowed recovery of rod photoresponse in mice lacking the GTPase accelerating protein RGS9-1.Q41719683
Modulation of serotonin-controlled behaviors by Go in Caenorhabditis elegansQ43327212
Specific binding of RGS9-Gbeta 5L to protein anchor in photoreceptor membranes greatly enhances its catalytic activityQ43990174
Participation of the protein Go in multiple aspects of behavior in C. elegansQ46831533
Two RGS proteins that inhibit Galpha(o) and Galpha(q) signaling in C. elegans neurons require a Gbeta(5)-like subunit for functionQ47068883
Regulators of G protein signaling proteins as determinants of the rate of desensitization of presynaptic calcium channelsQ47966163
Pleckstrin's repeat performance: a novel domain in G-protein signaling?Q48062692
Modules in the photoreceptor RGS9-1.Gbeta 5L GTPase-accelerating protein complex control effector coupling, GTPase acceleration, protein folding, and stabilityQ74291097
RGS9-G beta 5 substrate selectivity in photoreceptors. Opposing effects of constituent domains yield high affinity of RGS interaction with the G protein-effector complexQ74338873
A G protein γ subunit-like domain shared between RGS11 and other RGS proteins specifies binding to G β5 subunitsQ22004020
R9AP, a membrane anchor for the photoreceptor GTPase accelerating protein, RGS9-1Q24533588
RGS2/G0S8 is a selective inhibitor of Gqα functionQ24648296
The regulators of G protein signaling (RGS) domains of RGS4, RGS10, and GAIP retain GTPase activating protein activity in vitroQ24655997
Structure of RGS4 bound to AlF4--activated G(i alpha1): stabilization of the transition state for GTP hydrolysisQ27736041
Regulators of G protein signaling 6 and 7. Purification of complexes with gbeta5 and assessment of their effects on g protein-mediated signaling pathwaysQ28116135
GTPase-activating proteins for heterotrimeric G proteins: regulators of G protein signaling (RGS) and RGS-like proteinsQ28145018
RGS7 Attenuates Signal Transduction Through the Gαq Family of Heterotrimeric G Proteins in Mammalian CellsQ28269732
EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteinsQ28272431
GAIP and RGS4 are GTPase-activating proteins for the Gi subfamily of G protein alpha subunitsQ28286818
RGS9, a GTPase accelerator for phototransductionQ28610017
Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathwaysQ28616373
DNA transformationQ29616766
Antagonism between G(o)alpha and G(q)alpha in Caenorhabditis elegans: the RGS protein EAT-16 is necessary for G(o)alpha signaling and regulates G(q)alpha activityQ35201877
Mutations in a C. elegans Gqalpha gene disrupt movement, egg laying, and viability.Q35650374
Attenuation of Gi- and Gq-mediated signaling by expression of RGS4 or GAIP in mammalian cellsQ36180412
Endoproteolytic processing of Sst2, a multidomain regulator of G protein signaling in yeastQ38308460
P433issue49
P407language of work or nameEnglishQ1860
P921main subjectCaenorhabditis elegansQ91703
P304page(s)47004-47013
P577publication date2002-09-26
P1433published inJournal of Biological ChemistryQ867727
P1476titleAn N-terminal region of Caenorhabditis elegans RGS proteins EGL-10 and EAT-16 directs inhibition of G(alpha)o versus G(alpha)q signaling
P478volume277

Reverse relations

cites work (P2860)
Q35180330AGS-3 AltersCaenorhabditis elegansBehavior after Food Deprivation via RIC-8 Activation of the Neural G Protein Gαo
Q28469000Chemical genetics reveals an RGS/G-protein role in the action of a compound
Q36085676Chemistry-to-gene screens in Caenorhabditis elegans
Q27649555Crystal structure of the multifunctional Gβ5–RGS9 complex
Q40618796Differentially Regulated Expression of Endogenous RGS4 and RGS7
Q40737692Evidence for a role of the regulator of G-protein signaling protein CPRGS-1 in Galpha subunit CPG-1-mediated regulation of fungal virulence, conidiation, and hydrophobin synthesis in the chestnut blight fungus Cryphonectria parasitica
Q47069082G protein-coupled receptor kinase-2 (GRK-2) regulates serotonin metabolism through the monoamine oxidase AMX-2 in Caenorhabditis elegans
Q35864245Genetic analysis of RGS protein function in Caenorhabditis elegans
Q37726386Identification of ligands targeting RGS proteins high-throughput screening and therapeutic potential
Q35756131Identifying components of protein complexes in C. elegans using co-immunoprecipitation and mass spectrometry
Q37726350Insights into RGS protein function from studies in Caenorhabditis elegans
Q50626616Lifespan extension and increased pumping rate accompany pharyngeal muscle-specific expression of nfi-1 in C. elegans
Q42490242Modulation of dopamine‐dependent behaviors by the Caenorhabditis elegans Olig homolog HLH‐17
Q41881375Molecular organization of the complex between the muscarinic M3 receptor and the regulator of G protein signaling, Gbeta(5)-RGS7.
Q41011634Neurotransmitter signaling through heterotrimeric G proteins: insights from studies in C. elegans
Q47756471Nuclear PKG localization is regulated by Go alpha and is necessary in the AWB neurons to mediate avoidance in Caenorhabditis elegans
Q24681161PI3K regulates pleckstrin-2 in T-cell cytoskeletal reorganization.
Q46979976Presynaptic Ca2+/calmodulin-dependent protein kinase II modulates neurotransmitter release by activating BK channels at Caenorhabditis elegans neuromuscular junction.
Q40503603Purification and in vitro functional analysis of R7 subfamily RGS proteins in complex with Gbeta5.
Q37337611R9AP and R7BP: traffic cops for the RGS7 family in phototransduction and neuronal GPCR signaling
Q30492826RSBP-1 is a membrane-targeting subunit required by the Galpha(q)-specific but not the Galpha(o)-specific R7 regulator of G protein signaling in Caenorhabditis elegans
Q38706526Regulation of neurite morphogenesis by interaction between R7 regulator of G protein signaling complexes and G protein subunit Gα13.
Q37726364Structure, function, and localization of Gβ5-RGS complexes
Q28183847The DEP Domain Determines Subcellular Targeting of the GTPase Activating Protein RGS9In Vivo
Q33744428The G protein regulators EGL-10 and EAT-16, the Giα GOA-1 and the G(q)α EGL-30 modulate the response of the C. elegans ASH polymodal nociceptive sensory neurons to repellents
Q24606708Type 5 G Protein β Subunit (Gβ5) Controls the Interaction of Regulator of G Protein Signaling 9 (RGS9) with Membrane Anchors

Search more.