| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1052695378 |
| P356 | DOI | 10.1186/1750-1326-4-35 |
| P932 | PMC publication ID | 2739857 |
| P698 | PubMed publication ID | 19695092 |
| P5875 | ResearchGate publication ID | 26755606 |
| P2093 | author name string | Makoto Michikawa | |
| Atsushi Watanabe | |||
| Takashi Hosono | |||
| Toshiyuki Nakamura | |||
| Takahiro Fujino | |||
| P2860 | cites work | Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B,E(LDL) receptors in the brain. | Q46034439 |
| Apolipoprotein E localization in rat hepatocytes by immunogold labeling of cryothin sections | Q46044805 | ||
| Fluorescence resonance energy transfer analysis of apolipoprotein E C-terminal domain and amyloid beta peptide (1-42) interaction | Q46478601 | ||
| Mitochondrial Abeta: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease | Q47714762 | ||
| Differential generation of high-density lipoprotein by endogenous and exogenous apolipoproteins in cultured fetal rat astrocytes | Q48198240 | ||
| Effect of carboxyl-terminal truncation on structure and lipid interaction of human apolipoprotein E4. | Q48603774 | ||
| Beta-amyloid peptide interacts specifically with the carboxy-terminal domain of human apolipoprotein E: relevance to Alzheimer's disease | Q49171338 | ||
| The intracellular fate of apolipoprotein E is tau dependent and apoe allele-specific. | Q53213425 | ||
| Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation. | Q53335187 | ||
| Apolipoprotein E exhibits isoform-specific promotion of lipid efflux from astrocytes and neurons in culture | Q73491113 | ||
| Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease | Q22248076 | ||
| Apolipoprotein E (ApoE) isoform-dependent lipid release from astrocytes prepared from human ApoE3 and ApoE4 knock-in mice | Q24298652 | ||
| Molecular interactions between apoE and ABCA1: impact on apoE lipidation | Q24306797 | ||
| Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families | Q27860677 | ||
| Polymorphism in the cholesterol 24S-hydroxylase gene is associated with Alzheimer's disease | Q28201917 | ||
| Increased brain beta-amyloid load, phosphorylated tau, and risk of Alzheimer disease associated with an intronic CYP46 polymorphism | Q28203757 | ||
| Apolipoprotein E: far more than a lipid transport protein | Q28204471 | ||
| Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium | Q28252389 | ||
| Apolipoprotein E: cholesterol transport protein with expanding role in cell biology | Q28294791 | ||
| Apolipoprotein E: from atherosclerosis to Alzheimer's disease and beyond | Q33702396 | ||
| Intracellular APP processing and A beta production in Alzheimer disease | Q33710829 | ||
| Intracellular biology of Alzheimer's disease amyloid beta peptide | Q33827283 | ||
| Apolipoproteins in human cerebrospinal fluid | Q33976139 | ||
| Lipid- and receptor-binding regions of apolipoprotein E4 fragments act in concert to cause mitochondrial dysfunction and neurotoxicity | Q34210006 | ||
| Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo | Q34514599 | ||
| Chylomicron remnant metabolism. Role of hepatic lipoprotein receptors in mediating uptake | Q35385524 | ||
| Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology | Q35747757 | ||
| Novel action of apolipoprotein E (ApoE): ApoE isoform specifically inhibits lipid-particle-mediated cholesterol release from neurons | Q35808508 | ||
| Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice | Q35978742 | ||
| The Alzheimer's disease beta-secretase enzyme, BACE1. | Q36397690 | ||
| Apolipoprotein E fragments present in Alzheimer's disease brains induce neurofibrillary tangle-like intracellular inclusions in neurons | Q37117670 | ||
| Rapid endocytosis of the low density lipoprotein receptor-related protein modulates cell surface distribution and processing of the beta-amyloid precursor protein. | Q40459820 | ||
| Impaired recycling of apolipoprotein E4 is associated with intracellular cholesterol accumulation. | Q40504133 | ||
| Apolipoprotein E4 domain interaction occurs in living neuronal cells as determined by fluorescence resonance energy transfer | Q40571686 | ||
| Apolipoprotein E affects the rate of Alzheimer disease expression: beta-amyloid burden is a secondary consequence dependent on APOE genotype and duration of disease | Q40701616 | ||
| A test of the cytosolic apolipoprotein E hypothesis fails to detect the escape of apolipoprotein E from the endocytic pathway into the cytosol and shows that direct expression of apolipoprotein E in the cytosol is cytotoxic. | Q40965861 | ||
| Intracellular accumulation of beta-amyloid in cells expressing the Swedish mutant amyloid precursor protein. | Q41271824 | ||
| A monomeric human apolipoprotein E carboxyl-terminal domain | Q42625731 | ||
| CNS synaptogenesis promoted by glia-derived cholesterol | Q43794738 | ||
| ABCA1 modulates CSF cholesterol levels and influences the age at onset of Alzheimer's disease | Q44324469 | ||
| Glial lipoproteins stimulate axon growth of central nervous system neurons in compartmented cultures | Q44717175 | ||
| Neuron-specific apolipoprotein e4 proteolysis is associated with increased tau phosphorylation in brains of transgenic mice. | Q44795511 | ||
| P921 | main subject | mitochondrion | Q39572 |
| P304 | page(s) | 35 | |
| P577 | publication date | 2009-08-20 | |
| P1433 | published in | Molecular Neurodegeneration | Q15817329 |
| P1476 | title | Apolipoprotein E4 (1-272) fragment is associated with mitochondrial proteins and affects mitochondrial function in neuronal cells | |
| P478 | volume | 4 |
| Q34034409 | APOE and neuroenergetics: an emerging paradigm in Alzheimer's disease |
| Q26741633 | APOE genotype and stress response - a mini review |
| Q90170632 | APOE4 is Associated with Differential Regional Vulnerability to Bioenergetic Deficits in Aged APOE Mice |
| Q39810517 | Altered Energy Metabolism Pathways in the Posterior Cingulate in Young Adult Apolipoprotein E ɛ4 Carriers |
| Q97692597 | Altered mitochondrial dynamics and function in APOE4-expressing astrocytes |
| Q30539979 | ApoE4 induces Aβ42, tau, and neuronal pathology in the hippocampus of young targeted replacement apoE4 mice |
| Q34761039 | ApoE4 induces synaptic and ERG impairments in the retina of young targeted replacement apoE4 mice |
| Q33813945 | Apolipoprotein E - A Multifunctional Protein with Implications in Various Pathologies as a Result of Its Structural Features |
| Q37691070 | Apolipoprotein E as a β-amyloid-independent factor in Alzheimer's disease. |
| Q39625718 | Apolipoprotein E4 domain interaction mediates detrimental effects on mitochondria and is a potential therapeutic target for Alzheimer disease |
| Q34497951 | Apolipoprotein E: From lipid transport to neurobiology |
| Q36963238 | Apolipoprotein e sets the stage: response to injury triggers neuropathology |
| Q89841154 | Beyond the CNS: The many peripheral roles of APOE |
| Q97692894 | Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing |
| Q52955414 | Chromosomal DNA damage in APOE ɛ4 carriers and noncarriers does not appear to be different. |
| Q53217399 | Endogenous Apolipoprotein E (ApoE) Fragmentation Is Linked to Amyloid Pathology in Transgenic Mouse Models of Alzheimer's Disease. |
| Q33811283 | Evidence for somatic gene conversion and deletion in bipolar disorder, Crohn's disease, coronary artery disease, hypertension, rheumatoid arthritis, type-1 diabetes, and type-2 diabetes |
| Q35133505 | Extracellular proteolysis of apolipoprotein E (apoE) by secreted serine neuronal protease |
| Q37313065 | Following Activation of the Amyloid Cascade, Apolipoprotein E4 Drives the in vivo Oligomerization of Amyloid-β Resulting in Neurodegeneration |
| Q35276630 | HIV effects on age-associated neurocognitive dysfunction: premature cognitive aging or neurodegenerative disease? |
| Q34352230 | Homocysteine, Another Risk Factor for Alzheimer Disease, Impairs Apolipoprotein E3 Function |
| Q24317038 | Interactome mapping suggests new mechanistic details underlying Alzheimer's disease |
| Q35898628 | Mitochondria and cell bioenergetics: increasingly recognized components and a possible etiologic cause of Alzheimer's disease |
| Q91982308 | Mitochondrial Dysfunction and Stress Responses in Alzheimer's Disease |
| Q60949053 | Mitochondrial Metabolism in Major Neurological Diseases |
| Q38607493 | Mitochondrial dysfunction: the missing link between aging and sporadic Alzheimer's disease |
| Q64067093 | Neuronal Apolipoprotein E4 Expression Results in Proteome-Wide Alterations and Compromises Bioenergetic Capacity by Disrupting Mitochondrial Function |
| Q27011311 | Proteolytic cleavage of apolipoprotein E4 as the keystone for the heightened risk associated with Alzheimer's disease |
| Q28730678 | Proteomic analysis of mitochondria in APOE transgenic mice and in response to an ischemic challenge |
| Q35072027 | Reduced Posterior Cingulate Mitochondrial Activity in Expired Young Adult Carriers of the APOE ε4 Allele, the Major Late-Onset Alzheimer's Susceptibility Gene |
| Q26864926 | Reevaluating Metabolism in Alzheimer's Disease from the Perspective of the Astrocyte-Neuron Lactate Shuttle Model |
| Q46019370 | Roles of apolipoprotein E4 (ApoE4) in the pathogenesis of Alzheimer's disease: lessons from ApoE mouse models. |
| Q37656554 | The Alzheimer's disease mitochondrial cascade hypothesis: progress and perspectives |
| Q38646489 | The Biological Foundation of the Genetic Association of TOMM40 with Late-onset Alzheimer's disease. |
| Q35137172 | The Broad Impact of TOM40 on Neurodegenerative Diseases in Aging |
| Q38959290 | The Complex Role of Apolipoprotein E in Alzheimer's Disease: an Overview and Update |
| Q64087216 | The Genetic Variability of in Different Human Populations and Its Implications for Longevity |
| Q38184783 | The dark sides of amyloid in Alzheimer's disease pathogenesis |
| Q91743602 | The role of APOE4 in Alzheimer's disease: strategies for future therapeutic interventions |
| Q28742884 | The ε3 and ε4 alleles of human APOE differentially affect tau phosphorylation in hyperinsulinemic and pioglitazone treated mice |
| Q39627759 | Towards Alzheimer's root cause: ECSIT as an integrating hub between oxidative stress, inflammation and mitochondrial dysfunction. Hypothetical role of the adapter protein ECSIT in familial and sporadic Alzheimer's disease pathogenesis |
Search more.