scholarly article | Q13442814 |
P2093 | author name string | Hao Zhou | |
Kendall J Blumer | |||
Matthew D Cain | |||
Muralidharan Jayaraman | |||
Lixia Jia | |||
P2860 | cites work | Six Patients with Bradyopsia (Slow Vision) | Q24262222 |
Generation and characterization of Rgs4 mutant mice | Q24523661 | ||
R9AP, a membrane anchor for the photoreceptor GTPase accelerating protein, RGS9-1 | Q24533588 | ||
High expression levels in cones of RGS9, the predominant GTPase accelerating protein of rods | Q24569573 | ||
Motor coordination deficits in mice lacking RGS9 | Q24648527 | ||
Essential role for RGS9 in opiate action | Q24655663 | ||
Instability of GGL domain-containing RGS proteins in mice lacking the G protein beta-subunit Gbeta5 | Q24670878 | ||
Crystal structure of the multifunctional Gβ5–RGS9 complex | Q27649555 | ||
Regulators of G protein signaling 6 and 7. Purification of complexes with gbeta5 and assessment of their effects on g protein-mediated signaling pathways | Q28116135 | ||
RGS7 is palmitoylated and exists as biochemically distinct forms | Q28141269 | ||
Nuclear localization of G protein beta 5 and regulator of G protein signaling 7 in neurons and brain | Q28142336 | ||
GTPase-activating proteins for heterotrimeric G proteins: regulators of G protein signaling (RGS) and RGS-like proteins | Q28145018 | ||
The DEP Domain Determines Subcellular Targeting of the GTPase Activating Protein RGS9In Vivo | Q28183847 | ||
G beta 5.RGS7 inhibits G alpha q-mediated signaling via a direct protein-protein interaction | Q28188095 | ||
Defects in RGS9 or its anchor protein R9AP in patients with slow photoreceptor deactivation | Q28236836 | ||
A role of RGS proteins in drug addiction | Q28249710 | ||
Regulators of G-Protein Signaling (RGS) Proteins: Region-Specific Expression of Nine Subtypes in Rat Brain | Q28250219 | ||
R7BP augments the function of RGS7*Gbeta5 complexes by a plasma membrane-targeting mechanism | Q28254091 | ||
Palmitoylation of intracellular signaling proteins: regulation and function | Q28266189 | ||
Identification of small-molecule inhibitors of RGS4 using a high-throughput flow cytometry protein interaction assay | Q28266287 | ||
EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteins | Q28272431 | ||
Goalpha regulates volatile anesthetic action in Caenorhabditis elegans | Q28366737 | ||
Absence of the RGS9.Gbeta5 GTPase-activating complex in photoreceptors of the R9AP knockout mouse | Q28505673 | ||
Palmitoylation regulates plasma membrane-nuclear shuttling of R7BP, a novel membrane anchor for the RGS7 family | Q28512296 | ||
Differential expression of the regulator of G protein signaling RGS9 protein in nociceptive pathways of different age rats | Q28577511 | ||
RGS9-2 modulates D2 dopamine receptor-mediated Ca2+ channel inhibition in rat striatal cholinergic interneurons | Q28578625 | ||
Brain-specific RGS9-2 is localized to the nucleus via its unique proline-rich domain | Q28580061 | ||
Complexes of the G protein subunit gbeta 5 with the regulators of G protein signaling RGS7 and RGS9. Characterization in native tissues and in transfected cells | Q28583318 | ||
The GTPase activating factor for transducin in rod photoreceptors is the complex between RGS9 and type 5 G protein beta subunit | Q28609908 | ||
RGS9, a GTPase accelerator for phototransduction | Q28610017 | ||
Cellular regulation of RGS proteins: modulators and integrators of G protein signaling | Q28646133 | ||
Cloning and characterization of RGS9-2: a striatal-enriched alternatively spliced product of the RGS9 gene | Q30653116 | ||
Copurification of brain G-protein beta5 with RGS6 and RGS7. | Q30834724 | ||
Expression patterns of the RGS9-1 anchoring protein R9AP in the chicken and mouse suggest multiple roles in the nervous system | Q31031856 | ||
RGS9: A regulator of G-protein signalling with specific expression in rat and mouse striatum | Q32066784 | ||
Ethnic stratification of the association of RGS4 variants with antipsychotic treatment response in schizophrenia. | Q33288672 | ||
SNAREs and the specificity of membrane fusion | Q34221149 | ||
D2 dopamine receptors colocalize regulator of G-protein signaling 9-2 (RGS9-2) via the RGS9 DEP domain, and RGS9 knock-out mice develop dyskinesias associated with dopamine pathways. | Q34397299 | ||
Psychosis pathways converge via D2high dopamine receptors | Q34540180 | ||
The loss of the PDE6 deactivating enzyme, RGS9, results in precocious light adaptation at low light levels | Q34758194 | ||
Regulators of G protein signaling (RGS proteins): novel central nervous system drug targets | Q35015775 | ||
Pleiotropic phenotype of a genomic knock-in of an RGS-insensitive G184S Gnai2 allele | Q35071259 | ||
Antagonism between G(o)alpha and G(q)alpha in Caenorhabditis elegans: the RGS protein EAT-16 is necessary for G(o)alpha signaling and regulates G(q)alpha activity | Q35201877 | ||
Desensitization of G protein-coupled receptors and neuronal functions | Q35817048 | ||
RGS-insensitive G-protein mutations to study the role of endogenous RGS proteins | Q35864233 | ||
Regulators of G protein signaling & drugs of abuse. | Q36056317 | ||
Mechanisms of vertebrate synaptogenesis | Q36196530 | ||
Postnatal induction and localization of R7BP, a membrane-anchoring protein for regulator of G protein signaling 7 family-Gbeta5 complexes in brain | Q36539488 | ||
A role for rhodopsin in a signal transduction cascade that regulates membrane trafficking and photoreceptor polarity | Q36607636 | ||
Gbeta5-RGS complexes co-localize with mGluR6 in retinal ON-bipolar cells | Q36731468 | ||
Pharmacogenomics of G protein-coupled receptor signaling: insights from health and disease | Q37120554 | ||
Intramolecular interaction between the DEP domain of RGS7 and the Gbeta5 subunit | Q38301611 | ||
Olanzapine increases RGS7 protein expression via stimulation of the Janus tyrosine kinase-signal transducer and activator of transcription signaling cascade. | Q40152916 | ||
Subcellular targeting of RGS9-2 is controlled by multiple molecular determinants on its membrane anchor, R7BP. | Q40297867 | ||
Slowed recovery of rod photoresponse in mice lacking the GTPase accelerating protein RGS9-1. | Q41719683 | ||
RGS6, RGS7, RGS9, and RGS11 stimulate GTPase activity of Gi family G-proteins with differential selectivity and maximal activity | Q42049270 | ||
RGS9 modulates dopamine signaling in the basal ganglia | Q42443389 | ||
RGS7 complex formation and colocalization with the Gbeta5 subunit in the adult rat brain and influence on Gbeta5gamma2-mediated PLCbeta signaling | Q42485202 | ||
RGS9-1 is required for normal inactivation of mouse cone phototransduction | Q43550275 | ||
Specific binding of RGS9-Gbeta 5L to protein anchor in photoreceptor membranes greatly enhances its catalytic activity | Q43990174 | ||
Up-regulation of regulator of G protein signaling 4 expression in a model of neuropathic pain and insensitivity to morphine | Q44327442 | ||
Gbeta5 is required for normal light responses and morphology of retinal ON-bipolar cells. | Q44934687 | ||
RGS expression rate-limits recovery of rod photoresponses | Q46175317 | ||
Analysis of genetic variations in the RGS9 gene and antipsychotic-induced tardive dyskinesia in schizophrenia | Q46544382 | ||
Expression and localization of RGS9-2/G 5/R7BP complex in vivo is set by dynamic control of its constitutive degradation by cellular cysteine proteases. | Q46840630 | ||
Endogenous RGS proteins and Galpha subtypes differentially control muscarinic and adenosine-mediated chronotropic effects. | Q46925910 | ||
Resistance to diet-induced obesity and improved insulin sensitivity in mice with a regulator of G protein signaling-insensitive G184S Gnai2 allele. | Q46956815 | ||
Gene expression changes in peripheral mononuclear cells from schizophrenic patients treated with a combination of antipsychotic with fluvoxamine | Q48091465 | ||
Consistent with dopamine supersensitivity, RGS9 expression is diminished in the amphetamine-treated animal model of schizophrenia and in postmortem schizophrenia brain | Q48264084 | ||
Human-mouse quantitative trait locus concordance and the dissection of a human neuroticism locus. | Q50878855 | ||
Rgs 2 gene polymorphisms as modulators of anxiety in humans? | Q50936324 | ||
Genetic dissection of a behavioral quantitative trait locus shows that Rgs2 modulates anxiety in mice. | Q50989320 | ||
Association of the RGS2 gene with extrapyramidal symptoms induced by treatment with antipsychotic medication | Q51902733 | ||
Endogenous RGS proteins modulate SA and AV nodal functions in isolated heart: implications for sick sinus syndrome and AV block | Q52576782 | ||
An N-terminal region of Caenorhabditis elegans RGS proteins EGL-10 and EAT-16 directs inhibition of G(alpha)o versus G(alpha)q signaling | Q78299290 | ||
Activation of RGS9-1GTPase acceleration by its membrane anchor, R9AP | Q78863307 | ||
Localization and differential interaction of R7 RGS proteins with their membrane anchors R7BP and R9AP in neurons of vertebrate retina | Q80177636 | ||
Kinetic mechanism of RGS9-1 potentiation by R9AP | Q80182004 | ||
R7BP, a novel neuronal protein interacting with RGS proteins of the R7 family | Q81230034 | ||
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | G protein-coupled receptor | Q38173 |
P304 | page(s) | 17-24 | |
P577 | publication date | 2008-11-29 | |
P13046 | publication type of scholarly work | review article | Q7318358 |
P1433 | published in | Trends in Pharmacological Sciences | Q2451474 |
P1476 | title | R9AP and R7BP: traffic cops for the RGS7 family in phototransduction and neuronal GPCR signaling | |
P478 | volume | 30 |
Q40353644 | A central role for R7bp in the regulation of itch sensation |
Q36115328 | A finer tuning of G-protein signaling through regulated control of RGS proteins |
Q37608581 | A mechanism regulating G protein-coupled receptor signaling that requires cycles of protein palmitoylation and depalmitoylation |
Q36141986 | A unique role of RGS9-2 in the striatum as a positive or negative regulator of opiate analgesia |
Q28742338 | Association between regulator of G protein signaling 9-2 and body weight |
Q90152498 | Development of R7BP inhibitors through cross-linking coupled mass spectrometry and integrated modeling |
Q34219347 | Differential effects of the Gβ5-RGS7 complex on muscarinic M3 receptor-induced Ca2+ influx and release. |
Q48268252 | Evolution of the shut-off steps of vertebrate phototransduction |
Q36069404 | Expression of the Gβ5/R7-RGS protein complex in pituitary and pancreatic islet cells |
Q36471320 | GIRK channel modulation by assembly with allosterically regulated RGS proteins |
Q24605032 | GPR158/179 regulate G protein signaling by controlling localization and activity of the RGS7 complexes |
Q91843123 | Genetic characterization and long-term management of severely affected siblings with intellectual developmental disorder with cardiac arrhythmia syndrome |
Q34787455 | Gi/o Signaling and the Palmitoyltransferase DHHC2 Regulate Palmitate Cycling and Shuttling of RGS7 Family-binding Protein |
Q44334646 | Gβ2 and Gβ4 participate in the opioid and adrenergic receptor‐mediated Ca2+ channel modulation in rat sympathetic neurons |
Q35053995 | Helix 8 and the i3 loop of the muscarinic M3 receptor are crucial sites for its regulation by the Gβ5-RGS7 complex |
Q37726386 | Identification of ligands targeting RGS proteins high-throughput screening and therapeutic potential |
Q57471606 | Inhibitory signaling to ion channels in hippocampal neurons is differentially regulated by alternative macromolecular complexes of RGS7 |
Q35341465 | Knockout of G protein β5 impairs brain development and causes multiple neurologic abnormalities in mice |
Q37132059 | Macromolecular Composition Dictates Receptor and G Protein Selectivity of Regulator of G Protein Signaling (RGS) 7 and 9-2 Protein Complexes in Living Cells |
Q41786890 | Membrane anchoring subunits specify selective regulation of RGS9·Gbeta5 GAP complex in photoreceptor neurons |
Q35513856 | Membrane attachment is key to protecting transducin GTPase-activating complex from intracellular proteolysis in photoreceptors |
Q41881375 | Molecular organization of the complex between the muscarinic M3 receptor and the regulator of G protein signaling, Gbeta(5)-RGS7. |
Q64978263 | Multivariate analysis of genome-wide data to identify potential pleiotropic genes for five major psychiatric disorders using MetaCCA. |
Q33932409 | Nuclear localization of the G protein beta 5/R7-regulator of G protein signaling protein complex is dependent on R7 binding protein |
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Q37327676 | Overexpression of regulator of G protein signaling 11 promotes cell migration and associates with advanced stages and aggressiveness of lung adenocarcinoma. |
Q35760250 | R7BP Modulates Opiate Analgesia and Tolerance but not Withdrawal |
Q28396194 | R7BP complexes with RGS9-2 and RGS7 in the striatum differentially control motor learning and locomotor responses to cocaine |
Q48655186 | RGS Proteins Maintain Robustness of GPCR-GIRK Coupling by Selective Stimulation of the G Protein Subunit Gα o |
Q37705804 | RGS7/Gβ5/R7BP complex regulates synaptic plasticity and memory by modulating hippocampal GABABR-GIRK signaling. |
Q39027669 | RGS9-2 Modulates Responses to Oxycodone in Pain-Free and Chronic Pain States |
Q36056818 | RGS9-2--controlled adaptations in the striatum determine the onset of action and efficacy of antidepressants in neuropathic pain states |
Q30492826 | RSBP-1 is a membrane-targeting subunit required by the Galpha(q)-specific but not the Galpha(o)-specific R7 regulator of G protein signaling in Caenorhabditis elegans |
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Q35523846 | Regulators of G Protein Signaling (RGS) Proteins as Drug Targets: Modulating G-Protein-Coupled Receptor (GPCR) Signal Transduction |
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Q37726364 | Structure, function, and localization of Gβ5-RGS complexes |
Q35497109 | Targeted deletion of one or two copies of the G protein β subunit Gβ5 gene has distinct effects on body weight and behavior in mice |
Q41763474 | The Gbeta5-RGS7 complex selectively inhibits muscarinic M3 receptor signaling via the interaction between the third intracellular loop of the receptor and the DEP domain of RGS7 |
Q30397640 | The evolution of regulators of G protein signalling proteins as drug targets - 20 years in the making: IUPHAR Review 21. |
Q34310119 | Thinking outside of the "RGS box": new approaches to therapeutic targeting of regulators of G protein signaling. |
Q37335060 | Timing is everything: GTPase regulation in phototransduction. |
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