CovR Regulates Streptococcus mutans Susceptibility To Complement Immunity and Survival in Blood.

scientific article published on 29 August 2016

CovR Regulates Streptococcus mutans Susceptibility To Complement Immunity and Survival in Blood. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/IAI.00406-16
P932PMC publication ID5067753
P698PubMed publication ID27572331

P50authorRafael N StippQ82460960
Renata O Mattos-GranerQ38318183
P2093author name stringRyota Nomura
Kazuhiko Nakano
Flávia S Mariano
Erika N Harth-Chu
Lívia A Alves
P2860cites workConstruction of region-specific partial duplication mutants (merodiploid mutants) to identify the regulatory gene for the glucan-binding protein C gene in vivo in Streptococcus mutansQ73764370
Water-insoluble glucan synthesis by mutans streptococcal strains correlates with caries incidence in 12- to 30-month-old childrenQ73981702
Attenuation of glucan-binding protein C reduces the cariogenicity of Streptococcus mutans: analysis of strains isolated from human bloodQ74410194
Streptococcus mutans binding to solid phase dextran mediated by the glucan-binding protein CQ74471341
Serotype distribution of Streptococcus mutans a pathogen of dental caries in cardiovascular specimens from Japanese patientsQ79997398
Contribution of cell surface protein antigen PAc of Streptococcus mutans to bacteremiaQ82405458
Identification and characterization of a collagen-binding protein, Cbm, in Streptococcus mutansQ84514342
Genome sequence of Streptococcus mutans UA159, a cariogenic dental pathogenQ22066245
Comparative functional evolution of human and mouse CR1 and CR2Q24613139
A structural basis for the allosteric regulation of non-hydrolysing UDP-GlcNAc 2-epimerasesQ24646011
Genome-wide analysis of group a streptococci reveals a mutation that modulates global phenotype and disease specificityQ25257695
The structure of UDP-N-acetylglucosamine 2-epimerase reveals homology to phosphoglycosyl transferasesQ27628806
Complement. First of two partsQ28210663
Human complement control and complement evasion by pathogenic microbes--tipping the balanceQ28293689
Downregulation of GbpB, a component of the VicRK regulon, affects biofilm formation and cell surface characteristics of Streptococcus mutansQ28485480
Tracing the domestication of a biofilm-forming bacteriumQ28488880
Isolation and characterization of C-reactive protein and serum amyloid P component in the ratQ28582755
Regulation of gbpC expression in Streptococcus mutansQ29346577
Resistance to mucosal lysozyme compensates for the fitness deficit of peptidoglycan modifications by Streptococcus pneumoniaeQ33392682
Complement evasion by human pathogensQ33623972
A VicRK signal transduction system in Streptococcus mutans affects gtfBCD, gbpB, and ftf expression, biofilm formation, and genetic competence developmentQ33855596
CovR-controlled global regulation of gene expression in Streptococcus mutansQ33927287
Staphylococcus aureus cap5P encodes a UDP-N-acetylglucosamine 2-epimerase with functional redundancy.Q33992673
Complement and its role in innate and adaptive immune responsesQ34088142
The classical pathway is the dominant complement pathway required for innate immunity to Streptococcus pneumoniae infection in miceQ34164122
Phagocytosis of microbes: complexity in actionQ34542300
The two faces of Janus: virulence gene regulation by CovR/S in group A streptococciQ34610842
CovR and VicRK regulate cell surface biogenesis genes required for biofilm formation in Streptococcus mutans.Q34647976
Phenotypic heterogeneity of genomically-diverse isolates of Streptococcus mutansQ34684303
Biology of Streptococcus mutans-derived glucosyltransferases: role in extracellular matrix formation of cariogenic biofilmsQ34746465
Detection of oral bacteria in cardiovascular specimensQ34914547
The Streptococcus pneumoniae capsule inhibits complement activity and neutrophil phagocytosis by multiple mechanismsQ35015208
Group A Streptococcus transcriptome dynamics during growth in human blood reveals bacterial adaptive and survival strategiesQ35083669
Glucan-binding proteins of the oral streptococciQ35134880
Effect of an orphan response regulator on Streptococcus mutans sucrose-dependent adherence and cariogenesisQ35165106
Demonstration of Streptococcus mutans with a cell wall polysaccharide specific to a new serotype, k, in the human oral cavityQ35551956
Streptococcus mutans clonal variation revealed by multilocus sequence typingQ35947522
An in vitro adherence assay reveals that Helicobacter pylori exhibits cell lineage-specific tropism in the human gastric epitheliumQ36147938
Natural IgM mediates complement-dependent uptake of Francisella tularensis by human neutrophils via complement receptors 1 and 3 in nonimmune serumQ36218553
PspA and PspC minimize immune adherence and transfer of pneumococci from erythrocytes to macrophages through their effects on complement activationQ36313963
Available carbon source influences the resistance of Neisseria meningitidis against complementQ36402993
FcgammaRIIb balances efficient pathogen clearance and the cytokine-mediated consequences of sepsis.Q36403918
Involvement of sensor kinases in the stress tolerance response of Streptococcus mutansQ36422308
Variation in the group B Streptococcus CsrRS regulon and effects on pathogenicityQ36483768
Streptococcus pneumoniae capsular serotype invasiveness correlates with the degree of factor H binding and opsonization with C3b/iC3bQ36506103
Evolutionary and population genomics of the cavity causing bacteria Streptococcus mutansQ36701991
Impaired opsonization with C3b and phagocytosis of Streptococcus pneumoniae in sera from subjects with defects in the classical complement pathwayQ36804267
Streptococcus pyogenes Employs Strain-dependent Mechanisms of C3b Inactivation to Inhibit Phagocytosis and Killing of BacteriaQ36884841
Complement-mediated opsonization of invasive group A Streptococcus pyogenes strain AP53 is regulated by the bacterial two-component cluster of virulence responder/sensor (CovRS) systemQ37189577
Exocytosis acts as a modulator of the ILT4-mediated inhibition of neutrophil functionsQ37276476
Versatility of choline metabolism and choline-binding proteins in Streptococcus pneumoniae and commensal streptococciQ37461177
Complement evasion strategies of pathogens-acquisition of inhibitors and beyondQ37499399
Serotype classification of Streptococcus mutans and its detection outside the oral cavityQ37590322
Roles of oral bacteria in cardiovascular diseases--from molecular mechanisms to clinical cases: Cell-surface structures of novel serotype k Streptococcus mutans strains and their correlation to virulenceQ37760675
Capsules of Streptococcus pneumoniae and other bacteria: paradigms for polysaccharide biosynthesis and regulationQ37896640
Regulation of the glucosyltransferase (gtfBC) operon by CovR in Streptococcus mutansQ38316569
A two-component regulatory system, CsrR-CsrS, represses expression of three Streptococcus pyogenes virulence factors, hyaluronic acid capsule, streptolysin S, and pyrogenic exotoxin B.Q39512321
Species of alpha-hemolytic streptococci possessing a C-polysaccharide phosphorylcholine-containing antigen.Q40267969
Biofilm formation avoids complement immunity and phagocytosis of Streptococcus pneumoniae.Q41432621
Contribution of the interaction of Streptococcus mutans serotype k strains with fibrinogen to the pathogenicity of infective endocarditisQ41713844
The collagen-binding protein Cnm is required for Streptococcus mutans adherence to and intracellular invasion of human coronary artery endothelial cellsQ41808367
LuxS-based signaling affects Streptococcus mutans biofilm formationQ42122665
Contributions of three glycosyltransferases to sucrose-dependent adherence of Streptococcus mutansQ43763777
Spontaneous mutations in the CsrRS two-component regulatory system of Streptococcus pyogenes result in enhanced virulence in a murine model of skin and soft tissue infectionQ43834347
Impaired opsonization with complement and phagocytosis of Streptococcus pyogenes in sera from subjects with inherited C2 deficiencyQ43934864
Sucrose-derived exopolysaccharides of Streptococcus mutans V403 contribute to infectivity in endocarditisQ44553394
Contribution of glucan-binding protein C of Streptococcus mutans to bacteremia occurrenceQ44629960
Examination of the relation between periodontal health status and cardiovascular risk factors: serum total and high density lipoprotein cholesterol, C-reactive protein, and plasma fibrinogenQ44734776
Streptococcal M5 protein prevents neutrophil phagocytosis by interfering with CD11b/CD18 receptor-mediated association and signalingQ44788670
RegM is required for optimal fructosyltransferase and glucosyltransferase gene expression in Streptococcus mutansQ45121135
Transcriptional analysis of gtfB, gtfC, and gbpB and their putative response regulators in several isolates of Streptococcus mutansQ46293058
Identification of csrR/csrS, a genetic locus that regulates hyaluronic acid capsule synthesis in group A StreptococcusQ48014401
Reference distributions for immunoglobulins A, G, and M: a comparison of a large cohort to the world's literature.Q50853184
Molecular and clinical analyses of the gene encoding the collagen-binding adhesin of Streptococcus mutans.Q51776048
PCR ligation mutagenesis in transformable streptococci: application and efficiency.Q53878872
Influence of VicRK and CovR on the interactions of Streptococcus mutans with phagocytesQ60542104
Roles of the Alternative Complement Pathway and C1q during Innate Immunity to Streptococcus pyogenesQ63257860
A simple, non-invasive marker of gastric damage: sucrose permeabilityQ72674935
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectStreptococcus mutansQ131452
P304page(s)3206-3219
P577publication date2016-10-17
P1433published inInfection and ImmunityQ6029193
P1476titleCovR Regulates Streptococcus mutans Susceptibility To Complement Immunity and Survival in Blood
P478volume84

Reverse relations

cites work (P2860)
Q50020386A novel two-component system of Streptococcus sanguinis affecting functions associated with viability in saliva and biofilm formation
Q47744194Contribution of Streptococcus mutans Strains with Collagen-Binding Proteins in the Presence of Serum to the Pathogenesis of Infective Endocarditis
Q64994537CovR and VicRKX Regulate Transcription of the Collagen Binding Protein Cnm of Streptococcus mutans.
Q55322164Impact of growth pH and glucose concentrations on the CodY regulatory network in Streptococcus salivarius.
Q91670355PcsB Expression Diversity Influences on Streptococcus mitis Phenotypes Associated With Host Persistence and Virulence
Q40262634The two-component system VicRK regulates functions associated with Streptococcus mutans resistance to complement immunity.
Q46247224Two-component signal transduction systems in oral bacteria

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