R9AP and R7BP: traffic cops for the RGS7 family in phototransduction and neuronal GPCR signaling

scientific article

R9AP and R7BP: traffic cops for the RGS7 family in phototransduction and neuronal GPCR signaling is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.TIPS.2008.10.002
P932PMC publication ID2776672
P698PubMed publication ID19042037
P5875ResearchGate publication ID23554998

P2093author name stringHao Zhou
Kendall J Blumer
Matthew D Cain
Muralidharan Jayaraman
Lixia Jia
P2860cites workSix Patients with Bradyopsia (Slow Vision)Q24262222
Generation and characterization of Rgs4 mutant miceQ24523661
R9AP, a membrane anchor for the photoreceptor GTPase accelerating protein, RGS9-1Q24533588
High expression levels in cones of RGS9, the predominant GTPase accelerating protein of rodsQ24569573
Motor coordination deficits in mice lacking RGS9Q24648527
Essential role for RGS9 in opiate actionQ24655663
Instability of GGL domain-containing RGS proteins in mice lacking the G protein beta-subunit Gbeta5Q24670878
Crystal structure of the multifunctional Gβ5–RGS9 complexQ27649555
Regulators of G protein signaling 6 and 7. Purification of complexes with gbeta5 and assessment of their effects on g protein-mediated signaling pathwaysQ28116135
RGS7 is palmitoylated and exists as biochemically distinct formsQ28141269
Nuclear localization of G protein beta 5 and regulator of G protein signaling 7 in neurons and brainQ28142336
GTPase-activating proteins for heterotrimeric G proteins: regulators of G protein signaling (RGS) and RGS-like proteinsQ28145018
The DEP Domain Determines Subcellular Targeting of the GTPase Activating Protein RGS9In VivoQ28183847
G beta 5.RGS7 inhibits G alpha q-mediated signaling via a direct protein-protein interactionQ28188095
Defects in RGS9 or its anchor protein R9AP in patients with slow photoreceptor deactivationQ28236836
A role of RGS proteins in drug addictionQ28249710
Regulators of G-Protein Signaling (RGS) Proteins: Region-Specific Expression of Nine Subtypes in Rat BrainQ28250219
R7BP augments the function of RGS7*Gbeta5 complexes by a plasma membrane-targeting mechanismQ28254091
Palmitoylation of intracellular signaling proteins: regulation and functionQ28266189
Identification of small-molecule inhibitors of RGS4 using a high-throughput flow cytometry protein interaction assayQ28266287
EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteinsQ28272431
Goalpha regulates volatile anesthetic action in Caenorhabditis elegansQ28366737
Absence of the RGS9.Gbeta5 GTPase-activating complex in photoreceptors of the R9AP knockout mouseQ28505673
Palmitoylation regulates plasma membrane-nuclear shuttling of R7BP, a novel membrane anchor for the RGS7 familyQ28512296
Differential expression of the regulator of G protein signaling RGS9 protein in nociceptive pathways of different age ratsQ28577511
RGS9-2 modulates D2 dopamine receptor-mediated Ca2+ channel inhibition in rat striatal cholinergic interneuronsQ28578625
Brain-specific RGS9-2 is localized to the nucleus via its unique proline-rich domainQ28580061
Complexes of the G protein subunit gbeta 5 with the regulators of G protein signaling RGS7 and RGS9. Characterization in native tissues and in transfected cellsQ28583318
The GTPase activating factor for transducin in rod photoreceptors is the complex between RGS9 and type 5 G protein beta subunitQ28609908
RGS9, a GTPase accelerator for phototransductionQ28610017
Cellular regulation of RGS proteins: modulators and integrators of G protein signalingQ28646133
Cloning and characterization of RGS9-2: a striatal-enriched alternatively spliced product of the RGS9 geneQ30653116
Copurification of brain G-protein beta5 with RGS6 and RGS7.Q30834724
Expression patterns of the RGS9-1 anchoring protein R9AP in the chicken and mouse suggest multiple roles in the nervous systemQ31031856
RGS9: A regulator of G-protein signalling with specific expression in rat and mouse striatumQ32066784
Ethnic stratification of the association of RGS4 variants with antipsychotic treatment response in schizophrenia.Q33288672
SNAREs and the specificity of membrane fusionQ34221149
D2 dopamine receptors colocalize regulator of G-protein signaling 9-2 (RGS9-2) via the RGS9 DEP domain, and RGS9 knock-out mice develop dyskinesias associated with dopamine pathways.Q34397299
Psychosis pathways converge via D2high dopamine receptorsQ34540180
The loss of the PDE6 deactivating enzyme, RGS9, results in precocious light adaptation at low light levelsQ34758194
Regulators of G protein signaling (RGS proteins): novel central nervous system drug targetsQ35015775
Pleiotropic phenotype of a genomic knock-in of an RGS-insensitive G184S Gnai2 alleleQ35071259
Antagonism between G(o)alpha and G(q)alpha in Caenorhabditis elegans: the RGS protein EAT-16 is necessary for G(o)alpha signaling and regulates G(q)alpha activityQ35201877
Desensitization of G protein-coupled receptors and neuronal functionsQ35817048
RGS-insensitive G-protein mutations to study the role of endogenous RGS proteinsQ35864233
Regulators of G protein signaling & drugs of abuse.Q36056317
Mechanisms of vertebrate synaptogenesisQ36196530
Postnatal induction and localization of R7BP, a membrane-anchoring protein for regulator of G protein signaling 7 family-Gbeta5 complexes in brainQ36539488
A role for rhodopsin in a signal transduction cascade that regulates membrane trafficking and photoreceptor polarityQ36607636
Gbeta5-RGS complexes co-localize with mGluR6 in retinal ON-bipolar cellsQ36731468
Pharmacogenomics of G protein-coupled receptor signaling: insights from health and diseaseQ37120554
Intramolecular interaction between the DEP domain of RGS7 and the Gbeta5 subunitQ38301611
Olanzapine increases RGS7 protein expression via stimulation of the Janus tyrosine kinase-signal transducer and activator of transcription signaling cascade.Q40152916
Subcellular targeting of RGS9-2 is controlled by multiple molecular determinants on its membrane anchor, R7BP.Q40297867
Slowed recovery of rod photoresponse in mice lacking the GTPase accelerating protein RGS9-1.Q41719683
RGS6, RGS7, RGS9, and RGS11 stimulate GTPase activity of Gi family G-proteins with differential selectivity and maximal activityQ42049270
RGS9 modulates dopamine signaling in the basal gangliaQ42443389
RGS7 complex formation and colocalization with the Gbeta5 subunit in the adult rat brain and influence on Gbeta5gamma2-mediated PLCbeta signalingQ42485202
RGS9-1 is required for normal inactivation of mouse cone phototransductionQ43550275
Specific binding of RGS9-Gbeta 5L to protein anchor in photoreceptor membranes greatly enhances its catalytic activityQ43990174
Up-regulation of regulator of G protein signaling 4 expression in a model of neuropathic pain and insensitivity to morphineQ44327442
Gbeta5 is required for normal light responses and morphology of retinal ON-bipolar cells.Q44934687
RGS expression rate-limits recovery of rod photoresponsesQ46175317
Analysis of genetic variations in the RGS9 gene and antipsychotic-induced tardive dyskinesia in schizophreniaQ46544382
Expression and localization of RGS9-2/G 5/R7BP complex in vivo is set by dynamic control of its constitutive degradation by cellular cysteine proteases.Q46840630
Endogenous RGS proteins and Galpha subtypes differentially control muscarinic and adenosine-mediated chronotropic effects.Q46925910
Resistance to diet-induced obesity and improved insulin sensitivity in mice with a regulator of G protein signaling-insensitive G184S Gnai2 allele.Q46956815
Gene expression changes in peripheral mononuclear cells from schizophrenic patients treated with a combination of antipsychotic with fluvoxamineQ48091465
Consistent with dopamine supersensitivity, RGS9 expression is diminished in the amphetamine-treated animal model of schizophrenia and in postmortem schizophrenia brainQ48264084
Human-mouse quantitative trait locus concordance and the dissection of a human neuroticism locus.Q50878855
Rgs 2 gene polymorphisms as modulators of anxiety in humans?Q50936324
Genetic dissection of a behavioral quantitative trait locus shows that Rgs2 modulates anxiety in mice.Q50989320
Association of the RGS2 gene with extrapyramidal symptoms induced by treatment with antipsychotic medicationQ51902733
Endogenous RGS proteins modulate SA and AV nodal functions in isolated heart: implications for sick sinus syndrome and AV blockQ52576782
An N-terminal region of Caenorhabditis elegans RGS proteins EGL-10 and EAT-16 directs inhibition of G(alpha)o versus G(alpha)q signalingQ78299290
Activation of RGS9-1GTPase acceleration by its membrane anchor, R9APQ78863307
Localization and differential interaction of R7 RGS proteins with their membrane anchors R7BP and R9AP in neurons of vertebrate retinaQ80177636
Kinetic mechanism of RGS9-1 potentiation by R9APQ80182004
R7BP, a novel neuronal protein interacting with RGS proteins of the R7 familyQ81230034
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectG protein-coupled receptorQ38173
P304page(s)17-24
P577publication date2008-11-29
P13046publication type of scholarly workreview articleQ7318358
P1433published inTrends in Pharmacological SciencesQ2451474
P1476titleR9AP and R7BP: traffic cops for the RGS7 family in phototransduction and neuronal GPCR signaling
P478volume30

Reverse relations

cites work (P2860)
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